Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3

Toxicon

Volumn 54, Issue 1, 2009, Pages 56-61

  Jensen, Jonas E ^a   Durek, Thomas ^a   Alewood, Paul F ^a   Adams, David J ^a   King, Glenn F ^a   Rash, Lachlan D ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Acid sensing ion channel; APETx2; Disulfide bond; Native chemical ligation; Protein folding; Solid phase peptide synthesis

Indexed keywords

ACID SENSING ION CHANNEL; APETX2 PROTEIN; DISULFIDE; PEPTIDE; PROTEIN DERIVATIVE; TOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; FEMALE; IC 50; NONHUMAN; OOCYTE; PEPTIDE SYNTHESIS; POISONOUS ANIMAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; RAT; SOLID PHASE SYNTHESIS; XENOPUS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CNIDARIAN VENOMS; DISULFIDES; ELECTROPHYSIOLOGY; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MARINE TOXINS; MASS SPECTROMETRY; NERVE TISSUE PROTEINS; OOCYTES; OXIDATION-REDUCTION; PROTEIN FOLDING; RATS; SODIUM CHANNELS; XENOPUS LAEVIS;

ACTINIARIA; ANIMALIA; ANTHOPLEURA ELEGANTISSIMA; RATTUS;

EID: 66949177983     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.03.014     Document Type: Article

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