The endoplasmic reticulum stress response is involved in apoptosis induced by aloe-emodin in HK-2 cells

Food and Chemical Toxicology

Volumn 50, Issue 3-4, 2012, Pages 1149-1158

  Zhu, Shaohua ^a   Jin, Jing ^a   Wang, Yan ^a   Ouyang, Zizhang ^a   Xi, Chen ^a   Li, Jia ^a   Qiu, Yuwen ^a   Wan, Jinzhi ^a   Huang, Min ^a   Huang, Zhiying ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Aloe emodin; Apoptosis; Endoplasmic reticulum stress; HK 2 cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ALOE EMODIN; CASPASE 3; CCAAT ENHANCER BINDING PROTEIN; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; LIPOCORTIN 5; MESSENGER RNA; PROPIDIUM IODIDE; STRESS ACTIVATED PROTEIN KINASE; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CELL ULTRASTRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA FRAGMENTATION; DRUG CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CELL; M PHASE CELL CYCLE CHECKPOINT; PROTEIN PHOSPHORYLATION; RNA SPLICING; STAINING; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ANTHRAQUINONES; APOPTOSIS; BASE SEQUENCE; BLOTTING, WESTERN; CELL CYCLE; CELL LINE; CELL SURVIVAL; DNA PRIMERS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA SPLICING; RNA, MESSENGER; TRANSCRIPTION FACTORS;

ALOE; EUKARYOTA; RATTUS; RHEUM X HYBRIDUM;

EID: 84862787382     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.12.018     Document Type: Article

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