The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behavior

Biomaterials

Volumn 33, Issue 10, 2012, Pages 2902-2915

  Yang, Seungwon ^a   Kim, Hyun Man ^a  

^a Seoul National University   (South Korea)

Author keywords

Cell adhesion; Cell proliferation; Cell signaling; Wettability

Indexed keywords

ANCHORAGE-DEPENDENT CELLS; APOPTOTIC; CELL PROLIFERATION RATE; CELL SIGNALING; CELL-CYCLE PROGRESSION; FOCAL ADHESION KINASE; HYDROPHOBIC SURFACES; INVERSE RELATIONSHIP; LOW LEVEL; MATERIAL SURFACE; MOLECULAR MECHANISM; MOLECULAR SWITCHES; PHYSICO-CHEMICALS; PROLIFERATION RATE;

ADHESION; ANCHORAGES (FOUNDATIONS); CELL ADHESION; CELL PROLIFERATION; CHEMICAL MODIFICATION; ENZYMES; HYDROPHOBICITY; ROCKS; SUBSTRATES; SURFACE CHEMISTRY; SURFACES; TISSUE; TISSUE ENGINEERING; WETTING;

CELLS;

FOCAL ADHESION KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL ANCHORAGE; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CHEMICAL MODIFICATION; CONTROLLED STUDY; CORRELATIONAL STUDY; DOWN REGULATION; ENZYME ACTIVITY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURFACE PROPERTY; UPREGULATION;

ANIMALS; CELL ADHESION; CELL LINE; CELL PROLIFERATION; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICE; OSTEOBLASTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SUSPENSIONS; UP-REGULATION;

EID: 84862777981     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.12.051     Document Type: Article

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