Rho-associated kinase (ROCK) inhibition reverses low cell activity on hydrophobic surfaces

Biochemical and Biophysical Research Communications

Volumn 386, Issue 3, 2009, Pages 499-503

  Tian, Yu Shun ^a   Kim, Hyun Jung ^a   Kim, Hyun Man ^a  

^a School of Dentistry   (South Korea)

Author keywords

Adhesion; Biomaterial; Cell cycle; Hydrophobicity; Migration; Osteoblast; Rho associated kinase; Tissue engineering; Y 27632

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BIOMATERIAL; CYCLIN A; CYCLIN D; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; POLYMER; POLYSTYRENE; RHO KINASE; RHO KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CYCLE; CELL MIGRATION; CELL PROLIFERATION; ENZYME INHIBITION; HYDROPHOBICITY; IMMUNOBLOTTING; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; TISSUE ENGINEERING;

AMIDES; ANIMALS; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; ENZYME INHIBITORS; HYDROPHOBICITY; MICE; OSTEOBLASTS; PYRIDINES; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 67650227011     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.087     Document Type: Article

References (30)

1. Chang E.J., Kim H.H., Huh J.E., Kim I.A., Ko J.S., Chung C.P., and Kim H.M. Low proliferation and high apoptosis of osteoblastic cells on hydrophobic surface are associated with defective Ras signaling. Exp. Cell Res. 303 (2005) 197-206
2. Cheng Z., and Teoh S.H. Surface modification of ultra thin poly (epsilon-caprolactone) films using acrylic acid and collagen. Biomaterials 25 (2004) 1991-2001
3. Chung T.W., Wang Y.Z., Huang Y.Y., Pan C.I., and Wang S.S. Poly (epsilon-caprolactone) grafted with nano-structured chitosan enhances growth of human dermal fibroblasts. Artif. Organs 30 (2006) 35-41
4. Ying L., Yin C., Zhuo R.X., Leong K.W., Mao H.Q., Kang E.T., and Neoh K.G. Immobilization of galactose ligands on acrylic acid graft-copolymerized poly(ethylene terephthalate) film and its application to hepatocyte culture. Biomacromolecules 4 (2003) 157-165
5. Mapili G., Lu Y., Chen S., and Roy K. Laser-layered microfabrication of spatially patterned functionalized tissue-engineering scaffolds. J. Biomed. Mater. Res. B Appl. Biomater. 75 (2005) 414-424
6. Safinia L., Datan N., Hohse M., Mantalaris A., and Bismarck A. Towards a methodology for the effective surface modification of porous polymer scaffolds. Biomaterials 26 (2005) 7537-7547
7. Riento K., and Ridley A.J. Rocks: multifunctional kinases in cell behaviour. Nat. Rev. Mol. Cell Biol. 4 (2003) 446-456
8. Leung T., Chen X.Q., Manser E., and Lim L. The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton. Mol. Cell. Biol. 16 (1996) 5313-5327
9. Loirand G., Guerin P., and Pacaud P. Rho kinases in cardiovascular physiology and pathophysiology. Circ. Res. 98 (2006) 322-334
10. Kiian I., Tkachuk N., Haller H., and Dumler I. Urokinase-induced migration of human vascular smooth muscle cells requires coupling of the small GTPases RhoA and Rac1 to the Tyk2/PI3-K signalling pathway. Thromb. Haemost. 89 (2003) 904-914
11. Rolfe B.E., Worth N.F., World C.J., Campbell J.H., and Campbell G.R. Rho and vascular disease. Atherosclerosis 183 (2005) 1-16
12. Itoh K., Yoshioka K., Akedo H., Uehata M., Ishizaki T., and Narumiya S. An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat. Med. 5 (1999) 221-225
13. Liu B., Itoh H., Louie O., Kubota K., and Kent K.C. The signaling protein Rho is necessary for vascular smooth muscle migration and survival but not for proliferation. Surgery 132 (2002) 317-325
14. Mammoto A., Huang S., Moore K., Oh P., and Ingber D.E. Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. J. Biol. Chem. 279 (2004) 26323-26330
15. Chang Y., Ceacareanu B., Dixit M., Sreejayan N., and Hassid A. Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho. Circ. Res. 91 (2002) 390-397
16. Liao J.K., Seto M., and Noma K. Rho kinase (ROCK) inhibitors. J. Cardiovasc. Pharmacol. 50 (2007) 17-24
17. Shimokawa H., and Takeshita A. Rho-kinase is an important therapeutic target in cardiovascular medicine. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 1767-1775
18. Watanabe K., Ueno M., Kamiya D., Nishiyama A., Matsumura M., Wataya T., Takahashi J.B., Nishikawa S., Nishikawa S., Muguruma K., and Sasai Y. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat. Biotechnol. 25 (2007) 681-686
19. Sander E.E., ten Klooster J.P., van Delft S., van der Kammen R.A., and Collard J.G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol. 147 (1999) 1009-1022
20. Nobes C.D., and Hall A. Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility. Biochem. Soc. Trans. 23 (1995) 456-459
21. Sherr C.J., and Roberts J.M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9 (1995) 1149-1163
22. Zhu X., Ohtsubo M., Bohmer R.M., Roberts J.M., and Assoian R.K. Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. J. Cell Biol. 133 (1996) 391-403
23. Hu W., Bellone C.J., and Baldassare J.J. RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity. J. Biol. Chem. 274 (1999) 3396-3401
24. Olson M.F., Paterson H.F., and Marshall C.J. Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1. Nature 394 (1998) 295-299
25. Croft D.R., and Olson M.F. The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms. Mol. Cell. Biol. 26 (2006) 4612-4627
26. Iwamoto H., Nakamuta M., Tada S., Sugimoto R., Enjoji M., and Nawata H. A p160ROCK-specific inhibitor, Y-27632, attenuates rat hepatic stellate cell growth. J. Hepatol. 32 (2000) 762-770
27. Yin J., and Yu F.S. Rho kinases regulate corneal epithelial wound healing. Am. J. Physiol. Cell Physiol. 295 (2008) C378-C387
28. Darenfed H., Dayanandan B., Zhang T., Hsieh S.H., Fournier A.E., and Mandato C.A. Molecular characterization of the effects of Y-27632. Cell Motil. Cytoskeleton 64 (2007) 97-109
29. Holtje M., Hoffmann A., Hofmann F., Mucke C., Grosse G., Van Rooijen N., Kettenmann H., Just I., and Ahnert-Hilger G. Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing. J. Neurochem. 95 (2005) 1237-1248
30. Koga T., Awai M., Tsutsui J., Yue B.Y., and Tanihara H. Rho-associated protein kinase inhibitor, Y-27632, induces alterations in adhesion, contraction and motility in cultured human trabecular meshwork cells. Exp. Eye Res. 82 (2006) 362-370