An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology

Acta Neuropathologica

Volumn 124, Issue 1, 2012, Pages 37-50

  Kovacs, Gabor G ^a   Wagner, Uta ^b   Dumont, Benoit ^c,d   Pikkarainen, Maria ^e   Osman, Awad A ^b   Streichenberger, Nathalie ^c   Leisser, Irene ^a   Verchère, Jérémy ^f   Baron, Thierry ^f   Alafuzoff, Irina ^e,g   Budka, Herbert ^a   Perret Liaudet, Armand ^c,d   Lachmann, Ingolf ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Roboscreen GmbH Leipzig   (Germany)

^c HOSPICES CIVILS DE LYON   (France)

^d UNIVERSITÉ LYON 1   (France)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

^f Laboratoire de Lyon   (France)

^g UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Synuclein; Biomarker; Lewy body dementia; Multiple system atrophy; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 5G4; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DIFFUSE LEWY BODY DISEASE; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MALE; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ALPHA-SYNUCLEIN; ANTIBODIES; BRAIN; BRAIN DISEASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; IMMUNOHISTOCHEMISTRY; MULTIPLE SYSTEM ATROPHY; NEURONS; PARKINSON DISEASE;

EID: 84862769983     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-012-0964-x     Document Type: Article

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