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Volumn 62, Issue 6, 2003, Pages 644-654

Accumulation of phosphorylated α-synuclein in aging human brain

Author keywords

Axon; Dementia with Lewy bodies; Immunohistochemistry; Parkinson disease; Synapse; Synucleinopathy

Indexed keywords

ALPHA SYNUCLEIN; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY;

EID: 0037604508     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/62.6.644     Document Type: Article
Times cited : (326)

References (27)
  • 1
    • 0023931333 scopus 로고
    • Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study
    • Kuzuhara S, Mori H, Izumiyama N, Yoshimura M, Ihara Y. Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study. Acta Neuropathol (Berl) 1988;75:345-53
    • (1988) Acta Neuropathol (Berl) , vol.75 , pp. 345-353
    • Kuzuhara, S.1    Mori, H.2    Izumiyama, N.3    Yoshimura, M.4    Ihara, Y.5
  • 3
    • 0031941058 scopus 로고    scopus 로고
    • Aggregation of α-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies
    • Baba M, Nakajo S, Tu PH, et al. Aggregation of α-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies. Am J Pathol 1998;152:879-84
    • (1998) Am J Pathol , vol.152 , pp. 879-884
    • Baba, M.1    Nakajo, S.2    Tu, P.H.3
  • 4
    • 0032926674 scopus 로고    scopus 로고
    • Lewy body-type degeneration in cardiac plexus in Parkinson's and incidental Lewy body diseases
    • Iwanaga K, Wakabayashi K, Yoshimoto M, et al. Lewy body-type degeneration in cardiac plexus in Parkinson's and incidental Lewy body diseases. Neurology 1999;52:1269-71
    • (1999) Neurology , vol.52 , pp. 1269-1271
    • Iwanaga, K.1    Wakabayashi, K.2    Yoshimoto, M.3
  • 6
    • 0006164301 scopus 로고    scopus 로고
    • Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop
    • McKeith IG, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology 1996;47:1113-24
    • (1996) Neurology , vol.47 , pp. 1113-1124
    • McKeith, I.G.1    Galasko, D.2    Kosaka, K.3
  • 8
    • 0002495762 scopus 로고    scopus 로고
    • Parkinson's disease and dementia
    • Esiri MM, Morris JH, eds. Cambridge: Cambridge University Press
    • Esiri MM, McShane RH. Parkinson's disease and dementia. In: Esiri MM, Morris JH, eds. The neuropathology of dementia. Cambridge: Cambridge University Press, 1997:174-93
    • (1997) The Neuropathology of Dementia , pp. 174-193
    • Esiri, M.M.1    McShane, R.H.2
  • 10
    • 18344417178 scopus 로고    scopus 로고
    • Lewy bodies contain altered α-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes
    • Lippa CF, Fujiwara H, Mann DM, et al. Lewy bodies contain altered α-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am J Pathol 1998;153:1365-70
    • (1998) Am J Pathol , vol.153 , pp. 1365-1370
    • Lippa, C.F.1    Fujiwara, H.2    Mann, D.M.3
  • 11
    • 0035847186 scopus 로고    scopus 로고
    • α-synuclein-positive structures in cases with sporadic Alzheimer's disease: Morphology and its relationship to tau aggregation
    • Arai Y, Yamazaki M, Mori O, Muramatsu H, Asano G, Katayama Y. α-Synuclein-positive structures in cases with sporadic Alzheimer's disease: Morphology and its relationship to tau aggregation. Brain Res 2001;888:287-96
    • (2001) Brain Res , vol.888 , pp. 287-296
    • Arai, Y.1    Yamazaki, M.2    Mori, O.3    Muramatsu, H.4    Asano, G.5    Katayama, Y.6
  • 12
    • 0028277520 scopus 로고
    • Identification of two distinct synucleins from human brain
    • Jakes R, Spillantini MG, Goedert M. Identification of two distinct synucleins from human brain. FEBS Lett 1994;345:27-32
    • (1994) FEBS Lett , vol.345 , pp. 27-32
    • Jakes, R.1    Spillantini, M.G.2    Goedert, M.3
  • 13
    • 0036174010 scopus 로고    scopus 로고
    • α-synuclein is phosphorylated in synucleinopathy lesions
    • Fujiwara H, Hasegawa M, Dohmae N, et al. α-Synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol 2002;4:160-64
    • (2002) Nat Cell Biol , vol.4 , pp. 160-164
    • Fujiwara, H.1    Hasegawa, M.2    Dohmae, N.3
  • 15
    • 0033595485 scopus 로고    scopus 로고
    • Report of the second dementia with Lewy body international workshop: Diagnosis and treatment
    • Consortium on Dementia with Lewy Bodies
    • McKeith IG, Perry EK, Perry RH. Report of the second dementia with Lewy body international workshop: Diagnosis and treatment. Consortium on Dementia with Lewy Bodies. Neurology 1999;53:902-5
    • (1999) Neurology , vol.53 , pp. 902-905
    • McKeith, I.G.1    Perry, E.K.2    Perry, R.H.3
  • 16
    • 2242472974 scopus 로고    scopus 로고
    • Phosphorylated α-synuclein is ubiquitinated in α-synucleinopathy lesions
    • Hasegawa M, Fujiwara H, Nonaka T, et al. Phosphorylated α-synuclein is ubiquitinated in α-synucleinopathy lesions. J Biol Chem 2002;277:49071-76
    • (2002) J Biol Chem , vol.277 , pp. 49071-49076
    • Hasegawa, M.1    Fujiwara, H.2    Nonaka, T.3
  • 17
    • 0022497390 scopus 로고
    • Spinal cord lesions in progressive supranuclear palsy: Some new observations
    • Kato T, Hirano A, Weinberg MN, Jacobs AK. Spinal cord lesions in progressive supranuclear palsy: Some new observations. Acta Neuropathol (Berl) 1986;71:11-14
    • (1986) Acta Neuropathol (Berl) , vol.71 , pp. 11-14
    • Kato, T.1    Hirano, A.2    Weinberg, M.N.3    Jacobs, A.K.4
  • 18
    • 0023111344 scopus 로고
    • Argyrophilic grains: Characteristic pathology of cerebral cortex in cases of adult onset dementia without Alzheimer changes
    • Braak H, Braak E. Argyrophilic grains: Characteristic pathology of cerebral cortex in cases of adult onset dementia without Alzheimer changes. Neurosci Lett 1987;76:124-27
    • (1987) Neurosci Lett , vol.76 , pp. 124-127
    • Braak, H.1    Braak, E.2
  • 19
    • 0033595249 scopus 로고    scopus 로고
    • Regional cerebral blood flow difference between dementia with Lewy bodies and AD
    • Ishii K, Yamaji S, Kitagaki H, Imamura T. Hirono N, Mori E. Regional cerebral blood flow difference between dementia with Lewy bodies and AD. Neurology 1999;53:413-16
    • (1999) Neurology , vol.53 , pp. 413-416
    • Ishii, K.1    Yamaji, S.2    Kitagaki, H.3    Imamura, T.4    Hirono, N.5    Mori, E.6
  • 20
    • 0030782718 scopus 로고    scopus 로고
    • Regional cerebral glucose metabolism in dementia with Lewy bodies and Alzheimer's disease: A comparative study using positron emission tomography
    • Imamura T, Ishii K, Sasaki M, et al. Regional cerebral glucose metabolism in dementia with Lewy bodies and Alzheimer's disease: A comparative study using positron emission tomography. Neurosci Lett 1997;235:49-52
    • (1997) Neurosci Lett , vol.235 , pp. 49-52
    • Imamura, T.1    Ishii, K.2    Sasaki, M.3
  • 21
    • 0036092271 scopus 로고    scopus 로고
    • Tau and α-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam
    • Forman MS, Schmidt ML. Kasturi S, Perl DP, Lee VM, Trojanowski JQ. Tau and α-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam. Am J Pathol 2002;160:1725-31
    • (2002) Am J Pathol , vol.160 , pp. 1725-1731
    • Forman, M.S.1    Schmidt, M.L.2    Kasturi, S.3    Perl, D.P.4    Lee, V.M.5    Trojanowski, J.Q.6
  • 22
    • 0034253913 scopus 로고    scopus 로고
    • Widespread expression of α-synuclein and tau immunoreactivity in Hallervorden-Spatz syndrome with protracted clinical course
    • Saito Y, Kawai M, Inoue K, et al. Widespread expression of α-synuclein and tau immunoreactivity in Hallervorden-Spatz syndrome with protracted clinical course. J Neurol Sci 2000;177:48-59
    • (2000) J Neurol Sci , vol.177 , pp. 48-59
    • Saito, Y.1    Kawai, M.2    Inoue, K.3
  • 23
    • 0036322266 scopus 로고    scopus 로고
    • Novel antibodies to synuclein show abundant striatal pathology in Lewy body disease
    • Duda JE, Giasson BI, Mabon ME, Lee VMY, Trojanowski JQ. Novel antibodies to synuclein show abundant striatal pathology in Lewy body disease. Ann Neurol 2002;52:205-10
    • (2002) Ann Neurol , vol.52 , pp. 205-210
    • Duda, J.E.1    Giasson, B.I.2    Mabon, M.E.3    Lee, V.M.Y.4    Trojanowski, J.Q.5
  • 24
    • 0032874321 scopus 로고    scopus 로고
    • Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: Rostrocaudal distribution
    • Piggott MA, Marshall EF, Thomas N, et al. Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: Rostrocaudal distribution. Brain 1999;123:1449-68
    • (1999) Brain , vol.123 , pp. 1449-1468
    • Piggott, M.A.1    Marshall, E.F.2    Thomas, N.3
  • 25
    • 0028279958 scopus 로고
    • Neocortical cholinergic activities differentiate Lewy body dementia from classical Alzheimer's disease
    • Perry EK, Haroutunian V, Davis KL, et al. Neocortical cholinergic activities differentiate Lewy body dementia from classical Alzheimer's disease. Neuroreport 1994;5:747-49
    • (1994) Neuroreport , vol.5 , pp. 747-749
    • Perry, E.K.1    Haroutunian, V.2    Davis, K.L.3
  • 27
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl) 1991;82:339-59
    • (1991) Acta Neuropathol (Berl) , vol.82 , pp. 339-359
    • Braak, H.1    Braak, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.