메뉴 건너뛰기




Volumn 131, Issue 6, 2012, Pages 843-855

Genetics of GABAergic signaling in nicotine and alcohol dependence

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; ALCOHOL; NICOTINE;

EID: 84862698928     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-011-1108-4     Document Type: Review
Times cited : (33)

References (114)
  • 4
    • 34248676586 scopus 로고    scopus 로고
    • Long-term ethanol self-administration by the nonhuman primate, Macaca fascicularis, decreases the benzodiazepine sensitivity of amygdala GABA(A) receptors
    • 17428292 1:CAS:528:DC%2BD2sXnt1aqsLc%3D 10.1111/j.1530-0277.2007.00394.x
    • NJ Anderson JB Daunais DP Friedman KA Grant BA McCool 2007 Long-term ethanol self-administration by the nonhuman primate, Macaca fascicularis, decreases the benzodiazepine sensitivity of amygdala GABA(A) receptors Alcohol Clin Exp Res 31 1061 1070 17428292 1:CAS:528:DC%2BD2sXnt1aqsLc%3D 10.1111/j.1530-0277.2007.00394.x
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 1061-1070
    • Anderson, N.J.1    Daunais, J.B.2    Friedman, D.P.3    Grant, K.A.4    McCool, B.A.5
  • 5
    • 0031799363 scopus 로고    scopus 로고
    • International union of pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: Classification on the basis of subunit structure and receptor function
    • 9647870 1:CAS:528:DyaK1cXksFCltr0%3D
    • EA Barnard P Skolnick RW Olsen H Mohler W Sieghart G Biggio C Braestrup AN Bateson SZ Langer 1998 International union of pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function Pharmacol Rev 50 291 313 9647870 1:CAS:528:DyaK1cXksFCltr0%3D
    • (1998) Pharmacol Rev , vol.50 , pp. 291-313
    • Barnard, E.A.1    Skolnick, P.2    Olsen, R.W.3    Mohler, H.4    Sieghart, W.5    Biggio, G.6    Braestrup, C.7    Bateson, A.N.8    Langer, S.Z.9
  • 6
    • 0032727358 scopus 로고    scopus 로고
    • A genome-wide search for loci contributing to smoking and alcoholism
    • 10597412
    • AW Bergen JF Korczak KA Weissbecker AM Goldstein 1999 A genome-wide search for loci contributing to smoking and alcoholism Genet Epidemiol 17 Suppl 1 S55 S60 10597412
    • (1999) Genet Epidemiol , vol.17 , Issue.SUPPL. 1
    • Bergen, A.W.1    Korczak, J.F.2    Weissbecker, K.A.3    Goldstein, A.M.4
  • 7
    • 3042546515 scopus 로고    scopus 로고
    • Molecular structure and physiological functions of GABA(B) receptors
    • 15269338 1:CAS:528:DC%2BD2cXmtlCnu74%3D 10.1152/physrev.00036.2003
    • B Bettler K Kaupmann J Mosbacher M Gassmann 2004 Molecular structure and physiological functions of GABA(B) receptors Physiol Rev 84 835 867 15269338 1:CAS:528:DC%2BD2cXmtlCnu74%3D 10.1152/physrev.00036.2003
    • (2004) Physiol Rev , vol.84 , pp. 835-867
    • Bettler, B.1    Kaupmann, K.2    Mosbacher, J.3    Gassmann, M.4
  • 8
    • 17644405816 scopus 로고    scopus 로고
    • Single- and multilocus allelic variants within the GABAB receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence
    • 15759211 1:CAS:528:DC%2BD2MXjs12rtLo%3D 10.1086/429839
    • J Beuten JZ Ma TJ Payne RT Dupont KM Crews G Somes NJ Williams RC Elston MD Li 2005 Single- and multilocus allelic variants within the GABAB receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence Am J Hum Genet 76 859 864 15759211 1:CAS:528:DC%2BD2MXjs12rtLo%3D 10.1086/429839
    • (2005) Am J Hum Genet , vol.76 , pp. 859-864
    • Beuten, J.1    Ma, J.Z.2    Payne, T.J.3    Dupont, R.T.4    Crews, K.M.5    Somes, G.6    Williams, N.J.7    Elston, R.C.8    Li, M.D.9
  • 9
    • 33845289441 scopus 로고    scopus 로고
    • Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans
    • 16713586 1:CAS:528:DC%2BD28Xht12kt7vK 10.1016/j.biopsych.2006.02.023
    • J Beuten JZ Ma TJ Payne RT Dupont XY Lou KM Crews RC Elston MD Li 2007 Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans Biol Psychiatry 61 48 55 16713586 1:CAS:528: DC%2BD28Xht12kt7vK 10.1016/j.biopsych.2006.02.023
    • (2007) Biol Psychiatry , vol.61 , pp. 48-55
    • Beuten, J.1    Ma, J.Z.2    Payne, T.J.3    Dupont, R.T.4    Lou, X.Y.5    Crews, K.M.6    Elston, R.C.7    Li, M.D.8
  • 13
    • 0037218366 scopus 로고    scopus 로고
    • Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors
    • 12488536 1:CAS:528:DC%2BD3sXjsVKj 10.1124/mol.63.1.53
    • E Cagetti J Liang I Spigelman RW Olsen 2003 Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors Mol Pharmacol 63 53 64 12488536 1:CAS:528:DC%2BD3sXjsVKj 10.1124/mol.63.1.53
    • (2003) Mol Pharmacol , vol.63 , pp. 53-64
    • Cagetti, E.1    Liang, J.2    Spigelman, I.3    Olsen, R.W.4
  • 14
    • 0034633653 scopus 로고    scopus 로고
    • The gamma-aminobutyric acid type A (GABAA) receptor-associated protein (GABARAP) promotes GABAA receptor clustering and modulates the channel kinetics
    • 10984509 1:CAS:528:DC%2BD3cXnsF2qsLk%3D 10.1073/pnas.190133497
    • L Chen H Wang S Vicini RW Olsen 2000 The gamma-aminobutyric acid type A (GABAA) receptor-associated protein (GABARAP) promotes GABAA receptor clustering and modulates the channel kinetics Proc Natl Acad Sci USA 97 11557 11562 10984509 1:CAS:528:DC%2BD3cXnsF2qsLk%3D 10.1073/pnas.190133497
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 11557-11562
    • Chen, L.1    Wang, H.2    Vicini, S.3    Olsen, R.W.4
  • 15
    • 34547118847 scopus 로고    scopus 로고
    • Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2
    • 17502375 1:CAS:528:DC%2BD2sXntFWktb0%3D 10.1074/jbc.M702111200
    • B Christiansen AK Meinild AA Jensen H Brauner-Osborne 2007 Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2 J Biol Chem 282 19331 19341 17502375 1:CAS:528:DC%2BD2sXntFWktb0%3D 10.1074/jbc.M702111200
    • (2007) J Biol Chem , vol.282 , pp. 19331-19341
    • Christiansen, B.1    Meinild, A.K.2    Jensen, A.A.3    Brauner-Osborne, H.4
  • 16
    • 10644272229 scopus 로고    scopus 로고
    • Role of GABA(B) receptor in alcohol dependence: Reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics
    • 10.1007/BF03033315
    • G Colombo G Addolorato R Agabio MA Carai F Pibiri S Serra G Vacca GL Gessa 2004 Role of GABA(B) receptor in alcohol dependence: reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics Neurotoxic Res 6 403 414 10.1007/BF03033315
    • (2004) Neurotoxic Res , vol.6 , pp. 403-414
    • Colombo, G.1    Addolorato, G.2    Agabio, R.3    Carai, M.A.4    Pibiri, F.5    Serra, S.6    Vacca, G.7    Gessa, G.L.8
  • 17
    • 0034091651 scopus 로고    scopus 로고
    • Response of nicotine self-administration in the rat to manipulations of mu-opioid and gamma-aminobutyric acid receptors in the ventral tegmental area
    • 1:CAS:528:DC%2BD3cXjtFWntbw%3D 10.1007/s002139900355
    • WA Corrigall KM Coen KL Adamson BL Chow J Zhang 2000 Response of nicotine self-administration in the rat to manipulations of mu-opioid and gamma-aminobutyric acid receptors in the ventral tegmental area Psychopharmacology (Berl) 149 107 114 1:CAS:528:DC%2BD3cXjtFWntbw%3D 10.1007/s002139900355
    • (2000) Psychopharmacology (Berl) , vol.149 , pp. 107-114
    • Corrigall, W.A.1    Coen, K.M.2    Adamson, K.L.3    Chow, B.L.4    Zhang, J.5
  • 20
    • 39149145477 scopus 로고    scopus 로고
    • Markers in the 5â€-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene
    • 17507911 1:CAS:528:DC%2BD1cXhvVyksbY%3D 10.1038/sj.npp.1301456
    • J Covault J Gelernter K Jensen R Anton HR Kranzler 2008 Markers in the 5â€-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene Neuropsychopharmacology 33 837 848 17507911 1:CAS:528:DC%2BD1cXhvVyksbY%3D 10.1038/sj.npp.1301456
    • (2008) Neuropsychopharmacology , vol.33 , pp. 837-848
    • Covault, J.1    Gelernter, J.2    Jensen, K.3    Anton, R.4    Kranzler, H.R.5
  • 21
    • 4344659001 scopus 로고    scopus 로고
    • Detecting epistatic interactions contributing to quantitative traits
    • 15305330 10.1002/gepi.20006
    • R Culverhouse T Klein W Shannon 2004 Detecting epistatic interactions contributing to quantitative traits Genet Epidemiol 27 141 152 15305330 10.1002/gepi.20006
    • (2004) Genet Epidemiol , vol.27 , pp. 141-152
    • Culverhouse, R.1    Klein, T.2    Shannon, W.3
  • 22
    • 23944521339 scopus 로고    scopus 로고
    • Consequences of the evolution of the GABA(A) receptor gene family
    • 16075381 1:CAS:528:DC%2BD2MXnslyrurg%3D 10.1007/s10571-005-4004-4
    • MG Darlison I Pahal C Thode 2005 Consequences of the evolution of the GABA(A) receptor gene family Cell Mol Neurobiol 25 607 624 16075381 1:CAS:528:DC%2BD2MXnslyrurg%3D 10.1007/s10571-005-4004-4
    • (2005) Cell Mol Neurobiol , vol.25 , pp. 607-624
    • Darlison, M.G.1    Pahal, I.2    Thode, C.3
  • 23
    • 0035045419 scopus 로고    scopus 로고
    • Ethanol dependence has limited effects on GABA or glutamate transporters in rat brain
    • 11329503 1:CAS:528:DC%2BD3MXjtlGkurk%3D 10.1111/j.1530-0277.2001.tb02257. x
    • LL Devaud 2001 Ethanol dependence has limited effects on GABA or glutamate transporters in rat brain Alcohol Clin Exp Res 25 606 611 11329503 1:CAS:528:DC%2BD3MXjtlGkurk%3D 10.1111/j.1530-0277.2001.tb02257.x
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 606-611
    • Devaud, L.L.1
  • 27
    • 33845468881 scopus 로고    scopus 로고
    • Linkage disequilibrium, haplotype and association studies of a chromosome 4 GABA receptor gene cluster: Candidate gene variants for addictions
    • 16894595 1:CAS:528:DC%2BD2sXmsFalt7w%3D 10.1002/ajmg.b.30349
    • T Drgon C D'Addario GR Uhl 2006 Linkage disequilibrium, haplotype and association studies of a chromosome 4 GABA receptor gene cluster: candidate gene variants for addictions Am J Med Genet B Neuropsychiatr Genet 141B 854 860 16894595 1:CAS:528:DC%2BD2sXmsFalt7w%3D 10.1002/ajmg.b.30349
    • (2006) Am J Med Genet B Neuropsychiatr Genet , vol.141 , pp. 854-860
    • Drgon, T.1    D'Addario, C.2    Uhl, G.R.3
  • 28
    • 0032710004 scopus 로고    scopus 로고
    • Smoking behavior is under the influence of a major quantitative trait locus on human chromosome 5q
    • 10597426
    • R Duggirala L Almasy J Blangero 1999 Smoking behavior is under the influence of a major quantitative trait locus on human chromosome 5q Genet Epidemiol 17 Suppl 1 S139 S144 10597426
    • (1999) Genet Epidemiol , vol.17 , Issue.SUPPL. 1
    • Duggirala, R.1    Almasy, L.2    Blangero, J.3
  • 29
    • 34247847741 scopus 로고    scopus 로고
    • The genetics of alcoholism: Identifying specific genes through family studies
    • 16961766 10.1111/j.1369-1600.2006.00035.x
    • HJ Edenberg T Foroud 2006 The genetics of alcoholism: identifying specific genes through family studies Addict Biol 11 386 396 16961766 10.1111/j.1369-1600.2006.00035.x
    • (2006) Addict Biol , vol.11 , pp. 386-396
    • Edenberg, H.J.1    Foroud, T.2
  • 31
    • 44649088160 scopus 로고    scopus 로고
    • The role of GABA(A) receptors in the development of alcoholism
    • 18440057 1:CAS:528:DC%2BD1cXmvFSjtr0%3D 10.1016/j.pbb.2008.03.007
    • MA Enoch 2008 The role of GABA(A) receptors in the development of alcoholism Pharmacol Biochem Behav 90 95 104 18440057 1:CAS:528: DC%2BD1cXmvFSjtr0%3D 10.1016/j.pbb.2008.03.007
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 95-104
    • Enoch, M.A.1
  • 33
    • 62349083932 scopus 로고    scopus 로고
    • GABRG1 and GABRA2 as independent predictors for alcoholism in two populations
    • 18818659 1:CAS:528:DC%2BD1MXjtFentbs%3D 10.1038/npp.2008.171
    • MA Enoch CA Hodgkinson Q Yuan B Albaugh M Virkkunen D Goldman 2009 GABRG1 and GABRA2 as independent predictors for alcoholism in two populations Neuropsychopharmacology 34 1245 1254 18818659 1:CAS:528:DC%2BD1MXjtFentbs%3D 10.1038/npp.2008.171
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1245-1254
    • Enoch, M.A.1    Hodgkinson, C.A.2    Yuan, Q.3    Albaugh, B.4    Virkkunen, M.5    Goldman, D.6
  • 34
    • 0036741304 scopus 로고    scopus 로고
    • Baclofen antagonizes intravenous self-administration of nicotine in mice and rats
    • 12217945 1:CAS:528:DC%2BD38XntVGqtL4%3D
    • L Fattore G Cossu MC Martellotta W Fratta 2002 Baclofen antagonizes intravenous self-administration of nicotine in mice and rats Alcohol Alcohol 37 495 498 12217945 1:CAS:528:DC%2BD38XntVGqtL4%3D
    • (2002) Alcohol Alcohol , vol.37 , pp. 495-498
    • Fattore, L.1    Cossu, G.2    Martellotta, M.C.3    Fratta, W.4
  • 35
    • 33646708528 scopus 로고    scopus 로고
    • Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis
    • 16395124 10.1097/01.ypg.0000185027.89816.d9
    • C Fehr T Sander A Tadic KP Lenzen I Anghelescu C Klawe N Dahmen LG Schmidt A Szegedi 2006 Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis Psychiatr Genet 16 9 17 16395124 10.1097/01.ypg.0000185027.89816.d9
    • (2006) Psychiatr Genet , vol.16 , pp. 9-17
    • Fehr, C.1    Sander, T.2    Tadic, A.3    Lenzen, K.P.4    Anghelescu, I.5    Klawe, C.6    Dahmen, N.7    Schmidt, L.G.8    Szegedi, A.9
  • 36
    • 44649155740 scopus 로고    scopus 로고
    • Forum: Interactions between gene and environment
    • 18520729 10.1097/YCO.0b013e328306a791
    • J Flint MR Munafo 2008 Forum: interactions between gene and environment Curr Opin Psychiatry 21 315 317 18520729 10.1097/YCO.0b013e328306a791
    • (2008) Curr Opin Psychiatry , vol.21 , pp. 315-317
    • Flint, J.1    Munafo, M.R.2
  • 37
    • 67651119880 scopus 로고    scopus 로고
    • Genetics of alcohol dependence
    • 19533172 1:CAS:528:DC%2BD1MXoslaksbo%3D 10.1007/s00439-009-0701-2
    • J Gelernter HR Kranzler 2009 Genetics of alcohol dependence Hum Genet 126 91 99 19533172 1:CAS:528:DC%2BD1MXoslaksbo%3D 10.1007/s00439-009-0701-2
    • (2009) Hum Genet , vol.126 , pp. 91-99
    • Gelernter, J.1    Kranzler, H.R.2
  • 38
    • 3042806901 scopus 로고    scopus 로고
    • Results of a genomewide linkage scan: Support for chromosomes 9 and 11 loci increasing risk for cigarette smoking
    • 15211640 10.1002/ajmg.b.30019
    • J Gelernter X Liu V Hesselbrock GP Page A Goddard H Zhang 2004 Results of a genomewide linkage scan: support for chromosomes 9 and 11 loci increasing risk for cigarette smoking Am J Med Genet 128B 94 101 15211640 10.1002/ajmg.b.30019
    • (2004) Am J Med Genet , vol.128 , pp. 94-101
    • Gelernter, J.1    Liu, X.2    Hesselbrock, V.3    Page, G.P.4    Goddard, A.5    Zhang, H.6
  • 39
    • 33845202242 scopus 로고    scopus 로고
    • Genomewide linkage scan for nicotine dependence: Identification of a chromosome 5 risk locus
    • 17081504 1:CAS:528:DC%2BD28Xht12kt7rF 10.1016/j.biopsych.2006.08.023
    • J Gelernter C Panhuysen R Weiss K Brady J Poling M Krauthammer L Farrer HR Kranzler 2007 Genomewide linkage scan for nicotine dependence: identification of a chromosome 5 risk locus Biol Psychiatry 61 119 126 17081504 1:CAS:528:DC%2BD28Xht12kt7rF 10.1016/j.biopsych.2006.08.023
    • (2007) Biol Psychiatry , vol.61 , pp. 119-126
    • Gelernter, J.1    Panhuysen, C.2    Weiss, R.3    Brady, K.4    Poling, J.5    Krauthammer, M.6    Farrer, L.7    Kranzler, H.R.8
  • 40
    • 21344469970 scopus 로고    scopus 로고
    • The genetics of addictions: Uncovering the genes
    • 15995696 1:CAS:528:DC%2BD2MXlslWgurc%3D 10.1038/nrg1635
    • D Goldman G Oroszi F Ducci 2005 The genetics of addictions: uncovering the genes Nat Rev Genet 6 521 532 15995696 1:CAS:528:DC%2BD2MXlslWgurc%3D 10.1038/nrg1635
    • (2005) Nat Rev Genet , vol.6 , pp. 521-532
    • Goldman, D.1    Oroszi, G.2    Ducci, F.3
  • 41
    • 0034335360 scopus 로고    scopus 로고
    • Regional variations in the effects of chronic ethanol administration on GABA(A) receptor expression: Potential mechanisms
    • 10871697 1:CAS:528:DC%2BD3cXmvFShsb8%3D 10.1016/S0197-0186(00)00058-9
    • AC Grobin ST Papadeas AL Morrow 2000 Regional variations in the effects of chronic ethanol administration on GABA(A) receptor expression: potential mechanisms Neurochem Int 37 453 461 10871697 1:CAS:528:DC%2BD3cXmvFShsb8%3D 10.1016/S0197-0186(00)00058-9
    • (2000) Neurochem Int , vol.37 , pp. 453-461
    • Grobin, A.C.1    Papadeas, S.T.2    Morrow, A.L.3
  • 42
    • 71349087317 scopus 로고    scopus 로고
    • Meta-analysis of 15 genome-wide linkage scans of smoking behavior
    • 19819424 1:CAS:528:DC%2BD1MXhsFGrsbjF 10.1016/j.biopsych.2009.08.028
    • S Han J Gelernter X Luo BZ Yang 2010 Meta-analysis of 15 genome-wide linkage scans of smoking behavior Biol Psychiatry 67 12 19 19819424 1:CAS:528:DC%2BD1MXhsFGrsbjF 10.1016/j.biopsych.2009.08.028
    • (2010) Biol Psychiatry , vol.67 , pp. 12-19
    • Han, S.1    Gelernter, J.2    Luo, X.3    Yang, B.Z.4
  • 43
    • 42549085591 scopus 로고    scopus 로고
    • Human gamma-aminobutyric acid A receptor alpha2 gene moderates the acute effects of alcohol and brain mRNA expression
    • 18005236 1:CAS:528:DC%2BD1cXnvVOit78%3D 10.1111/j.1601-183X.2007.00369.x
    • HM Haughey LA Ray P Finan R Villanueva M Niculescu KE Hutchison 2008 Human gamma-aminobutyric acid A receptor alpha2 gene moderates the acute effects of alcohol and brain mRNA expression Genes Brain Behav 7 447 454 18005236 1:CAS:528:DC%2BD1cXnvVOit78%3D 10.1111/j.1601-183X.2007.00369.x
    • (2008) Genes Brain Behav , vol.7 , pp. 447-454
    • Haughey, H.M.1    Ray, L.A.2    Finan, P.3    Villanueva, R.4    Niculescu, M.5    Hutchison, K.E.6
  • 45
    • 34147195806 scopus 로고    scopus 로고
    • Overview of the pharmacogenomics of cigarette smoking
    • 17224913 1:CAS:528:DC%2BD2sXjvVaqs7g%3D 10.1038/sj.tpj.6500436
    • MK Ho RF Tyndale 2007 Overview of the pharmacogenomics of cigarette smoking Pharmacogenomics J 7 81 98 17224913 1:CAS:528:DC%2BD2sXjvVaqs7g%3D 10.1038/sj.tpj.6500436
    • (2007) Pharmacogenomics J , vol.7 , pp. 81-98
    • Ho, M.K.1    Tyndale, R.F.2
  • 46
    • 78449313546 scopus 로고    scopus 로고
    • Breaking barriers in the genomics and pharmacogenetics of drug addiction
    • 20981002 1:CAS:528:DC%2BC3cXhsVegu7fE 10.1038/clpt.2010.175
    • MK Ho D Goldman A Heinz J Kaprio MJ Kreek MD Li MR Munafo RF Tyndale 2010 Breaking barriers in the genomics and pharmacogenetics of drug addiction Clin Pharmacol Ther 88 779 791 20981002 1:CAS:528:DC%2BC3cXhsVegu7fE 10.1038/clpt.2010.175
    • (2010) Clin Pharmacol Ther , vol.88 , pp. 779-791
    • Ho, M.K.1    Goldman, D.2    Heinz, A.3    Kaprio, J.4    Kreek, M.J.5    Li, M.D.6    Munafo, M.R.7    Tyndale, R.F.8
  • 47
    • 67649584052 scopus 로고    scopus 로고
    • Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder
    • 19539887 1:CAS:528:DC%2BD1MXhtVelt7fJ 10.1016/j.ajhg.2009.05.011
    • P Holmans EK Green JS Pahwa MA Ferreira SM Purcell P Sklar MJ Owen MC O'Donovan N Craddock 2009 Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder Am J Hum Genet 85 13 24 19539887 1:CAS:528:DC%2BD1MXhtVelt7fJ 10.1016/j.ajhg.2009.05.011
    • (2009) Am J Hum Genet , vol.85 , pp. 13-24
    • Holmans, P.1    Green, E.K.2    Pahwa, J.S.3    Ferreira, M.A.4    Purcell, S.M.5    Sklar, P.6    Owen, M.J.7    O'Donovan, M.C.8    Craddock, N.9
  • 48
    • 0026564251 scopus 로고
    • Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to distal 5q by linkage analysis
    • 1330891 1:CAS:528:DyaK3sXhs1ahs7g%3D 10.1016/S0888-7543(05)80178-8
    • KJ Johnson T Sander AA Hicks A van Marle D Janz MJ Mullan BP Riley MG Darlison 1992 Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to distal 5q by linkage analysis Genomics 14 745 748 1330891 1:CAS:528:DyaK3sXhs1ahs7g%3D 10.1016/S0888-7543(05)80178-8
    • (1992) Genomics , vol.14 , pp. 745-748
    • Johnson, K.J.1    Sander, T.2    Hicks, A.A.3    Van Marle, A.4    Janz, D.5    Mullan, M.J.6    Riley, B.P.7    Darlison, M.G.8
  • 49
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • 11060023 1:CAS:528:DC%2BD3cXovFaiurk%3D 10.1093/emboj/19.21.5720
    • Y Kabeya N Mizushima T Ueno A Yamamoto T Kirisako T Noda E Kominami Y Ohsumi T Yoshimori 2000 LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing EMBO J 19 5720 5728 11060023 1:CAS:528:DC%2BD3cXovFaiurk%3D 10.1093/emboj/19.21.5720
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6    Kominami, E.7    Ohsumi, Y.8    Yoshimori, T.9
  • 50
    • 33846458990 scopus 로고    scopus 로고
    • Presynaptic delta opioid receptors regulate ethanol actions in central amygdala
    • 17114568 1:CAS:528:DC%2BD2sXhs1WrsLw%3D 10.1124/jpet.106.112722
    • MH Kang-Park BL Kieffer AJ Roberts GR Siggins SD Moore 2007 Presynaptic delta opioid receptors regulate ethanol actions in central amygdala J Pharmacol Exp Ther 320 917 925 17114568 1:CAS:528:DC%2BD2sXhs1WrsLw%3D 10.1124/jpet.106.112722
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 917-925
    • Kang-Park, M.H.1    Kieffer, B.L.2    Roberts, A.J.3    Siggins, G.R.4    Moore, S.D.5
  • 52
    • 78649934510 scopus 로고    scopus 로고
    • Ethanol-enhanced GABA release: A focus on G protein-coupled receptors
    • 20837058 1:CAS:528:DC%2BC3cXhsFCrtbbK 10.1016/j.brainresrev.2010.09.003
    • MK Kelm HE Criswell GR Breese 2011 Ethanol-enhanced GABA release: a focus on G protein-coupled receptors Brain Res Rev 65 113 123 20837058 1:CAS:528:DC%2BC3cXhsFCrtbbK 10.1016/j.brainresrev.2010.09.003
    • (2011) Brain Res Rev , vol.65 , pp. 113-123
    • Kelm, M.K.1    Criswell, H.E.2    Breese, G.R.3
  • 53
    • 79956137330 scopus 로고    scopus 로고
    • Zebrafish for the study of the biological effects of nicotine
    • 10.1093/ntr/ntr010 1:CAS:528:DC%2BC3MXlsV2ls7c%3D
    • EW Klee JO Ebbert H Schneider RD Hurt SC Ekker 2010 Zebrafish for the study of the biological effects of nicotine Nicotine Tob Res 13 301 312 10.1093/ntr/ntr010 1:CAS:528:DC%2BC3MXlsV2ls7c%3D
    • (2010) Nicotine Tob Res , vol.13 , pp. 301-312
    • Klee, E.W.1    Ebbert, J.O.2    Schneider, H.3    Hurt, R.D.4    Ekker, S.C.5
  • 54
    • 36849038927 scopus 로고    scopus 로고
    • Approach to the genetics of alcoholism: A review based on pathophysiology
    • 17669369 10.1016/j.bcp.2007.06.021 1:CAS:528:DC%2BD2sXhsVCksLjN
    • MD Kohnke 2008 Approach to the genetics of alcoholism: a review based on pathophysiology Biochem Pharmacol 75 160 177 17669369 10.1016/j.bcp.2007.06.021 1:CAS:528:DC%2BD2sXhsVCksLjN
    • (2008) Biochem Pharmacol , vol.75 , pp. 160-177
    • Kohnke, M.D.1
  • 55
    • 33748316516 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid type A receptors and alcoholism: Intoxication, dependence, vulnerability, and treatment
    • 16952998 1:CAS:528:DC%2BD28XhtVamtr7M 10.1001/archpsyc.63.9.957
    • JH Krystal J Staley G Mason IL Petrakis J Kaufman RA Harris J Gelernter J Lappalainen 2006 Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment Arch Gen Psychiatry 63 957 968 16952998 1:CAS:528:DC%2BD28XhtVamtr7M 10.1001/archpsyc.63.9.957
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 957-968
    • Krystal, J.H.1    Staley, J.2    Mason, G.3    Petrakis, I.L.4    Kaufman, J.5    Harris, R.A.6    Gelernter, J.7    Lappalainen, J.8
  • 56
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • 7581446 1:CAS:528:DyaK2MXptlSjs74%3D 10.1038/ng1195-241
    • E Lander L Kruglyak 1995 Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results Nat Genet 11 241 247 7581446 1:CAS:528:DyaK2MXptlSjs74%3D 10.1038/ng1195-241
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 57
    • 0032126632 scopus 로고    scopus 로고
    • Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole
    • 9649430 1:CAS:528:DyaK1cXkslSjtrc%3D 10.1093/emboj/17.13.3597
    • T Lang E Schaeffeler D Bernreuther M Bredschneider DH Wolf M Thumm 1998 Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole EMBO J 17 3597 3607 9649430 1:CAS:528:DyaK1cXkslSjtrc%3D 10.1093/emboj/17.13.3597
    • (1998) EMBO J , vol.17 , pp. 3597-3607
    • Lang, T.1    Schaeffeler, E.2    Bernreuther, D.3    Bredschneider, M.4    Wolf, D.H.5    Thumm, M.6
  • 60
    • 10644254853 scopus 로고    scopus 로고
    • GABAA receptor-associated protein traffics GABAA receptors to the plasma membrane in neurons
    • 15601949 1:CAS:528:DC%2BD2MXjtVajsQ%3D%3D 10.1523/JNEUROSCI.3355-04.2004
    • TA Leil ZW Chen CS Chang RW Olsen 2004 GABAA receptor-associated protein traffics GABAA receptors to the plasma membrane in neurons J Neurosci 24 11429 11438 15601949 1:CAS:528:DC%2BD2MXjtVajsQ%3D%3D 10.1523/JNEUROSCI.3355-04.2004
    • (2004) J Neurosci , vol.24 , pp. 11429-11438
    • Leil, T.A.1    Chen, Z.W.2    Chang, C.S.3    Olsen, R.W.4
  • 61
    • 36849039962 scopus 로고    scopus 로고
    • Genetics of nicotine dependence and pharmacotherapy
    • 17888884 1:CAS:528:DC%2BD2sXhsVCksLjI 10.1016/j.bcp.2007.08.018
    • CN Lessov-Schlaggar ML Pergadia TV Khroyan GE Swan 2008 Genetics of nicotine dependence and pharmacotherapy Biochem Pharmacol 75 178 195 17888884 1:CAS:528:DC%2BD2sXhsVCksLjI 10.1016/j.bcp.2007.08.018
    • (2008) Biochem Pharmacol , vol.75 , pp. 178-195
    • Lessov-Schlaggar, C.N.1    Pergadia, M.L.2    Khroyan, T.V.3    Swan, G.E.4
  • 62
    • 33645559825 scopus 로고    scopus 로고
    • The genetics of nicotine dependence
    • 16539894 1:CAS:528:DC%2BD28XhtFKntr3E 10.1007/s11920-006-0016-0
    • MD Li 2006 The genetics of nicotine dependence Curr Psychiatry Rep 8 158 164 16539894 1:CAS:528:DC%2BD28XhtFKntr3E 10.1007/s11920-006-0016-0
    • (2006) Curr Psychiatry Rep , vol.8 , pp. 158-164
    • Li, M.D.1
  • 63
    • 39549102848 scopus 로고    scopus 로고
    • Identifying susceptibility loci for nicotine dependence: 2008 update based on recent genome-wide linkage analyses
    • 18205015 1:CAS:528:DC%2BD1cXitVSrurg%3D 10.1007/s00439-008-0473-0
    • MD Li 2008 Identifying susceptibility loci for nicotine dependence: 2008 update based on recent genome-wide linkage analyses Hum Genet 123 119 131 18205015 1:CAS:528:DC%2BD1cXitVSrurg%3D 10.1007/s00439-008-0473-0
    • (2008) Hum Genet , vol.123 , pp. 119-131
    • Li, M.D.1
  • 64
    • 84862700979 scopus 로고    scopus 로고
    • Grand challenges and opportunities for molecular psychiatry research: A perspective
    • 21423414
    • MD Li 2010 Grand challenges and opportunities for molecular psychiatry research: a perspective Front Psychiatry 1 2 21423414
    • (2010) Front Psychiatry , vol.1 , pp. 2
    • Li, M.D.1
  • 65
    • 62549148987 scopus 로고    scopus 로고
    • New insights into the genetics of addiction
    • 19238175 1:CAS:528:DC%2BD1MXjt1Ckurc%3D 10.1038/nrg2536
    • MD Li M Burmeister 2009 New insights into the genetics of addiction Nat Rev Genet 10 225 231 19238175 1:CAS:528:DC%2BD1MXjt1Ckurc%3D 10.1038/nrg2536
    • (2009) Nat Rev Genet , vol.10 , pp. 225-231
    • Li, M.D.1    Burmeister, M.2
  • 66
    • 0037221274 scopus 로고    scopus 로고
    • A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins
    • 12492752 10.1046/j.1360-0443.2003.00295.x
    • MD Li R Cheng JZ Ma GE Swan 2003 A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins Addiction 98 23 31 12492752 10.1046/j.1360-0443.2003.00295.x
    • (2003) Addiction , vol.98 , pp. 23-31
    • Li, M.D.1    Cheng, R.2    Ma, J.Z.3    Swan, G.E.4
  • 67
    • 84872249295 scopus 로고    scopus 로고
    • A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population
    • 14975171 10.1186/1471-2156-4-S1-S103
    • MD Li JZ Ma R Cheng RT Dupont NJ Williams KM Crews TJ Payne RC Elston 2003 A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population BMC Genet 4 Suppl 1 S103 14975171 10.1186/1471-2156-4-S1- S103
    • (2003) BMC Genet , vol.4 , Issue.SUPPL. 1 , pp. 103
    • Li, M.D.1    Ma, J.Z.2    Cheng, R.3    Dupont, R.T.4    Williams, N.J.5    Crews, K.M.6    Payne, T.J.7    Elston, R.C.8
  • 68
    • 9744285770 scopus 로고    scopus 로고
    • Time-dependent changes in transcriptional profiles within five rat brain regions in response to nicotine treatment
    • 15582156 1:CAS:528:DC%2BD2cXhtVCktLnI 10.1016/j.molbrainres.2004.09.009
    • MD Li JK Kane J Wang JZ Ma 2004 Time-dependent changes in transcriptional profiles within five rat brain regions in response to nicotine treatment Brain Res Mol Brain Res 132 168 180 15582156 1:CAS:528:DC%2BD2cXhtVCktLnI 10.1016/j.molbrainres.2004.09.009
    • (2004) Brain Res Mol Brain Res , vol.132 , pp. 168-180
    • Li, M.D.1    Kane, J.K.2    Wang, J.3    Ma, J.Z.4
  • 69
    • 33749033629 scopus 로고    scopus 로고
    • A genomewide search finds major susceptibility Loci for nicotine dependence on chromosome 10 in African Americans
    • 16960812 1:CAS:528:DC%2BD28XhtVChurvN 10.1086/508208
    • MD Li TJ Payne JZ Ma XY Lou D Zhang RT Dupont KM Crews G Somes NJ Williams RC Elston 2006 A genomewide search finds major susceptibility Loci for nicotine dependence on chromosome 10 in African Americans Am J Hum Genet 79 745 751 16960812 1:CAS:528:DC%2BD28XhtVChurvN 10.1086/508208
    • (2006) Am J Hum Genet , vol.79 , pp. 745-751
    • Li, M.D.1    Payne, T.J.2    Ma, J.Z.3    Lou, X.Y.4    Zhang, D.5    Dupont, R.T.6    Crews, K.M.7    Somes, G.8    Williams, N.J.9    Elston, R.C.10
  • 70
    • 34247543567 scopus 로고    scopus 로고
    • Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence
    • 17179996 1:CAS:528:DC%2BD28Xhtlaktr3L 10.1038/sj.mp.4001890
    • MD Li D Sun XY Lou J Beuten TJ Payne JZ Ma 2007 Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence Mol Psychiatry 12 462 473 17179996 1:CAS:528:DC%2BD28Xhtlaktr3L 10.1038/sj.mp.4001890
    • (2007) Mol Psychiatry , vol.12 , pp. 462-473
    • Li, M.D.1    Sun, D.2    Lou, X.Y.3    Beuten, J.4    Payne, T.J.5    Ma, J.Z.6
  • 71
    • 40849105029 scopus 로고    scopus 로고
    • Genome-wide linkage scan for nicotine dependence in European Americans and its converging results with African Americans in the Mid-South Tobacco Family sample
    • 17579606 1:CAS:528:DC%2BD1cXjtlyrsrk%3D 10.1038/sj.mp.4002038
    • MD Li JZ Ma TJ Payne XY Lou D Zhang RT Dupont RC Elston 2008 Genome-wide linkage scan for nicotine dependence in European Americans and its converging results with African Americans in the Mid-South Tobacco Family sample Mol Psychiatry 13 407 416 17579606 1:CAS:528:DC%2BD1cXjtlyrsrk%3D 10.1038/sj.mp.4002038
    • (2008) Mol Psychiatry , vol.13 , pp. 407-416
    • Li, M.D.1    Ma, J.Z.2    Payne, T.J.3    Lou, X.Y.4    Zhang, D.5    Dupont, R.T.6    Elston, R.C.7
  • 72
    • 70349466340 scopus 로고    scopus 로고
    • Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations
    • 19763258 10.1371/journal.pone.0007055 1:CAS:528:DC%2BD1MXhtFymt7zM
    • MD Li JE Mangold C Seneviratne GB Chen JZ Ma XY Lou TJ Payne 2009 Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations PLoS One 4 e7055 19763258 10.1371/journal.pone.0007055 1:CAS:528:DC%2BD1MXhtFymt7zM
    • (2009) PLoS One , vol.4 , pp. 7055
    • Li, M.D.1    Mangold, J.E.2    Seneviratne, C.3    Chen, G.B.4    Ma, J.Z.5    Lou, X.Y.6    Payne, T.J.7
  • 73
    • 52149091915 scopus 로고    scopus 로고
    • The role of GABRA2 in alcohol dependence, smoking, and illicit drug use in an Australian population sample
    • 18727688 1:CAS:528:DC%2BD1cXht1KqsLfJ 10.1111/j.1530-0277.2008.00768.x
    • PA Lind S Macgregor A Agrawal GW Montgomery AC Heath NG Martin JB Whitfield 2008 The role of GABRA2 in alcohol dependence, smoking, and illicit drug use in an Australian population sample Alcohol Clin Exp Res 32 1721 1731 18727688 1:CAS:528:DC%2BD1cXht1KqsLfJ 10.1111/j.1530-0277.2008.00768.x
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 1721-1731
    • Lind, P.A.1    MacGregor, S.2    Agrawal, A.3    Montgomery, G.W.4    Heath, A.C.5    Martin, N.G.6    Whitfield, J.B.7
  • 74
    • 0033220401 scopus 로고    scopus 로고
    • Association between variants at the GABAAbeta2, GABAAalpha6 and GABAAgamma2 gene cluster and alcohol dependence in a Scottish population
    • 10578235 1:CAS:528:DC%2BD3cXlvVeqtr8%3D 10.1038/sj.mp.4000554
    • EW Loh I Smith R Murray M McLaughlin S McNulty D Ball 1999 Association between variants at the GABAAbeta2, GABAAalpha6 and GABAAgamma2 gene cluster and alcohol dependence in a Scottish population Mol Psychiatry 4 539 544 10578235 1:CAS:528:DC%2BD3cXlvVeqtr8%3D 10.1038/sj.mp.4000554
    • (1999) Mol Psychiatry , vol.4 , pp. 539-544
    • Loh, E.W.1    Smith, I.2    Murray, R.3    McLaughlin, M.4    McNulty, S.5    Ball, D.6
  • 75
    • 0032496340 scopus 로고    scopus 로고
    • Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population
    • 9603607 1:STN:280:DyaK1c3msVOksg%3D%3D 10.1002/(SICI)1096-8628(19980508) 81:3<216::AID-AJMG2>3.0.CO;2-U
    • JC Long WC Knowler RL Hanson RW Robin M Urbanek E Moore PH Bennett D Goldman 1998 Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population Am J Med Genet 81 216 221 9603607 1:STN:280:DyaK1c3msVOksg%3D%3D 10.1002/(SICI)1096- 8628(19980508)81:3<216::AID-AJMG2>3.0.CO;2-U
    • (1998) Am J Med Genet , vol.81 , pp. 216-221
    • Long, J.C.1    Knowler, W.C.2    Hanson, R.L.3    Robin, R.W.4    Urbanek, M.5    Moore, E.6    Bennett, P.H.7    Goldman, D.8
  • 76
    • 34250821108 scopus 로고    scopus 로고
    • A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence
    • 17503330 1:CAS:528:DC%2BD2sXmtFGmsbk%3D 10.1086/518312
    • XY Lou GB Chen L Yan JZ Ma J Zhu RC Elston MD Li 2007 A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence Am J Hum Genet 80 1125 1137 17503330 1:CAS:528:DC%2BD2sXmtFGmsbk%3D 10.1086/518312
    • (2007) Am J Hum Genet , vol.80 , pp. 1125-1137
    • Lou, X.Y.1    Chen, G.B.2    Yan, L.3    Ma, J.Z.4    Zhu, J.5    Elston, R.C.6    Li, M.D.7
  • 77
    • 33846580530 scopus 로고    scopus 로고
    • Fine mapping of a linkage region on chromosome 17p13 reveals that GABARAP and DLG4 are associated with vulnerability to nicotine dependence in European-Americans
    • 17164261 1:CAS:528:DC%2BD2sXhtVKktrg%3D 10.1093/hmg/ddl450
    • XY Lou JZ Ma D Sun TJ Payne MD Li 2007 Fine mapping of a linkage region on chromosome 17p13 reveals that GABARAP and DLG4 are associated with vulnerability to nicotine dependence in European-Americans Hum Mol Genet 16 142 153 17164261 1:CAS:528:DC%2BD2sXhtVKktrg%3D 10.1093/hmg/ddl450
    • (2007) Hum Mol Genet , vol.16 , pp. 142-153
    • Lou, X.Y.1    Ma, J.Z.2    Sun, D.3    Payne, T.J.4    Li, M.D.5
  • 78
    • 53049102597 scopus 로고    scopus 로고
    • A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies
    • 18834969 1:CAS:528:DC%2BD1cXht1Omtb3P 10.1016/j.ajhg.2008.09.001
    • XY Lou GB Chen L Yan JZ Ma JE Mangold J Zhu RC Elston MD Li 2008 A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies Am J Hum Genet 83 457 467 18834969 1:CAS:528: DC%2BD1cXht1Omtb3P 10.1016/j.ajhg.2008.09.001
    • (2008) Am J Hum Genet , vol.83 , pp. 457-467
    • Lou, X.Y.1    Chen, G.B.2    Yan, L.3    Ma, J.Z.4    Mangold, J.E.5    Zhu, J.6    Elston, R.C.7    Li, M.D.8
  • 80
    • 70350765125 scopus 로고    scopus 로고
    • Role of the GABA(B) receptor in alcohol-seeking and drinking behavior
    • 19913200 1:CAS:528:DC%2BD1MXhsVaisrrL 10.1016/j.alcohol.2009.09.030
    • P Maccioni G Colombo 2009 Role of the GABA(B) receptor in alcohol-seeking and drinking behavior Alcohol 43 555 558 19913200 1:CAS:528:DC%2BD1MXhsVaisrrL 10.1016/j.alcohol.2009.09.030
    • (2009) Alcohol , vol.43 , pp. 555-558
    • MacCioni, P.1    Colombo, G.2
  • 81
    • 0035084663 scopus 로고    scopus 로고
    • A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation
    • 11230170 1:CAS:528:DC%2BD3MXhvVOntrg%3D 10.1101/gr.172901
    • MR Nelson SL Kardia RE Ferrell CF Sing 2001 A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation Genome Res 11 458 470 11230170 1:CAS:528:DC%2BD3MXhvVOntrg%3D 10.1101/gr.172901
    • (2001) Genome Res , vol.11 , pp. 458-470
    • Nelson, M.R.1    Kardia, S.L.2    Ferrell, R.E.3    Sing, C.F.4
  • 82
    • 1542377428 scopus 로고    scopus 로고
    • Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors
    • 15001778 1:CAS:528:DC%2BD2cXhslCgsLo%3D 10.1126/science.1092550
    • Z Nie P Schweitzer AJ Roberts SG Madamba SD Moore GR Siggins 2004 Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors Science 303 1512 1514 15001778 1:CAS:528:DC%2BD2cXhslCgsLo%3D 10.1126/science.1092550
    • (2004) Science , vol.303 , pp. 1512-1514
    • Nie, Z.1    Schweitzer, P.2    Roberts, A.J.3    Madamba, S.G.4    Moore, S.D.5    Siggins, G.R.6
  • 83
    • 65549137542 scopus 로고    scopus 로고
    • Presynaptic CRF1 receptors mediate the ethanol enhancement of GABAergic transmission in the mouse central amygdala
    • 1:CAS:528:DC%2BD1MXlsFygsbw%3D 10.1100/tsw.2009.1
    • Z Nie EP Zorrilla SG Madamba KC Rice M Roberto GR Siggins 2009 Presynaptic CRF1 receptors mediate the ethanol enhancement of GABAergic transmission in the mouse central amygdala Sci World J 9 68 85 1:CAS:528:DC%2BD1MXlsFygsbw%3D 10.1100/tsw.2009.1
    • (2009) Sci World J , vol.9 , pp. 68-85
    • Nie, Z.1    Zorrilla, E.P.2    Madamba, S.G.3    Rice, K.C.4    Roberto, M.5    Siggins, G.R.6
  • 84
    • 0027395256 scopus 로고
    • Identification and characterization of an early estrogen-regulated RNA in cultured guinea-pig endometrial cells
    • 8495796 1:CAS:528:DyaK3sXntlyksw%3D%3D 10.1016/0303-7207(93)90161-C
    • I Pellerin C Vuillermoz M Jouvenot C Ordener M Royez GL Adessi 1993 Identification and characterization of an early estrogen-regulated RNA in cultured guinea-pig endometrial cells Mol Cell Endocrinol 90 R17 R21 8495796 1:CAS:528:DyaK3sXntlyksw%3D%3D 10.1016/0303-7207(93)90161-C
    • (1993) Mol Cell Endocrinol , vol.90
    • Pellerin, I.1    Vuillermoz, C.2    Jouvenot, M.3    Ordener, C.4    Royez, M.5    Adessi, G.L.6
  • 85
    • 0030985420 scopus 로고    scopus 로고
    • Effects of chronic ethanol exposure on GABA receptors and GABAB receptor modulation of 3H-GABA release in the hippocampus
    • 9309316 1:CAS:528:DyaK2sXmsFWlurk%3D
    • J Peris B Eppler M Hu DW Walker BE Hunter K Mason KJ Anderson 1997 Effects of chronic ethanol exposure on GABA receptors and GABAB receptor modulation of 3H-GABA release in the hippocampus Alcohol Clin Exp Res 21 1047 1052 9309316 1:CAS:528:DyaK2sXmsFWlurk%3D
    • (1997) Alcohol Clin Exp Res , vol.21 , pp. 1047-1052
    • Peris, J.1    Eppler, B.2    Hu, M.3    Walker, D.W.4    Hunter, B.E.5    Mason, K.6    Anderson, K.J.7
  • 89
    • 11844262032 scopus 로고    scopus 로고
    • Haplotype-based localization of an alcohol dependence gene to the 5q34 {gamma}-aminobutyric acid type A gene cluster
    • 15630072 1:CAS:528:DC%2BD2MXht1Kns7g%3D 10.1001/archpsyc.62.1.47
    • M Radel RL Vallejo N Iwata R Aragon JC Long M Virkkunen D Goldman 2005 Haplotype-based localization of an alcohol dependence gene to the 5q34 {gamma}-aminobutyric acid type A gene cluster Arch Gen Psychiatry 62 47 55 15630072 1:CAS:528:DC%2BD2MXht1Kns7g%3D 10.1001/archpsyc.62.1.47
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 47-55
    • Radel, M.1    Vallejo, R.L.2    Iwata, N.3    Aragon, R.4    Long, J.C.5    Virkkunen, M.6    Goldman, D.7
  • 91
    • 0034973569 scopus 로고    scopus 로고
    • Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
    • 11404819 1:CAS:528:DC%2BD3MXls1emt7k%3D 10.1086/321276
    • MD Ritchie LW Hahn N Roodi LR Bailey WD Dupont FF Parl JH Moore 2001 Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer Am J Hum Genet 69 138 147 11404819 1:CAS:528:DC%2BD3MXls1emt7k%3D 10.1086/321276
    • (2001) Am J Hum Genet , vol.69 , pp. 138-147
    • Ritchie, M.D.1    Hahn, L.W.2    Roodi, N.3    Bailey, L.R.4    Dupont, W.D.5    Parl, F.F.6    Moore, J.H.7
  • 92
    • 77954758418 scopus 로고    scopus 로고
    • The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala
    • 20463657 1:CAS:528:DC%2BC3cXovFKmsb4%3D 10.1038/npp.2010.70
    • M Roberto M Cruz M Bajo GR Siggins LH Parsons P Schweitzer 2010 The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala Neuropsychopharmacology 35 1962 1972 20463657 1:CAS:528:DC%2BC3cXovFKmsb4%3D 10.1038/npp.2010.70
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1962-1972
    • Roberto, M.1    Cruz, M.2    Bajo, M.3    Siggins, G.R.4    Parsons, L.H.5    Schweitzer, P.6
  • 95
    • 0001417555 scopus 로고    scopus 로고
    • GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28
    • 10747018 1:CAS:528:DC%2BD3cXislymtrk%3D 10.1093/emboj/19.7.1494
    • Y Sagiv A Legesse-Miller A Porat Z Elazar 2000 GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28 EMBO J 19 1494 1504 10747018 1:CAS:528:DC%2BD3cXislymtrk%3D 10.1093/emboj/19.7.1494
    • (2000) EMBO J , vol.19 , pp. 1494-1504
    • Sagiv, Y.1    Legesse-Miller, A.2    Porat, A.3    Elazar, Z.4
  • 96
    • 0032741414 scopus 로고    scopus 로고
    • Association analysis of exonic variants of the gene encoding the GABAB receptor and alcohol dependence
    • 10412185 1:STN:280:DyaK1MzktVKrsA%3D%3D 10.1097/00041444-199906000-00004
    • T Sander J Samochowiec M Ladehoff M Smolka C Peters O Riess H Rommelspacher LG Schmidt 1999 Association analysis of exonic variants of the gene encoding the GABAB receptor and alcohol dependence Psychiatr Genet 9 69 73 10412185 1:STN:280:DyaK1MzktVKrsA%3D%3D 10.1097/00041444-199906000-00004
    • (1999) Psychiatr Genet , vol.9 , pp. 69-73
    • Sander, T.1    Samochowiec, J.2    Ladehoff, M.3    Smolka, M.4    Peters, C.5    Riess, O.6    Rommelspacher, H.7    Schmidt, L.G.8
  • 98
    • 63049116476 scopus 로고    scopus 로고
    • Differential effects of GABAB autoreceptor activation on ethanol potentiation of local and lateral paracapsular GABAergic synapses in the rat basolateral amygdala
    • 19371578 1:CAS:528:DC%2BD1MXkt1Sitrg%3D 10.1016/j.neuropharm.2009.01.013
    • Y Silberman OJ Ariwodola JL Weiner 2009 Differential effects of GABAB autoreceptor activation on ethanol potentiation of local and lateral paracapsular GABAergic synapses in the rat basolateral amygdala Neuropharmacology 56 886 895 19371578 1:CAS:528:DC%2BD1MXkt1Sitrg%3D 10.1016/j.neuropharm.2009.01.013
    • (2009) Neuropharmacology , vol.56 , pp. 886-895
    • Silberman, Y.1    Ariwodola, O.J.2    Weiner, J.L.3
  • 100
    • 0033301678 scopus 로고    scopus 로고
    • The genetic epidemiology of smoking
    • discussion S69-70
    • Sullivan PF, Kendler KS (1999) The genetic epidemiology of smoking. Nicotine Tob Res 1(Suppl 2):S51-57. (discussion S69-70)
    • (1999) Nicotine Tob Res , vol.1 , Issue.SUPPL. 2
    • Sullivan, P.F.1    Kendler, K.S.2
  • 103
    • 8744243995 scopus 로고    scopus 로고
    • GABRA6 gene polymorphism and an attenuated stress response
    • 15197399 1:CAS:528:DC%2BD2cXovVGit7w%3D 10.1038/sj.mp.4001535
    • M Uhart ME McCaul LM Oswald L Choi GS Wand 2004 GABRA6 gene polymorphism and an attenuated stress response Mol Psychiatry 9 998 1006 15197399 1:CAS:528:DC%2BD2cXovVGit7w%3D 10.1038/sj.mp.4001535
    • (2004) Mol Psychiatry , vol.9 , pp. 998-1006
    • Uhart, M.1    McCaul, M.E.2    Oswald, L.M.3    Choi, L.4    Wand, G.S.5
  • 104
    • 65549083036 scopus 로고    scopus 로고
    • Gene-environment interactions and alcohol use and dependence: Current status and future challenges
    • 19466917 10.1111/j.1360-0443.2009.02563.x
    • CS van der Zwaluw RC Engels 2009 Gene-environment interactions and alcohol use and dependence: current status and future challenges Addiction 104 907 914 19466917 10.1111/j.1360-0443.2009.02563.x
    • (2009) Addiction , vol.104 , pp. 907-914
    • Van Der Zwaluw, C.S.1    Engels, R.C.2
  • 105
    • 84860196748 scopus 로고    scopus 로고
    • Impulsiveness and insula activation during reward anticipation are associated with genetic variants in GABRA2 in a family sample enriched for alcoholism
    • Epub ahead of print
    • Villafuerte S, Heitzeg MM, Foley S, Wendy Yau WY, Majczenko K, Zubieta JK, Zucker RA, Burmeister M (2011) Impulsiveness and insula activation during reward anticipation are associated with genetic variants in GABRA2 in a family sample enriched for alcoholism. Mol Psychiatry [Epub ahead of print]
    • (2011) Mol Psychiatry
    • Villafuerte, S.1    Heitzeg, M.M.2    Foley, S.3    Wendy Yau, W.Y.4    Majczenko, K.5    Zubieta, J.K.6    Zucker, R.A.7    Burmeister, M.8
  • 106
    • 77955044675 scopus 로고    scopus 로고
    • GABAB receptors in reward processes
    • 20655488 1:CAS:528:DC%2BC3cXhsFOgurrP 10.1016/S1054-3589(10)58013-X
    • S Vlachou A Markou 2010 GABAB receptors in reward processes Adv Pharmacol 58 315 371 20655488 1:CAS:528:DC%2BC3cXhsFOgurrP 10.1016/S1054-3589(10)58013-X
    • (2010) Adv Pharmacol , vol.58 , pp. 315-371
    • Vlachou, S.1    Markou, A.2
  • 107
    • 75749124555 scopus 로고    scopus 로고
    • Common and unique biological pathways associated with smoking initiation/progression, nicotine dependence, and smoking cessation
    • 19890259 1:CAS:528:DC%2BC3cXhtlCrurg%3D 10.1038/npp.2009.178
    • J Wang MD Li 2010 Common and unique biological pathways associated with smoking initiation/progression, nicotine dependence, and smoking cessation Neuropsychopharmacology 35 702 719 19890259 1:CAS:528:DC%2BC3cXhtlCrurg%3D 10.1038/npp.2009.178
    • (2010) Neuropsychopharmacology , vol.35 , pp. 702-719
    • Wang, J.1    Li, M.D.2
  • 108
    • 0033531225 scopus 로고    scopus 로고
    • GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton
    • 9892355 1:CAS:528:DyaK1MXns1WrsQ%3D%3D 10.1038/16264
    • H Wang FK Bedford NJ Brandon SJ Moss RW Olsen 1999 GABA(A)-receptor- associated protein links GABA(A) receptors and the cytoskeleton Nature 397 69 72 9892355 1:CAS:528:DyaK1MXns1WrsQ%3D%3D 10.1038/16264
    • (1999) Nature , vol.397 , pp. 69-72
    • Wang, H.1    Bedford, F.K.2    Brandon, N.J.3    Moss, S.J.4    Olsen, R.W.5
  • 109
    • 20744456329 scopus 로고    scopus 로고
    • Mapping and verification of susceptibility loci for smoking quantity using permutation linkage analysis
    • 15724146 10.1038/sj.tpj.6500304 1:CAS:528:DC%2BD2MXktlCmt7s%3D
    • D Wang JZ Ma MD Li 2005 Mapping and verification of susceptibility loci for smoking quantity using permutation linkage analysis Pharmacogenomics J 5 166 172 15724146 10.1038/sj.tpj.6500304 1:CAS:528:DC%2BD2MXktlCmt7s%3D
    • (2005) Pharmacogenomics J , vol.5 , pp. 166-172
    • Wang, D.1    Ma, J.Z.2    Li, M.D.3
  • 110
    • 36249029788 scopus 로고    scopus 로고
    • Pathway-based approaches for analysis of genomewide association studies
    • 17966091 1:CAS:528:DC%2BD2sXhtl2ju7%2FM 10.1086/522374
    • K Wang M Li M Bucan 2007 Pathway-based approaches for analysis of genomewide association studies Am J Hum Genet 81 1278 1283 17966091 1:CAS:528:DC%2BD2sXhtl2ju7%2FM 10.1086/522374
    • (2007) Am J Hum Genet , vol.81 , pp. 1278-1283
    • Wang, K.1    Li, M.2    Bucan, M.3
  • 111
    • 0003731907 scopus 로고    scopus 로고
    • WHO World Health Organization
    • WHO (2002) The World Health Report 2002. World Health Organization
    • (2002) The World Health Report 2002
  • 112
    • 77955894071 scopus 로고    scopus 로고
    • METAL: Fast and efficient meta-analysis of genomewide association scans
    • 20616382 1:CAS:528:DC%2BC3cXhtVGru73F 10.1093/bioinformatics/btq340
    • CJ Willer Y Li GR Abecasis 2010 METAL: fast and efficient meta-analysis of genomewide association scans Bioinformatics 26 2190 2191 20616382 1:CAS:528:DC%2BC3cXhtVGru73F 10.1093/bioinformatics/btq340
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 113
    • 14344260210 scopus 로고    scopus 로고
    • Differential GABAB receptor modulation of ethanol effects on GABA(A) synaptic activity in hippocampal CA1 neurons
    • 15615867 1:CAS:528:DC%2BD2MXitVOhu7k%3D 10.1124/jpet.104.075663
    • PH Wu W Poelchen WR Proctor 2005 Differential GABAB receptor modulation of ethanol effects on GABA(A) synaptic activity in hippocampal CA1 neurons J Pharmacol Exp Ther 312 1082 1089 15615867 1:CAS:528:DC%2BD2MXitVOhu7k%3D 10.1124/jpet.104.075663
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 1082-1089
    • Wu, P.H.1    Poelchen, W.2    Proctor, W.R.3
  • 114
    • 0032708084 scopus 로고    scopus 로고
    • Genome search for alcohol dependence using the weighted pairwise correlation linkage method: Interesting findings on chromosome 4
    • 10597473
    • A Zinn-Justin L Abel 1999 Genome search for alcohol dependence using the weighted pairwise correlation linkage method: interesting findings on chromosome 4 Genet Epidemiol 17 Suppl 1 S421 S426 10597473
    • (1999) Genet Epidemiol , vol.17 , Issue.SUPPL. 1
    • Zinn-Justin, A.1    Abel, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.