메뉴 건너뛰기




Volumn 17, Issue 13, 1998, Pages 3597-3607

Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole

Author keywords

Aut2p; Aut7p; Autophagocytosis; Autophagosomes; LC3; Microtubules

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN; TUBULIN;

EID: 0032126632     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.13.3597     Document Type: Article
Times cited : (233)

References (38)
  • 1
    • 0026787605 scopus 로고
    • Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles
    • Aplin, A., Jasionowski, T., Tuttle, D.L., Lenk, S.E. and Dunn, W.J. (1992) Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles. J. Cell Physiol., 152, 458-466.
    • (1992) J. Cell Physiol. , vol.152 , pp. 458-466
    • Aplin, A.1    Jasionowski, T.2    Tuttle, D.L.3    Lenk, S.E.4    Dunn, W.J.5
  • 3
    • 0028230738 scopus 로고
    • Ultrastructural analysis of the autophagic process in yeast: Detection of autophagosomes and their characterization
    • Baba, M., Takeshige, K., Baba, N. and Ohsumi, Y. (1994) Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization. J. Cell Biol., 124, 903-913.
    • (1994) J. Cell Biol. , vol.124 , pp. 903-913
    • Baba, M.1    Takeshige, K.2    Baba, N.3    Ohsumi, Y.4
  • 4
    • 0027056174 scopus 로고
    • Yeast proteins associated with microtubules in vitro and in vivo
    • Barnes, G., Louie, K.A. and Botstein, D. (1992) Yeast proteins associated with microtubules in vitro and in vivo. Mol. Biol. Cell, 3, 29-47.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 29-47
    • Barnes, G.1    Louie, K.A.2    Botstein, D.3
  • 5
    • 0030945105 scopus 로고    scopus 로고
    • Signal transduction pathways in macroautophagy
    • Codogno, P., Ogier-Denis, E. and Houri, J.J. (1997) Signal transduction pathways in macroautophagy. Cell Signal, 9, 125-30.
    • (1997) Cell Signal , vol.9 , pp. 125-130
    • Codogno, P.1    Ogier-Denis, E.2    Houri, J.J.3
  • 7
    • 0025340880 scopus 로고
    • Studies on the mechanisms of autophagy: Maturation of the autophagic vacuole
    • Dunn, W.J. (1990) Studies on the mechanisms of autophagy: maturation of the autophagic vacuole. J. Cell Biol., 110, 1935-1945.
    • (1990) J. Cell Biol. , vol.110 , pp. 1935-1945
    • Dunn, W.J.1
  • 8
    • 0028222874 scopus 로고
    • Autophagy and related mechanisms of lysosome-mediated protein degradation
    • Dunn, W.J. (1994) Autophagy and related mechanisms of lysosome-mediated protein degradation. Trends Cell. Biol., 4, 139-143.
    • (1994) Trends Cell. Biol. , vol.4 , pp. 139-143
    • Dunn, W.J.1
  • 9
    • 0027716683 scopus 로고
    • Tracing intracellular proteolytic pathways. Proteolysis of fatty acid synthase and other cytoplasmic proteins in the yeast Saccharomyces cerevisiae
    • Egner, R., Thumm, M., Straub, M., Simeon, A., Schüller, H.J. and Wolf, D.H. (1993) Tracing intracellular proteolytic pathways. Proteolysis of fatty acid synthase and other cytoplasmic proteins in the yeast Saccharomyces cerevisiae. J. Biol. Chem., 268, 27269-27276.
    • (1993) J. Biol. Chem. , vol.268 , pp. 27269-27276
    • Egner, R.1    Thumm, M.2    Straub, M.3    Simeon, A.4    Schüller, H.J.5    Wolf, D.H.6
  • 10
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields, S. and Song, O. (1989) A novel genetic system to detect protein-protein interactions. Nature, 340, 245-246.
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.2
  • 11
    • 0028124463 scopus 로고
    • The two-hybrid system: An assay for protein-protein interactions
    • Fields, S. and Sternglanz, R. (1994) The two-hybrid system: an assay for protein-protein interactions. Trends Genet., 10, 286-292.
    • (1994) Trends Genet. , vol.10 , pp. 286-292
    • Fields, S.1    Sternglanz, R.2
  • 12
    • 0029994841 scopus 로고    scopus 로고
    • A new efficient gene disruption cassette for repeated use in budding yeast
    • Güldener, U., Heck, S., Fielder, T., Beinhauer, J. and Hegemann, J.H. (1996) A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res., 24, 2519-2524.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2519-2524
    • Güldener, U.1    Heck, S.2    Fielder, T.3    Beinhauer, J.4    Hegemann, J.H.5
  • 13
    • 0028800171 scopus 로고
    • Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway
    • Harding, T.M., Morano, K.A., Scott, S.V. and Klionsky, D.J. (1995) Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway. J. Cell Biol., 131, 591-602.
    • (1995) J. Cell Biol. , vol.131 , pp. 591-602
    • Harding, T.M.1    Morano, K.A.2    Scott, S.V.3    Klionsky, D.J.4
  • 14
    • 0029953575 scopus 로고    scopus 로고
    • Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole targeting pathway
    • Harding, T.M., Hefner-Gravink, A., Thumm, M. and Klionsky, D.J. (1996) Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole targeting pathway. J. Biol. Chem., 271, 17621-17624.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17621-17624
    • Harding, T.M.1    Hefner-Gravink, A.2    Thumm, M.3    Klionsky, D.J.4
  • 15
    • 0028912794 scopus 로고
    • A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae
    • Interthal, H., Bellocq, C., Bahler, J., Bashkirov, V.I., Edelstein, S. and Heyer, W.D. (1995) A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae. EMBO J., 14, 1057-1066.
    • (1995) EMBO J. , vol.14 , pp. 1057-1066
    • Interthal, H.1    Bellocq, C.2    Bahler, J.3    Bashkirov, V.I.4    Edelstein, S.5    Heyer, W.D.6
  • 16
    • 0030455820 scopus 로고    scopus 로고
    • Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
    • James, P., Halladay, J. and Craig, E.A. (1996) Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics, 144, 1425-1436.
    • (1996) Genetics , vol.144 , pp. 1425-1436
    • James, P.1    Halladay, J.2    Craig, E.A.3
  • 17
    • 0026640551 scopus 로고
    • Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway
    • Klionsky, D.J., Cueva, R. and Yaver, D.S. (1992) Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway. J. Cell Biol., 119, 287-299.
    • (1992) J. Cell Biol. , vol.119 , pp. 287-299
    • Klionsky, D.J.1    Cueva, R.2    Yaver, D.S.3
  • 18
    • 0023156677 scopus 로고
    • 18 kDa microtubule-associated protein: Identification as a new light chain (LC-3) of microtubule-associated protein 1 (MAP-1)
    • Kuznetsov, S.A. and Gelfand, V.I. (1987) 18 kDa microtubule-associated protein: identification as a new light chain (LC-3) of microtubule-associated protein 1 (MAP-1). FEBS Lett., 212, 145-148.
    • (1987) FEBS Lett. , vol.212 , pp. 145-148
    • Kuznetsov, S.A.1    Gelfand, V.I.2
  • 19
    • 0026754019 scopus 로고
    • Autophagic vacuoles rapidly fuse with pre-existing lysosomes in cultured hepatocytes
    • Lawrence, B.P. and Brown, W.J. (1992) Autophagic vacuoles rapidly fuse with pre-existing lysosomes in cultured hepatocytes. J. Cell Sci., 102, 515-526.
    • (1992) J. Cell Sci. , vol.102 , pp. 515-526
    • Lawrence, B.P.1    Brown, W.J.2
  • 20
    • 0028289946 scopus 로고
    • Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B
    • Mann, S.S. and Hammarback, J.A. (1994) Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B. J. Biol. Chem., 269, 11492-11497.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11492-11497
    • Mann, S.S.1    Hammarback, J.A.2
  • 21
    • 0029871731 scopus 로고    scopus 로고
    • Gene localization and developmental expression of light chain 3: A common subunit of microtubule-associated protein 1A (MAP1A) and MAP1B
    • Mann, S.S. and Hammarback, J.A. (1996) Gene localization and developmental expression of light chain 3: a common subunit of microtubule-associated protein 1A (MAP1A) and MAP1B. J. Neurosci. Res., 43, 535-544.
    • (1996) J. Neurosci. Res. , vol.43 , pp. 535-544
    • Mann, S.S.1    Hammarback, J.A.2
  • 22
    • 0025242871 scopus 로고
    • A tandem of alpha-tubulin genes preferentially expressed in radicular tissues from Zea mays
    • Montoliu, L., Rigau, J. and Puigdomenech, P. (1990) A tandem of alpha-tubulin genes preferentially expressed in radicular tissues from Zea mays. Plant Mol. Biol., 14, 1-15.
    • (1990) Plant Mol. Biol. , vol.14 , pp. 1-15
    • Montoliu, L.1    Rigau, J.2    Puigdomenech, P.3
  • 24
    • 0029983745 scopus 로고    scopus 로고
    • Modulation of microtubule shape in vitro by high molecular weight microtubule associated proteins MAP1A, MAP1B, and MAP2
    • Pedrotti, B., Francolini, M., Cotelli, F. and Islam, K. (1996). Modulation of microtubule shape in vitro by high molecular weight microtubule associated proteins MAP1A, MAP1B, and MAP2. FEBS Lett., 384, 147-150.
    • (1996) FEBS Lett. , vol.384 , pp. 147-150
    • Pedrotti, B.1    Francolini, M.2    Cotelli, F.3    Islam, K.4
  • 25
    • 0023545322 scopus 로고
    • A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector
    • Rose, M.D., Novick, P., Thomas, J.H., Botstein, D. and Fink, G.R. (1987) A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene, 60, 237-243.
    • (1987) Gene , vol.60 , pp. 237-243
    • Rose, M.D.1    Novick, P.2    Thomas, J.H.3    Botstein, D.4    Fink, G.R.5
  • 26
    • 0024709423 scopus 로고
    • Microtubule-associated protein 1B: Molecular structure, localization, and phosphorylation-dependent expression in developing neurons
    • Sato-Yoshitake, R., Shiomura, Y., Miyasaka, H. and Hirokawa, N. (1989) Microtubule-associated protein 1B: molecular structure, localization, and phosphorylation-dependent expression in developing neurons. Neuron, 3, 229-238.
    • (1989) Neuron , vol.3 , pp. 229-238
    • Sato-Yoshitake, R.1    Shiomura, Y.2    Miyasaka, H.3    Hirokawa, N.4
  • 27
    • 0023811994 scopus 로고
    • Isolation and characterization of conditional-lethal mutations in the TUB1 alphatubulin gene of the yeast Saccharomyces cerevisiae
    • Schatz, P.J., Solomon, F. and Botstein, D. (1988) Isolation and characterization of conditional-lethal mutations in the TUB1 alphatubulin gene of the yeast Saccharomyces cerevisiae. Genetics. 120, 681-695.
    • (1988) Genetics , vol.120 , pp. 681-695
    • Schatz, P.J.1    Solomon, F.2    Botstein, D.3
  • 29
    • 0029913505 scopus 로고    scopus 로고
    • Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole
    • Scott, S.V., Hefner-Gravink, A., Morano, K.A., Noda, T., Ohsumi, Y. and Klionsky, D.J. (1996) Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole. Proc. Natl Acad. Sci. USA, 93, 12304-12308.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 12304-12308
    • Scott, S.V.1    Hefner-Gravink, A.2    Morano, K.A.3    Noda, T.4    Ohsumi, Y.5    Klionsky, D.J.6
  • 31
    • 0023262970 scopus 로고
    • The molecular structure of microtubule-associated protein 1A (MAP1A) in vivo and in vitro. An immunoelectron microscopy and quick-freeze, deep-etch study
    • Shiomura, Y. and Hirokawa, N. (1987) The molecular structure of microtubule-associated protein 1A (MAP1A) in vivo and in vitro. An immunoelectron microscopy and quick-freeze, deep-etch study. J. Neurosci., 7, 1461-1469.
    • (1987) J. Neurosci. , vol.7 , pp. 1461-1469
    • Shiomura, Y.1    Hirokawa, N.2
  • 32
    • 0025748574 scopus 로고
    • Analyses of the cytoskeleton in Saccharomyces cerevisiae
    • Solomon, F. (1991) Analyses of the cytoskeleton in Saccharomyces cerevisiae. Annu. Rev. Cell Biol., 7, 633-662.
    • (1991) Annu. Rev. Cell Biol. , vol.7 , pp. 633-662
    • Solomon, F.1
  • 33
    • 0029257355 scopus 로고
    • Green fluorescent protein. the green revolution
    • Stearns, T. (1995) Green fluorescent protein. The green revolution. Curr. Biol., 5, 262-264.
    • (1995) Curr. Biol. , vol.5 , pp. 262-264
    • Stearns, T.1
  • 34
    • 0031008471 scopus 로고    scopus 로고
    • AUT3, a serine/ threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae
    • Straub, M., Bredschneider, M. and Thumm, M. (1997) AUT3, a serine/ threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae. J. Bacteriol., 179, 3875-3883.
    • (1997) J. Bacteriol. , vol.179 , pp. 3875-3883
    • Straub, M.1    Bredschneider, M.2    Thumm, M.3
  • 36
    • 0028676232 scopus 로고
    • New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
    • Wach, A., Brachat, A., Pohlmann, R. and Philippsen, P. (1994) New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast, 10, 1793-1808.
    • (1994) Yeast , vol.10 , pp. 1793-1808
    • Wach, A.1    Brachat, A.2    Pohlmann, R.3    Philippsen, P.4
  • 37
    • 0028295681 scopus 로고
    • 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans
    • Wilson, R. et al. (1994) 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature, 368, 32-38.
    • (1994) Nature , vol.368 , pp. 32-38
    • Wilson, R.1
  • 38
    • 0031110140 scopus 로고    scopus 로고
    • Review: An overview of the Saccharomvces cerevisiae microtubule and microfilament cytoskeleton
    • Winsor, B. and Schiebel, E. (1997) Review: an overview of the Saccharomvces cerevisiae microtubule and microfilament cytoskeleton. Yeast, 13, 399-434.
    • (1997) Yeast , vol.13 , pp. 399-434
    • Winsor, B.1    Schiebel, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.