-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J and Ward E: Cancer statistics, 2010. CA Cancer J Clin 60: 277-300, 2010.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
2
-
-
38049040752
-
Adjuvant therapy for pancreatic cancer: A review
-
Zuckerman DS and Ryan DP: Adjuvant therapy for pancreatic cancer: a review. Cancer 112: 243-249, 2008.
-
(2008)
Cancer
, vol.112
, pp. 243-249
-
-
Zuckerman, D.S.1
Ryan, D.P.2
-
3
-
-
33645294070
-
Oncomirs - microRNAs with a role in cancer
-
Esquela-Kerscher A and Slack FJ: Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6: 259-269, 2006.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
4
-
-
9144224451
-
Processing of primary microRNAs by the microprocessor complex
-
Denli AM, Tops BB, Plasterk RH, Ketting RF and Hannon GJ: Processing of primary microRNAs by the microprocessor complex. Nature 432: 231-235, 2004.
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
5
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
-
Wightman B, Ha I and Ruvkun G: Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855-862, 1993.
-
(1993)
Cell
, vol.75
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
6
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart BJ, Slack FJ, Basson M, et al: The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403: 901-906, 2000.
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
Slack, F.J.2
Basson, M.3
-
7
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M, et al: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99: 15524-15529, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
8
-
-
34247862190
-
microRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis
-
Bloomston M, Frankel WL, Petrocca F, et al: microRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 229: 1901-1908, 2007.
-
(2007)
JAMA
, vol.229
, pp. 1901-1908
-
-
Bloomston, M.1
Frankel, W.L.2
Petrocca, F.3
-
9
-
-
52049097315
-
Altered microRNA expression in cervical carcinomas
-
Lee JW, Choi CH, Choi JJ, et al: Altered microRNA expression in cervical carcinomas. Clin Cancer Res 14: 2535-2542, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2535-2542
-
-
Lee, J.W.1
Choi, C.H.2
Choi, J.J.3
-
10
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
Iorio MV, Ferracin M, Liu CG, et al: MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65: 7065-7070, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 7065-7070
-
-
Iorio, M.V.1
Ferracin, M.2
Liu, C.G.3
-
11
-
-
40949087185
-
Identification of metastasis-related microRNAs in hepatocellular carcinoma
-
Budhu A, Jia HL, Forgues M, et al: Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 47: 897-907, 2008.
-
(2008)
Hepatology
, vol.47
, pp. 897-907
-
-
Budhu, A.1
Jia, H.L.2
Forgues, M.3
-
12
-
-
35148886434
-
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
-
Ma L, Teruya-Feldstein J and Weinberg RA: Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449: 682-688, 2007.
-
(2007)
Nature
, vol.449
, pp. 682-688
-
-
Ma, L.1
Teruya-Feldstein, J.2
Weinberg, R.A.3
-
13
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST and Patel T: MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658, 2007.
-
(2007)
Gastroenterology
, vol.133
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
14
-
-
41749113108
-
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
-
Asangani IA, Rasheed SA, Nikolova DA, et al: MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128-2136, 2008.
-
(2008)
Oncogene
, vol.27
, pp. 2128-2136
-
-
Asangani, I.A.1
Rasheed, S.A.2
Nikolova, D.A.3
-
15
-
-
40449131878
-
Loss of mir-146a function in hormone-refractory prostate cancer
-
Lin SL, Chiang A, Chang D and Ying SY: Loss of mir-146a function in hormone-refractory prostate cancer. RNA 14: 417-424, 2008.
-
(2008)
RNA
, vol.14
, pp. 417-424
-
-
Lin, S.L.1
Chiang, A.2
Chang, D.3
Ying, S.Y.4
-
16
-
-
48949115082
-
MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines
-
Crawford M, Brawner E, Batte K, et al: MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines. Biochem Biophys Res Commun 373: 607-612, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.373
, pp. 607-612
-
-
Crawford, M.1
Brawner, E.2
Batte, K.3
-
17
-
-
38849107424
-
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
-
Huang Q, Gumireddy K, Schrier M, et al: The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 10: 202-210, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 202-210
-
-
Huang, Q.1
Gumireddy, K.2
Schrier, M.3
-
18
-
-
77956296766
-
Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer
-
Hwang JH, Voortman J, Giovannetti E, et al: Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer. PloS One 5: e10630, 2010.
-
(2010)
PloS One
, vol.5
, pp. 10630
-
-
Hwang, J.H.1
Voortman, J.2
Giovannetti, E.3
-
19
-
-
77953169001
-
MicroRNA-21 in pancreatic cancer: Correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity
-
Giovannetti E, Funel N, Peters GJ, et al: MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity. Cancer Res 70: 4528-4538, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 4528-4538
-
-
Giovannetti, E.1
Funel, N.2
Peters, G.J.3
-
20
-
-
66849124564
-
MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance
-
Moriyama T, Ohuchida K, Mizumoto K, et al: MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance. Mol Cancer Ther 8: 1067-1074, 2009.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1067-1074
-
-
Moriyama, T.1
Ohuchida, K.2
Mizumoto, K.3
-
21
-
-
52149102044
-
Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells
-
Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J and Benz CC: Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene 27: 5643-5647, 2008.
-
(2008)
Oncogene
, vol.27
, pp. 5643-5647
-
-
Bhaumik, D.1
Scott, G.K.2
Schokrpur, S.3
Patil, C.K.4
Campisi, J.5
Benz, C.C.6
-
22
-
-
79960336510
-
Clinical significance of miR-146a in gastric cancer cases
-
Kogo R, Mimori K, Tanaka F, Komune S and Mori M: Clinical significance of miR-146a in gastric cancer cases. Clin Cancer Res 17: 4277-4284, 2011.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4277-4284
-
-
Kogo, R.1
Mimori, K.2
Tanaka, F.3
Komune, S.4
Mori, M.5
-
23
-
-
0037242595
-
Function of nuclear factor kappaB in pancreatic cancer metastasis
-
Fujioka S, Sclabas GM, Schmidt C, et al: Function of nuclear factor kappaB in pancreatic cancer metastasis. Clin Cancer Res 9: 346-354, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 346-354
-
-
Fujioka, S.1
Sclabas, G.M.2
Schmidt, C.3
-
24
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M: Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-436, 2006.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
25
-
-
76749152907
-
MiR-146a suppresses invasion of pancreatic cancer cells
-
Li Y, Vandenboom TG II, Wang Z, et al: miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res 70: 1486-1495, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 1486-1495
-
-
Li, Y.1
Vandenboom, T.G.I.I.2
Wang, Z.3
-
26
-
-
80455174863
-
Inhibitory effects of miR-146b-5p on cell migration and invasion of pancreatic cancer by targeting MMP16
-
Lin F, Wang X, Jie Z, et al: Inhibitory effects of miR-146b-5p on cell migration and invasion of pancreatic cancer by targeting MMP16. J Huazhong Univ Sci Technolog Med Sci 31: 509-514, 2011.
-
(2011)
J Huazhong Univ Sci Technolog Med Sci
, vol.31
, pp. 509-514
-
-
Lin, F.1
Wang, X.2
Jie, Z.3
-
27
-
-
77957948990
-
MiR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2
-
Ma Y, Yu S, Zhao W, Lu Z and Chen J: miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2. Cancer Lett 298: 150-158, 2010.
-
(2010)
Cancer Lett
, vol.298
, pp. 150-158
-
-
Ma, Y.1
Yu, S.2
Zhao, W.3
Lu, Z.4
Chen, J.5
-
28
-
-
77953950190
-
MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation
-
Yu J, Ohuchida K, Mizumoto K, et al: MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation. Mol Cancer 9: 169, 2010.
-
(2010)
Mol Cancer
, vol.9
, pp. 169
-
-
Yu, J.1
Ohuchida, K.2
Mizumoto, K.3
-
29
-
-
77955517749
-
hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations
-
Wang F, Xue X, Wei J, et al: hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations. Br J Cancer 103: 567-574, 2010.
-
(2010)
Br J Cancer
, vol.103
, pp. 567-574
-
-
Wang, F.1
Xue, X.2
Wei, J.3
-
30
-
-
80052445088
-
MicroRNA-10b expression correlates with response to neoadjuvant therapy and survival in pancreatic ductal adenocarcinoma
-
Preis M, Gardner TB, Gordon SR, et al: MicroRNA-10b expression correlates with response to neoadjuvant therapy and survival in pancreatic ductal adenocarcinoma. Clin Cancer Res 17: 5812-5821, 2011.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5812-5821
-
-
Preis, M.1
Gardner, T.B.2
Gordon, S.R.3
-
31
-
-
81855183857
-
MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells
-
Srivastava SK, Bhardwaj A, Singh S, et al: MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. Carcinogenesis 32: 1832-1839, 2011.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1832-1839
-
-
Srivastava, S.K.1
Bhardwaj, A.2
Singh, S.3
-
32
-
-
78049265813
-
MicroRNA miR-17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion
-
Yu J, Ohuchida K, Mizumoto K, Fujita H, Nakata K and Tanaka M: MicroRNA miR-17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion. Cancer Biol Ther 10: 748-757, 2010.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 748-757
-
-
Yu, J.1
Ohuchida, K.2
Mizumoto, K.3
Fujita, H.4
Nakata, K.5
Tanaka, M.6
-
33
-
-
70350596499
-
MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines
-
Muniyappa MK, Dowling P, Henry M, et al: MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. Eur J Cancer 45: 3104-3118, 2009.
-
(2009)
Eur J Cancer
, vol.45
, pp. 3104-3118
-
-
Muniyappa, M.K.1
Dowling, P.2
Henry, M.3
-
34
-
-
78650096337
-
MicroRNA-20a overexpression inhibited proliferation and metastasis of pancreatic carcinoma cells
-
Yan H, Wu J, Liu W, et al: MicroRNA-20a overexpression inhibited proliferation and metastasis of pancreatic carcinoma cells. Hum Gene Ther 21: 1723-1734, 2010.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 1723-1734
-
-
Yan, H.1
Wu, J.2
Liu, W.3
-
35
-
-
84855992618
-
MiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM9
-
Hamada S, Satoh K, Fujibuchi W, et al: MiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM9. Mol Cancer Res 10: 3-10, 2012.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 3-10
-
-
Hamada, S.1
Satoh, K.2
Fujibuchi, W.3
-
36
-
-
84862777219
-
Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells
-
Li W, Yuan Y, Huang L, Qiao M and Zhang Y: Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells. Diabetes Res Clin Pract 96: 187-195, 2012.
-
(2012)
Diabetes Res Clin Pract
, vol.96
, pp. 187-195
-
-
Li, W.1
Yuan, Y.2
Huang, L.3
Qiao, M.4
Zhang, Y.5
-
37
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY and Nieto MA: Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890, 2009.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
38
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
Thiery JP and Sleeman JP: Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7: 131-142, 2006.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
39
-
-
33749024777
-
Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
-
Christiansen JJ and Rajasekaran AK: Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 66: 8319-8326, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 8319-8326
-
-
Christiansen, J.J.1
Rajasekaran, A.K.2
-
40
-
-
84863115473
-
Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition
-
Xiong H, Hong J, Du W, et al: Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition. J Biol Chem 287: 5819-5832, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 5819-5832
-
-
Xiong, H.1
Hong, J.2
Du, W.3
-
41
-
-
77954030498
-
NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells
-
Maier HJ, Schmidt-Strassburger U, Huber MA, Wiedemann EM, Beug H and Wirth T: NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. Cancer Lett 295: 214-228, 2010.
-
(2010)
Cancer Lett
, vol.295
, pp. 214-228
-
-
Maier, H.J.1
Schmidt-Strassburger, U.2
Huber, M.A.3
Wiedemann, E.M.4
Beug, H.5
Wirth, T.6
-
42
-
-
39049160267
-
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
-
Spaderna S, Schmalhofer O, Wahlbuhl M, et al: The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res 68: 537-544, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 537-544
-
-
Spaderna, S.1
Schmalhofer, O.2
Wahlbuhl, M.3
-
43
-
-
47249091921
-
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
-
Korpal M, Lee ES, Hu G and Kang Y: The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 283: 14910-14914, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
Kang, Y.4
-
44
-
-
44649163918
-
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
-
Burk U, Schubert J, Wellner U, et al: A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 9: 582-589, 2008.
-
(2008)
EMBO Rep
, vol.9
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
-
45
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner U, Schubert J, Burk UC, et al: The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 11: 1487-1495, 2009.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
-
46
-
-
68949213672
-
Let-7 microRNA transfer in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor progression
-
Torrisani J, Bournet B, du Rieu MC, et al: let-7 microRNA transfer in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor progression. Hum Gene Ther 20: 831-844, 2009.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 831-844
-
-
Torrisani, J.1
Bournet, B.2
du Rieu, M.C.3
-
47
-
-
78650211014
-
Differentially expressed miRNAs in the plasma may provide a molecular signature for aggressive pancreatic cancer
-
Ali S, Almhanna K, Chen W, Philip PA and Sarkar FH: Differentially expressed miRNAs in the plasma may provide a molecular signature for aggressive pancreatic cancer. Am J Transl Res 3: 28-47, 2010.
-
(2010)
Am J Transl Res
, vol.3
, pp. 28-47
-
-
Ali, S.1
Almhanna, K.2
Chen, W.3
Philip, P.A.4
Sarkar, F.H.5
-
48
-
-
69249096109
-
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
-
Li Y, VandenBoom TG II, Kong D, et al: Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res 69: 6704-6712, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 6704-6712
-
-
Li, Y.1
Vandenboom, T.G.I.I.2
Kong, D.3
-
49
-
-
33644560281
-
Cancer stem cells: An old idea - a paradigm shift
-
discussion 1895-1896
-
Wicha MS, Liu S and Dontu G: Cancer stem cells: an old idea - a paradigm shift. Cancer Res 66: 1883-1890; discussion 1895-1896, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 1883-1890
-
-
Wicha, M.S.1
Liu, S.2
Dontu, G.3
-
50
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D and Dick JE: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3: 730-737, 1997.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
51
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, et al: Identification of human brain tumour initiating cells. Nature 432: 396-401, 2004.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
52
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ and Clarke MF: Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Scie USA 100: 3983-3988, 2003.
-
(2003)
Proc Natl Acad Scie USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
53
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S and Dick JE: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445: 106-110, 2007.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
54
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P, et al: Identification of pancreatic cancer stem cells. Cancer Res 67: 1030-1037, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
-
55
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
Hermann PC, Huber SL, Herrler T, et al: Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1: 313-323, 2007.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
-
56
-
-
77954921889
-
Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells
-
Moriyama T, Ohuchida K, Mizumoto K, et al: Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells. Cancer 116: 3357-3368, 2010.
-
(2010)
Cancer
, vol.116
, pp. 3357-3368
-
-
Moriyama, T.1
Ohuchida, K.2
Mizumoto, K.3
-
57
-
-
77955599004
-
Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas
-
May R, Sureban SM, Lightfoot SA, et al: Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas. Am J Physiol Gastrointest Liver Physiol 299: G303-310, 2010.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.299
, pp. 303-310
-
-
May, R.1
Sureban, S.M.2
Lightfoot, S.A.3
-
58
-
-
79952748822
-
DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism
-
Sureban SM, May R, Lightfoot SA, et al: DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism. Cancer Res 71: 2328-2338, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 2328-2338
-
-
Sureban, S.M.1
May, R.2
Lightfoot, S.A.3
-
59
-
-
34250868124
-
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-arrest
-
Tarasov V, Jung P, Verdoodt B, et al: Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6: 1586-1593, 2007.
-
(2007)
Cell Cycle
, vol.6
, pp. 1586-1593
-
-
Tarasov, V.1
Jung, P.2
Verdoodt, B.3
-
60
-
-
34547458550
-
P53-mediated activation of miRNA34 candidate tumor-suppressor genes
-
Bommer GT, Gerin I, Feng Y, et al: p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 17: 1298-1307, 2007.
-
(2007)
Curr Biol
, vol.17
, pp. 1298-1307
-
-
Bommer, G.T.1
Gerin, I.2
Feng, Y.3
-
61
-
-
69949087531
-
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
-
Ji Q, Hao X, Zhang M, et al: MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PloS One 4: e6816, 2009.
-
(2009)
PloS One
, vol.4
, pp. 6816
-
-
Ji, Q.1
Hao, X.2
Zhang, M.3
-
62
-
-
53949090314
-
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
-
Ji Q, Hao X, Meng Y, et al: Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 8: 266, 2008.
-
(2008)
BMC Cancer
, vol.8
, pp. 266
-
-
Ji, Q.1
Hao, X.2
Meng, Y.3
-
63
-
-
84855405573
-
Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression
-
Bao B, Ali S, Banerjee S, et al: Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression. Cancer Res 72: 335-345, 2012.
-
(2012)
Cancer Res
, vol.72
, pp. 335-345
-
-
Bao, B.1
Ali, S.2
Banerjee, S.3
-
66
-
-
50849104230
-
Notch tumor suppressor function
-
Dotto GP: Notch tumor suppressor function. Oncogene 27: 5115-5123, 2008.
-
(2008)
Oncogene
, vol.27
, pp. 5115-5123
-
-
Dotto, G.P.1
-
67
-
-
33645049305
-
Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells
-
Wang Z, Banerjee S, Li Y, Rahman KM, Zhang Y and Sarkar FH: Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. Cancer Res 66: 2778-2784, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 2778-2784
-
-
Wang, Z.1
Banerjee, S.2
Li, Y.3
Rahman, K.M.4
Zhang, Y.5
Sarkar, F.H.6
-
68
-
-
70349751655
-
Development and cancer: At the crossroads of Nodal and Notch signaling
-
Strizzi L, Hardy KM, Seftor EA, et al: Development and cancer: at the crossroads of Nodal and Notch signaling. Cancer Res 69: 7131-7134, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 7131-7134
-
-
Strizzi, L.1
Hardy, K.M.2
Seftor, E.A.3
-
69
-
-
77951096677
-
Targeting Notch signaling in pancreatic cancer
-
Ristorcelli E and Lombardo D: Targeting Notch signaling in pancreatic cancer. Expert Opin Ther Targets 14: 541-552, 2010.
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 541-552
-
-
Ristorcelli, E.1
Lombardo, D.2
-
70
-
-
80052316514
-
Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells
-
Nalls D, Tang SN, Rodova M, Srivastava RK and Shankar S: Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells. PloS One 6: e24099, 2011.
-
(2011)
PloS One
, vol.6
, pp. 24099
-
-
Nalls, D.1
Tang, S.N.2
Rodova, M.3
Srivastava, R.K.4
Shankar, S.5
-
71
-
-
79957487931
-
Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
-
Bao B, Wang Z, Ali S, et al: Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett 307: 26-36, 2011.
-
(2011)
Cancer Lett
, vol.307
, pp. 26-36
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
-
72
-
-
81555232930
-
Molecular pathogenesis of pancreatic cancer and clinical perspectives
-
Matthaios D, Zarogoulidis P, Balgouranidou I, Chatzaki E and Kakolyris S: Molecular pathogenesis of pancreatic cancer and clinical perspectives. Oncology 81: 259-272, 2011.
-
(2011)
Oncology
, vol.81
, pp. 259-272
-
-
Matthaios, D.1
Zarogoulidis, P.2
Balgouranidou, I.3
Chatzaki, E.4
Kakolyris, S.5
-
73
-
-
33947254016
-
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: A new paradigm for combination therapy in solid cancers
-
Feldmann G, Dhara S, Fendrich V, et al: Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers. Cancer Res 67: 2187-2196, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 2187-2196
-
-
Feldmann, G.1
Dhara, S.2
Fendrich, V.3
-
74
-
-
53549129980
-
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells
-
Ferretti E, De Smaele E, Miele E, et al: Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells. EMBO J 27: 2616-2627, 2008.
-
(2008)
EMBO J
, vol.27
, pp. 2616-2627
-
-
Ferretti, E.1
de Smaele, E.2
Miele, E.3
-
75
-
-
65249186793
-
The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors
-
Northcott PA, Fernandez LA, Hagan JP, et al: The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors. Cancer Res 69: 3249-3255, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 3249-3255
-
-
Northcott, P.A.1
Fernandez, L.A.2
Hagan, J.P.3
-
76
-
-
48849104705
-
Control of antagonistic components of the hedgehog signaling pathway by microRNAs in Drosophila
-
Friggi-Grelin F, Lavenant-Staccini L and Therond P: Control of antagonistic components of the hedgehog signaling pathway by microRNAs in Drosophila. Genetics 179: 429-439, 2008.
-
(2008)
Genetics
, vol.179
, pp. 429-439
-
-
Friggi-Grelin, F.1
Lavenant-Staccini, L.2
Therond, P.3
-
77
-
-
33751264968
-
Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells
-
Tsuda N, Ishiyama S, Li Y, Ioannides CG, Abbruzzese JL and Chang DZ: Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells. Clin Cancer Res 12: 6557-6564, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6557-6564
-
-
Tsuda, N.1
Ishiyama, S.2
Li, Y.3
Ioannides, C.G.4
Abbruzzese, J.L.5
Chang, D.Z.6
-
78
-
-
77955033963
-
MiRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer
-
Yu S, Lu Z, Liu C, et al: miRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer. Cancer Res 70: 6015-6025, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 6015-6025
-
-
Yu, S.1
Lu, Z.2
Liu, C.3
-
79
-
-
79954455860
-
Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas
-
Vogt M, Munding J, Gruner M, et al: Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. Virchows Arch 458: 313-322, 2011.
-
(2011)
Virchows Arch
, vol.458
, pp. 313-322
-
-
Vogt, M.1
Munding, J.2
Gruner, M.3
-
80
-
-
34147096292
-
Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression
-
Tashiro E, Tsuchiya A and Imoto M: Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression. Cancer Sci 98: 629-635, 2007.
-
(2007)
Cancer Sci
, vol.98
, pp. 629-635
-
-
Tashiro, E.1
Tsuchiya, A.2
Imoto, M.3
-
81
-
-
65449166892
-
Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer
-
Lee KH, Lotterman C, Karikari C, et al: Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology 9: 293-301, 2009.
-
(2009)
Pancreatology
, vol.9
, pp. 293-301
-
-
Lee, K.H.1
Lotterman, C.2
Karikari, C.3
-
82
-
-
0031944607
-
CD40 and CD154 in cell-mediated immunity
-
Grewal IS and Flavell RA: CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 16: 111-135, 1998.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 111-135
-
-
Grewal, I.S.1
Flavell, R.A.2
-
83
-
-
0032704976
-
What is the real role of CD40 in cancer immunotherapy?
-
Costello RT, Gastaut JA and Olive D: What is the real role of CD40 in cancer immunotherapy? Immunology Today 20: 488-493, 1999.
-
(1999)
Immunology Today
, vol.20
, pp. 488-493
-
-
Costello, R.T.1
Gastaut, J.A.2
Olive, D.3
-
84
-
-
67650999145
-
Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas
-
Mees ST, Mardin WA, Sielker S, et al: Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas. Ann Surg Oncol 16: 2339-2350, 2009.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2339-2350
-
-
Mees, S.T.1
Mardin, W.A.2
Sielker, S.3
-
85
-
-
0033000990
-
Histone acetylases and deacetylases in cell proliferation
-
Kouzarides T: Histone acetylases and deacetylases in cell proliferation. Curr Opin Genet Dev 9: 40-48, 1999.
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 40-48
-
-
Kouzarides, T.1
-
86
-
-
0031439397
-
Adenoviral E1A-associated protein p300 is involved in acute myeloid leukemia with t(11;22)(q23;q13)
-
Ida K, Kitabayashi I, Taki T, et al: Adenoviral E1A-associated protein p300 is involved in acute myeloid leukemia with t(11;22)(q23;q13). Blood 90: 4699-4704, 1997.
-
(1997)
Blood
, vol.90
, pp. 4699-4704
-
-
Ida, K.1
Kitabayashi, I.2
Taki, T.3
-
87
-
-
73449085536
-
EP300 - a miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas
-
Mees ST, Mardin WA, Wendel C, et al: EP300 - a miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas. Int J Cancer 126: 114-124, 2010.
-
(2010)
Int J Cancer
, vol.126
, pp. 114-124
-
-
Mees, S.T.1
Mardin, W.A.2
Wendel, C.3
|