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Volumn 131, Issue 6, 2012, Pages 959-975

Drosophila melanogaster as a model to study drug addiction

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALCOHOL; COCAINE; CYCLIC AMP; EPIDERMAL GROWTH FACTOR RECEPTOR; NICOTINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 84862680694     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-012-1146-6     Document Type: Review
Times cited : (120)

References (140)
  • 1
    • 0037173086 scopus 로고    scopus 로고
    • Cocaine sensitization and reward are under the influence of circadian genes and rhythm
    • 12084940 1:CAS:528:DC%2BD38XltF2hurk%3D 10.1073/pnas.142039099
    • C Abarca U Albrecht R Spanagel 2002 Cocaine sensitization and reward are under the influence of circadian genes and rhythm Proc Natl Acad Sci USA 99 9026 9030 12084940 1:CAS:528:DC%2BD38XltF2hurk%3D 10.1073/pnas.142039099
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9026-9030
    • Abarca, C.1    Albrecht, U.2    Spanagel, R.3
  • 2
    • 79955040212 scopus 로고    scopus 로고
    • Not(ch) just development: Notch signalling in the adult brain
    • 21505516 1:CAS:528:DC%2BC3MXkvVKqtL0%3D 10.1038/nrn3024
    • JL Ables JJ Breunig AJ Eisch P Rakic 2011 Not(ch) just development: Notch signalling in the adult brain Nat Rev Neurosci 12 269 283 21505516 1:CAS:528:DC%2BC3MXkvVKqtL0%3D 10.1038/nrn3024
    • (2011) Nat Rev Neurosci , vol.12 , pp. 269-283
    • Ables, J.L.1    Breunig, J.J.2    Eisch, A.J.3    Rakic, P.4
  • 5
    • 0033551867 scopus 로고    scopus 로고
    • Requirement of circadian genes for cocaine sensitization in Drosophila
    • 10446052 1:CAS:528:DyaK1MXlt1Gnu78%3D 10.1126/science.285.5430.1066
    • R Andretic S Chaney J Hirsh 1999 Requirement of circadian genes for cocaine sensitization in Drosophila Science 285 1066 1068 10446052 1:CAS:528:DyaK1MXlt1Gnu78%3D 10.1126/science.285.5430.1066
    • (1999) Science , vol.285 , pp. 1066-1068
    • Andretic, R.1    Chaney, S.2    Hirsh, J.3
  • 6
    • 21844480910 scopus 로고    scopus 로고
    • Dopaminergic modulation of arousal in Drosophila
    • 16005288 1:CAS:528:DC%2BD2MXlvFygs7g%3D 10.1016/j.cub.2005.05.025
    • R Andretic B van Swinderen RJ Greenspan 2005 Dopaminergic modulation of arousal in Drosophila Curr Biol 15 1165 1175 16005288 1:CAS:528: DC%2BD2MXlvFygs7g%3D 10.1016/j.cub.2005.05.025
    • (2005) Curr Biol , vol.15 , pp. 1165-1175
    • Andretic, R.1    Van Swinderen, B.2    Greenspan, R.J.3
  • 7
    • 68649120921 scopus 로고    scopus 로고
    • Tolerance in Drosophila
    • 19180359 10.1080/01677060802572937
    • NS Atkinson 2009 Tolerance in Drosophila J Neurogenet 23 293 302 19180359 10.1080/01677060802572937
    • (2009) J Neurogenet , vol.23 , pp. 293-302
    • Atkinson, N.S.1
  • 8
    • 0034708062 scopus 로고    scopus 로고
    • Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila
    • 10704411 1:CAS:528:DC%2BD3cXhsFKrtrs%3D 10.1016/S0960-9822(00)00336-5
    • RJ Bainton LT Tsai CM Singh MS Moore WS Neckameyer U Heberlein 2000 Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila Curr Biol 10 187 194 10704411 1:CAS:528:DC%2BD3cXhsFKrtrs%3D 10.1016/S0960-9822(00)00336-5
    • (2000) Curr Biol , vol.10 , pp. 187-194
    • Bainton, R.J.1    Tsai, L.T.2    Singh, C.M.3    Moore, M.S.4    Neckameyer, W.S.5    Heberlein, U.6
  • 9
    • 26244436194 scopus 로고    scopus 로고
    • Moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila
    • 16213219 1:CAS:528:DC%2BD2MXhtFelt7bK 10.1016/j.cell.2005.07.029
    • RJ Bainton LT Tsai T Schwabe M DeSalva U Gaul U Heberlein 2005 moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila Cell 123 145 156 16213219 1:CAS:528: DC%2BD2MXhtFelt7bK 10.1016/j.cell.2005.07.029
    • (2005) Cell , vol.123 , pp. 145-156
    • Bainton, R.J.1    Tsai, L.T.2    Schwabe, T.3    Desalva, M.4    Gaul, U.5    Heberlein, U.6
  • 10
    • 0025669867 scopus 로고
    • Spacing differentiation in the developing Drosophila eye: A fibrinogen-related lateral inhibitor encoded by scabrous
    • 2175046 1:CAS:528:DyaK3MXit1amsrw%3D 10.1126/science.2175046
    • NE Baker M Mlodzik GM Rubin 1990 Spacing differentiation in the developing Drosophila eye: a fibrinogen-related lateral inhibitor encoded by scabrous Science 250 1370 1377 2175046 1:CAS:528:DyaK3MXit1amsrw%3D 10.1126/science.2175046
    • (1990) Science , vol.250 , pp. 1370-1377
    • Baker, N.E.1    Mlodzik, M.2    Rubin, G.M.3
  • 12
    • 6344255311 scopus 로고    scopus 로고
    • Rapid and chronic: Two distinct forms of ethanol tolerance in Drosophila
    • 15597078 1:CAS:528:DC%2BD2cXhtVWkurzE 10.1097/01.ALC.0000141817.15993.98
    • KH Berger U Heberlein MS Moore 2004 Rapid and chronic: two distinct forms of ethanol tolerance in Drosophila Alcohol Clin Exp Res 28 1469 1480 15597078 1:CAS:528:DC%2BD2cXhtVWkurzE 10.1097/01.ALC.0000141817.15993.98
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 1469-1480
    • Berger, K.H.1    Heberlein, U.2    Moore, M.S.3
  • 13
    • 42549125450 scopus 로고    scopus 로고
    • Ethanol sensitivity and tolerance in long-term memory mutants of Drosophila melanogaster
    • 18435628 1:CAS:528:DC%2BD1cXmvVShtbg%3D 10.1111/j.1530-0277.2008.00659.x
    • KH Berger EC Kong J Dubnau T Tully MS Moore U Heberlein 2008 Ethanol sensitivity and tolerance in long-term memory mutants of Drosophila melanogaster Alcohol Clin Exp Res 32 895 908 18435628 1:CAS:528:DC%2BD1cXmvVShtbg%3D 10.1111/j.1530-0277.2008.00659.x
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 895-908
    • Berger, K.H.1    Kong, E.C.2    Dubnau, J.3    Tully, T.4    Moore, M.S.5    Heberlein, U.6
  • 14
    • 70349311756 scopus 로고    scopus 로고
    • An assay for evoked locomotor behavior in Drosophila reveals a role for integrins in ethanol sensitivity and rapid ethanol tolerance
    • 19645731 1:CAS:528:DC%2BD1MXhtlantrvL 10.1111/j.1530-0277.2009.01018.x
    • P Bhandari KS Kendler JC Bettinger AG Davies M Grotewiel 2009 An assay for evoked locomotor behavior in Drosophila reveals a role for integrins in ethanol sensitivity and rapid ethanol tolerance Alcohol Clin Exp Res 33 1794 1805 19645731 1:CAS:528:DC%2BD1MXhtlantrvL 10.1111/j.1530-0277.2009.01018.x
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1794-1805
    • Bhandari, P.1    Kendler, K.S.2    Bettinger, J.C.3    Davies, A.G.4    Grotewiel, M.5
  • 15
    • 0019426751 scopus 로고
    • Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method
    • 6269753 1:CAS:528:DyaL3MXls1Gqtbk%3D 10.1016/0092-8674(81)90176-8
    • PM Bingham R Lewis GM Rubin 1981 Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method Cell 25 693 704 6269753 1:CAS:528:DyaL3MXls1Gqtbk%3D 10.1016/0092-8674(81)90176-8
    • (1981) Cell , vol.25 , pp. 693-704
    • Bingham, P.M.1    Lewis, R.2    Rubin, G.M.3
  • 16
    • 0036403890 scopus 로고    scopus 로고
    • Abused drugs modulate RGS4 mRNA levels in the rat brain: Comparison between acute drug treatment and a drug challenge after chronic treatment
    • 12270694 1:CAS:528:DC%2BD38XmvFaisL8%3D 10.1006/nbdi.2002.0518
    • GB Bishop WE Cullinan E Curran HB Gutstein 2002 Abused drugs modulate RGS4 mRNA levels in the rat brain: comparison between acute drug treatment and a drug challenge after chronic treatment Neurobiol Dis 10 334 343 12270694 1:CAS:528:DC%2BD38XmvFaisL8%3D 10.1006/nbdi.2002.0518
    • (2002) Neurobiol Dis , vol.10 , pp. 334-343
    • Bishop, G.B.1    Cullinan, W.E.2    Curran, E.3    Gutstein, H.B.4
  • 17
    • 8644229424 scopus 로고    scopus 로고
    • Overexpression of the fyn-kinase gene reduces hypnotic sensitivity to ethanol in mice
    • 15531078 1:CAS:528:DC%2BD2cXpsFWiu78%3D 10.1016/j.neulet.2004.08.028
    • SL Boehm L Peden AW Jennings N Kojima RA Harris YA Blednov 2004 Overexpression of the fyn-kinase gene reduces hypnotic sensitivity to ethanol in mice Neurosci Lett 372 6 11 15531078 1:CAS:528:DC%2BD2cXpsFWiu78%3D 10.1016/j.neulet.2004.08.028
    • (2004) Neurosci Lett , vol.372 , pp. 6-11
    • Boehm, S.L.1    Peden, L.2    Jennings, A.W.3    Kojima, N.4    Harris, R.A.5    Blednov, Y.A.6
  • 18
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • 8223268 1:CAS:528:DyaK3sXlvFKrt7w%3D
    • AH Brand N Perrimon 1993 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes Development 118 401 415 8223268 1:CAS:528:DyaK3sXlvFKrt7w%3D
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 19
    • 0035122979 scopus 로고    scopus 로고
    • Regulation of the vesicular monoamine transporter-2: A novel mechanism for cocaine and other psychostimulants
    • JM Brown GR Hanson AE Fleckenstein 2001 Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants J Pharmacol Exp Ther 296 726 727
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 726-727
    • Brown, J.M.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 20
    • 77954202334 scopus 로고    scopus 로고
    • The synapsins: Key actors of synapse function and plasticity
    • 20438797 1:STN:280:DC%2BC3cnkvFGhuw%3D%3D 10.1016/j.pneurobio.2010.04.006
    • F Cesca P Baldelli F Valtorta F Benfenati 2010 The synapsins: key actors of synapse function and plasticity Prog Neurobiol 91 313 348 20438797 1:STN:280:DC%2BC3cnkvFGhuw%3D%3D 10.1016/j.pneurobio.2010.04.006
    • (2010) Prog Neurobiol , vol.91 , pp. 313-348
    • Cesca, F.1    Baldelli, P.2    Valtorta, F.3    Benfenati, F.4
  • 21
    • 32844455397 scopus 로고    scopus 로고
    • Overexpression of the Drosophila vesicular monoamine transporter increases motor activity and courtship but decreases the behavioral response to cocaine
    • 16189511 1:CAS:528:DC%2BD2MXhtlSksrnL 10.1038/sj.mp.4001742
    • HY Chang A Grygoruk ES Brooks LC Ackerson NT Maidment RJ Bainton DE Krantz 2006 Overexpression of the Drosophila vesicular monoamine transporter increases motor activity and courtship but decreases the behavioral response to cocaine Mol Psychiatry 11 99 113 16189511 1:CAS:528:DC%2BD2MXhtlSksrnL 10.1038/sj.mp.4001742
    • (2006) Mol Psychiatry , vol.11 , pp. 99-113
    • Chang, H.Y.1    Grygoruk, A.2    Brooks, E.S.3    Ackerson, L.C.4    Maidment, N.T.5    Bainton, R.J.6    Krantz, D.E.7
  • 22
    • 0037117494 scopus 로고    scopus 로고
    • Fighting fruit flies: A model system for the study of aggression
    • 11960020 1:CAS:528:DC%2BD38XjtFKltb0%3D 10.1073/pnas.082102599
    • S Chen AY Lee NM Bowens R Huber EA Kravitz 2002 Fighting fruit flies: a model system for the study of aggression Proc Natl Acad Sci USA 99 5664 5668 11960020 1:CAS:528:DC%2BD38XjtFKltb0%3D 10.1073/pnas.082102599
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5664-5668
    • Chen, S.1    Lee, A.Y.2    Bowens, N.M.3    Huber, R.4    Kravitz, E.A.5
  • 23
    • 34147097435 scopus 로고    scopus 로고
    • JWA as a functional molecule to regulate cancer cells migration via MAPK cascades and F-actin cytoskeleton
    • 17336041 1:CAS:528:DC%2BD2sXksV2mtbk%3D 10.1016/j.cellsig.2007.01.007
    • H Chen J Bai J Ye Z Liu R Chen W Mao A Li J Zhou 2007 JWA as a functional molecule to regulate cancer cells migration via MAPK cascades and F-actin cytoskeleton Cell Signal 19 1315 1327 17336041 1:CAS:528:DC%2BD2sXksV2mtbk%3D 10.1016/j.cellsig.2007.01.007
    • (2007) Cell Signal , vol.19 , pp. 1315-1327
    • Chen, H.1    Bai, J.2    Ye, J.3    Liu, Z.4    Chen, R.5    Mao, W.6    Li, A.7    Zhou, J.8
  • 25
    • 0022246189 scopus 로고
    • Latitudinal cline in Drosophila melanogaster for knockdown resistance to ethanol fumes and for rates of response to selection for further resistance
    • 1:CAS:528:DyaL2MXkvVGnur8%3D 10.2307/2408362
    • FM Cohan J-D Graf 1985 Latitudinal cline in Drosophila melanogaster for knockdown resistance to ethanol fumes and for rates of response to selection for further resistance Evolution 39 278 293 1:CAS:528:DyaL2MXkvVGnur8%3D 10.2307/2408362
    • (1985) Evolution , vol.39 , pp. 278-293
    • Cohan, F.M.1    Graf, J.-D.2
  • 26
    • 0033738280 scopus 로고    scopus 로고
    • Different sensitivity to ethanol in alcohol preferring sP and non-preferring sNP rats
    • G Colombo R Agabio MA Carai C Lobina M Pani R Reali, et al. 2000 Different sensitivity to ethanol in alcohol preferring sP and non-preferring sNP rats Alcohol Clin Exp Res 24 1602 1608
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1602-1608
    • Colombo, G.1    Agabio, R.2    Carai, M.A.3    Lobina, C.4    Pani, M.5    Reali, R.6
  • 27
    • 16644366598 scopus 로고    scopus 로고
    • Insulin signaling in the nervous system regulates ethanol intoxication in Drosophila melanogaster
    • 15592467 1:CAS:528:DC%2BD2MXhtFWgsg%3D%3D 10.1038/nn1363
    • AB Corl AR Rodan U Heberlein 2005 Insulin signaling in the nervous system regulates ethanol intoxication in Drosophila melanogaster Nat Neurosci 8 18 19 15592467 1:CAS:528:DC%2BD2MXhtFWgsg%3D%3D 10.1038/nn1363
    • (2005) Nat Neurosci , vol.8 , pp. 18-19
    • Corl, A.B.1    Rodan, A.R.2    Heberlein, U.3
  • 28
    • 67349117330 scopus 로고    scopus 로고
    • Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors
    • 19464045 1:CAS:528:DC%2BD1MXosVCltbc%3D 10.1016/j.cell.2009.03.020
    • AB Corl KH Berger G Ophir-Shohat J Gesch JA Simms S Bartlett U Heberlein 2009 Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors Cell 137 949 960 19464045 1:CAS:528: DC%2BD1MXosVCltbc%3D 10.1016/j.cell.2009.03.020
    • (2009) Cell , vol.137 , pp. 949-960
    • Corl, A.B.1    Berger, K.H.2    Ophir-Shohat, G.3    Gesch, J.4    Simms, J.A.5    Bartlett, S.6    Heberlein, U.7
  • 29
    • 27644535288 scopus 로고    scopus 로고
    • The slowpoke gene is necessary for rapid ethanol tolerance in Drosophila
    • 16269907 1:CAS:528:DC%2BD2MXhtFOhsLvF 10.1097/01.alc.0000183232.56788.62
    • RB Cowmeadow HR Krishnan NS Atkinson 2005 The slowpoke gene is necessary for rapid ethanol tolerance in Drosophila Alcohol Clin Exp Res 29 1777 1786 16269907 1:CAS:528:DC%2BD2MXhtFOhsLvF 10.1097/01.alc.0000183232.56788.62
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 1777-1786
    • Cowmeadow, R.B.1    Krishnan, H.R.2    Atkinson, N.S.3
  • 30
    • 33645961877 scopus 로고    scopus 로고
    • Ethanol tolerance caused by slowpoke induction in Drosophila
    • 16634842 1:CAS:528:DC%2BD28XlsVChu7s%3D 10.1111/j.1530-0277.2006.00087.x
    • RB Cowmeadow HR Krishnan A Ghezzi YM Al'Hasan YZ Wang NS Atkinson 2006 Ethanol tolerance caused by slowpoke induction in Drosophila Alcohol Clin Exp Res 30 745 753 16634842 1:CAS:528:DC%2BD28XlsVChu7s%3D 10.1111/j.1530-0277.2006. 00087.x
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 745-753
    • Cowmeadow, R.B.1    Krishnan, H.R.2    Ghezzi, A.3    Al'Hasan, Y.M.4    Wang, Y.Z.5    Atkinson, N.S.6
  • 31
    • 34447626327 scopus 로고    scopus 로고
    • Influence of PCPA and MDMA (ecstasy) on physiology, development and behavior in Drosophila melanogaster
    • 17650115 10.1111/j.1460-9568.2007.05655.x
    • S Dasari K Viele AC Turner RL Cooper 2007 Influence of PCPA and MDMA (ecstasy) on physiology, development and behavior in Drosophila melanogaster Eur J Neurosci 26 424 438 17650115 10.1111/j.1460-9568.2007.05655.x
    • (2007) Eur J Neurosci , vol.26 , pp. 424-438
    • Dasari, S.1    Viele, K.2    Turner, A.C.3    Cooper, R.L.4
  • 32
    • 79953792620 scopus 로고    scopus 로고
    • Traces of Drosophila memory
    • 21482352 1:CAS:528:DC%2BC3MXksFeltLo%3D 10.1016/j.neuron.2011.03.012
    • R Davis 2011 Traces of Drosophila memory Neuron 70 8 19 21482352 1:CAS:528:DC%2BC3MXksFeltLo%3D 10.1016/j.neuron.2011.03.012
    • (2011) Neuron , vol.70 , pp. 8-19
    • Davis, R.1
  • 33
    • 72449139682 scopus 로고    scopus 로고
    • Preferential ethanol consumption in Drosophila models features of addiction
    • 20005106 1:CAS:528:DC%2BD1MXhs1Wlt7vO 10.1016/j.cub.2009.10.070
    • AV Devineni U Heberlein 2009 Preferential ethanol consumption in Drosophila models features of addiction Curr Biol 19 2126 2132 20005106 1:CAS:528:DC%2BD1MXhs1Wlt7vO 10.1016/j.cub.2009.10.070
    • (2009) Curr Biol , vol.19 , pp. 2126-2132
    • Devineni, A.V.1    Heberlein, U.2
  • 34
    • 84856059319 scopus 로고    scopus 로고
    • The genetic relationships between ethanol preference, acute ethanol sensitivity and ethanol tolerance in Drosophila melanogaster
    • 21750412 1:CAS:528:DC%2BC38XhvVelurs%3D 10.4161/fly.5.3.16987
    • AV Devineni K McClure D Guarnieri A Corl F Wolf M Eddison U Heberlein 2011 The genetic relationships between ethanol preference, acute ethanol sensitivity and ethanol tolerance in Drosophila melanogaster Fly 5 191 199 21750412 1:CAS:528:DC%2BC38XhvVelurs%3D 10.4161/fly.5.3.16987
    • (2011) Fly , vol.5 , pp. 191-199
    • Devineni, A.V.1    McClure, K.2    Guarnieri, D.3    Corl, A.4    Wolf, F.5    Eddison, M.6    Heberlein, U.7
  • 36
    • 3242699712 scopus 로고    scopus 로고
    • An automated assay of the behavioral effects of cocaine injections in adult Drosophila
    • 15262059 1:CAS:528:DC%2BD2cXlsl2ht7g%3D 10.1016/j.jneumeth.2004.02.023
    • N Dimitrijevic S Dzitoyeva H Manev 2004 An automated assay of the behavioral effects of cocaine injections in adult Drosophila J Neurosci Methods 137 181 184 15262059 1:CAS:528:DC%2BD2cXlsl2ht7g%3D 10.1016/j.jneumeth.2004.02. 023
    • (2004) J Neurosci Methods , vol.137 , pp. 181-184
    • Dimitrijevic, N.1    Dzitoyeva, S.2    Manev, H.3
  • 37
    • 64249137056 scopus 로고    scopus 로고
    • Use-dependent plasticity in clock neurons regulates sleep need in Drosophila
    • 19342592 1:CAS:528:DC%2BD1MXjvVajs7g%3D 10.1126/science.1166657
    • JM Donlea N Ramanan PJ Shaw 2009 Use-dependent plasticity in clock neurons regulates sleep need in Drosophila Science 324 105 108 19342592 1:CAS:528:DC%2BD1MXjvVajs7g%3D 10.1126/science.1166657
    • (2009) Science , vol.324 , pp. 105-108
    • Donlea, J.M.1    Ramanan, N.2    Shaw, P.J.3
  • 38
    • 0036220788 scopus 로고    scopus 로고
    • Fermenting fruit and the historical ecology of ethanol ingestion: Is alcoholism in modern humans an evolutionary hangover?
    • 11964055 10.1046/j.1360-0443.2002.00002.x
    • R Dudley 2002 Fermenting fruit and the historical ecology of ethanol ingestion: is alcoholism in modern humans an evolutionary hangover? Addiction 97 381 388 11964055 10.1046/j.1360-0443.2002.00002.x
    • (2002) Addiction , vol.97 , pp. 381-388
    • Dudley, R.1
  • 39
    • 0038641709 scopus 로고    scopus 로고
    • γ-Aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: Adult RNA interference and pharmacological evidence
    • 12692303 1:CAS:528:DC%2BD3sXjs1yiur8%3D 10.1073/pnas.0830111100
    • S Dzitoyeva N Dimitrijevic H Manev 2003 γ-Aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence Proc Natl Acad Sci USA 100 5485 5490 12692303 1:CAS:528:DC%2BD3sXjs1yiur8%3D 10.1073/pnas.0830111100
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5485-5490
    • Dzitoyeva, S.1    Dimitrijevic, N.2    Manev, H.3
  • 40
    • 79958077316 scopus 로고    scopus 로고
    • Arouser reveals a role for synapse number in the regulation of ethanol sensitivity
    • 21658589 1:CAS:528:DC%2BC3MXnsVyrtLg%3D 10.1016/j.neuron.2011.03.030
    • M Eddison DJ Guarnieri L Cheng C-H Liu KG Moffat G Davis U Heberlein 2011 arouser reveals a role for synapse number in the regulation of ethanol sensitivity Neuron 70 979 990 21658589 1:CAS:528:DC%2BC3MXnsVyrtLg%3D 10.1016/j.neuron.2011.03.030
    • (2011) Neuron , vol.70 , pp. 979-990
    • Eddison, M.1    Guarnieri, D.J.2    Cheng, L.3    Liu, C.-H.4    Moffat, K.G.5    Davis, G.6    Heberlein, U.7
  • 42
    • 0015693891 scopus 로고
    • Effect of ethanol on biosynthesis of dopamine
    • 4145423 1:CAS:528:DyaE3sXltlarur0%3D 10.1111/j.1749-6632.1973.tb28266.x
    • AJ Friedhoff J Miller 1973 Effect of ethanol on biosynthesis of dopamine Ann N Y Acad Sci 215 183 186 4145423 1:CAS:528:DyaE3sXltlarur0%3D 10.1111/j.1749-6632.1973.tb28266.x
    • (1973) Ann N y Acad Sci , vol.215 , pp. 183-186
    • Friedhoff, A.J.1    Miller, J.2
  • 43
    • 3042796016 scopus 로고    scopus 로고
    • Notch signaling in Drosophila long-term memory formation
    • 15220476 1:CAS:528:DC%2BD2cXlvFOhsLg%3D 10.1073/pnas.0403497101
    • X Ge F Hannan Z Xie C Feng T Tully H Zhou Z Xie Y Zhong 2004 Notch signaling in Drosophila long-term memory formation Proc Natl Acad Sci USA 101 10172 10176 15220476 1:CAS:528:DC%2BD2cXlvFOhsLg%3D 10.1073/pnas.0403497101
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10172-10176
    • Ge, X.1    Hannan, F.2    Xie, Z.3    Feng, C.4    Tully, T.5    Zhou, H.6    Xie, Z.7    Zhong, Y.8
  • 44
    • 0027318065 scopus 로고
    • The biological basis of ethanol tolerance in Drosophila
    • 8359013 1:STN:280:DyaK3szmsFaluw%3D%3D 10.1016/0305-0491(93)90221-P
    • BW Geer PW Heinstra SW McKechnie 1993 The biological basis of ethanol tolerance in Drosophila Comp Biochem Physiol B 105 203 229 8359013 1:STN:280:DyaK3szmsFaluw%3D%3D 10.1016/0305-0491(93)90221-P
    • (1993) Comp Biochem Physiol B , vol.105 , pp. 203-229
    • Geer, B.W.1    Heinstra, P.W.2    McKechnie, S.W.3
  • 45
    • 16844384580 scopus 로고    scopus 로고
    • A "bottom-counting" video system for measuring cocaine-induced behaviors in Drosophila
    • 15817327 10.1016/S0076-6879(05)93044-9
    • R George K Lease J Burnette J Hirsh 2005 A "bottom-counting" video system for measuring cocaine-induced behaviors in Drosophila Methods Enzymol 393 841 851 15817327 10.1016/S0076-6879(05)93044-9
    • (2005) Methods Enzymol , vol.393 , pp. 841-851
    • George, R.1    Lease, K.2    Burnette, J.3    Hirsh, J.4
  • 46
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • 8628395 1:CAS:528:DyaK28XhtFKrurg%3D 10.1038/379606a0
    • B Giros M Jaber ST Jones RM Wightman MG Caron 1996 Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter Nature 379 606 612 8628395 1:CAS:528:DyaK28XhtFKrurg%3D 10.1038/379606a0
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.T.3    Wightman, R.M.4    Caron, M.G.5
  • 49
    • 0032915461 scopus 로고    scopus 로고
    • Loco encodes an RGS protein required for Drosophila glial differentiation
    • 10079238 1:CAS:528:DyaK1MXjtVeis78%3D
    • S Granderath A Stollework S Greig CS Goodman CJ O'Kane C Klambt 1999 loco encodes an RGS protein required for Drosophila glial differentiation Development 126 1781 1791 10079238 1:CAS:528:DyaK1MXjtVeis78%3D
    • (1999) Development , vol.126 , pp. 1781-1791
    • Granderath, S.1    Stollework, A.2    Greig, S.3    Goodman, C.S.4    O'Kane, C.J.5    Klambt, C.6
  • 50
    • 0034510553 scopus 로고    scopus 로고
    • Courtship in Drosophila
    • 11092827 1:CAS:528:DC%2BD3MXlvFKqtg%3D%3D 10.1146/annurev.genet.34.1.205
    • RJ Greenspan J-F Ferveur 2000 Courtship in Drosophila Annu Rev Genet 34 205 232 11092827 1:CAS:528:DC%2BD3MXlvFKqtg%3D%3D 10.1146/annurev.genet.34.1.205
    • (2000) Annu Rev Genet , vol.34 , pp. 205-232
    • Greenspan, R.J.1    Ferveur, J.-F.2
  • 51
    • 47049101429 scopus 로고    scopus 로고
    • An internal thermal sensor controlling temperature preference in Drosophila
    • 18548007 1:CAS:528:DC%2BD1cXot1ygsrw%3D 10.1038/nature07001
    • FN Hamada M Rosenzweig K Kang SR Pulver A Ghezzi TJ Jegla PA Garrity 2008 An internal thermal sensor controlling temperature preference in Drosophila Nature 454 217 220 18548007 1:CAS:528:DC%2BD1cXot1ygsrw%3D 10.1038/nature07001
    • (2008) Nature , vol.454 , pp. 217-220
    • Hamada, F.N.1    Rosenzweig, M.2    Kang, K.3    Pulver, S.R.4    Ghezzi, A.5    Jegla, T.J.6    Garrity, P.A.7
  • 52
    • 58149181578 scopus 로고    scopus 로고
    • Drosophila, a genetic model system to study cocaine-related behaviors: A review with focus on LIM-only proteins
    • 18694769 1:CAS:528:DC%2BD1MXhsVKgsA%3D%3D 10.1016/j.neuropharm.2008.07. 023
    • U Heberlein LT Tsai D Kapfhamer AW Lasek 2009 Drosophila, a genetic model system to study cocaine-related behaviors: a review with focus on LIM-only proteins Neuropharmacology 56 Suppl 1 97 106 18694769 1:CAS:528: DC%2BD1MXhsVKgsA%3D%3D 10.1016/j.neuropharm.2008.07.023
    • (2009) Neuropharmacology , vol.56 , Issue.SUPPL. 1 , pp. 97-106
    • Heberlein, U.1    Tsai, L.T.2    Kapfhamer, D.3    Lasek, A.W.4
  • 54
    • 0021634270 scopus 로고
    • Olfactory response and resource utilization in Drosophila-interspecific comparison
    • 10.1111/j.1095-8312.1984.tb00798.x
    • AA Hoffmann PA Parsons 1984 Olfactory response and resource utilization in Drosophila-interspecific comparison Biol J Linnean Soc 22 43 53 10.1111/j.1095-8312.1984.tb00798.x
    • (1984) Biol J Linnean Soc , vol.22 , pp. 43-53
    • Hoffmann, A.A.1    Parsons, P.A.2
  • 55
    • 0037266903 scopus 로고    scopus 로고
    • More genes in vertebrates?
    • 12836687 1:CAS:528:DC%2BD3sXhsFKqsb4%3D 10.1023/A:1022656931587
    • PW Holland 2003 More genes in vertebrates? J Struct Funct Genomics 3 75 84 12836687 1:CAS:528:DC%2BD3sXhsFKqsb4%3D 10.1023/A:1022656931587
    • (2003) J Struct Funct Genomics , vol.3 , pp. 75-84
    • Holland, P.W.1
  • 57
    • 85027932192 scopus 로고    scopus 로고
    • A Drosophila model for ethanol reward
    • 21499254 1:CAS:528:DC%2BC3MXkslCmsbY%3D 10.1038/nn.2805
    • KR Kaun R Azanchi Z Maung J Hirsh U Heberlein 2011 A Drosophila model for ethanol reward Nat Neurosci 14 612 619 21499254 1:CAS:528:DC%2BC3MXkslCmsbY%3D 10.1038/nn.2805
    • (2011) Nat Neurosci , vol.14 , pp. 612-619
    • Kaun, K.R.1    Azanchi, R.2    Maung, Z.3    Hirsh, J.4    Heberlein, U.5
  • 58
    • 78751522556 scopus 로고    scopus 로고
    • Drosophila tao controls mushroom body development and ethanol-stimulated behavior through par-1
    • 21248138 1:CAS:528:DC%2BC3MXhsVemtLs%3D 10.1523/JNEUROSCI.4416-10.2011
    • I King LT Tsai R Pflanz A Voigt S Lee H Jackle B Lu U Heberlein 2011 Drosophila tao controls mushroom body development and ethanol-stimulated behavior through par-1 J Neurosci 31 1139 1148 21248138 1:CAS:528: DC%2BC3MXhsVemtLs%3D 10.1523/JNEUROSCI.4416-10.2011
    • (2011) J Neurosci , vol.31 , pp. 1139-1148
    • King, I.1    Tsai, L.T.2    Pflanz, R.3    Voigt, A.4    Lee, S.5    Jackle, H.6    Lu, B.7    Heberlein, U.8
  • 59
    • 0035072239 scopus 로고    scopus 로고
    • Conditional modification of behavior in Drosophila by targeted expression of a temperature-sensitive shibire allele in defined neurons
    • 11291099 1:CAS:528:DC%2BD3MXjsVWlt78%3D 10.1002/neu.1018
    • T Kitamoto 2001 Conditional modification of behavior in Drosophila by targeted expression of a temperature-sensitive shibire allele in defined neurons J Neurobiol 47 81 92 11291099 1:CAS:528:DC%2BD3MXjsVWlt78%3D 10.1002/neu.1018
    • (2001) J Neurobiol , vol.47 , pp. 81-92
    • Kitamoto, T.1
  • 60
    • 0036082795 scopus 로고    scopus 로고
    • Integrated channel plasticity contributes to alcohol tolerance in neurohypophysial terminals
    • 12065764 1:CAS:528:DC%2BD38Xlt1KqtbY%3D 10.1124/mol.62.1.135
    • TK Knott AM Dopico G Dayanithi J Lemos SN Treistman 2002 Integrated channel plasticity contributes to alcohol tolerance in neurohypophysial terminals Mol Pharmacol 62 135 142 12065764 1:CAS:528:DC%2BD38Xlt1KqtbY%3D 10.1124/mol.62.1.135
    • (2002) Mol Pharmacol , vol.62 , pp. 135-142
    • Knott, T.K.1    Dopico, A.M.2    Dayanithi, G.3    Lemos, J.4    Treistman, S.N.5
  • 61
    • 74549144994 scopus 로고    scopus 로고
    • Ethanol-regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila
    • 19951294 1:CAS:528:DC%2BC3cXit1Wmtbg%3D 10.1111/j.1530-0277.2009.01093.x
    • EC Kong L Allouche PA Chapot K Vranizan MS Moore U Heberlein FW Wolf 2010 Ethanol-regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila Alcohol Clin Exp Res 34 302 316 19951294 1:CAS:528:DC%2BC3cXit1Wmtbg%3D 10.1111/j.1530-0277.2009.01093.x
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 302-316
    • Kong, E.C.1    Allouche, L.2    Chapot, P.A.3    Vranizan, K.4    Moore, M.S.5    Heberlein, U.6    Wolf, F.W.7
  • 62
    • 77956157366 scopus 로고    scopus 로고
    • A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila
    • 20376353 10.1371/journal.pone.0009954 1:CAS:528:DC%2BC3cXksFylurc%3D
    • EC Kong K Woo L Haiyan T Lebestky N Mayer MR Sniffen U Heberlein RJ Bainton J Hirsh FW Wolf 2010 A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila PLoS ONE 5 e9954 20376353 10.1371/journal.pone.0009954 1:CAS:528:DC%2BC3cXksFylurc%3D
    • (2010) PLoS ONE , vol.5 , pp. 9954
    • Kong, E.C.1    Woo, K.2    Haiyan, L.3    Lebestky, T.4    Mayer, N.5    Sniffen, M.R.6    Heberlein, U.7    Bainton, R.J.8    Hirsh, J.9    Wolf, F.W.10
  • 63
    • 4644342311 scopus 로고    scopus 로고
    • A role for GABA mechanisms in the motivational effects of alcohol
    • 15451394 1:CAS:528:DC%2BD2cXnvV2qsr8%3D 10.1016/j.bcp.2004.07.031
    • GF Koob 2004 A role for GABA mechanisms in the motivational effects of alcohol Biochem Pharmacol 68 1515 1525 15451394 1:CAS:528:DC%2BD2cXnvV2qsr8%3D 10.1016/j.bcp.2004.07.031
    • (2004) Biochem Pharmacol , vol.68 , pp. 1515-1525
    • Koob, G.F.1
  • 64
    • 0030758555 scopus 로고    scopus 로고
    • The neurobiology of drug addiction
    • 1:CAS:528:DyaK2sXmtVGgsb4%3D
    • GF Koob EJ Nestler 1997 The neurobiology of drug addiction J Neurophychiatry Clin Neurosci 9 482 497 1:CAS:528:DyaK2sXmtVGgsb4%3D
    • (1997) J Neurophychiatry Clin Neurosci , vol.9 , pp. 482-497
    • Koob, G.F.1    Nestler, E.J.2
  • 65
    • 33845880917 scopus 로고    scopus 로고
    • Sequential use of mushroom body neuron subsets during Drosophila odor memory processing
    • 17196534 1:CAS:528:DC%2BD2sXpsFSmsg%3D%3D 10.1016/j.neuron.2006.11.021
    • MJ Krashes AC Keene B Leung JD Armstrong S Waddell 2007 Sequential use of mushroom body neuron subsets during Drosophila odor memory processing Neuron 53 103 115 17196534 1:CAS:528:DC%2BD2sXpsFSmsg%3D%3D 10.1016/j.neuron.2006.11.021
    • (2007) Neuron , vol.53 , pp. 103-115
    • Krashes, M.J.1    Keene, A.C.2    Leung, B.3    Armstrong, J.D.4    Waddell, S.5
  • 66
  • 67
    • 0029993734 scopus 로고    scopus 로고
    • Genetic differences in tolerance and sensitization to the sedative/hypnotic effects of alcohol
    • 8866959 1:CAS:528:DyaK28XhsVCltLk%3D 10.1016/0091-3057(95)02055-1
    • DL Kurtz RB Stewart M Zweifel T-K Li JC Froehlich 1996 Genetic differences in tolerance and sensitization to the sedative/hypnotic effects of alcohol Pharmacol Biochem Behav 53 585 591 8866959 1:CAS:528:DyaK28XhsVCltLk%3D 10.1016/0091-3057(95)02055-1
    • (1996) Pharmacol Biochem Behav , vol.53 , pp. 585-591
    • Kurtz, D.L.1    Stewart, R.B.2    Zweifel, M.3    Li, T.-K.4    Froehlich, J.C.5
  • 68
    • 45849092961 scopus 로고    scopus 로고
    • Genetic dissociation of ethanol sensitivity and memory formation in Drosophila melanogaster
    • 18430923 1:CAS:528:DC%2BD1cXmt1eltbg%3D 10.1534/genetics.107.084582
    • H LaFerriere DJ Guarnieri D Sitaraman D Diegelmann U Heberlein T Zars 2008 Genetic dissociation of ethanol sensitivity and memory formation in Drosophila melanogaster Genetics 178 1895 1902 18430923 1:CAS:528: DC%2BD1cXmt1eltbg%3D 10.1534/genetics.107.084582
    • (2008) Genetics , vol.178 , pp. 1895-1902
    • Laferriere, H.1    Guarnieri, D.J.2    Sitaraman, D.3    Diegelmann, D.4    Heberlein, U.5    Zars, T.6
  • 69
    • 33745742246 scopus 로고    scopus 로고
    • Genetic mosaic with dual binary transcriptional systems in Drosophila
    • 16582903 1:CAS:528:DC%2BD28XjvFaqsL0%3D 10.1038/nn1681
    • SL Lai T Lee 2006 Genetic mosaic with dual binary transcriptional systems in Drosophila Nat Neurosci 9 703 709 16582903 1:CAS:528:DC%2BD28XjvFaqsL0%3D 10.1038/nn1681
    • (2006) Nat Neurosci , vol.9 , pp. 703-709
    • Lai, S.L.1    Lee, T.2
  • 70
    • 78649615166 scopus 로고    scopus 로고
    • Lmo4 in the nucleus accumbens regulates cocaine sensitivity
    • 20618444 1:CAS:528:DC%2BC3cXhsVagtLrI 10.1111/j.1601-183X.2010.00620.x
    • AW Lasek D Kapfhamer V Kharazia J Gesch F Giorgetti U Heberlein 2010 Lmo4 in the nucleus accumbens regulates cocaine sensitivity Genes Brain Behav 9 817 824 20618444 1:CAS:528:DC%2BC3cXhsVagtLrI 10.1111/j.1601-183X.2010.00620.x
    • (2010) Genes Brain Behav , vol.9 , pp. 817-824
    • Lasek, A.W.1    Kapfhamer, D.2    Kharazia, V.3    Gesch, J.4    Giorgetti, F.5    Heberlein, U.6
  • 71
    • 79960657267 scopus 로고    scopus 로고
    • Lmo genes regulate behavioral responses to ethanol in Drosophila melanogaster and the mouse
    • 21599714 1:CAS:528:DC%2BC3MXht1OisbrK
    • AW Lasek F Giorgetti KH Berger S Tayor U Heberlein 2011 Lmo genes regulate behavioral responses to ethanol in Drosophila melanogaster and the mouse Alcohol Clin Exp Res 35 1600 1606 21599714 1:CAS:528:DC%2BC3MXht1OisbrK
    • (2011) Alcohol Clin Exp Res , vol.35 , pp. 1600-1606
    • Lasek, A.W.1    Giorgetti, F.2    Berger, K.H.3    Tayor, S.4    Heberlein, U.5
  • 73
    • 34249049622 scopus 로고    scopus 로고
    • The F-actin-microtubule crosslinker Shot is a platform for Krasavietz-mediated translational regulation of midline axon repulsion
    • 17409115 1:CAS:528:DC%2BD2sXmt1aiu74%3D 10.1242/dev.02842
    • S Lee M Nahm M Lee M Kwon E Kim AS Zadeh H Cao HJ Kim ZH Lee SB Oh PA Kolodziej S Lee 2007 The F-actin-microtubule crosslinker Shot is a platform for Krasavietz-mediated translational regulation of midline axon repulsion Development 134 1767 1777 17409115 1:CAS:528:DC%2BD2sXmt1aiu74%3D 10.1242/dev.02842
    • (2007) Development , vol.134 , pp. 1767-1777
    • Lee, S.1    Nahm, M.2    Lee, M.3    Kwon, M.4    Kim, E.5    Zadeh, A.S.6    Cao, H.7    Kim, H.J.8    Lee, Z.H.9    Oh, S.B.10    Kolodziej, P.A.11    Lee, S.12
  • 74
    • 0034708147 scopus 로고    scopus 로고
    • Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster
    • 10704417 1:CAS:528:DC%2BD3cXhsFKrtrY%3D 10.1016/S0960-9822(00)00340-7
    • H Li S Chaney IJ Roberts M Forte J Hirsh 2000 Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster Curr Biol 10 211 214 10704417 1:CAS:528: DC%2BD3cXhsFKrtrY%3D 10.1016/S0960-9822(00)00340-7
    • (2000) Curr Biol , vol.10 , pp. 211-214
    • Li, H.1    Chaney, S.2    Roberts, I.J.3    Forte, M.4    Hirsh, J.5
  • 75
    • 51749101897 scopus 로고    scopus 로고
    • The Drosophila homolog of jwa is required for ethanol tolerance
    • 18503079 1:CAS:528:DC%2BD1cXhtF2rtbnN
    • C Li X Zhao C Xingjiang D Chu J Chen J Zhou 2008 The Drosophila homolog of jwa is required for ethanol tolerance Alcohol Alcohol 43 529 536 18503079 1:CAS:528:DC%2BD1cXhtF2rtbnN
    • (2008) Alcohol Alcohol , vol.43 , pp. 529-536
    • Li, C.1    Zhao, X.2    Xingjiang, C.3    Chu, D.4    Chen, J.5    Zhou, J.6
  • 76
    • 0033694834 scopus 로고    scopus 로고
    • Ion channels and synaptic organization: Analysis of the Drosophila genome
    • 10798390 1:CAS:528:DC%2BD3cXjtFSktr4%3D 10.1016/S0896-6273(00)81135-6
    • JT Littleton B Ganetzky 2000 Ion channels and synaptic organization: analysis of the Drosophila genome Neuron 26 35 43 10798390 1:CAS:528: DC%2BD3cXjtFSktr4%3D 10.1016/S0896-6273(00)81135-6
    • (2000) Neuron , vol.26 , pp. 35-43
    • Littleton, J.T.1    Ganetzky, B.2
  • 77
    • 0033679290 scopus 로고    scopus 로고
    • A genome-wide search for synaptic vesicle proteins in Drosophila
    • 10798391 1:CAS:528:DC%2BD3cXjtFSktr8%3D 10.1016/S0896-6273(00)81136-8
    • TE Lloyd P Verstreken EJ Ostrin A Phillippi O Lichtarge, et al. 2000 A genome-wide search for synaptic vesicle proteins in Drosophila Neuron 26 45 50 10798391 1:CAS:528:DC%2BD3cXjtFSktr8%3D 10.1016/S0896-6273(00)81136-8
    • (2000) Neuron , vol.26 , pp. 45-50
    • Lloyd, T.E.1    Verstreken, P.2    Ostrin, E.J.3    Phillippi, A.4    Lichtarge, O.5
  • 78
    • 33750508956 scopus 로고    scopus 로고
    • Refining spatial manipulation of neuronal function by combinatorial restriction of transgene expression
    • 17088209 1:CAS:528:DC%2BD28Xht1KhtbjL 10.1016/j.neuron.2006.08.028
    • H Luan NC Peabody CR Vinson BJ White 2006 Refining spatial manipulation of neuronal function by combinatorial restriction of transgene expression Neuron 52 425 436 17088209 1:CAS:528:DC%2BD28Xht1KhtbjL 10.1016/j.neuron.2006.08.028
    • (2006) Neuron , vol.52 , pp. 425-436
    • Luan, H.1    Peabody, N.C.2    Vinson, C.R.3    White, B.J.4
  • 79
    • 0033197791 scopus 로고    scopus 로고
    • Central complex structures are required for the maintenance of locomotor activity in Drosophila melanogaster
    • 10573866 1:STN:280:DC%2BD3c%2FktFWlsw%3D%3D 10.1007/s003590050387
    • JR Martin T Raabe M Heisenberg 1999 Central complex structures are required for the maintenance of locomotor activity in Drosophila melanogaster J Comp Physiol A 185 277 288 10573866 1:STN:280:DC%2BD3c%2FktFWlsw%3D%3D 10.1007/s003590050387
    • (1999) J Comp Physiol A , vol.185 , pp. 277-288
    • Martin, J.R.1    Raabe, T.2    Heisenberg, M.3
  • 80
    • 67649983118 scopus 로고    scopus 로고
    • The tau of MARK: A polarized view of the cytoskeleton
    • 19559622 1:CAS:528:DC%2BD1MXosVylsrk%3D 10.1016/j.tibs.2009.03.008
    • D Matenia EM Mandelkow 2009 The tau of MARK: a polarized view of the cytoskeleton Trends Biochem Sci 34 332 342 19559622 1:CAS:528: DC%2BD1MXosVylsrk%3D 10.1016/j.tibs.2009.03.008
    • (2009) Trends Biochem Sci , vol.34 , pp. 332-342
    • Matenia, D.1    Mandelkow, E.M.2
  • 81
    • 0032466081 scopus 로고    scopus 로고
    • Animal models of alcoholism: Neurobiology of high alcohol-drinking behavior in rodents
    • 10348615 1:STN:280:DyaK1M3ntVWguw%3D%3D
    • WJ McBride TK Li 1998 Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents Crit Rev Neurobiol 12 339 369 10348615 1:STN:280:DyaK1M3ntVWguw%3D%3D
    • (1998) Crit Rev Neurobiol , vol.12 , pp. 339-369
    • McBride, W.J.1    Li, T.K.2
  • 82
    • 0032518346 scopus 로고    scopus 로고
    • Stereotypic behavioral responses to free-base cocaine and the development of behavioral sensitization in Drosophila
    • 9427649 1:CAS:528:DyaK1cXlt12hsA%3D%3D 10.1016/S0960-9822(98)70041-7
    • C McClung J Hirsh 1998 Stereotypic behavioral responses to free-base cocaine and the development of behavioral sensitization in Drosophila Curr Biol 8 109 112 9427649 1:CAS:528:DyaK1cXlt12hsA%3D%3D 10.1016/S0960-9822(98)70041-7
    • (1998) Curr Biol , vol.8 , pp. 109-112
    • McClung, C.1    Hirsh, J.2
  • 84
    • 0345168202 scopus 로고    scopus 로고
    • Spatiotemporal rescue of memory dysfunction in Drosophila
    • 14657498 1:CAS:528:DC%2BD3sXpsVWnsrg%3D 10.1126/science.1089035
    • SE McGuire PT Le AJ Osborn K Matsumoto RL Davis 2003 Spatiotemporal rescue of memory dysfunction in Drosophila Science 302 1765 1768 14657498 1:CAS:528:DC%2BD3sXpsVWnsrg%3D 10.1126/science.1089035
    • (2003) Science , vol.302 , pp. 1765-1768
    • McGuire, S.E.1    Le, P.T.2    Osborn, A.J.3    Matsumoto, K.4    Davis, R.L.5
  • 85
    • 0001599478 scopus 로고
    • Alcohol tolerance-ecological parameter in relative success of Drosophila melanogaster and Drosphila simulans
    • 10.1007/BF00345738
    • JA McKenzie P Parsons 1972 Alcohol tolerance-ecological parameter in relative success of Drosophila melanogaster and Drosphila simulans Oecologia 10 373 388 10.1007/BF00345738
    • (1972) Oecologia , vol.10 , pp. 373-388
    • McKenzie, J.A.1    Parsons, P.2
  • 86
    • 0035131643 scopus 로고    scopus 로고
    • B receptors from Drosophila
    • 11168554 1:STN:280:DC%2BD3M3isFyhsg%3D%3D 10.1046/j.1460-9568.2001.01410. x
    • B receptors from Drosophila Eur J Neurosci 13 477 486 11168554 1:STN:280:DC%2BD3M3isFyhsg%3D%3D 10.1046/j.1460-9568.2001.01410.x
    • (2001) Eur J Neurosci , vol.13 , pp. 477-486
    • Mezler, M.1    Muller, T.2    Raming, K.3
  • 87
    • 0032511188 scopus 로고    scopus 로고
    • Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway
    • 9635429 1:CAS:528:DyaK1cXjvFKqsLk%3D 10.1016/S0092-8674(00)81205-2
    • MS Moore J DeZazzo AY Luk T Tully CM Singh U Heberlein 1998 Ethanol intoxication in Drosophila: genetic and pharmacological evidence for regulation by the cAMP signaling pathway Cell 93 997 1007 9635429 1:CAS:528: DyaK1cXjvFKqsLk%3D 10.1016/S0092-8674(00)81205-2
    • (1998) Cell , vol.93 , pp. 997-1007
    • Moore, M.S.1    Dezazzo, J.2    Luk, A.Y.3    Tully, T.4    Singh, C.M.5    Heberlein, U.6
  • 88
    • 77749258491 scopus 로고    scopus 로고
    • Subjective response to alcohol: A critical review of the literature
    • 20028359 10.1111/j.1530-0277.2009.01103.x
    • ME Morean WR Corbin 2010 Subjective response to alcohol: a critical review of the literature Alcohol Clin Exp Res 34 385 395 20028359 10.1111/j.1530-0277.2009.01103.x
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 385-395
    • Morean, M.E.1    Corbin, W.R.2
  • 89
    • 33750838273 scopus 로고    scopus 로고
    • Transcriptional response to alcohol exposure in Drosophila melanogaster
    • 17054780 10.1186/gb-2006-7-10-r95 1:CAS:528:DC%2BD28Xht1eitr7J
    • TV Morozova RR Anholt TF Mackay 2006 Transcriptional response to alcohol exposure in Drosophila melanogaster Genome Biol 7 R95 17054780 10.1186/gb-2006-7-10-r95 1:CAS:528:DC%2BD28Xht1eitr7J
    • (2006) Genome Biol , vol.7 , pp. 95
    • Morozova, T.V.1    Anholt, R.R.2    MacKay, T.F.3
  • 90
    • 42949142215 scopus 로고    scopus 로고
    • Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster
    • 17973985 10.1186/gb-2007-8-10-r231 1:CAS:528:DC%2BD1cXhs1CntbY%3D
    • TV Morozova RR Anholt TF Mackay 2007 Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster Genome Biol 8 R231 17973985 10.1186/gb-2007-8-10-r231 1:CAS:528:DC%2BD1cXhs1CntbY%3D
    • (2007) Genome Biol , vol.8 , pp. 231
    • Morozova, T.V.1    Anholt, R.R.2    MacKay, T.F.3
  • 91
    • 0026790115 scopus 로고
    • Aminergic neurons in the brain of blowflies and Drosophila: Dopamine- and tyrosine hydroxylase-immunoreactive neurons and their relationship with putative histaminergic neurons
    • 1346506 1:STN:280:DyaK387js1CitA%3D%3D 10.1007/BF00318701
    • DR Nassel K Elekes 1992 Aminergic neurons in the brain of blowflies and Drosophila: dopamine- and tyrosine hydroxylase-immunoreactive neurons and their relationship with putative histaminergic neurons Cell Tissue Res 267 147 167 1346506 1:STN:280:DyaK387js1CitA%3D%3D 10.1007/BF00318701
    • (1992) Cell Tissue Res , vol.267 , pp. 147-167
    • Nassel, D.R.1    Elekes, K.2
  • 92
    • 27644454004 scopus 로고    scopus 로고
    • Is there a common molecular pathway for addiction?
    • 16251986 1:CAS:528:DC%2BD2MXhtFCrurbP 10.1038/nn1578
    • EJ Nestler 2005 Is there a common molecular pathway for addiction? Nat Neurosci 8 1445 1449 16251986 1:CAS:528:DC%2BD2MXhtFCrurbP 10.1038/nn1578
    • (2005) Nat Neurosci , vol.8 , pp. 1445-1449
    • Nestler, E.J.1
  • 93
    • 46249133489 scopus 로고    scopus 로고
    • Analysis of a spatial orientation memory in Drosophila
    • 18509336 1:CAS:528:DC%2BD1cXnslGksLg%3D 10.1038/nature07003
    • K Neuser T Triphan M Mronz B Poeck R Strauss 2008 Analysis of a spatial orientation memory in Drosophila Nature 453 1244 1247 18509336 1:CAS:528:DC%2BD1cXnslGksLg%3D 10.1038/nature07003
    • (2008) Nature , vol.453 , pp. 1244-1247
    • Neuser, K.1    Triphan, T.2    Mronz, M.3    Poeck, B.4    Strauss, R.5
  • 94
    • 79958272914 scopus 로고    scopus 로고
    • Visual place learning in Drosophila melanogaster
    • 21654803 1:CAS:528:DC%2BC3MXntFKrtrs%3D 10.1038/nature10131
    • TA Ofstad CS Zuker MB Reiser 2011 Visual place learning in Drosophila melanogaster Nature 474 204 207 21654803 1:CAS:528:DC%2BC3MXntFKrtrs%3D 10.1038/nature10131
    • (2011) Nature , vol.474 , pp. 204-207
    • Ofstad, T.A.1    Zuker, C.S.2    Reiser, M.B.3
  • 95
    • 0034617078 scopus 로고    scopus 로고
    • Type II cAMP-dependent protein kinase-deficient Drosophila are viable but show developmental, circadian, and drug response phenotypes
    • 10781603 1:CAS:528:DC%2BD3cXkvVyhsLk%3D 10.1074/jbc.M002460200
    • SK Park SA Sedore C Cronmiller J Hirsh 2000 Type II cAMP-dependent protein kinase-deficient Drosophila are viable but show developmental, circadian, and drug response phenotypes J Biol Chem 275 20588 20596 10781603 1:CAS:528:DC%2BD3cXkvVyhsLk%3D 10.1074/jbc.M002460200
    • (2000) J Biol Chem , vol.275 , pp. 20588-20596
    • Park, S.K.1    Sedore, S.A.2    Cronmiller, C.3    Hirsh, J.4
  • 97
    • 0032200291 scopus 로고    scopus 로고
    • Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors
    • 10196569 1:CAS:528:DyaK1MXitVCns70%3D 10.1038/2843
    • TJ Phillips KJ Brown S Burkhard-Kasch CD Wenger MS Kelly M Rubinstein, et al. 1998 Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors Nat Neurosci 1 610 615 10196569 1:CAS:528:DyaK1MXitVCns70%3D 10.1038/2843
    • (1998) Nat Neurosci , vol.1 , pp. 610-615
    • Phillips, T.J.1    Brown, K.J.2    Burkhard-Kasch, S.3    Wenger, C.D.4    Kelly, M.S.5    Rubinstein, M.6
  • 98
    • 23944468293 scopus 로고    scopus 로고
    • Goal-driven behavioral adaptations in gap-climbing Drosophila
    • 16111941 1:CAS:528:DC%2BD2MXos1ajtro%3D 10.1016/j.cub.2005.07.022
    • S Pick R Strauss 2005 Goal-driven behavioral adaptations in gap-climbing Drosophila Curr Biol 15 1473 1478 16111941 1:CAS:528:DC%2BD2MXos1ajtro%3D 10.1016/j.cub.2005.07.022
    • (2005) Curr Biol , vol.15 , pp. 1473-1478
    • Pick, S.1    Strauss, R.2
  • 99
    • 0028867333 scopus 로고
    • The heat shock and ethanol stress responses of yeast exhibit extensive similarity and functional overlap
    • 8586257 1:CAS:528:DyaK2MXpvVyqur4%3D 10.1111/j.1574-6968.1995.tb07925.x
    • PW Piper 1995 The heat shock and ethanol stress responses of yeast exhibit extensive similarity and functional overlap FEMS Microbiol Lett 134 121 127 8586257 1:CAS:528:DyaK2MXpvVyqur4%3D 10.1111/j.1574-6968.1995.tb07925.x
    • (1995) FEMS Microbiol Lett , vol.134 , pp. 121-127
    • Piper, P.W.1
  • 100
    • 0035252333 scopus 로고    scopus 로고
    • Scabrous complexes with Notch to mediate boundary formation
    • 11214322 1:STN:280:DC%2BD3M7islSntQ%3D%3D 10.1038/35054566
    • PA Powell C Wesley S Spencer RL Cagan 2001 Scabrous complexes with Notch to mediate boundary formation Nature 409 626 630 11214322 1:STN:280: DC%2BD3M7islSntQ%3D%3D 10.1038/35054566
    • (2001) Nature , vol.409 , pp. 626-630
    • Powell, P.A.1    Wesley, C.2    Spencer, S.3    Cagan, R.L.4
  • 101
    • 0021020713 scopus 로고
    • Effect of cocaine on rat brain enzymes
    • 6141775 1:CAS:528:DyaL2cXmtFOgug%3D%3D
    • S Pradhan 1983 Effect of cocaine on rat brain enzymes Arch Int Pharmacodyn Ther 266 221 228 6141775 1:CAS:528:DyaL2cXmtFOgug%3D%3D
    • (1983) Arch Int Pharmacodyn Ther , vol.266 , pp. 221-228
    • Pradhan, S.1
  • 102
    • 1242342184 scopus 로고    scopus 로고
    • Notch is required for long-term memory in Drosophila
    • 10.1073/pnas.0308259100 1:CAS:528:DC%2BD2cXhsFaqtbg%3D
    • A Presente RS Boyles CN Serway S deBelle A Andres 2004 Notch is required for long-term memory in Drosophila Proc Natl Acad Sci USA 101 1746 1768 10.1073/pnas.0308259100 1:CAS:528:DC%2BD2cXhsFaqtbg%3D
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1746-1768
    • Presente, A.1    Boyles, R.S.2    Serway, C.N.3    Debelle, S.4    Andres, A.5
  • 103
    • 66349129337 scopus 로고    scopus 로고
    • Temporal dynamics of neuronal activation by Channelrhodopsin-2 and TRPA1 determine behavioral output in Drosophila larvae
    • 19339465 10.1152/jn.00071.2009
    • SR Pulver SL Pashkovski NJ Hornstein PA Garrity LC Griffith 2009 Temporal dynamics of neuronal activation by Channelrhodopsin-2 and TRPA1 determine behavioral output in Drosophila larvae J Neurophysiol 101 3075 3088 19339465 10.1152/jn.00071.2009
    • (2009) J Neurophysiol , vol.101 , pp. 3075-3088
    • Pulver, S.R.1    Pashkovski, S.L.2    Hornstein, N.J.3    Garrity, P.A.4    Griffith, L.C.5
  • 104
    • 0000668803 scopus 로고
    • Conditioned behavior in Drosophila melanogaster
    • 4207071 1:STN:280:DyaE2c7kt1KktQ%3D%3D 10.1073/pnas.71.3.708
    • WG Quinn WA Harris S Benzer 1974 Conditioned behavior in Drosophila melanogaster Proc Natl Acad Sci USA 71 708 712 4207071 1:STN:280: DyaE2c7kt1KktQ%3D%3D 10.1073/pnas.71.3.708
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 708-712
    • Quinn, W.G.1    Harris, W.A.2    Benzer, S.3
  • 105
    • 0034837386 scopus 로고    scopus 로고
    • A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster
    • 11381037 1:CAS:528:DC%2BD3MXkt12ru7s%3D 10.1101/gr.169101
    • LT Reiter L Potocki S Chien M Gribskov E Bier 2001 A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster Genome Res 11 1114 1125 11381037 1:CAS:528:DC%2BD3MXkt12ru7s%3D 10.1101/gr.169101
    • (2001) Genome Res , vol.11 , pp. 1114-1125
    • Reiter, L.T.1    Potocki, L.2    Chien, S.3    Gribskov, M.4    Bier, E.5
  • 106
    • 0033599009 scopus 로고    scopus 로고
    • A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila
    • 10619432 1:CAS:528:DC%2BD3cXislSltQ%3D%3D 10.1016/S0092-8674(00)81676-1
    • SC Renn JH Park M Rosbash JC Hall PH Taghert 1999 A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila Cell 99 791 802 10619432 1:CAS:528:DC%2BD3cXislSltQ%3D%3D 10.1016/S0092-8674(00)81676-1
    • (1999) Cell , vol.99 , pp. 791-802
    • Renn, S.C.1    Park, J.H.2    Rosbash, M.3    Hall, J.C.4    Taghert, P.H.5
  • 108
    • 33749058095 scopus 로고    scopus 로고
    • Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms
    • 17018286 1:CAS:528:DC%2BD28XhtFSitrzP 10.1016/j.cell.2006.09.010
    • A Rothenfluh RJ Threlkeld RJ Bainton LT Tsai AW Lasek U Heberlein 2006 Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms Cell 127 199 211 17018286 1:CAS:528:DC%2BD28XhtFSitrzP 10.1016/j.cell.2006.09.010
    • (2006) Cell , vol.127 , pp. 199-211
    • Rothenfluh, A.1    Threlkeld, R.J.2    Bainton, R.J.3    Tsai, L.T.4    Lasek, A.W.5    Heberlein, U.6
  • 109
    • 0019945644 scopus 로고
    • Genetic transformation of Drosophila with transposable element vectors
    • 6289436 1:CAS:528:DyaL3sXhtFOj 10.1126/science.6289436
    • GM Rubin AC Spradling 1982 Genetic transformation of Drosophila with transposable element vectors Science 218 348 353 6289436 1:CAS:528:DyaL3sXhtFOj 10.1126/science.6289436
    • (1982) Science , vol.218 , pp. 348-353
    • Rubin, G.M.1    Spradling, A.C.2
  • 110
    • 69649101282 scopus 로고    scopus 로고
    • Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organization during neuronal growth
    • 19571116 1:CAS:528:DC%2BD1MXpvFGlsr0%3D 10.1242/jcs.046268
    • N Sanchez-Soriano M Travis F Dajas-Bailador C Goncalves-Pimental AJ Whitmarsh A Prokop 2009 Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organization during neuronal growth J Cell Sci 122 2534 2542 19571116 1:CAS:528:DC%2BD1MXpvFGlsr0%3D 10.1242/jcs.046268
    • (2009) J Cell Sci , vol.122 , pp. 2534-2542
    • Sanchez-Soriano, N.1    Travis, M.2    Dajas-Bailador, F.3    Goncalves-Pimental, C.4    Whitmarsh, A.J.5    Prokop, A.6
  • 111
    • 0026101131 scopus 로고
    • Clinical features of cocaine-induced paranoia
    • 2006696 1:STN:280:DyaK3M7nsVSrtA%3D%3D
    • SL Satel SM Southwick FH Gawin 1991 Clinical features of cocaine-induced paranoia Am J Psychiatry 148 495 498 2006696 1:STN:280:DyaK3M7nsVSrtA%3D%3D
    • (1991) Am J Psychiatry , vol.148 , pp. 495-498
    • Satel, S.L.1    Southwick, S.M.2    Gawin, F.H.3
  • 112
    • 0033638327 scopus 로고    scopus 로고
    • Functional ethanol tolerance in Drosophila
    • 11086999 1:CAS:528:DC%2BD3cXnvVGltLc%3D 10.1016/S0896-6273(00)00101-X
    • H Scholz J Ramond CM Singh U Heberlein 2000 Functional ethanol tolerance in Drosophila Neuron 28 261 271 11086999 1:CAS:528:DC%2BD3cXnvVGltLc%3D 10.1016/S0896-6273(00)00101-X
    • (2000) Neuron , vol.28 , pp. 261-271
    • Scholz, H.1    Ramond, J.2    Singh, C.M.3    Heberlein, U.4
  • 113
    • 23844531242 scopus 로고    scopus 로고
    • The hangover gene defines a stress pathway required for ethanol tolerance development
    • 16094367 1:CAS:528:DC%2BD2MXnt1Siu70%3D 10.1038/nature03864
    • H Scholz M Franz U Heberlein 2005 The hangover gene defines a stress pathway required for ethanol tolerance development Nature 436 845 847 16094367 1:CAS:528:DC%2BD2MXnt1Siu70%3D 10.1038/nature03864
    • (2005) Nature , vol.436 , pp. 845-847
    • Scholz, H.1    Franz, M.2    Heberlein, U.3
  • 114
    • 0028107317 scopus 로고
    • Low level of response to alcohol as a predictor of future alcoholism
    • 8296886 1:STN:280:DyaK2c7islGluw%3D%3D
    • MA Schuckit 1994 Low level of response to alcohol as a predictor of future alcoholism Am J Psychiatry 151 184 189 8296886 1:STN:280: DyaK2c7islGluw%3D%3D
    • (1994) Am J Psychiatry , vol.151 , pp. 184-189
    • Schuckit, M.A.1
  • 115
    • 0029866658 scopus 로고    scopus 로고
    • An 8-year follow-up of 450 sons of alcoholic and control subjects
    • 8611056 1:STN:280:DyaK287otlCnug%3D%3D 10.1001/archpsyc.1996. 01830030020005
    • MA Schuckit TL Smith 1996 An 8-year follow-up of 450 sons of alcoholic and control subjects Arch Gen Psychiatry 53 202 210 8611056 1:STN:280: DyaK287otlCnug%3D%3D 10.1001/archpsyc.1996.01830030020005
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 202-210
    • Schuckit, M.A.1    Smith, T.L.2
  • 117
    • 38849130750 scopus 로고    scopus 로고
    • PiggyBac-based mosaic screen identifies a postmitotic function for cohesin in regulating developmental axon pruning
    • 18267091 1:CAS:528:DC%2BD1cXit1Ojs7s%3D 10.1016/j.devcel.2007.11.001
    • O Schuldiner D Berdnik JM Levy JS Wu D Luginbuhl AC Gontang L Luo 2008 piggyBac-based mosaic screen identifies a postmitotic function for cohesin in regulating developmental axon pruning Dev Cell 14 227 238 18267091 1:CAS:528:DC%2BD1cXit1Ojs7s%3D 10.1016/j.devcel.2007.11.001
    • (2008) Dev Cell , vol.14 , pp. 227-238
    • Schuldiner, O.1    Berdnik, D.2    Levy, J.M.3    Wu, J.S.4    Luginbuhl, D.5    Gontang, A.C.6    Luo, L.7
  • 118
    • 79955569025 scopus 로고    scopus 로고
    • Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption
    • 21471458 1:CAS:528:DC%2BC3MXlslyqtrY%3D 10.1073/pnas.1017288108
    • G Schumann LJ Coin A Lourdusamy P Charoen KH Berger, et al. 2011 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption Proc Natl Acad Sci 108 7119 7124 21471458 1:CAS:528:DC%2BC3MXlslyqtrY%3D 10.1073/pnas.1017288108
    • (2011) Proc Natl Acad Sci , vol.108 , pp. 7119-7124
    • Schumann, G.1    Coin, L.J.2    Lourdusamy, A.3    Charoen, P.4    Berger, K.H.5
  • 119
    • 26244452168 scopus 로고    scopus 로고
    • GPCR signaling is required for blood-brain barrier formation in Drosophila
    • 16213218 1:CAS:528:DC%2BD2MXhtFelt7bJ 10.1016/j.cell.2005.08.037
    • T Schwabe RJ Bainton RD Fetter U Heberlein U Gaul 2005 GPCR signaling is required for blood-brain barrier formation in Drosophila Cell 123 133 134 16213218 1:CAS:528:DC%2BD2MXhtFelt7bJ 10.1016/j.cell.2005.08.037
    • (2005) Cell , vol.123 , pp. 133-134
    • Schwabe, T.1    Bainton, R.J.2    Fetter, R.D.3    Heberlein, U.4    Gaul, U.5
  • 120
    • 33644804954 scopus 로고    scopus 로고
    • Acute amphetamine down-regulates RGS4 mRNA and protein expression in rat forebrain: Distinct roles of D1 and D2 dopamine receptors
    • 16539683 1:CAS:528:DC%2BD28Xjs1OrsLk%3D 10.1111/j.1471-4159.2006.03669.x
    • M Schwendt SJ Gold JF McGinty 2006 Acute amphetamine down-regulates RGS4 mRNA and protein expression in rat forebrain: distinct roles of D1 and D2 dopamine receptors J Neurochem 96 1606 1615 16539683 1:CAS:528: DC%2BD28Xjs1OrsLk%3D 10.1111/j.1471-4159.2006.03669.x
    • (2006) J Neurochem , vol.96 , pp. 1606-1615
    • Schwendt, M.1    Gold, S.J.2    McGinty, J.F.3
  • 121
    • 34447536377 scopus 로고    scopus 로고
    • Chronic cocaine reduced RGS4 mRNA in rat prefrontal cortex and dorsal striatum
    • 17632279 1:CAS:528:DC%2BD2sXns1CmtL4%3D 10.1097/WNR.0b013e328240507a
    • M Schwendt MC Hearing RE See JF McGinty 2007 Chronic cocaine reduced RGS4 mRNA in rat prefrontal cortex and dorsal striatum NeuroReport 18 1261 1265 17632279 1:CAS:528:DC%2BD2sXns1CmtL4%3D 10.1097/WNR.0b013e328240507a
    • (2007) NeuroReport , vol.18 , pp. 1261-1265
    • Schwendt, M.1    Hearing, M.C.2    See, R.E.3    McGinty, J.F.4
  • 122
    • 47549086674 scopus 로고    scopus 로고
    • The hangover gene negatively regulates bouton addition at the Drosophila neuromuscular junction
    • 18524547 1:CAS:528:DC%2BD1cXptVKnsrw%3D 10.1016/j.mod.2008.04.004
    • I Schwenkert R Eltrop N Funk JR Steinert CM Schuster H Scholz 2008 The hangover gene negatively regulates bouton addition at the Drosophila neuromuscular junction Mech Dev 125 700 711 18524547 1:CAS:528: DC%2BD1cXptVKnsrw%3D 10.1016/j.mod.2008.04.004
    • (2008) Mech Dev , vol.125 , pp. 700-711
    • Schwenkert, I.1    Eltrop, R.2    Funk, N.3    Steinert, J.R.4    Schuster, C.M.5    Scholz, H.6
  • 123
    • 20444382383 scopus 로고    scopus 로고
    • The tipsy terminal: Presynaptic effects of ethanol
    • 15963352 1:CAS:528:DC%2BD2MXlt1Ghu74%3D 10.1016/j.pharmthera.2005.01.006
    • GR Siggins M Roberto Z Nie 2005 The tipsy terminal: presynaptic effects of ethanol Pharmacol Ther 107 80 98 15963352 1:CAS:528:DC%2BD2MXlt1Ghu74%3D 10.1016/j.pharmthera.2005.01.006
    • (2005) Pharmacol Ther , vol.107 , pp. 80-98
    • Siggins, G.R.1    Roberto, M.2    Nie, Z.3
  • 124
    • 74049110028 scopus 로고    scopus 로고
    • Mechanistic studies of ethanol's interaction with the mesolimbic dopamine reward system
    • 19434560 10.1055/s-0029-1220690 1:CAS:528:DC%2BD1MXms1Srsr4%3D
    • B Soderpalm E Lof M Ericson 2009 Mechanistic studies of ethanol's interaction with the mesolimbic dopamine reward system Pharmacopsychiatry 42 S87 S94 19434560 10.1055/s-0029-1220690 1:CAS:528:DC%2BD1MXms1Srsr4%3D
    • (2009) Pharmacopsychiatry , vol.42
    • Soderpalm, B.1    Lof, E.2    Ericson, M.3
  • 126
    • 0017652236 scopus 로고
    • The effects of 6-hydroxydopamine on tolerance and dependence on ethanol
    • 561843 1:CAS:528:DyaE1cXhtlWk
    • B Tabakoff RF Ritzmann 1977 The effects of 6-hydroxydopamine on tolerance and dependence on ethanol J Pharmacol Exp Ther 203 319 331 561843 1:CAS:528:DyaE1cXhtlWk
    • (1977) J Pharmacol Exp Ther , vol.203 , pp. 319-331
    • Tabakoff, B.1    Ritzmann, R.F.2
  • 128
    • 0032569940 scopus 로고    scopus 로고
    • Ethanol consumption and resistance are inversely related to neuropeptide y levels
    • 9845072 1:CAS:528:DyaK1cXnvVaqt7c%3D 10.1038/24614
    • TE Thiele DJ Marsh L Ste Marie IL Bernstein RD Palmiter 1998 Ethanol consumption and resistance are inversely related to neuropeptide Y levels Nature 396 366 369 9845072 1:CAS:528:DyaK1cXnvVaqt7c%3D 10.1038/24614
    • (1998) Nature , vol.396 , pp. 366-369
    • Thiele, T.E.1    Marsh, D.J.2    Ste Marie, L.3    Bernstein, I.L.4    Palmiter, R.D.5
  • 129
    • 0031923010 scopus 로고    scopus 로고
    • Activating properties of coaine and cocaethylene in a behavioral preparation of Drosophila melanogaster
    • 9593105 1:CAS:528:DyaK1cXislartb4%3D 10.1002/(SICI)1098-2396(199806)29: 2<148::AID-SYN6>3.0.CO;2-7
    • G Torres JM Horowitz 1998 Activating properties of coaine and cocaethylene in a behavioral preparation of Drosophila melanogaster Synapse 29 148 161 9593105 1:CAS:528:DyaK1cXislartb4%3D 10.1002/(SICI)1098-2396(199806)29: 2<148::AID-SYN6>3.0.CO;2-7
    • (1998) Synapse , vol.29 , pp. 148-161
    • Torres, G.1    Horowitz, J.M.2
  • 130
    • 14044254097 scopus 로고    scopus 로고
    • Lmo mutants reveal a novel role for circadian pacemaker neurons in cocaine-induced behaviors
    • 15550987 10.1371/journal.pbio.0020408 1:CAS:528:DC%2BD2cXhtFCit73F
    • LT Tsai RJ Bainton J Blau U Heberlein 2004 Lmo mutants reveal a novel role for circadian pacemaker neurons in cocaine-induced behaviors PLoS Biol 2 e408 15550987 10.1371/journal.pbio.0020408 1:CAS:528:DC%2BD2cXhtFCit73F
    • (2004) PLoS Biol , vol.2 , pp. 408
    • Tsai, L.T.1    Bainton, R.J.2    Blau, J.3    Heberlein, U.4
  • 131
    • 34247468090 scopus 로고    scopus 로고
    • Drosophila Homer is required in a small set of neurons including the ellipsoid body for normal ethanol sensitivity and tolerance
    • 17460067 1:CAS:528:DC%2BD2sXltF2jtbk%3D 10.1523/JNEUROSCI.0305-07.2007
    • NL Urizar Z Yang HJ Edenberg RL Davis 2007 Drosophila Homer is required in a small set of neurons including the ellipsoid body for normal ethanol sensitivity and tolerance J Neurosci 27 4541 4551 17460067 1:CAS:528: DC%2BD2sXltF2jtbk%3D 10.1523/JNEUROSCI.0305-07.2007
    • (2007) J Neurosci , vol.27 , pp. 4541-4551
    • Urizar, N.L.1    Yang, Z.2    Edenberg, H.J.3    Davis, R.L.4
  • 132
    • 0035879273 scopus 로고    scopus 로고
    • The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol
    • 11438605 1:CAS:528:DC%2BD3MXkvFSrsLw%3D
    • G Wand M Levine L Zweifel W Schwindinger T Abel 2001 The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol J Neurosci 21 5297 5303 11438605 1:CAS:528: DC%2BD3MXkvFSrsLw%3D
    • (2001) J Neurosci , vol.21 , pp. 5297-5303
    • Wand, G.1    Levine, M.2    Zweifel, L.3    Schwindinger, W.4    Abel, T.5
  • 133
    • 0002793095 scopus 로고
    • An apparatus for measurement of resistance to gas-phase reagents
    • KE Weber 1988 An apparatus for measurement of resistance to gas-phase reagents Drosophila Inform Serv 67 90 92
    • (1988) Drosophila Inform Serv , vol.67 , pp. 90-92
    • Weber, K.E.1
  • 134
    • 13844320378 scopus 로고    scopus 로고
    • Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity
    • 15677721 1:CAS:528:DC%2BD2MXhvFGqs7w%3D 10.1073/pnas.0406814102
    • T Wen CA Parrish D Xu Q Wu P Shen 2005 Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity Proc Natl Acad Sci USA 102 2141 2146 15677721 1:CAS:528: DC%2BD2MXhvFGqs7w%3D 10.1073/pnas.0406814102
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2141-2146
    • Wen, T.1    Parrish, C.A.2    Xu, D.3    Wu, Q.4    Shen, P.5
  • 135
    • 0028248608 scopus 로고
    • Effects of alcohol on gene expression in neural cells
    • 8032172 1:CAS:528:DyaK2cXlsFWis7w%3D
    • N Wilke M Sganga S Barhite MF Miles 1994 Effects of alcohol on gene expression in neural cells EXS 71 49 59 8032172 1:CAS:528:DyaK2cXlsFWis7w%3D
    • (1994) EXS , vol.71 , pp. 49-59
    • Wilke, N.1    Sganga, M.2    Barhite, S.3    Miles, M.F.4
  • 136
    • 0037114960 scopus 로고    scopus 로고
    • High-resolution analysis of ethanol-induced locomotor stimulation in Drosophila
    • 12486199 1:CAS:528:DC%2BD38XpslCqtbk%3D
    • FW Wolf AR Rodan LT-Y Tsai U Heberlein 2002 High-resolution analysis of ethanol-induced locomotor stimulation in Drosophila J Neurosci 22 11035 11044 12486199 1:CAS:528:DC%2BD38XpslCqtbk%3D
    • (2002) J Neurosci , vol.22 , pp. 11035-11044
    • Wolf, F.W.1    Rodan, A.R.2    Lt-Y, T.3    Heberlein, U.4
  • 137
    • 67649968443 scopus 로고    scopus 로고
    • Oxidative stress and alcoholic liver disease
    • 19387914 1:CAS:528:DC%2BD1MXmt1Gru78%3D 10.1055/s-0029-1214370
    • D Wu AI Cederbaum 2009 Oxidative stress and alcoholic liver disease Semin Liver Dis 29 141 154 19387914 1:CAS:528:DC%2BD1MXmt1Gru78%3D 10.1055/s-0029-1214370
    • (2009) Semin Liver Dis , vol.29 , pp. 141-154
    • Wu, D.1    Cederbaum, A.I.2
  • 138
    • 36448949477 scopus 로고    scopus 로고
    • Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body
    • 17982450 1:CAS:528:DC%2BD2sXhtlKltLfI 10.1038/nn2005
    • CL Wu S Xia TF Fu H Wang YH Chen D Leong AS Chiang T Tully 2007 Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body Nat Neurosci 10 1578 1586 17982450 1:CAS:528:DC%2BD2sXhtlKltLfI 10.1038/nn2005
    • (2007) Nat Neurosci , vol.10 , pp. 1578-1586
    • Wu, C.L.1    Xia, S.2    Fu, T.F.3    Wang, H.4    Chen, Y.H.5    Leong, D.6    Chiang, A.S.7    Tully, T.8
  • 139
    • 0030993370 scopus 로고    scopus 로고
    • Conserved and sexually dimorphic behavioral responses to biogenic amines in decapitated Drosophila
    • 10.1073/pnas.94.8.4131
    • C Yellman H Tao B He J Hirsh 1998 Conserved and sexually dimorphic behavioral responses to biogenic amines in decapitated Drosophila Proc Natl Acad Sci USA 94 4131 4136 10.1073/pnas.94.8.4131
    • (1998) Proc Natl Acad Sci USA , vol.94 , pp. 4131-4136
    • Yellman, C.1    Tao, H.2    He, B.3    Hirsh, J.4
  • 140
    • 0035105289 scopus 로고    scopus 로고
    • GABA(B) receptors play a role in the development of tolerance to ethanol in mice
    • 11243488 1:CAS:528:DC%2BD3MXhs12gtrY%3D 10.1007/s002130000581
    • MJ Zaleski JR Nunes Filho T Lemos GS Morato 2001 GABA(B) receptors play a role in the development of tolerance to ethanol in mice Psychopharmacology 153 415 424 11243488 1:CAS:528:DC%2BD3MXhs12gtrY%3D 10.1007/s002130000581
    • (2001) Psychopharmacology , vol.153 , pp. 415-424
    • Zaleski, M.J.1    Nunes Filho, J.R.2    Lemos, T.3    Morato, G.S.4


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