Preferential Ethanol Consumption in Drosophila Models Features of Addiction

Current Biology

Volumn 19, Issue 24, 2009, Pages 2126-2132

  Devineni, Anita V ^a   Heberlein, Ulrike ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

SYSNEURO

Indexed keywords

ALCOHOL; DROSOPHILA PROTEIN; INITIATION FACTOR 5; KRASAVIETZ PROTEIN, DROSOPHILA;

ALCOHOLISM; ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; CHEMISTRY; DISEASE MODEL; DRINKING BEHAVIOR; DROSOPHILA MELANOGASTER; FOOD PREFERENCE; GENETICS; ODOR; PATHOPHYSIOLOGY; PHYSIOLOGY; TASTE;

ALCOHOL DRINKING; ALCOHOLISM; ANALYSIS OF VARIANCE; ANIMALS; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ETHANOL; EUKARYOTIC INITIATION FACTOR-5; FOOD PREFERENCES; SMELL; TASTE;

DROSOPHILA MELANOGASTER; MAMMALIA;

EID: 72449139682     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2009.10.070     Document Type: Article

References (33)

1. Dick D.M., and Foroud T. Candidate genes for alcohol dependence: A review of genetic evidence from human studies. Alcohol. Clin. Exp. Res. 27 (2003) 868-879
2. Crabbe J.C., Phillips T.J., Harris R.A., Arends M.A., and Koob G.F. Alcohol-related genes: Contributions from studies with genetically engineered mice. Addict. Biol. 11 (2006) 195-269
3. Wolf F.W., Rodan A.R., Tsai L.T.-Y., and Heberlein U. High-resolution analysis of ethanol-induced locomotor stimulation in Drosophila. J. Neurosci. 22 (2002) 11035-11044
4. Scholz H., Ramond J., Singh C.M., and Heberlein U. Functional ethanol tolerance in Drosophila. Neuron 28 (2000) 261-271
5. Moore M.S., DeZazzo J., Luk A.Y., Tully T., Singh C.M., and Heberlein U. Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway. Cell 93 (1998) 997-1007
6. Maas Jr. J.W., Vogt S.K., Chan G.C., Pineda V.V., Storm D.R., and Muglia L.J. Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity. J. Neurosci. 25 (2005) 118-126
7. Wen T., Parrish C.A., Xu D., Wu Q., and Shen P. Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity. Proc. Natl. Acad. Sci. USA 102 (2005) 2141-2146
8. Thiele T.E., Marsh D.J., Ste Marie L., Bernstein I.L., and Palmiter R.D. Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Nature 396 (1998) 366-369
9. Corl A.B., Berger K.H., Ophir-Shohat G., Gesch J., Simms J.A., Bartlett S., and Heberlein U. Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors. Cell 137 (2009) 949-960
10. Ja W.W., Carvalho G.B., Mak E.M., de la Rosa N.N., Fang A.Y., Liong J.C., Brummel T., and Benzer S. Prandiology of Drosophila and the CAFE assay. Proc. Natl. Acad. Sci. USA 104 (2007) 8253-8256
11. Vosshall L.B., and Stocker R.F. Molecular architecture of smell and taste in Drosophila. Annu. Rev. Neurosci. 30 (2007) 505-533
12. French R.L., and Heberlein U. Glycogen synthase kinase-3/Shaggy mediates ethanol-induced excitotoxic cell death of Drosophila olfactory neurons. Proc. Natl. Acad. Sci. USA (2009) 10.1073/pnas.0910813106 in press. Published online November 18, 2009
13. Woodard C., Huang T., Sun H., Helfand S.L., and Carlson J. Genetic analysis of olfactory behavior in Drosophila: A new screen yields the ota mutants. Genetics 123 (1989) 315-326
14. Rothenfluh A., Threlkeld R.J., Bainton R.J., Tsai L.T.-Y., Lasek A.W., and Heberlein U. Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms. Cell 127 (2006) 199-211
15. Kiefer S.W., and Dopp J.M. Taste reactivity to alcohol in rats. Behav. Neurosci. 103 (1989) 1318-1326
16. Scinska A., Koros E., Habrat B., Kukwa A., Kostowski W., and Bienkowski P. Bitter and sweet components of ethanol taste in humans. Drug Alcohol Depend. 60 (2000) 199-206
17. Dethier V.G. The Hungry Fly (1976), Harvard University Press, Cambridge
18. Wang Z., Singhvi A., Kong P., and Scott K. Taste representations in the Drosophila brain. Cell 117 (2004) 981-991
19. Awasaki T., and Kimura K.-i. pox-neuro is required for development of chemosensory bristles in Drosophila. J. Neurobiol. 32 (1997) 707-721
20. Morse R.M., and Flavin D.K. The definition of alcoholism. JAMA 268 (1992) 1012-1014
21. Wolffgramm J., and Heyne A. Social behavior, dominance, and social deprivation of rats determine drug choice. Pharmacol. Biochem. Behav. 38 (1991) 389-399
22. Rodd Z.A., Bell R.L., Sable H.J., Murphy J.M., and McBride W.J. Recent advances in animal models of alcohol craving and relapse. Pharmacol. Biochem. Behav. 79 (2004) 439-450
23. Berger K.H., Kong E.C., Dubnau J., Tully T., Moore M.S., and Heberlein U. Ethanol sensitivity and tolerance in long-term memory mutants of Drosophila melanogaster. Alcohol. Clin. Exp. Res. 32 (2008) 895-908
24. Berger K.H., Heberlein U., and Moore M.S. Rapid and chronic: Two distinct forms of ethanol tolerance in Drosophila. Alcohol. Clin. Exp. Res. 28 (2004) 1469-1480
25. Dubnau J., Chiang A.-S., Grady L., Barditch J., Gossweiler S., McNeil J., Certa U., Broger C., and Tully T. The staufen/pumilio pathway is involved in Drosophila long-term memory. Curr. Biol. 13 (2003) 286-296
26. Belknap J.K., Crabbe J.C., and Young E.R. Voluntary consumption of ethanol in 15 inbred mouse strains. Psychopharmacology (Berl.) 112 (1993) 503-510
27. Veale W.L., and Myers R.D. Increased alcohol preference in rats following repeated exposures to alcohol. Psychopharmacologia 15 (1969) 361-372
28. Rhodes J.S., Best K., Belknap J.K., Finn D.A., and Crabbe J.C. Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice. Physiol. Behav. 84 (2005) 53-63
29. Lobina C., Agabio R., Diaz G., Fa M., Fadda F., Gessa G.L., Reali R., and Colombo G. Constant absolute ethanol intake by Sardinian alcohol-preferring rats independent of ethanol concentrations. Alcohol Alcohol. 32 (1997) 19-22
30. Joseph R.M., Devineni A.V., King I.F., and Heberlein U. Oviposition preference for and positional avoidance of acetic acid provide a model for competing behavioral drives in Drosophila. Proc. Natl. Acad. Sci. USA 106 (2009) 11352-11357
31. Suh G.S., Wong A.M., Hergarden A.C., Wang J.W., Simon A.F., Benzer S., Axel R., and Anderson D.J. A single population of olfactory sensory neurons mediates an innate avoidance behaviour in Drosophila. Nature 431 (2004) 854-859
32. Fischler W., Kong P., Marella S., and Scott K. The detection of carbonation by the Drosophila gustatory system. Nature 448 (2007) 1054-1057
33. Hyman S.E., Malenka R.C., and Nestler E.J. Neural mechanisms of addiction: The role of reward-related learning and memory. Annu. Rev. Neurosci. 29 (2006) 565-598