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Volumn 30, Issue 4, 2012, Pages 302-308

Aneuploidy and copy number variation in early human development

Author keywords

Aneuploidy; chromosomal instability; embryo

Indexed keywords

COHESIN; PROTEIN MAD2; TANKYRASE;

EID: 84862539314     PISSN: 15268004     EISSN: 15264564     Source Type: Journal    
DOI: 10.1055/s-0032-1313909     Document Type: Review
Times cited : (10)

References (64)
  • 3
    • 0035935212 scopus 로고    scopus 로고
    • The in vivo and in vitro efficiency and efficacy of PGD for aneuploidy
    • 01
    • Gianaroli L, Magli MC, Ferraretti AP. The in vivo and in vitro efficiency and efficacy of PGD for aneuploidy. Mol Cell Endocrinol: 2001; 183 01 S13 S18
    • (2001) Mol Cell Endocrinol , vol.183
    • Gianaroli, L.1    Magli, M.C.2    Ferraretti, A.P.3
  • 4
    • 26244455545 scopus 로고    scopus 로고
    • Mechanisms of aneuploidy induction in human oogenesis and early embryogenesis
    • DOI 10.1159/000086894
    • Delhanty JD. Mechanisms of aneuploidy induction in human oogenesis and early embryogenesis. Cytogenet Genome Res: 2005; 111 3-4 237 244 (Pubitemid 41414473)
    • (2005) Cytogenetic and Genome Research , vol.111 , Issue.3-4 , pp. 237-244
    • Delhanty, J.D.A.1
  • 6
    • 4243089454 scopus 로고    scopus 로고
    • Increased rate of aneuploid embryos in young women with previous aneuploid conceptions
    • DOI 10.1002/pd.957
    • Munné S, Sandalinas M, Magli C, Gianaroli L, Cohen J, Warburton D. Increased rate of aneuploid embryos in young women with previous aneuploid conceptions. Prenat Diagn: 2004; 24 8 638 643 (Pubitemid 39108572)
    • (2004) Prenatal Diagnosis , vol.24 , Issue.8 , pp. 638-643
    • Munne, S.1    Sandalinas, M.2    Magli, C.3    Gianaroli, L.4    Cohen, J.5    Warburton, D.6
  • 8
    • 0034064674 scopus 로고    scopus 로고
    • Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization
    • DOI 10.1007/s004390051030
    • Voullaire L, Slater H, Williamson R, Wilton L. Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization. Hum Genet: 2000; 106 2 210 217 (Pubitemid 30156426)
    • (2000) Human Genetics , vol.106 , Issue.2 , pp. 210-217
    • Voullaire, L.1    Slater, H.2    Williamson, R.3    Wilton, L.4
  • 9
    • 78650416518 scopus 로고    scopus 로고
    • Comprehensive embryo analysis of advanced maternal age-related aneuploidies and mosaicism by short comparative genomic hybridization
    • Rius M, Daina G, Obradors A., et al. Comprehensive embryo analysis of advanced maternal age-related aneuploidies and mosaicism by short comparative genomic hybridization. Fertil Steril: 2011; 95 1 413 416
    • (2011) Fertil Steril , vol.95 , Issue.1 , pp. 413-416
    • Rius, M.1    Daina, G.2    Obradors, A.3
  • 10
    • 0033679573 scopus 로고    scopus 로고
    • Comprehensive chromosomal analysis of human preimplantation embryos using whole genome amplification and single cell comparative genomic hybridization
    • Wells D, Delhanty JD. Comprehensive chromosomal analysis of human preimplantation embryos using whole genome amplification and single cell comparative genomic hybridization. Mol Hum Reprod: 2000; 6 11 1055 1062
    • (2000) Mol Hum Reprod , vol.6 , Issue.11 , pp. 1055-1062
    • Wells, D.1    Delhanty, J.D.2
  • 11
    • 0036849745 scopus 로고    scopus 로고
    • Chromosome abnormalities identified by comparative genomic hybridization in embryos from women with repeated implantation failure
    • Voullaire L, Wilton L, McBain J, Callaghan T, Williamson R. Chromosome abnormalities identified by comparative genomic hybridization in embryos from women with repeated implantation failure. Mol Hum Reprod: 2002; 8 11 1035 1041 (Pubitemid 35331809)
    • (2002) Molecular Human Reproduction , vol.8 , Issue.11 , pp. 1035-1041
    • Voullaire, L.1    Wilton, L.2    McBain, J.3    Callaghan, T.4    Williamson, R.5
  • 12
    • 0038311951 scopus 로고    scopus 로고
    • Preimplantation aneuploidy screening using comparative genomic hybridization or fluorescence in situ hybridization of embryos from patients with recurrent implantation failure
    • DOI 10.1016/S0015-0282(03)01162-2
    • Wilton L, Voullaire L, Sargeant P, Williamson R, McBain J. Preimplantation aneuploidy screening using comparative genomic hybridization or fluorescence in situ hybridization of embryos from patients with recurrent implantation failure. Fertil Steril: 2003; 80 4 860 868 (Pubitemid 37230016)
    • (2003) Fertility and Sterility , vol.80 , Issue.4 , pp. 860-868
    • Wilton, L.1    Voullaire, L.2    Sargeant, P.3    Williamson, R.4    McBain, J.5
  • 14
    • 0032836396 scopus 로고    scopus 로고
    • Detection of aneuploidy in single cells using comparative genomic hybridization
    • DOI 10.1002/(SICI)1097-0223(199909)19:9<846::AID-PD657>3.0.CO;2-#
    • Voullaire L, Wilton L, Slater H, Williamson R. Detection of aneuploidy in single cells using comparative genomic hybridization. Prenat Diagn: 1999; 19 9 846 851 (Pubitemid 29438175)
    • (1999) Prenatal Diagnosis , vol.19 , Issue.9 , pp. 846-851
    • Voullaire, L.1    Wilton, L.2    Slater, H.3    Williamson, R.4
  • 15
    • 66749169417 scopus 로고    scopus 로고
    • Chromosome instability is common in human cleavage-stage embryos
    • Vanneste E, Voet T, Le Caignec C., et al. Chromosome instability is common in human cleavage-stage embryos. Nat Med: 2009; 15 5 577 583
    • (2009) Nat Med , vol.15 , Issue.5 , pp. 577-583
    • Vanneste, E.1    Voet, T.2    Le Caignec, C.3
  • 16
    • 69849093233 scopus 로고    scopus 로고
    • Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays
    • Geigl JB, Obenauf AC, Waldispuehl-Geigl J., et al. Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays. Nucleic Acids Res: 2009; 37 15 e105
    • (2009) Nucleic Acids Res , vol.37 , Issue.15
    • Geigl, J.B.1    Obenauf, A.C.2    Waldispuehl-Geigl, J.3
  • 17
    • 44949125672 scopus 로고    scopus 로고
    • Detection of chromosomal structural alterations in single cells by SNP arrays: A systematic survey of amplification bias and optimized workflow
    • Iwamoto K, Bundo M, Ueda J., et al. Detection of chromosomal structural alterations in single cells by SNP arrays: a systematic survey of amplification bias and optimized workflow. PLoS ONE: 2007; 2 12 e1306
    • (2007) PLoS ONE , vol.2 , Issue.12
    • Iwamoto, K.1    Bundo, M.2    Ueda, J.3
  • 18
    • 33847347259 scopus 로고    scopus 로고
    • High resolution array-CGH analysis of single cells
    • Fiegler H, Geigl JB, Langer S., et al. High resolution array-CGH analysis of single cells. Nucleic Acids Res: 2007; 35 3 e15
    • (2007) Nucleic Acids Res , vol.35 , Issue.3
    • Fiegler, H.1    Geigl, J.B.2    Langer, S.3
  • 19
    • 77955162240 scopus 로고    scopus 로고
    • Accurate single cell 24 chromosome aneuploidy screening using whole genome amplification and single nucleotide polymorphism microarrays
    • Treff NR, Su J, Tao X, Levy B, Scott RT Jr. Accurate single cell 24 chromosome aneuploidy screening using whole genome amplification and single nucleotide polymorphism microarrays. Fertil Steril: 2010; 94 6 2017 2021
    • (2010) Fertil Steril , vol.94 , Issue.6 , pp. 2017-2021
    • Treff, N.R.1    Su, J.2    Tao, X.3    Levy, B.4    Scott Jr., R.T.5
  • 20
    • 77955123936 scopus 로고    scopus 로고
    • SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISH
    • Treff NR, Levy B, Su J, Northrop LE, Tao X, Scott RT Jr. SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISH. Mol Hum Reprod: 2010; 16 8 583 589
    • (2010) Mol Hum Reprod , vol.16 , Issue.8 , pp. 583-589
    • Treff, N.R.1    Levy, B.2    Su, J.3    Northrop, L.E.4    Tao, X.5    Scott Jr., R.T.6
  • 21
    • 58149088047 scopus 로고    scopus 로고
    • Successful pregnancies after application of array-comparative genomic hybridization in PGS-aneuploidy screening
    • Hellani A, Abu-Amero K, Azouri J, El-Akoum S. Successful pregnancies after application of array-comparative genomic hybridization in PGS-aneuploidy screening. Reprod Biomed Online: 2008; 17 6 841 847
    • (2008) Reprod Biomed Online , vol.17 , Issue.6 , pp. 841-847
    • Hellani, A.1    Abu-Amero, K.2    Azouri, J.3    El-Akoum, S.4
  • 22
    • 77949964519 scopus 로고    scopus 로고
    • Preclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocol
    • Johnson DS, Gemelos G, Baner J., et al. Preclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocol. Hum Reprod: 2010; 25 4 1066 1075
    • (2010) Hum Reprod , vol.25 , Issue.4 , pp. 1066-1075
    • Johnson, D.S.1    Gemelos, G.2    Baner, J.3
  • 23
    • 58249096083 scopus 로고    scopus 로고
    • Use of comprehensive chromosomal screening for embryo assessment: Microarrays and CGH
    • Wells D, Alfarawati S, Fragouli E. Use of comprehensive chromosomal screening for embryo assessment: microarrays and CGH. Mol Hum Reprod: 2008; 14 12 703 710
    • (2008) Mol Hum Reprod , vol.14 , Issue.12 , pp. 703-710
    • Wells, D.1    Alfarawati, S.2    Fragouli, E.3
  • 24
    • 79957478276 scopus 로고    scopus 로고
    • First births after preimplantation genetic diagnosis of structural chromosome abnormalities using comparative genomic hybridization and microarray analysis
    • Alfarawati S, Fragouli E, Colls P, Wells D. First births after preimplantation genetic diagnosis of structural chromosome abnormalities using comparative genomic hybridization and microarray analysis. Hum Reprod: 2011; 26 6 1560 1574
    • (2011) Hum Reprod , vol.26 , Issue.6 , pp. 1560-1574
    • Alfarawati, S.1    Fragouli, E.2    Colls, P.3    Wells, D.4
  • 25
    • 75749105774 scopus 로고    scopus 로고
    • Live birth after polar body array comparative genomic hybridization prediction of embryo ploidythe future of IVF
    • ., e7-e1006, e10
    • Fishel S, Gordon A, Lynch C., et al. Live birth after polar body array comparative genomic hybridization prediction of embryo ploidythe future of IVF? Fertil Steril: 2010; 93 3 1006, e7-e1006, e10
    • (2010) Fertil Steril , vol.93 , Issue.3 , pp. 1006
    • Fishel, S.1    Gordon, A.2    Lynch, C.3
  • 26
    • 75149121970 scopus 로고    scopus 로고
    • The impact of ovarian stimulation for IVF on the developing embryo
    • Santos MA, Kuijk EW, Macklon NS. The impact of ovarian stimulation for IVF on the developing embryo. Reproduction: 2010; 139 1 23 34
    • (2010) Reproduction , vol.139 , Issue.1 , pp. 23-34
    • Santos, M.A.1    Kuijk, E.W.2    MacKlon, N.S.3
  • 27
    • 77955066602 scopus 로고    scopus 로고
    • Mosaic uniparental disomies and aneuploidies as large structural variants of the human genome
    • Rodríguez-Santiago B, Malats N, Rothman N., et al. Mosaic uniparental disomies and aneuploidies as large structural variants of the human genome. Am J Hum Genet: 2010; 87 1 129 138
    • (2010) Am J Hum Genet , vol.87 , Issue.1 , pp. 129-138
    • Rodríguez-Santiago, B.1    Malats, N.2    Rothman, N.3
  • 28
    • 77951702768 scopus 로고    scopus 로고
    • Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysis
    • Conlin LK, Thiel BD, Bonnemann CG., et al. Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysis. Hum Mol Genet: 2010; 19 7 1263 1275
    • (2010) Hum Mol Genet , vol.19 , Issue.7 , pp. 1263-1275
    • Conlin, L.K.1    Thiel, B.D.2    Bonnemann, C.G.3
  • 29
    • 0036629078 scopus 로고    scopus 로고
    • Conception to ongoing pregnancy: The 'black box' of early pregnancy loss
    • DOI 10.1093/humupd/8.4.333
    • Macklon NS, Geraedts JP, Fauser BC. Conception to ongoing pregnancy: the black box' of early pregnancy loss. Hum Reprod Update: 2002; 8 4 333 343 (Pubitemid 34919248)
    • (2002) Human Reproduction Update , vol.8 , Issue.4 , pp. 333-343
    • Macklon, N.S.1    Geraedts, J.P.M.2    Fauser, B.C.J.M.3
  • 30
    • 77949725632 scopus 로고    scopus 로고
    • Early embryonic chromosome instability results in stable mosaic pattern in human tissues
    • Mkrtchyan H, Gross M, Hinreiner S., et al. Early embryonic chromosome instability results in stable mosaic pattern in human tissues. PLoS ONE: 2010; 5 3 e9591
    • (2010) PLoS ONE , vol.5 , Issue.3
    • Mkrtchyan, H.1    Gross, M.2    Hinreiner, S.3
  • 31
    • 34347242092 scopus 로고    scopus 로고
    • Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: A randomized controlled trial
    • Baart EB, Martini E, Eijkemans MJ., et al. Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial. Hum Reprod: 2007; 22 4 980 988
    • (2007) Hum Reprod , vol.22 , Issue.4 , pp. 980-988
    • Baart, E.B.1    Martini, E.2    Eijkemans, M.J.3
  • 32
    • 79954607745 scopus 로고    scopus 로고
    • The human cleavage stage embryo is a cradle of chromosomal rearrangements
    • Voet T, Vanneste E, Vermeesch JR. The human cleavage stage embryo is a cradle of chromosomal rearrangements. Cytogenet Genome Res: 2011; 133 2-4 160 168
    • (2011) Cytogenet Genome Res , vol.133 , Issue.24 , pp. 160-168
    • Voet, T.1    Vanneste, E.2    Vermeesch, J.R.3
  • 33
    • 0035319804 scopus 로고    scopus 로고
    • To err (meiotically) is human: The genesis of human aneuploidy
    • DOI 10.1038/35066065
    • Hassold T, Hunt P. To err (meiotically) is human: the genesis of human aneuploidy. Nat Rev Genet: 2001; 2 4 280 291 (Pubitemid 33674776)
    • (2001) Nature Reviews Genetics , vol.2 , Issue.4 , pp. 280-291
    • Hassold, T.1    Hunt, P.2
  • 34
    • 79955781600 scopus 로고    scopus 로고
    • The cytogenetics of polar bodies: Insights into female meiosis and the diagnosis of aneuploidy
    • April 14 (Epub ahead of print)
    • Fragouli E, Alfarawati S, Goodall NN, Sanchez-Garcia JF, Colls P, Wells D. The cytogenetics of polar bodies: insights into female meiosis and the diagnosis of aneuploidy. Mol Hum Reprod: 2011;; April 14 (Epub ahead of print)
    • (2011) Mol Hum Reprod
    • Fragouli, E.1    Alfarawati, S.2    Goodall, N.N.3    Sanchez-Garcia, J.F.4    Colls, P.5    Wells, D.6
  • 35
    • 38449087657 scopus 로고    scopus 로고
    • The origin of human aneuploidy: Where we have been, where we are going
    • SPEC NO. 2
    • Hassold T, Hall H, Hunt P. The origin of human aneuploidy: where we have been, where we are going. Hum Mol Genet: 2007; 16 Spec No. 2 R203 R208
    • (2007) Hum Mol Genet , Issue.16
    • Hassold, T.1    Hall, H.2    Hunt, P.3
  • 37
    • 4243089454 scopus 로고    scopus 로고
    • Increased rate of aneuploid embryos in young women with previous aneuploid conceptions
    • DOI 10.1002/pd.957
    • Munné S, Sandalinas M, Magli C, Gianaroli L, Cohen J, Warburton D. Increased rate of aneuploid embryos in young women with previous aneuploid conceptions. Prenat Diagn: 2004; 24 8 638 643 (Pubitemid 39108572)
    • (2004) Prenatal Diagnosis , vol.24 , Issue.8 , pp. 638-643
    • Munne, S.1    Sandalinas, M.2    Magli, C.3    Gianaroli, L.4    Cohen, J.5    Warburton, D.6
  • 38
    • 79959689944 scopus 로고    scopus 로고
    • Breakage-fusion-bridge cycles leading to inv dup del occur in human cleavage stage embryos
    • Voet T, Vanneste E, Van der Aa N., et al. Breakage-fusion-bridge cycles leading to inv dup del occur in human cleavage stage embryos. Hum Mutat: 2011; 32 7 783 793
    • (2011) Hum Mutat , vol.32 , Issue.7 , pp. 783-793
    • Voet, T.1    Vanneste, E.2    Van Der Aa, N.3
  • 39
    • 13444280505 scopus 로고    scopus 로고
    • Preimplantation genetic diagnosis and chromosome analysis of blastomeres using comparative genomic hybridization
    • DOI 10.1093/humupd/dmh050
    • Wilton L. Preimplantation genetic diagnosis and chromosome analysis of blastomeres using comparative genomic hybridization. Hum Reprod Update: 2005; 11 1 33 41 (Pubitemid 40201974)
    • (2005) Human Reproduction Update , vol.11 , Issue.1 , pp. 33-41
    • Wilton, L.1
  • 43
    • 0029295123 scopus 로고
    • The origin of genetic defects in the human and their detection in the preimplantation embryo
    • Delhanty JD, Handyside AH. The origin of genetic defects in the human and their detection in the preimplantation embryo. Hum Reprod Update: 1995; 1 3 201 215
    • (1995) Hum Reprod Update , vol.1 , Issue.3 , pp. 201-215
    • Delhanty, J.D.1    Handyside, A.H.2
  • 44
    • 67649522162 scopus 로고    scopus 로고
    • Boveri revisited: Chromosomal instability, aneuploidy and tumorigenesis
    • Holland AJ, Cleveland DW. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol: 2009; 10 7 478 487
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.7 , pp. 478-487
    • Holland, A.J.1    Cleveland, D.W.2
  • 45
    • 0036905378 scopus 로고    scopus 로고
    • High rate of mixoploidy among human blastocysts cultured in vitro
    • DOI 10.1016/S0015-0282(02)04393-5, PII S0015028202043935
    • Bielanska M, Tan SL, Ao A. High rate of mixoploidy among human blastocysts cultured in vitro. Fertil Steril: 2002; 78 6 1248 1253 (Pubitemid 35463122)
    • (2002) Fertility and Sterility , vol.78 , Issue.6 , pp. 1248-1253
    • Bielanska, M.1    Tan, S.L.2    Ao, A.3
  • 47
    • 0028931223 scopus 로고
    • Assessment of numeric abnormalities of X, Y, 18, and 16 chromosomes in preimplantation human embryos before transfer
    • discussion 1199-1201
    • Munné S, Sultan KM, Weier HU, Grifo JA, Cohen J, Rosenwaks Z. Assessment of numeric abnormalities of X, Y, 18, and 16 chromosomes in preimplantation human embryos before transfer. Am J Obstet Gynecol: 1995; 172 4 Pt 1 1191 1199, discussion 1199-1201
    • (1995) Am J Obstet Gynecol , vol.172 , Issue.4 PART 1 , pp. 1191-1199
    • Munné, S.1    Sultan, K.M.2    Weier, H.U.3    Grifo, J.A.4    Cohen, J.5    Rosenwaks, Z.6
  • 48
    • 15844399776 scopus 로고    scopus 로고
    • Spindle abnormalities in normally developing and arrested human preimplantation embryos in vitro identified by confocal laser scanning microscopy
    • DOI 10.1093/humrep/deh652
    • Chatzimeletiou K, Morrison EE, Prapas N, Prapas Y, Handyside AH. Spindle abnormalities in normally developing and arrested human preimplantation embryos in vitro identified by confocal laser scanning microscopy. Hum Reprod: 2005; 20 3 672 682 (Pubitemid 40425493)
    • (2005) Human Reproduction , vol.20 , Issue.3 , pp. 672-682
    • Chatzimeletiou, K.1    Morrison, E.E.2    Prapas, N.3    Prapas, Y.4    Handyside, A.H.5
  • 49
    • 79959833877 scopus 로고    scopus 로고
    • Telomere DNA deficiency is associated with development of human embryonic aneuploidy
    • Treff NR, Su J, Taylor D, Scott RT Jr. Telomere DNA deficiency is associated with development of human embryonic aneuploidy. PLoS Genet: 2011; 7 6 e1002161
    • (2011) PLoS Genet , vol.7 , Issue.6
    • Treff, N.R.1    Su, J.2    Taylor, D.3    Scott Jr., R.T.4
  • 50
    • 0034890364 scopus 로고    scopus 로고
    • Complex and segmental uniparental disomy (UPD): Review and lessons from rare chromosomal complements
    • Kotzot D. Complex and segmental uniparental disomy (UPD): review and lessons from rare chromosomal complements. J Med Genet: 2001; 38 8 497 507 (Pubitemid 32751577)
    • (2001) Journal of Medical Genetics , vol.38 , Issue.8 , pp. 497-507
    • Kotzot, D.1
  • 51
    • 51849158675 scopus 로고    scopus 로고
    • Complex and segmental uniparental disomy updated
    • Kotzot D. Complex and segmental uniparental disomy updated. J Med Genet: 2008; 45 9 545 556
    • (2008) J Med Genet , vol.45 , Issue.9 , pp. 545-556
    • Kotzot, D.1
  • 52
    • 34548085071 scopus 로고    scopus 로고
    • Motile human normozoospermic and oligozoospermic semen samples show a difference in double-strand DNA break incidence
    • DOI 10.1093/humrep/dem166
    • Derijck AA, Van Der Heijden GW, Ramos L, Giele M, Kremer JA, De Boer P. Motile human normozoospermic and oligozoospermic semen samples show a difference in double-strand DNA break incidence. Hum Reprod: 2007; 22 9 2368 2376 (Pubitemid 47289051)
    • (2007) Human Reproduction , vol.22 , Issue.9 , pp. 2368-2376
    • Derijck, A.A.H.A.1    Van Der Heijden, G.W.2    Ramos, L.3    Giele, M.4    Kremer, J.A.M.5    De Boer, P.6
  • 53
    • 58149289746 scopus 로고    scopus 로고
    • Biological and clinical significance of DNA damage in the male germ line
    • Aitken RJ, De Iuliis GN, McLachlan RI. Biological and clinical significance of DNA damage in the male germ line. Int J Androl: 2009; 32 1 46 56
    • (2009) Int J Androl , vol.32 , Issue.1 , pp. 46-56
    • Aitken, R.J.1    De Iuliis, G.N.2    McLachlan, R.I.3
  • 54
    • 39449096135 scopus 로고    scopus 로고
    • Genome instability: A mechanistic view of its causes and consequences
    • DOI 10.1038/nrg2268, PII NRG2268
    • Aguilera A, Gómez-González B. Genome instability: a mechanistic view of its causes and consequences. Nat Rev Genet: 2008; 9 3 204 217 (Pubitemid 351271797)
    • (2008) Nature Reviews Genetics , vol.9 , Issue.3 , pp. 204-217
    • Aguilera, A.1    Gomez-Gonzalez, B.2
  • 55
    • 61449168034 scopus 로고    scopus 로고
    • Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ
    • Hsiao SJ, Smith S. Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ. J Cell Biol: 2009; 184 4 515 526
    • (2009) J Cell Biol , vol.184 , Issue.4 , pp. 515-526
    • Hsiao, S.J.1    Smith, S.2
  • 56
    • 64649090292 scopus 로고    scopus 로고
    • Targeting DNA topoisomerase II in cancer chemotherapy
    • Nitiss JL. Targeting DNA topoisomerase II in cancer chemotherapy. Nat Rev Cancer: 2009; 9 5 338 350
    • (2009) Nat Rev Cancer , vol.9 , Issue.5 , pp. 338-350
    • Nitiss, J.L.1
  • 57
    • 14044258836 scopus 로고    scopus 로고
    • Centric fissionsimple and complex mechanisms
    • Perry J, Slater HR, Choo KH. Centric fissionsimple and complex mechanisms. Chromosome Res: 2004; 12 6 627 640
    • (2004) Chromosome Res , vol.12 , Issue.6 , pp. 627-640
    • Perry, J.1    Slater, H.R.2    Choo, K.H.3
  • 58
    • 77749252004 scopus 로고    scopus 로고
    • Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle
    • Guerrero AA, Gamero MC, Trachana V., et al. Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle. Proc Natl Acad Sci U S A: 2010; 107 9 4159 4164
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.9 , pp. 4159-4164
    • Guerrero, A.A.1    Gamero, M.C.2    Trachana, V.3
  • 59
    • 77953946465 scopus 로고    scopus 로고
    • Merotelic attachments and non-homologous end joining are the basis of chromosomal instability
    • Guerrero AA, Martínez-A C, van Wely KH. Merotelic attachments and non-homologous end joining are the basis of chromosomal instability. Cell Div: 2010; 5 13
    • (2010) Cell Div , vol.5 , pp. 13
    • Guerrero, A.A.1    Martínez-A, C.2    Van Wely, K.H.3
  • 60
    • 77953951382 scopus 로고    scopus 로고
    • Are aneuploidy and chromosome breakage caused by a CINgle mechanism
    • Martínez-A C, van Wely KH. Are aneuploidy and chromosome breakage caused by a CINgle mechanism? Cell Cycle: 2010; 9 12 2275 2280
    • (2010) Cell Cycle , vol.9 , Issue.12 , pp. 2275-2280
    • Martínez-A, C.1    Van Wely, K.H.2
  • 62
    • 40749092486 scopus 로고    scopus 로고
    • Neocentromeres: New Insights into Centromere Structure, Disease Development, and Karyotype Evolution
    • DOI 10.1016/j.ajhg.2007.11.009, PII S0002929708000931
    • Marshall OJ, Chueh AC, Wong LH, Choo KH. Neocentromeres: new insights into centromere structure, disease development, and karyotype evolution. Am J Hum Genet: 2008; 82 2 261 282 (Pubitemid 351726108)
    • (2008) American Journal of Human Genetics , vol.82 , Issue.2 , pp. 261-282
    • Marshall, O.J.1    Chueh, A.C.2    Wong, L.H.3    Choo, K.H.A.4
  • 63
    • 66549096195 scopus 로고    scopus 로고
    • Inverted duplications deletions: Underdiagnosed rearrangements
    • Zuffardi O, Bonaglia M, Ciccone R, Giorda R. Inverted duplications deletions: underdiagnosed rearrangements Clin Genet: 2009; 75 6 505 513
    • (2009) Clin Genet , vol.75 , Issue.6 , pp. 505-513
    • Zuffardi, O.1    Bonaglia, M.2    Ciccone, R.3    Giorda, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.