메뉴 건너뛰기




Volumn 22, Issue 9, 2007, Pages 2368-2376

Motile human normozoospermic and oligozoospermic semen samples show a difference in double-strand DNA break incidence

Author keywords

Chromatin; DNA degradation; Double strand DNA break; ICSI; Sperm

Indexed keywords

CELL NUCLEUS DNA; DOUBLE STRANDED DNA;

EID: 34548085071     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dem166     Document Type: Article
Times cited : (30)

References (58)
  • 1
    • 0031563793 scopus 로고    scopus 로고
    • Susceptibility of human sperm to in situ DNA denaturation is strongly correlated with DNA strand breaks identified by single-cell electrophoresis
    • Aravindan GR, Bjordahl J, Jost LK, Evenson DP. Susceptibility of human sperm to in situ DNA denaturation is strongly correlated with DNA strand breaks identified by single-cell electrophoresis. Exp Cell Res 1997; 236:231-237.
    • (1997) Exp Cell Res , vol.236 , pp. 231-237
    • Aravindan, G.R.1    Bjordahl, J.2    Jost, L.K.3    Evenson, D.P.4
  • 2
    • 2442566822 scopus 로고    scopus 로고
    • Reduced oocyte activation and first cleavage rate after ICSI with spermatozoa from a sterile mouse chromosome mutant
    • Baart EB, van der Heijden GW, van der Hoeven FA, Bakker R, Cooper TG, de Boer P. Reduced oocyte activation and first cleavage rate after ICSI with spermatozoa from a sterile mouse chromosome mutant. Hum Reprod 2004;19:1140-1147.
    • (2004) Hum Reprod , vol.19 , pp. 1140-1147
    • Baart, E.B.1    van der Heijden, G.W.2    van der Hoeven, F.A.3    Bakker, R.4    Cooper, T.G.5    de Boer, P.6
  • 3
    • 0029870112 scopus 로고    scopus 로고
    • DNA and total protamine masses in individual sperm from fertile mammalian subjects
    • Bench GS, Friz AM, Corzett MH, Morse DH, Balhorn R. DNA and total protamine masses in individual sperm from fertile mammalian subjects. Cytometry 1996;23:263-271.
    • (1996) Cytometry , vol.23 , pp. 263-271
    • Bench, G.S.1    Friz, A.M.2    Corzett, M.H.3    Morse, D.H.4    Balhorn, R.5
  • 4
    • 0034251662 scopus 로고    scopus 로고
    • Sperm decondensation during fertilisation in the mouse: Presence of DNase I hypersensitive sites in situ and a putative role for topoisomerase II
    • Bizzaro D, Manicardi G, Bianchi PG, Sakkas D. Sperm decondensation during fertilisation in the mouse: Presence of DNase I hypersensitive sites in situ and a putative role for topoisomerase II. Zygote 2000;8:197-202.
    • (2000) Zygote , vol.8 , pp. 197-202
    • Bizzaro, D.1    Manicardi, G.2    Bianchi, P.G.3    Sakkas, D.4
  • 5
    • 0036798423 scopus 로고    scopus 로고
    • Prenatal testing in ICSI pregnancies: Incidence of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters
    • Bonduelle M, Van AE, Joris H, Keymolen K, Devroey P, Van Steirteghem A, Liebaers I. Prenatal testing in ICSI pregnancies: Incidence of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters. Hum Reprod 2002;17:2600-2614.
    • (2002) Hum Reprod , vol.17 , pp. 2600-2614
    • Bonduelle, M.1    Van, A.E.2    Joris, H.3    Keymolen, K.4    Devroey, P.5    Van Steirteghem, A.6    Liebaers, I.7
  • 7
    • 0016218441 scopus 로고
    • Spermatozoa: The probable selection of a small population by the genital tract of the female rabbit
    • Cohen J, McNaughton DC. Spermatozoa: The probable selection of a small population by the genital tract of the female rabbit. J Reprod Fertil 1974;39:297-310.
    • (1974) J Reprod Fertil , vol.39 , pp. 297-310
    • Cohen, J.1    McNaughton, D.C.2
  • 8
    • 0022650326 scopus 로고
    • Male pachytene pairing in single and double translocation heterozygotes and spermatogenic impairment in the mouse
    • de Boer P, Searle AG, van der Hoeven FA, de Rooij DG, Beechey CV. Male pachytene pairing in single and double translocation heterozygotes and spermatogenic impairment in the mouse. Chromosoma 1986;93 326-336.
    • (1986) Chromosoma , vol.93 , pp. 326-336
    • de Boer, P.1    Searle, A.G.2    van der Hoeven, F.A.3    de Rooij, D.G.4    Beechey, C.V.5
  • 9
    • 33746352397 scopus 로고    scopus 로고
    • Derijck AA, van der Heijden GW, Giele M, Philippens ME, van Bavel CC, de BP. gammaH2AX signalling during sperm chromatin remodelling in the mouse zygote. DNA Repair (Amst) 2006;5:959-971.
    • Derijck AA, van der Heijden GW, Giele M, Philippens ME, van Bavel CC, de BP. gammaH2AX signalling during sperm chromatin remodelling in the mouse zygote. DNA Repair (Amst) 2006;5:959-971.
  • 10
    • 0034762121 scopus 로고    scopus 로고
    • Cryopreservation of human semen and prepared sperm: Effects on motility parameters and DNA integrity
    • Donnelly ET, McClure N, Lewis SEM. Cryopreservation of human semen and prepared sperm: Effects on motility parameters and DNA integrity. Fertil Steril 2001;76:892-900.
    • (2001) Fertil Steril , vol.76 , pp. 892-900
    • Donnelly, E.T.1    McClure, N.2    Lewis, S.E.M.3
  • 11
    • 0036906176 scopus 로고    scopus 로고
    • Sperm DNA quality predicts intrauterine insemination outcome: A prospective cohort study
    • Duran EH, Morshedi M, Taylor S, Oehninger S. Sperm DNA quality predicts intrauterine insemination outcome: A prospective cohort study. Hum Reprod 2002;17:3122-3128.
    • (2002) Hum Reprod , vol.17 , pp. 3122-3128
    • Duran, E.H.1    Morshedi, M.2    Taylor, S.3    Oehninger, S.4
  • 12
  • 13
    • 32844468458 scopus 로고    scopus 로고
    • Clinical aspects of sperm DNA fragmentation detection and male infertility
    • Evenson DP, Wixon R. Clinical aspects of sperm DNA fragmentation detection and male infertility. Theriogenology 2006;65 979-991.
    • (2006) Theriogenology , vol.65 , pp. 979-991
    • Evenson, D.P.1    Wixon, R.2
  • 16
    • 0035339193 scopus 로고    scopus 로고
    • Growing dictyate oocytes, but not early preimplantation embryos, of the mouse display high levels of DNA homologous recombination by single-strand annealing and lack DNA nonhomologous end joining
    • Fiorenza MT, Bevilacqua A, Bevilacqua S, Mangia F. Growing dictyate oocytes, but not early preimplantation embryos, of the mouse display high levels of DNA homologous recombination by single-strand annealing and lack DNA nonhomologous end joining. Dev Biol 2001;233 214-224.
    • (2001) Dev Biol , vol.233 , pp. 214-224
    • Fiorenza, M.T.1    Bevilacqua, A.2    Bevilacqua, S.3    Mangia, F.4
  • 17
    • 0036905608 scopus 로고    scopus 로고
    • Factors influencing the outcome of ICSI in patients with obstructive and non-obstructive azoospermia: A comparative study
    • Friedler S, Raziel A, Strassburger D, Schachter M, Soffer Y, Ron-El R. Factors influencing the outcome of ICSI in patients with obstructive and non-obstructive azoospermia: A comparative study. Hum Reprod 2002;17:3114-3121.
    • (2002) Hum Reprod , vol.17 , pp. 3114-3121
    • Friedler, S.1    Raziel, A.2    Strassburger, D.3    Schachter, M.4    Soffer, Y.5    Ron-El, R.6
  • 19
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers JH. Genome maintenance mechanisms for preventing cancer. Nature 2001;411:366-374.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 20
    • 0037173453 scopus 로고    scopus 로고
    • Radiation- and chemical-induced structural chromosome aberrations in human spermatozoa
    • Kamiguchi Y, Tateno H. Radiation- and chemical-induced structural chromosome aberrations in human spermatozoa. Mutat Res 2002;504 183-191.
    • (2002) Mutat Res , vol.504 , pp. 183-191
    • Kamiguchi, Y.1    Tateno, H.2
  • 21
    • 0028926862 scopus 로고
    • Intracytoplasmic sperm injection in the mouse
    • Kimura Y, Yanagimachi R. Intracytoplasmic sperm injection in the mouse. Biol Reprod 1995;52:709-720.
    • (1995) Biol Reprod , vol.52 , pp. 709-720
    • Kimura, Y.1    Yanagimachi, R.2
  • 22
    • 0015156648 scopus 로고
    • Radiation-iniatiated DNA synthesis in spermatogenic cells of the mouse
    • Kofman-Alfaro S, Chandley AC. Radiation-iniatiated DNA synthesis in spermatogenic cells of the mouse. Exp Cell Res 1971;69:33-44.
    • (1971) Exp Cell Res , vol.69 , pp. 33-44
    • Kofman-Alfaro, S.1    Chandley, A.C.2
  • 23
    • 22544437838 scopus 로고    scopus 로고
    • On the nature and origin of DNA strand breaks in elongating spermatids
    • Laberge RM, Boissonneault G. On the nature and origin of DNA strand breaks in elongating spermatids. Biol Reprod 2005;73:289-296.
    • (2005) Biol Reprod , vol.73 , pp. 289-296
    • Laberge, R.M.1    Boissonneault, G.2
  • 24
    • 0141958097 scopus 로고    scopus 로고
    • Relationship between the outcomes of assisted reproductive techniques and sperm DNA fragmentation as measured by the sperm chromatin structure assay
    • Larson-Cook KL, Brannian JD, Hansen KA, Kasperson KM, Aamold ET, Evenson DP. Relationship between the outcomes of assisted reproductive techniques and sperm DNA fragmentation as measured by the sperm chromatin structure assay. Fertil Steril 2003;80:895-902.
    • (2003) Fertil Steril , vol.80 , pp. 895-902
    • Larson-Cook, K.L.1    Brannian, J.D.2    Hansen, K.A.3    Kasperson, K.M.4    Aamold, E.T.5    Evenson, D.P.6
  • 25
    • 0029838780 scopus 로고    scopus 로고
    • Analysis of chromosome constitution of human spermatozoa with normal and aberrant head morphologies after injection into mouse oocytes
    • Lee JD, Kamiguchi Y, Yanagimachi R. Analysis of chromosome constitution of human spermatozoa with normal and aberrant head morphologies after injection into mouse oocytes. Hum Reprod 1996;11:1942-1946.
    • (1996) Hum Reprod , vol.11 , pp. 1942-1946
    • Lee, J.D.1    Kamiguchi, Y.2    Yanagimachi, R.3
  • 26
    • 27944478245 scopus 로고    scopus 로고
    • DNA damage to spermatozoa has impacts on fertilization and pregnancy
    • Lewis SE, Aitken RJ. DNA damage to spermatozoa has impacts on fertilization and pregnancy. Cell Tissue Res 2005;322:33-41.
    • (2005) Cell Tissue Res , vol.322 , pp. 33-41
    • Lewis, S.E.1    Aitken, R.J.2
  • 28
    • 23844495086 scopus 로고    scopus 로고
    • Mechanisms and consequences of paternally-transmitted chromosomal abnormalities
    • Marchetti F, Wyrobek AJ. Mechanisms and consequences of paternally-transmitted chromosomal abnormalities. Birth Defects Res C Embryo Today 2005;75:112-129.
    • (2005) Birth Defects Res C Embryo Today , vol.75 , pp. 112-129
    • Marchetti, F.1    Wyrobek, A.J.2
  • 29
    • 0021987715 scopus 로고
    • Studies on chromosome aberrations in the eggs of mice fertilized in vitro after irradiation. I. Chromosome aberrations induced in sperm after X-irradiation
    • Matsuda Y, Yamada T, Tobari I. Studies on chromosome aberrations in the eggs of mice fertilized in vitro after irradiation. I. Chromosome aberrations induced in sperm after X-irradiation. Mutat Res 1985; 148:113-117.
    • (1985) Mutat Res , vol.148 , pp. 113-117
    • Matsuda, Y.1    Yamada, T.2    Tobari, I.3
  • 30
    • 26244439873 scopus 로고    scopus 로고
    • ATM-dependent DNA Damage-independent Mitotic Phosphorylation of H2AX in Normally Growing Mammalian Cells
    • McManus KJ, Hendzel MJ. ATM-dependent DNA Damage-independent Mitotic Phosphorylation of H2AX in Normally Growing Mammalian Cells. Mol Biol Cell 2005;16:5013-5025.
    • (2005) Mol Biol Cell , vol.16 , pp. 5013-5025
    • McManus, K.J.1    Hendzel, M.J.2
  • 31
    • 0036108498 scopus 로고    scopus 로고
    • The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development
    • Morris ID, Ilott S, Dixon L, Brison DR. The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development. Hum Reprod 2002;17:990-998.
    • (2002) Hum Reprod , vol.17 , pp. 990-998
    • Morris, I.D.1    Ilott, S.2    Dixon, L.3    Brison, D.R.4
  • 32
    • 0002087696 scopus 로고
    • Preferential paternal origin of de novo structural chromosome rearrangements
    • Alan R. Liss, Inc
    • Olson SB, Magenis RE. Preferential paternal origin of de novo structural chromosome rearrangements. In: The Cytogenetics of Mammalian Autosomal Rearrangements. Alan R. Liss, Inc., 1988, 583-599.
    • (1988) The Cytogenetics of Mammalian Autosomal Rearrangements , pp. 583-599
    • Olson, S.B.1    Magenis, R.E.2
  • 33
    • 0034892937 scopus 로고    scopus 로고
    • Low rates of DNA fragmentation in selected motile human spermatozoa assessed by the TUNEL assay
    • Ramos L, Wetzels AM. Low rates of DNA fragmentation in selected motile human spermatozoa assessed by the TUNEL assay. Hum Reprod 2001; 16:1703-1707.
    • (2001) Hum Reprod , vol.16 , pp. 1703-1707
    • Ramos, L.1    Wetzels, A.M.2
  • 34
    • 0034621854 scopus 로고    scopus 로고
    • Frequent chromosomal translocations induced by DNA double-strand breaks
    • Richardson C, Jasin M. Frequent chromosomal translocations induced by DNA double-strand breaks. Nature 2000;405:697-700.
    • (2000) Nature , vol.405 , pp. 697-700
    • Richardson, C.1    Jasin, M.2
  • 35
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou EP, Pilch DR, Orr AH, Ivanova vs, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998;273:5858-5868.
    • (1998) J Biol Chem , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    vs, I.4    Bonner, W.M.5
  • 36
    • 0018080015 scopus 로고
    • Direct analysis of the chromonsome constitution of human spermatozoa
    • Rudak E, Jacobs PA, Yanagimachi R. Direct analysis of the chromonsome constitution of human spermatozoa. Nature 1978;274:911-913.
    • (1978) Nature , vol.274 , pp. 911-913
    • Rudak, E.1    Jacobs, P.A.2    Yanagimachi, R.3
  • 37
    • 0030929102 scopus 로고    scopus 로고
    • Disintegration of chromosomes in dead sperm cells as revealed by injection into mouse oocytes
    • Rybouchkin A, Benijts J, De SP, Dhont M. Disintegration of chromosomes in dead sperm cells as revealed by injection into mouse oocytes. Hum Reprod 1997;12:1693-1698.
    • (1997) Hum Reprod , vol.12 , pp. 1693-1698
    • Rybouchkin, A.1    Benijts, J.2    De, S.P.3    Dhont, M.4
  • 38
    • 0017836734 scopus 로고
    • A study of unscheduled DNA synthesis induced by X-rays in the germ cells of male mice
    • Sega GA, Sotomayor RE, Owens JG. A study of unscheduled DNA synthesis induced by X-rays in the germ cells of male mice. Mutat Res 1978;49:239-257.
    • (1978) Mutat Res , vol.49 , pp. 239-257
    • Sega, G.A.1    Sotomayor, R.E.2    Owens, J.G.3
  • 39
    • 4143065747 scopus 로고    scopus 로고
    • Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization
    • Seli E, Gardner DY, Schoolcraft WB, Moffatt O, Sakkas D. Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization. Fertil Steril 2004;82 378-383.
    • (2004) Fertil Steril , vol.82 , pp. 378-383
    • Seli, E.1    Gardner, D.Y.2    Schoolcraft, W.B.3    Moffatt, O.4    Sakkas, D.5
  • 40
    • 0031805709 scopus 로고    scopus 로고
    • Blastocyst development from supernumerary embryos after intracytoplasmic sperm injection: A paternal influence?
    • Shoukir Y, Chardonnens D, Campana A, Sakkas D. Blastocyst development from supernumerary embryos after intracytoplasmic sperm injection: A paternal influence? Hum Reprod 1998;13:1632-1637.
    • (1998) Hum Reprod , vol.13 , pp. 1632-1637
    • Shoukir, Y.1    Chardonnens, D.2    Campana, A.3    Sakkas, D.4
  • 41
    • 14344256084 scopus 로고    scopus 로고
    • An endogenous nuclease in hamster, mouse, and human spermatozoa cleaves DNA into loop-sized fragments
    • Sotolongo B, Huang TT, Isenberger E, Ward WS. An endogenous nuclease in hamster, mouse, and human spermatozoa cleaves DNA into loop-sized fragments. J Androl 2005;26:272-280.
    • (2005) J Androl , vol.26 , pp. 272-280
    • Sotolongo, B.1    Huang, T.T.2    Isenberger, E.3    Ward, W.S.4
  • 44
    • 27944485758 scopus 로고    scopus 로고
    • Suganuma R, Yanagimachi R, Meistrich ML. Decline in fertility of mouse sperm with abnormal chromatin during epididymal passage as revealed by ICSI. Hum Reprod 2005;20:3101-3108.
    • Suganuma R, Yanagimachi R, Meistrich ML. Decline in fertility of mouse sperm with abnormal chromatin during epididymal passage as revealed by ICSI. Hum Reprod 2005;20:3101-3108.
  • 45
    • 0031045420 scopus 로고    scopus 로고
    • Detection of deoxyribonucleic acid fragmentation in human sperm: Correlation with fertilization in vitro
    • Sun JG, Jurisicova A, Casper RF. Detection of deoxyribonucleic acid fragmentation in human sperm: Correlation with fertilization in vitro. Blol Reprod 1997;56:602-607.
    • (1997) Blol Reprod , vol.56 , pp. 602-607
    • Sun, J.G.1    Jurisicova, A.2    Casper, R.F.3
  • 46
    • 1542711820 scopus 로고    scopus 로고
    • Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation
    • Tesarik J, Greco E, Mendoza C. Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation. Hum Reprod 2004;19:611-615.
    • (2004) Hum Reprod , vol.19 , pp. 611-615
    • Tesarik, J.1    Greco, E.2    Mendoza, C.3
  • 47
    • 0036161374 scopus 로고    scopus 로고
    • Paternal effect acting during the first cell cycle of human preimplantation development after ICST
    • Tesarik J, Mendoza C, Greeo E. Paternal effect acting during the first cell cycle of human preimplantation development after ICST. Hum Reprod 2002;17:184-189.
    • (2002) Hum Reprod , vol.17 , pp. 184-189
    • Tesarik, J.1    Mendoza, C.2    Greeo, E.3
  • 48
    • 0034788876 scopus 로고    scopus 로고
    • Interrelationships between seminal parameters and sperm nuclear DNA damage before and after density gradient centrifugation: Implications for assisted conception
    • Tomlinson MJ, Moffatt O, Manicardi GC, Bizzaro D, Afnan M, Sakkas D. Interrelationships between seminal parameters and sperm nuclear DNA damage before and after density gradient centrifugation: Implications for assisted conception. Hum Reprod 2001;16:2160-2165.
    • (2001) Hum Reprod , vol.16 , pp. 2160-2165
    • Tomlinson, M.J.1    Moffatt, O.2    Manicardi, G.C.3    Bizzaro, D.4    Afnan, M.5    Sakkas, D.6
  • 49
    • 0032903622 scopus 로고    scopus 로고
    • No differences in outcome after intracytoplasmic sperm injection with fresh or with frozen-thawed epididymal spermatozoa
    • Tournaye H, Merdad T, Silber S, Joris H, Verheyen G, Devroey P, Van SA. No differences in outcome after intracytoplasmic sperm injection with fresh or with frozen-thawed epididymal spermatozoa. Hum Reprod 1999;14:90-95.
    • (1999) Hum Reprod , vol.14 , pp. 90-95
    • Tournaye, H.1    Merdad, T.2    Silber, S.3    Joris, H.4    Verheyen, G.5    Devroey, P.6    Van, S.A.7
  • 50
    • 33748986324 scopus 로고    scopus 로고
    • Transmission of modified nucleosomes from the mouse male germline to the zygote and subsequent remodeling of paternal chromatin
    • van der Heijden GW, Derijck AA, Ramos L, Giele M, van der Vlag J, de Boer P. Transmission of modified nucleosomes from the mouse male germline to the zygote and subsequent remodeling of paternal chromatin. Dev Biol 2006;298:458-469.
    • (2006) Dev Biol , vol.298 , pp. 458-469
    • van der Heijden, G.W.1    Derijck, A.A.2    Ramos, L.3    Giele, M.4    van der Vlag, J.5    de Boer, P.6
  • 52
    • 2642562899 scopus 로고    scopus 로고
    • The neutral comet assay detects double strand DNA damage in selected and unselected human spermatozoa of normospermic donors
    • Van Kooij RJ, de Boer P. De Vreeden-Elbertse JM, Ganga NA, Singh N, Te Velde ER. The neutral comet assay detects double strand DNA damage in selected and unselected human spermatozoa of normospermic donors. Int J Androl 2004:27:140-146.
    • (2004) Int J Androl , vol.27 , pp. 140-146
    • Van Kooij, R.J.1    de Boer, P.2    De Vreeden-Elbertse, J.M.3    Ganga, N.A.4    Singh, N.5    Te Velde, E.R.6
  • 54
    • 2342584714 scopus 로고    scopus 로고
    • Sperm chromatin structure assay (SCSA) parameters are related to fertilization, blastocyst development, and ongoing pregnancy in in vitro fertilization and intracytoplasmic sperm injection cycles
    • Virro MR, Larson-Cook KL, Evenson DP. Sperm chromatin structure assay (SCSA) parameters are related to fertilization, blastocyst development, and ongoing pregnancy in in vitro fertilization and intracytoplasmic sperm injection cycles. Fertil Steril 2004;81:1289-1295.
    • (2004) Fertil Steril , vol.81 , pp. 1289-1295
    • Virro, M.R.1    Larson-Cook, K.L.2    Evenson, D.P.3
  • 55
    • 4444339903 scopus 로고    scopus 로고
    • A model for the function of sperm DNA degradation
    • Ward MA, Ward WS. A model for the function of sperm DNA degradation. Reprod Fertil Dev 2004;16:547-554.
    • (2004) Reprod Fertil Dev , vol.16 , pp. 547-554
    • Ward, M.A.1    Ward, W.S.2
  • 57
    • 33845604556 scopus 로고    scopus 로고
    • DNA double-strand break repair: All's well that ends well
    • Wyman C, Kanaar R. DNA double-strand break repair: All's well that ends well. Annu.Rev.Genet. 2006;40:363-383.
    • (2006) Annu.Rev.Genet , vol.40 , pp. 363-383
    • Wyman, C.1    Kanaar, R.2
  • 58
    • 28544444402 scopus 로고    scopus 로고
    • Potential adverse effect of sperm DNA damage on embryo quality after ICSI
    • Zini A, Meriano J. Kader K, Jarvi K, Laskin CA, Cadesky K. Potential adverse effect of sperm DNA damage on embryo quality after ICSI. Hum Reprod 2005;20:3476-3480.
    • (2005) Hum Reprod , vol.20 , pp. 3476-3480
    • Zini, A.1    Meriano, J.2    Kader, K.3    Jarvi, K.4    Laskin, C.A.5    Cadesky, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.