Identification of a new specific Kv1.3 channel blocker, Ctri9577, from the scorpion Chaerilus tricostatus

Peptides

Volumn 36, Issue 1, 2012, Pages 94-99

  Xie, Shujun ^a   Feng, Jing ^a   Yu, Congya ^a   Li, Zhi ^a   Wu, Yingliang ^a   Cao, Zhijian ^a   Li, Wenxin ^a   He, Xiaohua ^a   Xiang, Ming ^b   Han, Song ^a  

^a WUHAN UNIVERSITY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

KTx; Autoimmune diseases; Chaerilus tricostatus; Ctri9577; Kv1.3 channel

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; CTRI 9577; CYSTEINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KV1.1; POTASSIUM CHANNEL KV1.2; POTASSIUM CHANNEL SK3; SCORPION VENOM; UNCLASSIFIED DRUG;

ARTICLE; CHAERILUS TRICOSTATUS; DNA LIBRARY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG PURIFICATION; DRUG STRUCTURE; IC 50; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SCORPION; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; HEK293 CELLS; HUMANS; KV1.3 POTASSIUM CHANNEL; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PATCH-CLAMP TECHNIQUES; PHYLOGENY; POTASSIUM CHANNEL BLOCKERS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA, TRANSFER, AMINO ACYL; SCORPION VENOMS; SCORPIONS; SEQUENCE ANALYSIS, DNA;

CHAERILIDAE; CHAERILUS; SCORPIONES;

EID: 84862116420     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.04.023     Document Type: Article

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