Studies on the interactions between β2 adrenergic receptor and Gs protein by molecular dynamics simulations

Journal of Chemical Information and Modeling

Volumn 52, Issue 4, 2012, Pages 1005-1014

  Feng, Zhiwei ^a   Hou, Tingjun ^a   Li, Youyong ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; CRYSTAL STRUCTURE; MOLECULAR DYNAMICS; MUSCLE;

ACTIVATION MECHANISMS; ADRENERGIC RECEPTORS; CONFORMATIONAL CHANGE; EXTRACELLULAR REGION; G PROTEIN COUPLED RECEPTORS; MOLECULAR DYNAMICS SIMULATIONS; PHYSIOLOGICAL FUNCTIONS; WATER ENVIRONMENTS;

PROTEINS;

AMINO ACID; BENZOXAZINE DERIVATIVE; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BI167107; G PROTEIN COUPLED RECEPTOR; LIPID; NANOBODY; PROTEIN BINDING; WATER;

AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL PHENOMENA; CHEMISTRY; HUMAN; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR GENETICS; PROTEIN CONFORMATION; STATIC ELECTRICITY; THERMODYNAMICS; ARTICLE; PROTEIN BINDING;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; AMINO ACID SEQUENCE; AMINO ACIDS; BENZOXAZINES; BINDING SITES; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SINGLE-DOMAIN ANTIBODIES; STATIC ELECTRICITY; THERMODYNAMICS; WATER;

EID: 84862027158     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci200594d     Document Type: Article

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