Relation of Trp64Arg polymorphism of beta 3-adrenergic receptor gene to adipocytokines and fat distribution in obese patients

Annals of Nutrition and Metabolism

Volumn 52, Issue 4, 2008, Pages 267-271

  De Luis, D A ^a   Aller, R ^a   Izaola, O ^a   Gonzalez Sagrado, M ^a   Conde, R ^a  

^a UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

Adipocytokines; Obesity; Trp64Arg polymorphism, beta 3 adrenergic receptor gene

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; ARGININE; BETA 3 ADRENERGIC RECEPTOR; C REACTIVE PROTEIN; LEPTIN; RESISTIN; TRYPTOPHAN;

ADULT; ARTICLE; BLOOD PRESSURE; DIETARY INTAKE; FEMALE; GENE INTERACTION; GENETIC POLYMORPHISM; GENOTYPE; HEREDITY; HUMAN; INSULIN RESISTANCE; LIPID STORAGE; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; OBESITY; PRIORITY JOURNAL; RECEPTOR GENE; WAIST CIRCUMFERENCE; WEIGHT;

ADIPOKINES; ADIPONECTIN; ADULT; BLOOD GLUCOSE; BODY FAT DISTRIBUTION; C-REACTIVE PROTEIN; CALORIMETRY, INDIRECT; CHOLESTEROL; DIET; FEMALE; GENOTYPE; HUMANS; INSULIN RESISTANCE; LEPTIN; MALE; MUTATION, MISSENSE; OBESITY; POLYMORPHISM, GENETIC; PROSPECTIVE STUDIES; RECEPTORS, ADRENERGIC, BETA-3; RESISTIN;

EID: 51349092849     PISSN: 02506807     EISSN: None     Source Type: Journal    
DOI: 10.1159/000144047     Document Type: Article

References (22)

1. Rosenbaum M, Leibel RL, Hirsch J: Obesity. N Engl J Med 1997;337:396-407.
2. Thomas GN, Tomlinson B, Chan JC, Young RP, Critchley JA: The Trp64Arg polymorphism of the beta3-adrenergic receptor gene and obesity in Chinese subjects with components of the metabolic syndrome. Int J Obes Relat Metab Disord 2000;24:545-551.
3. Tchernof A, Starling RD, Walston JD, Shuldiner AR, Dvorack RV, Silver K, Matthews DE, Poehlman ET: Obesity-related phenotypes and the beta3-adrenoceptor gene variant in postmenopausal women. Diabetes 1999;48:1425-1428.
4. Matsuda M, Shimomura I, Sata M, Arita Y, Nishida M, Maeda N, Kumada M, Okamoto Y, Nagaretani H, Nishizawa H, Kishida K, Komuro R, Ouchi N, Kihara S, Nagai R, Funahashi T, Matsuzawa Y: Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem 2002;277:37487-37491.
5. Kumada M, Kihara S, Sumitsuji S, Kawamoto T, Matsumoto S, Ouchi N, Arita Y, Okamoto Y, Shimomura I, Hiraoka H, Nakamura T, Funahashi T, Matsuzawa Y; Osaka CAD Study Group - coronary artery disease: Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 2003;23:85-89.
6. Shimomura I, Hammer RE, Ikemoto S, Brown MS, Goldstein JL: Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 1999;401:73-76.
7. Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, Lazar MA: The hormone resistin links obesity to diabetes. Nature 2001;409:307-312.
8. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419.
9. Feurer ID, Mullen JL: Bedside measurement of resting energy expenditure and respiratory quotient via indirect calorimetry. Nutr Clin Pract 1986;1:43-49.
10. Pichard C, Slosman D, Hirschel B, Kyle U: Bioimpedance analysis in AIDS patients: an improved method for nutritional follow-up (abstract). Clin Res 1993;41:53.
11. Mataix J, Mañas M: Tablas de composición de alimentos españoles. Granada, Universidad de Granada, 2003.
12. Yoshida T, Sakane N, Umekawa T, Sakai M, Takahashi T, Kondo M: Mutation of beta 3-adrenergic-receptor gene and response to treatment of obesity. Lancet 1995;346:1433-1434.
13. Urhammer SA, Clausen JO, Hansen T, Pedersen O: Insulin sensitivity and body weight changes in young white carriers of the codon 64 amino acid polymorphism of the beta 3-adrenergic receptor gene. Diabetes 1996;45:1115-1120.
14. Fujisawa T, Ikegami H, Kawaguchi Y, Ogihara T: Meta-analysis of the association of Trp64Arg polymorphism of beta 3-adrenergic receptor gene with body mass index. J Clin Endocrinol Metab 1998;83:2441-2444.
15. Sakane N, Yoshida T, Umekawa T, Kondo M, Sakai Y, Takakashi T: Beta 3-adrenergic-receptor polymorphism: a genetic marker for visceral fat obesity and the insulin resistance syndrome. Diabetologia 1997:40:200-204.
16. Allison DB, Heo M, Faith MS, Pietrobelli A: Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with body mass index. Int J Obes Relat Metab Disord 1998;22:559-566.
17. Susulic VS, Frederich RC, Lawitts J, Tozzo E, Kahn BB, Harper ME, Himms-Hagen J, Flier JS, Lowell BB: Targeted disruption of the beta 3-adrenergic receptor gene. J Biol Chem 1995;270:29483-29492.
18. Hoffstedt J, Wahrenberg H, Thörne A, Lönnqvist F: The metabolic syndrome is related to beta 3-adrenoceptor sensitivity in vis ceral adipose tissue. Diabetologia 1996;39:838-844.
19. Kim-Motoyama H, Yasuda K, Yamaguchi T, Yamada N, Katakura T, Shuldiner AR, Akanuma Y, Ohashi Y, Yazaki Y, Kadowaki T: A mutation of the beta 3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride. Diabetologia 1997;40:469-472.
20. Silha JV, Krsek M, Skrha JV, Sucharda P, Nyomba BL, Murphy LJ: Plasma resistin, adiponectin and leptin levels in lean and obese subjects: correlations with insulin resistance. Eur J Endocrinol 2003;149:331-335.
21. Ceddia RB, Koistinen HA, Zierath JR, Sweeney G: Analysis of paradoxical observations on the association between leptin and insulin resistance. FASEB J 2002;16:1163-1176.
22. Leineweber K, Büscher R, Bruck H, Brodde OE: Beta-adrenoceptor polymorphisms. Naunyn Schmiedebergs Arch Pharmacol 2004;369:1-22.