메뉴 건너뛰기




Volumn 83, Issue 4, 2009, Pages 663-671

Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression

Author keywords

AAV vectors; Angiogenesis; Gene therapy; VEGF; Vessel maturation

Indexed keywords

DOXYCYCLINE; PARVOVIRUS VECTOR; TRANSACTIVATOR PROTEIN; VASCULOTROPIN;

EID: 68949163249     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp152     Document Type: Article
Times cited : (63)

References (39)
  • 1
    • 30744432619 scopus 로고    scopus 로고
    • Endothelial cells and VEGF in vascular development
    • Coultas L, Chawengsaksophak K, Rossant J. Endothelial cells and VEGF in vascular development. Nature 2005;438:937-945.
    • (2005) Nature , vol.438 , pp. 937-945
    • Coultas, L.1    Chawengsaksophak, K.2    Rossant, J.3
  • 2
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005;438:932-936.
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 3
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003;9:669-676.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 4
    • 34249689753 scopus 로고    scopus 로고
    • Molecular regulation of angiogenesis and lymphangiogenesis
    • Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol 2007;8:464-478.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 464-478
    • Adams, R.H.1    Alitalo, K.2
  • 6
    • 10744223300 scopus 로고    scopus 로고
    • Coordinated activation of VEGFR-1 and VEGFR-2 is a potent arteriogenic stimulus leading to enhancement of regional perfusion
    • Babiak A, Schumm AM, Wangler C, Loukas M, Wu J, Dombrowski S et al. Coordinated activation of VEGFR-1 and VEGFR-2 is a potent arteriogenic stimulus leading to enhancement of regional perfusion. Cardiovasc Res 2004;61:789-795.
    • (2004) Cardiovasc Res , vol.61 , pp. 789-795
    • Babiak, A.1    Schumm, A.M.2    Wangler, C.3    Loukas, M.4    Wu, J.5    Dombrowski, S.6
  • 7
    • 34250772826 scopus 로고    scopus 로고
    • Current status of cardiovascular gene therapy
    • Rissanen TT, Yla-Herttuala S. Current status of cardiovascular gene therapy. Mol Ther 2007;15:1233-1247.
    • (2007) Mol Ther , vol.15 , pp. 1233-1247
    • Rissanen, T.T.1    Yla-Herttuala, S.2
  • 8
    • 0343632352 scopus 로고    scopus 로고
    • Tsurumi Y, Kearney M, Chen D, Silver M, Takeshita S, Yang J et al. Treatment of acute limb ischemia by intramuscular injection of vascular endothelial growth factor gene. Circulation 1997;96:II-382-388.
    • Tsurumi Y, Kearney M, Chen D, Silver M, Takeshita S, Yang J et al. Treatment of acute limb ischemia by intramuscular injection of vascular endothelial growth factor gene. Circulation 1997;96:II-382-388.
  • 9
    • 0037790710 scopus 로고    scopus 로고
    • Molecular basis of the inflammatory response to adenovirus vectors
    • Liu Q, Muruve DA. Molecular basis of the inflammatory response to adenovirus vectors. Gene Ther 2003;10:935-940.
    • (2003) Gene Ther , vol.10 , pp. 935-940
    • Liu, Q.1    Muruve, D.A.2
  • 10
    • 18744367228 scopus 로고    scopus 로고
    • Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle
    • Gounis MJ, Spiga MG, Graham RM, Wilson A, Haliko S, Lieber BB et al. Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle. Gene Ther 2005;12:762-771.
    • (2005) Gene Ther , vol.12 , pp. 762-771
    • Gounis, M.J.1    Spiga, M.G.2    Graham, R.M.3    Wilson, A.4    Haliko, S.5    Lieber, B.B.6
  • 11
    • 0038365573 scopus 로고    scopus 로고
    • Localized arteriole formation directly adjacent to the site of VEGF-induced angiogenesis in muscle
    • Springer ML, Ozawa CR, Banfi A, Kraft PE, Ip TK, Brazelton TR et al. Localized arteriole formation directly adjacent to the site of VEGF-induced angiogenesis in muscle. Mol Ther 2003;7:441-449.
    • (2003) Mol Ther , vol.7 , pp. 441-449
    • Springer, M.L.1    Ozawa, C.R.2    Banfi, A.3    Kraft, P.E.4    Ip, T.K.5    Brazelton, T.R.6
  • 12
    • 85047694677 scopus 로고    scopus 로고
    • Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis
    • Ozawa CR, Banfi A, Glazer NL, Thurston G, Springer ML, Kraft PE et al. Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis. J Clin Invest 2004;113:516-527.
    • (2004) J Clin Invest , vol.113 , pp. 516-527
    • Ozawa, C.R.1    Banfi, A.2    Glazer, N.L.3    Thurston, G.4    Springer, M.L.5    Kraft, P.E.6
  • 13
    • 0036196808 scopus 로고    scopus 로고
    • AAV-mediated VEGF gene transfer into skeletal muscle stimulates angio-genesis and improves blood flow in a rat hindlimb ischemia model
    • Shimpo M, Ikeda U, Maeda Y, Takahashi M, Miyashita H, Mizukami H et al. AAV-mediated VEGF gene transfer into skeletal muscle stimulates angio-genesis and improves blood flow in a rat hindlimb ischemia model. Cardiovasc Res 2002;53:993-1001.
    • (2002) Cardiovasc Res , vol.53 , pp. 993-1001
    • Shimpo, M.1    Ikeda, U.2    Maeda, Y.3    Takahashi, M.4    Miyashita, H.5    Mizukami, H.6
  • 14
    • 0037689525 scopus 로고    scopus 로고
    • Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors
    • Arsic N, Zentilin L, Zacchigna S, Santoro D, Stanta G, Salvi S et al. Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors. Mol Ther 2003;7:450-459.
    • (2003) Mol Ther , vol.7 , pp. 450-459
    • Arsic, N.1    Zentilin, L.2    Zacchigna, S.3    Santoro, D.4    Stanta, G.5    Salvi, S.6
  • 15
    • 33646128955 scopus 로고    scopus 로고
    • Adeno-Associated Virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs
    • Ferrarini M, Arsic N, Recchia FA, Zentilin L, Zacchigna S, Xu X et al. Adeno-Associated Virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs. Circ Res 2006;98:954-961.
    • (2006) Circ Res , vol.98 , pp. 954-961
    • Ferrarini, M.1    Arsic, N.2    Recchia, F.A.3    Zentilin, L.4    Zacchigna, S.5    Xu, X.6
  • 16
    • 0037926778 scopus 로고    scopus 로고
    • Dvorak HF. Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma. Am J Pathol 2003;162:1747-1757.
    • Dvorak HF. Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma. Am J Pathol 2003;162:1747-1757.
  • 17
    • 34447126305 scopus 로고    scopus 로고
    • In vivo imaging shows abnormal function of vascular endothelial growth factor-induced vasculature
    • Zacchigna S, Tasciotti E, Kusmic C, Arsic N, Sorace O, Marini C et al. In vivo imaging shows abnormal function of vascular endothelial growth factor-induced vasculature. Hum Gene Ther 2007;18:515-524.
    • (2007) Hum Gene Ther , vol.18 , pp. 515-524
    • Zacchigna, S.1    Tasciotti, E.2    Kusmic, C.3    Arsic, N.4    Sorace, O.5    Marini, C.6
  • 20
    • 0034581163 scopus 로고    scopus 로고
    • Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances
    • Baron U, Bujard H. Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances. Methods Enzymol 2000;327:401-421.
    • (2000) Methods Enzymol , vol.327 , pp. 401-421
    • Baron, U.1    Bujard, H.2
  • 21
    • 0035194442 scopus 로고    scopus 로고
    • Involvement of cellular double-strand DNA break-binding proteins in processing of recombinant adenoassociated virus (AAV) genome
    • Zentilin L, Marcello A, Giacca M. Involvement of cellular double-strand DNA break-binding proteins in processing of recombinant adenoassociated virus (AAV) genome. J Virol 2001;75:12279-12287.
    • (2001) J Virol , vol.75 , pp. 12279-12287
    • Zentilin, L.1    Marcello, A.2    Giacca, M.3
  • 22
    • 33646433695 scopus 로고    scopus 로고
    • Bone marrow mononuclear cells are recruited to the sites of VEGF-induced neovascularization but are not incorporated into the newly formed vessels
    • Zentilin L, Tafuro S, Zacchigna S, Arsic N, Pattarini L, Sinigaglia M et al. Bone marrow mononuclear cells are recruited to the sites of VEGF-induced neovascularization but are not incorporated into the newly formed vessels. Blood 2006;107:3546-3554.
    • (2006) Blood , vol.107 , pp. 3546-3554
    • Zentilin, L.1    Tafuro, S.2    Zacchigna, S.3    Arsic, N.4    Pattarini, L.5    Sinigaglia, M.6
  • 23
    • 45749092525 scopus 로고    scopus 로고
    • Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis
    • Zacchigna S, Pattarini L, Zentilin L, Moimas S, Carrer A, Sinigaglia M et al. Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis. J Clin Invest 2008;118:2062-2075.
    • (2008) J Clin Invest , vol.118 , pp. 2062-2075
    • Zacchigna, S.1    Pattarini, L.2    Zentilin, L.3    Moimas, S.4    Carrer, A.5    Sinigaglia, M.6
  • 25
    • 0033012871 scopus 로고    scopus 로고
    • Macrophages kill capillary cells in G1 phase of the cell cycle during programmed vascular regression
    • Diez-Roux G, Argilla M, Makarenkova H, Ko K, Lang RA. Macrophages kill capillary cells in G1 phase of the cell cycle during programmed vascular regression. Development 1999;126:2141-2147.
    • (1999) Development , vol.126 , pp. 2141-2147
    • Diez-Roux, G.1    Argilla, M.2    Makarenkova, H.3    Ko, K.4    Lang, R.A.5
  • 27
    • 34250739823 scopus 로고    scopus 로고
    • Histone modifications are associated with the persistence or silencing of vector-mediated transgene expression in vivo
    • Riu E, Chen ZY, Xu H, He CY, Kay MA. Histone modifications are associated with the persistence or silencing of vector-mediated transgene expression in vivo. Mol Ther 2007;15:1348-1355.
    • (2007) Mol Ther , vol.15 , pp. 1348-1355
    • Riu, E.1    Chen, Z.Y.2    Xu, H.3    He, C.Y.4    Kay, M.A.5
  • 28
    • 33645212833 scopus 로고    scopus 로고
    • Plasmid DNA sequences present in conventional herpes simplex virus amplicon vectors cause rapid transgene silencing by forming inactive chromatin
    • Suzuki M, Kasai K, Saeki Y. Plasmid DNA sequences present in conventional herpes simplex virus amplicon vectors cause rapid transgene silencing by forming inactive chromatin. J Virol 2006;80:3293-3300.
    • (2006) J Virol , vol.80 , pp. 3293-3300
    • Suzuki, M.1    Kasai, K.2    Saeki, Y.3
  • 30
    • 0032170592 scopus 로고    scopus 로고
    • Control of erythropoietin delivery by doxycycline in mice after intramuscular injection of adeno-associated vector
    • Bohl D, Salvetti A, Moullier P, Heard JM. Control of erythropoietin delivery by doxycycline in mice after intramuscular injection of adeno-associated vector. Blood 1998;92:1512-1517.
    • (1998) Blood , vol.92 , pp. 1512-1517
    • Bohl, D.1    Salvetti, A.2    Moullier, P.3    Heard, J.M.4
  • 31
    • 0031879481 scopus 로고    scopus 로고
    • Regulation of gene expression in vivo following transduction by two separate rAAV vectors
    • Rendahl KG, Leff SE, Otten GR, Spratt SK, Bohl D, Van Roey M et al. Regulation of gene expression in vivo following transduction by two separate rAAV vectors. Nat Biotechnol 1998;16:757-761.
    • (1998) Nat Biotechnol , vol.16 , pp. 757-761
    • Rendahl, K.G.1    Leff, S.E.2    Otten, G.R.3    Spratt, S.K.4    Bohl, D.5    Van Roey, M.6
  • 32
    • 0032862285 scopus 로고    scopus 로고
    • Concatamerization of adeno-associated virus circular genomes occurs through intermolecular recombination
    • Yang J, Zhou W, Zhang Y, Zidon T, Ritchie T, Engelhardt JF. Concatamerization of adeno-associated virus circular genomes occurs through intermolecular recombination. J Virol 1999;73:9468-9477.
    • (1999) J Virol , vol.73 , pp. 9468-9477
    • Yang, J.1    Zhou, W.2    Zhang, Y.3    Zidon, T.4    Ritchie, T.5    Engelhardt, J.F.6
  • 33
    • 0036827724 scopus 로고    scopus 로고
    • Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus
    • Favre D, Blouin V, Provost N, Spisek R, Porrot F, Bohl D et al. Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus. J Virol 2002;76:11605-11611.
    • (2002) J Virol , vol.76 , pp. 11605-11611
    • Favre, D.1    Blouin, V.2    Provost, N.3    Spisek, R.4    Porrot, F.5    Bohl, D.6
  • 34
    • 33645840126 scopus 로고    scopus 로고
    • Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors
    • Stieger K, Le Meur G, Lasne F, Weber M, Deschamps JY, Nivard D et al. Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors. Mol Ther 2006;13:967-975.
    • (2006) Mol Ther , vol.13 , pp. 967-975
    • Stieger, K.1    Le Meur, G.2    Lasne, F.3    Weber, M.4    Deschamps, J.Y.5    Nivard, D.6
  • 35
    • 0037090776 scopus 로고    scopus 로고
    • Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy
    • Dor Y, Djonov V, Abramovitch R, Itin A, Fishman GI, Carmeliet P et al. Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J 2002;21:1939-1947.
    • (2002) EMBO J , vol.21 , pp. 1939-1947
    • Dor, Y.1    Djonov, V.2    Abramovitch, R.3    Itin, A.4    Fishman, G.I.5    Carmeliet, P.6
  • 36
    • 0035049231 scopus 로고    scopus 로고
    • Thrombospondins as matricellular modulators of cell function
    • Bornstein P. Thrombospondins as matricellular modulators of cell function. J Clin Invest 2001;107:929-934.
    • (2001) J Clin Invest , vol.107 , pp. 929-934
    • Bornstein, P.1
  • 37
    • 30344440869 scopus 로고    scopus 로고
    • Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly
    • Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N et al. Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell 2006;124:161-173.
    • (2006) Cell , vol.124 , pp. 161-173
    • Foo, S.S.1    Turner, C.J.2    Adams, S.3    Compagni, A.4    Aubyn, D.5    Kogata, N.6
  • 38
    • 0031058024 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus for muscle directed gene therapy
    • Fisher KJ, Jooss K, Alston J, Yang Y, Haecker SE, High K et al. Recombinant adeno-associated virus for muscle directed gene therapy. Nat Med 1997;3:306-312.
    • (1997) Nat Med , vol.3 , pp. 306-312
    • Fisher, K.J.1    Jooss, K.2    Alston, J.3    Yang, Y.4    Haecker, S.E.5    High, K.6
  • 39
    • 0033023881 scopus 로고    scopus 로고
    • Structure of adeno-associated virus vector DNA following transduction of the skeletal muscle
    • Vincent-Lacaze N, Snyder RO, Gluzman R, Bohl D, Lagarde C, Danos O. Structure of adeno-associated virus vector DNA following transduction of the skeletal muscle. J Virol 1999;73:1949-1955.
    • (1999) J Virol , vol.73 , pp. 1949-1955
    • Vincent-Lacaze, N.1    Snyder, R.O.2    Gluzman, R.3    Bohl, D.4    Lagarde, C.5    Danos, O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.