Vascular endothelial growth factor: Gene therapy and therapeutic angiogenesis

American Journal of Cardiology

Volumn 82, Issue 9 SUPPL. 2, 1998, Pages 63S-64S

  Isner, Jeffrey M ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST ELIZABETH'S MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; COLLATERAL CIRCULATION; CONFERENCE PAPER; GENE TARGETING; GENE THERAPY; HUMAN; PRIORITY JOURNAL; THROMBOSIS; VASCULAR ENDOTHELIUM;

ANIMALS; ENDOTHELIAL GROWTH FACTORS; GENE THERAPY; HUMANS; ISCHEMIA; LYMPHOKINES; NEOVASCULARIZATION, PHYSIOLOGIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0032548023     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(98)00764-4     Document Type: Article

References (5)

1. Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989;246: 1306-1309.
2. Tsurumi Y, Murohara T, Krasinski K, Chen D, Witzenbichler B, Kearney M, Couffinhal T, Isner JM. Reciprocal relation between VEGF and NO in the regulation of endothelial integrity. Nature Med 1997;3:879-886.
3. Takeshita S, Zheng LP, Brogi E, Kearney M, Pu L-Q, Bunting S, Ferrara N, Symes JF, Isner JM. Therapeutic angiogenesis: a single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J Clin Invest 1994;93:662-670.
4. 165 inhibits thrombus formation and intimal thickening. J Am Coll Cardiol 1997;29:1371-1379.
5. 165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 1998;97:1114-1123.