Post-translational regulated and hypoxia-responsible VEGF plasmid for efficient secretion

Journal of Controlled Release

Volumn 160, Issue 3, 2012, Pages 525-531

  Won, Young Wook ^a   Lee, Minhyung ^b   Kim, Hyun Ah ^b   Bull, David A ^c   Kim, Sung Wan ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b Hanyang University   (South Korea)

^c UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

Gene therapy; Hypoxia; Myocardial ischemia; VEGF

Indexed keywords

FUSION PROTEINS; HYPOXIA; HYPOXIC CONDITION; MYOCARDIAL ISCHEMIA; NORMOXIC CONDITIONS; RECOGNITION SITE; SECRETION EFFICIENCY; SIDE EFFECT; SIGNAL PEPTIDE; TARGET CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR; VEGF; WILD TYPES;

DEGRADATION; DNA; ENDOTHELIAL CELLS; GENE EXPRESSION; GENE THERAPY; PROTEINS;

PHYSIOLOGY;

HYBRID PROTEIN; SIGNAL PEPTIDE; VASCULOTROPIN;

ARTICLE; HUMAN; HUMAN CELL; HYPOXIA; OXYGEN DEPENDENT DEGRADATION DOMAIN; PLASMID; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANIMALS; ANOXIA; CELL LINE; CELLS, CULTURED; COBALT; DNA, COMPLEMENTARY; FURIN; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; PEPTIDES; PLASMIDS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; RATS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VENOMS;

EID: 84861980306     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.03.010     Document Type: Article

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