Gene therapy of neural cell injuries in vitro using the hypoxia-inducible GM-CSF expression plasmids and water-soluble lipopolymer (WSLP)

Journal of Controlled Release

Volumn 133, Issue 1, 2009, Pages 60-67

  Kim, Jin Mo ^a   Lee, Minhyung ^b   Kim, Kil Hwan ^a   Ha, Yoon ^a   Choi, Jung Kyoung ^a   Park, So Ra ^a   Park, Hyeonseon ^a   Park, Hyung Chun ^a   Ahn, Cheol Hee ^c   Kim, Sung Wan ^d   Choi, Byung Hyune ^a  

^a Inha University School of Medicine   (South Korea)

^b Hanyang University   (South Korea)

^c Seoul National University   (South Korea)

^d UNIVERSITY OF UTAH   (United States)

Author keywords

Gene therapy; Granulocyte macrophage colony stimulating factor (GM CSF); Hypoxia inducible system; Neural cells; Water soluble lipopolymer (WSLP)

Indexed keywords

CELL DEATH; CELLS; CIVIL AVIATION; CYTOLOGY; GENE TRANSFER; GENETIC ENGINEERING; GRANULAR MATERIALS; MACROPHAGES; NUCLEIC ACIDS; POLYMERS; VECTORS;

ANIMAL MODELS; BIOCOMPATIBLE POLYMERS; GENE DELIVERIES; GENE DELIVERY CARRIERS; GENE THERAPIES; GENE THERAPY; GENE TRANSFECTIONS; GRANULOCYTE MACROPHAGES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF); HYPOXIA-INDUCIBLE SYSTEM; IN VITRO; INDUCIBLE EXPRESSIONS; INDUCIBLE SYSTEMS; LIPO POLYMERS; LIPOFECTAMINE; LUCIFERASE REPORTERS; NEURAL CELLS; NEURAL PROGENITOR CELLS; NEURAL SYSTEMS; NEUROBLASTOMA CELL LINES; NEUROPROTECTIVE EFFECTS; POLYETHYLENIMINE; POLYMERIC GENE CARRIERS; PRIMARY CULTURES; TRANSFECTION EFFICIENCIES;

CELL CULTURE;

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LIPOFECTAMINE; POLYETHYLENEIMINE; POLYMER;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NERVE CELL LESION; NEUROBLASTOMA CELL; NEUROPROTECTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD INJURY; STEM CELL;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL HYPOXIA; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; ERYTHROPOIETIN; GENE EXPRESSION; GENE THERAPY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; GREEN FLUORESCENT PROTEINS; HUMANS; LIPIDS; LUCIFERASES; MICE; MICE, INBRED ICR; MICROSCOPY, FLUORESCENCE; NEURONS; PLASMIDS; POLYETHYLENEIMINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAUROSPORINE; TRANSFECTION;

EID: 57049109244     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.09.080     Document Type: Article

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