-
1
-
-
67449119913
-
The endocannabinoid system: Its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation
-
Di Marzo, V. (2009) The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation. Pharmacol. Res. 60, 77-84
-
(2009)
Pharmacol. Res.
, vol.60
, pp. 77-84
-
-
Di Marzo, V.1
-
2
-
-
43249100162
-
Targeting the endocannabinoid system: To enhance or reduce?
-
Di Marzo, V. (2008) Targeting the endocannabinoid system: to enhance or reduce? Nat. Rev. Drug Discov. 7, 438-455
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 438-455
-
-
Di Marzo, V.1
-
3
-
-
0036838392
-
Cardiovascular system effects of marijuana
-
Jones, R.T. (2002) Cardiovascular system effects of marijuana. J. Clin. Pharmacol. 42, 58S-63S
-
(2002)
J. Clin. Pharmacol.
, vol.42
-
-
Jones, R.T.1
-
4
-
-
0030925426
-
1-like cannabinoid receptors
-
Lake, K.D. et al. (1997) Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. J. Pharmacol. Exp. Ther. 281, 1030-1037 (Pubitemid 27258357)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.281
, Issue.3
, pp. 1030-1037
-
-
Lake, K.D.1
Compton, D.R.2
Varga, K.3
Martin, B.R.4
Kunos, G.5
-
5
-
-
0031773354
-
Cardiovascular actions of cannabinoids and their generation during shock
-
Wagner, J.A. et al. (1998) Cardiovascular actions of cannabinoids and their generation during shock. J. Mol. Med. (Berl.) 76, 824-836 (Pubitemid 28518708)
-
(1998)
Journal of Molecular Medicine
, vol.76
, Issue.12
, pp. 824-836
-
-
Wagner, J.A.1
Varga, K.2
Kunos, G.3
-
6
-
-
23744439061
-
Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase
-
DOI 10.1152/ajpheart.00107.2005
-
Pacher, P. et al. (2005) Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase. Am. J. Physiol. Heart Circ. Physiol. 289, H533-H541 (Pubitemid 41129366)
-
(2005)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.289
, Issue.2
-
-
Pacher, P.1
Batkai, S.2
Osei-Hyiaman, D.3
Offertaler, L.4
Liu, J.5
Harvey-White, J.6
Brassai, A.7
Jarai, Z.8
Cravatt, B.F.9
Kunos, G.10
-
7
-
-
0035210486
-
1 receptor-mediated changes in heart rate and blood pressure in anaesthetized rats
-
DOI 10.1007/s00210-001-0498-6
-
Malinowska, B. et al. (2001) Anandamide and methanandamide induce both vanilloid VR1- and cannabinoid CB1 receptor-mediated changes in heart rate and blood pressure in anaesthetized rats. Naunyn Schmiedebergs Arch. Pharmacol. 364, 562-569 (Pubitemid 33145097)
-
(2001)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.364
, Issue.6
, pp. 562-569
-
-
Malinowska, B.1
Kwolek, G.2
Gothert, M.3
-
8
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
DOI 10.1038/22761
-
Zygmunt, P.M. et al. (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400, 452-457 (Pubitemid 29361798)
-
(1999)
Nature
, vol.400
, Issue.6743
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.-H.4
Sorgard, M.5
Di, M.V.6
Julius, D.7
Hogestatt, E.D.8
-
9
-
-
1642430679
-
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
-
Jordt, S.E. et al. (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427, 260-265
-
(2004)
Nature
, vol.427
, pp. 260-265
-
-
Jordt, S.E.1
-
10
-
-
1442315642
-
Cannabinoid pharmacology in the cardiovascular system: Potential protective mechanisms through lipid signalling
-
DOI 10.1017/S1464793103006201
-
Hiley, C.R. and Ford, W.R. (2004) Cannabinoid pharmacology in the cardiovascular system: potential protective mechanisms through lipid signalling. Biol. Rev. Camb. Philos. Soc. 79, 187-205 (Pubitemid 38282051)
-
(2004)
Biological Reviews of the Cambridge Philosophical Society
, vol.79
, Issue.1
, pp. 187-205
-
-
Hiley, C.R.1
Ford, W.R.2
-
11
-
-
0035816432
-
1 receptors
-
DOI 10.1016/S0014-2999(01)01112-8, PII S0014299901011128
-
Wagner, J.A. et al. (2001) Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB1 receptors. Eur. J. Pharmacol. 423, 203-210 (Pubitemid 32614159)
-
(2001)
European Journal of Pharmacology
, vol.423
, Issue.2-3
, pp. 203-210
-
-
Wagner, J.A.1
Jarai, Z.2
Batkai, S.3
Kunos, G.4
-
12
-
-
0038845604
-
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors
-
Járai, Z. et al. (1999) Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc. Natl. Acad. Sci. U.S.A. 96, 14136-14141
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 14136-14141
-
-
Járai, Z.1
-
13
-
-
34247218666
-
Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in wistar rats fed a high-salt diet
-
DOI 10.1124/jpet.106.112904
-
Wang, Y. et al. (2007) Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. J. Pharmacol. Exp. Ther. 321, 763-769 (Pubitemid 46624495)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.2
, pp. 763-769
-
-
Wang, Y.1
Kaminski, N.E.2
Wang, D.H.3
-
14
-
-
20144379143
-
Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: Role of cannabinoid and vanilloid receptors
-
DOI 10.1136/gut.2004.051599
-
Domenicali, M. et al. (2005) Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: role of cannabinoid and vanilloid receptors. Gut 54, 522-527 (Pubitemid 40395505)
-
(2005)
Gut
, vol.54
, Issue.4
, pp. 522-527
-
-
Domenicali, M.1
Ros, J.2
Fernandez-Varo, G.3
Cejudo-Martin, P.4
Crespo, M.5
Morales-Ruiz, M.6
Briones, A.M.7
Campistol, J.-M.8
Arroyo, V.9
Vila, E.10
Rodes, J.11
Jimenez, W.12
-
15
-
-
0242610876
-
h
-
Ray, A.M. et al. (2003) Capsazepine protects against neuronal injury caused by oxygen glucose deprivation by inhibiting Ih. J. Neurosci. 23, 10146-10153 (Pubitemid 37392563)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.31
, pp. 10146-10153
-
-
Ray, A.M.1
Benham, C.D.2
Roberts, J.C.3
Gill, C.H.4
Lanneau, C.5
Gitterman, D.P.6
Harries, M.7
Davis, J.B.8
Davies, C.H.9
-
16
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent, C. et al. (1999) Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283, 401-404
-
(1999)
Science
, vol.283
, pp. 401-404
-
-
Ledent, C.1
-
17
-
-
34548608480
-
2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis
-
2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. Liver Int. 27, 1045-1055
-
(2007)
Liver Int.
, vol.27
, pp. 1045-1055
-
-
Yang, Y.Y.1
-
18
-
-
0033952018
-
Cardiovascular effects of 2-arachidonoyl glycerol in anesthetized mice
-
Járai, Z. et al. (2000) Cardiovascular effects of 2-arachidonoyl glycerol in anesthetized mice. Hypertension 35, 679-684 (Pubitemid 30108168)
-
(2000)
Hypertension
, vol.35
, Issue.2
, pp. 679-684
-
-
Jarai, Z.1
Wagner, J.A.2
Goparaju, S.K.3
Wang, L.4
Razdan, R.K.5
Sugiura, T.6
Zimmer, A.M.7
Bonner, T.I.8
Zimmer, A.9
Kunos, G.10
-
20
-
-
1842611872
-
Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl-dopamine (NADA)
-
DOI 10.1038/sj.bjp.0705643
-
O'Sullivan, S.E. et al. (2004) Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl-dopamine (NADA). Br. J. Pharmacol. 141, 803-812 (Pubitemid 38446181)
-
(2004)
British Journal of Pharmacology
, vol.141
, Issue.5
, pp. 803-812
-
-
O'Sullivan, S.E.1
Kendall, D.A.2
Randall, M.D.3
-
21
-
-
27144465067
-
Cardiovascular pharmacology of cannabinoids
-
Pacher, P. et al. (2005) Cardiovascular pharmacology of cannabinoids. Handb. Exp. Pharmacol. 168, 599-625
-
(2005)
Handb. Exp. Pharmacol.
, vol.168
, pp. 599-625
-
-
Pacher, P.1
-
22
-
-
78649349136
-
Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects
-
Godlewski, G. et al. (2010) Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. Chem. Biol. 17, 1256-1266
-
(2010)
Chem. Biol.
, vol.17
, pp. 1256-1266
-
-
Godlewski, G.1
-
23
-
-
33144473891
-
N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties
-
DOI 10.1073/pnas.0510676103
-
Milman, G. et al. (2006) N-Arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties. Proc. Natl. Acad. Sci. U.S.A. 103, 2428-2433 (Pubitemid 43271686)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.7
, pp. 2428-2433
-
-
Milman, G.1
Maor, Y.2
Abu-Lafi, S.3
Horowitz, M.4
Gallily, R.5
Batkai, S.6
Mo, F.-M.7
Offertaler, L.8
Pacher, P.9
Kunos, G.10
Mechoulam, R.11
-
24
-
-
67651065226
-
The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways
-
Bradshaw, H.B. et al. (2009) The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways. BMC Biochem. 10, 14
-
(2009)
BMC Biochem.
, vol.10
, pp. 14
-
-
Bradshaw, H.B.1
-
25
-
-
77952609532
-
N-Arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels
-
Parmar, N. and Ho, W.S. (2010) N-Arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels. Br. J. Pharmacol. 160, 594-603
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 594-603
-
-
Parmar, N.1
Ho, W.S.2
-
26
-
-
27644586203
-
Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed
-
DOI 10.1113/jphysiol.2005.094292
-
Poblete, I.M. et al. (2005) Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed. J. Physiol. 568, 539-551 (Pubitemid 41555456)
-
(2005)
Journal of Physiology
, vol.568
, Issue.2
, pp. 539-551
-
-
Poblete, I.M.1
Orliac, M.L.2
Briones, R.3
Adler-Graschinsky, E.4
Huidobro-Toro, J.P.5
-
27
-
-
77952731052
-
N-Arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor
-
McHugh, D. et al. (2010) N-Arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor. BMC Neurosci. 11, 44
-
(2010)
BMC Neurosci.
, vol.11
, pp. 44
-
-
McHugh, D.1
-
28
-
-
57349088304
-
'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors
-
Ho, W.S. et al. (2008) 'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors. Br. J. Pharmacol. 155, 837-846
-
(2008)
Br. J. Pharmacol.
, vol.155
, pp. 837-846
-
-
Ho, W.S.1
-
29
-
-
84855527414
-
Hydrogen peroxide as a mediator of vasorelaxation evoked by N-oleoylethanolamine and anandamide in rat small mesenteric arteries
-
Wheal, A.J. et al. (2012) Hydrogen peroxide as a mediator of vasorelaxation evoked by N-oleoylethanolamine and anandamide in rat small mesenteric arteries. Eur. J. Pharmacol. 674, 384-390
-
(2012)
Eur. J. Pharmacol.
, vol.674
, pp. 384-390
-
-
Wheal, A.J.1
-
30
-
-
35648944276
-
GPR55 and the vascular receptors for cannabinoids
-
DOI 10.1038/sj.bjp.0707421, PII 0707421
-
Hiley, C.R. and Kaup, S.S. (2007) GPR55 and the vascular receptors for cannabinoids. Br. J. Pharmacol. 152, 559-561 (Pubitemid 350034976)
-
(2007)
British Journal of Pharmacology
, vol.152
, Issue.5
, pp. 559-561
-
-
Hiley, C.R.1
Kaup, S.S.2
-
31
-
-
35648959293
-
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
-
DOI 10.1038/sj.bjp.0707419, PII 0707419
-
Johns, D.G. et al. (2007) The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. Br. J. Pharmacol. 152, 825-831 (Pubitemid 350034974)
-
(2007)
British Journal of Pharmacology
, vol.152
, Issue.5
, pp. 825-831
-
-
Johns, D.G.1
Behm, D.J.2
Walker, D.J.3
Ao, Z.4
Shapland, E.M.5
Daniels, D.A.6
Riddick, M.7
Dowell, S.8
Staton, P.C.9
Green, P.10
Shabon, U.11
Bao, W.12
Aiyar, N.13
Yue, T.-L.14
Brown, A.J.15
Morrison, A.D.16
Douglas, S.A.17
-
32
-
-
4344627156
-
1 receptor knock-out mice
-
DOI 10.1113/jphysiol.2004.064824
-
Pacher, P. et al. (2004) Haemodynamic profile and responsiveness to anandamide of TRPV1 receptor knock-out mice. J. Physiol. 558, 647-657 (Pubitemid 39117608)
-
(2004)
Journal of Physiology
, vol.558
, Issue.2
, pp. 647-657
-
-
Pacher, P.1
Batkai, S.2
Kunos, G.3
-
33
-
-
34249788152
-
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury
-
DOI 10.1096/fj.06-7451com
-
Bátkai, S. et al. (2007) Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. FASEB J. 21, 1788-1800 (Pubitemid 46855625)
-
(2007)
FASEB Journal
, vol.21
, Issue.8
, pp. 1788-1800
-
-
Batkai, S.1
Osei-Hyiaman, D.2
Pan, H.3
El-Assal, O.4
Rajesh, M.5
Mukhopadhyay, P.6
Hong, F.7
Harvey-White, J.8
Jafri, A.9
Hasko, G.10
Huffman, J.W.11
Gao, B.12
Kunos, G.13
Pacher, P.14
-
34
-
-
34547160836
-
1 Cannabinoid Receptor Protects Against Doxorubicin-Induced Cardiotoxicity
-
DOI 10.1016/j.jacc.2007.03.057, PII S0735109707016257
-
Mukhopadhyay, P. et al. (2007) Pharmacological inhibition of CB1 cannabinoid receptor protects against doxorubicin-induced cardiotoxicity. J. Am. Coll. Cardiol. 50, 528-536 (Pubitemid 47126779)
-
(2007)
Journal of the American College of Cardiology
, vol.50
, Issue.6
, pp. 528-536
-
-
Mukhopadhyay, P.1
Batkai, S.2
Rajesh, M.3
Czifra, N.4
Harvey-White, J.5
Hasko, G.6
Zsengeller, Z.7
Gerard, N.P.8
Liaudet, L.9
Kunos, G.10
Pacher, P.11
-
36
-
-
11244328917
-
The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide
-
DOI 10.1124/mol.104.006353
-
Lo Verme, J. et al. (2005) The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide. Mol. Pharmacol. 67, 15-19 (Pubitemid 40069962)
-
(2005)
Molecular Pharmacology
, vol.67
, Issue.1
, pp. 15-19
-
-
Lo, V.J.1
Fu, J.2
Astarita, G.3
La, R.G.4
Russo, R.5
Calignano, A.6
Piomelli, D.7
-
37
-
-
0035881542
-
Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells
-
DOI 10.1042/0264-6021:3580249
-
Di Marzo, V. et al. (2001) Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells. Biochem. J. 358, 249-255 (Pubitemid 32778120)
-
(2001)
Biochemical Journal
, vol.358
, Issue.1
, pp. 249-255
-
-
Di, M.V.1
Melck, D.2
Orlando, P.3
Bisogno, T.4
Zagoory, O.5
Bifulco, M.6
Vogel, Z.7
De Petrocellis, L.8
-
38
-
-
0035120753
-
Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide
-
Lagneux, C. and Lamontagne, D. (2001) Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide. Br. J. Pharmacol. 132, 793-796 (Pubitemid 32193634)
-
(2001)
British Journal of Pharmacology
, vol.132
, Issue.4
, pp. 793-796
-
-
Lagneux, C.1
Lamontagne, D.2
-
39
-
-
0036023638
-
Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts
-
DOI 10.1016/S0008-6363(02)00268-7, PII S0008636302002687
-
Joyeux, M. et al. (2002) Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts. Cardiovasc. Res. 55, 619-625 (Pubitemid 34874956)
-
(2002)
Cardiovascular Research
, vol.55
, Issue.3
, pp. 619-625
-
-
Joyeux, M.1
Arnaud, C.2
Godin-Ribuot, D.3
Demenge, P.4
Lamontagne, D.5
Ribuot, C.6
-
40
-
-
63349100859
-
CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion
-
Montecucco, F. et al. (2009) CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion. J. Mol. Cell Cardiol. 46, 612-620
-
(2009)
J. Mol. Cell Cardiol.
, vol.46
, pp. 612-620
-
-
Montecucco, F.1
-
41
-
-
68549123561
-
The cannabinoid receptor type 2 promotes cardiac myocyte and fibroblast survival and protects against ischemia/reperfusion-induced cardiomyopathy
-
Defer, N. et al. (2009) The cannabinoid receptor type 2 promotes cardiac myocyte and fibroblast survival and protects against ischemia/reperfusion- induced cardiomyopathy. FASEB J. 23, 2120-2130
-
(2009)
FASEB J.
, vol.23
, pp. 2120-2130
-
-
Defer, N.1
-
42
-
-
34547100965
-
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
-
DOI 10.1152/ajpheart.00236.2007
-
Rajesh, M. et al. (2007) Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption. Am. J. Physiol. Heart Circ. Physiol. 293, H610-H619 (Pubitemid 47105122)
-
(2007)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.293
, Issue.1
-
-
Rajesh, M.1
Mukhopadhyay, P.2
Batkai, S.3
Hasko, G.4
Liaudet, L.5
Drel, V.R.6
Obrosova, I.G.7
Pacher, P.8
-
43
-
-
78649984380
-
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
-
Rajesh, M. et al. (2010) Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. J. Am. Coll. Cardiol. 56, 2115-2125
-
(2010)
J. Am. Coll. Cardiol.
, vol.56
, pp. 2115-2125
-
-
Rajesh, M.1
-
44
-
-
36849091565
-
Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury
-
DOI 10.1152/ajpheart.00098.2007
-
Durst, R. et al. (2007) Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury. Am. J. Physiol. Heart Circ. Physiol. 293, H3602-H3607 (Pubitemid 350230905)
-
(2007)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.293
, Issue.6
-
-
Durst, R.1
Danenberg, H.2
Gallily, R.3
Mechoulam, R.4
Meir, K.5
Grad, E.6
Beeri, R.7
Pugatsch, T.8
Tarsish, E.9
Lotan, C.10
-
45
-
-
0034751335
-
Molecular targets for cannabidiol and its synthetic analogues: Effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
-
Bisogno, T. et al. (2001) Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br. J. Pharmacol. 134, 845-852 (Pubitemid 33016156)
-
(2001)
British Journal of Pharmacology
, vol.134
, Issue.4
, pp. 845-852
-
-
Bisogno, T.1
Hanus, L.2
De Petrocellis, L.3
Tchilibon, S.4
Ponde, D.E.5
Brandi, I.6
Moriello, A.S.7
Davis, J.B.8
Mechoulam, R.9
Di, M.V.10
-
46
-
-
77953959767
-
Single administration of the CXC chemokine-binding protein Evasin-3 during ischemia prevents myocardial reperfusion injury in mice
-
Montecucco, F. et al. (2010) Single administration of the CXC chemokine-binding protein Evasin-3 during ischemia prevents myocardial reperfusion injury in mice. Arterioscler. Thromb. Vasc. Biol. 30, 1371-1377
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 1371-1377
-
-
Montecucco, F.1
-
47
-
-
77953198702
-
Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion
-
Walsh, S.K. et al. (2010) Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. Br. J. Pharmacol. 160, 1234-1242
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 1234-1242
-
-
Walsh, S.K.1
-
48
-
-
73049097844
-
Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner
-
Amorós, I. et al. (2010) Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner. J. Mol. Cell Cardiol. 48, 201-210
-
(2010)
J. Mol. Cell Cardiol.
, vol.48
, pp. 201-210
-
-
Amorós, I.1
-
49
-
-
38149136656
-
Atrial fibrillation and marijuana smoking
-
Korantzopoulos, P. et al. (2008) Atrial fibrillation and marijuana smoking. Int. J. Clin. Pract. 62, 308-313
-
(2008)
Int. J. Clin. Pract.
, vol.62
, pp. 308-313
-
-
Korantzopoulos, P.1
-
50
-
-
0032563825
-
Doxorubicin-induced cardiomyopathy
-
DOI 10.1056/NEJM199809243391307
-
Singal, P.K. and Iliskovic, N. (1998) Doxorubicin-induced cardiomyopathy. N. Engl. J. Med. 339, 900-905 (Pubitemid 28446849)
-
(1998)
New England Journal of Medicine
, vol.339
, Issue.13
, pp. 900-905
-
-
Singal, P.K.1
Iliskovic, N.2
-
51
-
-
70450260555
-
Cardiomyocyte death in doxorubicin-induced cardiotoxicity
-
Zhang, Y.W. et al. (2009) Cardiomyocyte death in doxorubicin-induced cardiotoxicity. Arch. Immunol. Ther. Exp. (Warsz) 57, 435-445
-
(2009)
Arch. Immunol. Ther. Exp. (Warsz)
, vol.57
, pp. 435-445
-
-
Zhang, Y.W.1
-
52
-
-
61449164929
-
Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model
-
Hydock, D.S. et al. (2009) Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model. J. Cardiovasc. Pharmacol. Ther. 14, 59-67
-
(2009)
J. Cardiovasc. Pharmacol. Ther.
, vol.14
, pp. 59-67
-
-
Hydock, D.S.1
-
53
-
-
78650716667
-
Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury
-
Mukhopadhyay, P. et al. (2011) Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury. Free Radic. Biol. Med. 50, 179-195
-
(2011)
Free Radic. Biol. Med.
, vol.50
, pp. 179-195
-
-
Mukhopadhyay, P.1
-
54
-
-
76749118468
-
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes
-
Mukhopadhyay, P. et al. (2010) CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. Cardiovasc. Res. 85, 773-784
-
(2010)
Cardiovasc. Res.
, vol.85
, pp. 773-784
-
-
Mukhopadhyay, P.1
-
55
-
-
84861454735
-
Cardiac dysfunction in cirrhosis - Does adrenal function play a role? A hypothesis
-
DOI: 10.1111/j.1478-3231.2011.02751.x
-
Theocharidou, E. et al. (2012) Cardiac dysfunction in cirrhosis - does adrenal function play a role? A hypothesis. Liver Int. DOI: 10.1111/j.1478-3231. 2011.02751.x
-
(2012)
Liver Int.
-
-
Theocharidou, E.1
-
56
-
-
0034928628
-
Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
-
Bá tkai, S. et al. (2001) Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat. Med. 7, 827-832
-
(2001)
Nat. Med.
, vol.7
, pp. 827-832
-
-
Bátkai, S.1
-
57
-
-
34548444632
-
Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats
-
Bá tkai, S. et al. (2007) Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. Am. J. Physiol. Heart Circ. Physiol. 293, H1689-H1695
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.293
-
-
Bátkai, S.1
-
58
-
-
27144518128
-
Cirrhotic cardiomyopathy: An endocannabinoid connection?
-
DOI 10.1038/sj.bjp.0706332, PII 0706332
-
Pacher, P. et al. (2005) Cirrhotic cardiomyopathy: an endocannabinoid connection? Br. J. Pharmacol. 146, 313-314 (Pubitemid 41486672)
-
(2005)
British Journal of Pharmacology
, vol.146
, Issue.3
, pp. 313-314
-
-
Pacher, P.1
Batkai, S.2
Kunos, G.3
-
59
-
-
77955305508
-
Mechanisms of TNFalpha-induced cardiac dysfunction in cholestatic bile duct-ligated mice: Interaction between TNFalpha and endocannabinoids
-
Yang, Y.Y. et al. (2010) Mechanisms of TNFalpha-induced cardiac dysfunction in cholestatic bile duct-ligated mice: interaction between TNFalpha and endocannabinoids. J. Hepatol. 53, 298-306
-
(2010)
J. Hepatol.
, vol.53
, pp. 298-306
-
-
Yang, Y.Y.1
-
60
-
-
34447318605
-
Quantitative ultrasonic tissue characterization as a new tool for continuous monitoring of chronic liver remodelling in mice
-
DOI 10.1111/j.1478-3231.2007.01493.x
-
Guimond, A. et al. (2007) Quantitative ultrasonic tissue characterization as a new tool for continuous monitoring of chronic liver remodelling in mice. Liver Int. 27, 854-864 (Pubitemid 47062053)
-
(2007)
Liver International
, vol.27
, Issue.6
, pp. 854-864
-
-
Guimond, A.1
Teletin, M.2
Garo, E.3
D'Sa, A.4
Selloum, M.5
Champy, M.-F.6
Vonesch, J.-L.7
Monassier, L.8
-
61
-
-
33845186019
-
1 receptors
-
DOI 10.1038/sj.bjp.0706928, PII 0706928
-
Moezi, L. et al. (2006) Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB1 and VR1 receptors. Br. J. Pharmacol. 149, 898-908 (Pubitemid 44851714)
-
(2006)
British Journal of Pharmacology
, vol.149
, Issue.7
, pp. 898-908
-
-
Moezi, L.1
Gaskari, S.A.2
Liu, H.3
Baik, S.K.4
Dehpour, A.R.5
Lee, S.S.6
-
62
-
-
32644441249
-
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients - RIO-North America: A randomized controlled trial
-
DOI 10.1001/jama.295.7.761
-
Pi-Sunyer, F.X. et al. (2006) Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. J. Am. Med. Assoc. 295, 761-775 (Pubitemid 43244304)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.7
, pp. 761-775
-
-
Pi-Sunyer, F.X.1
Aronne, L.J.2
Heshmati, H.M.3
Devin, J.4
Rosenstock, J.5
-
63
-
-
17144382751
-
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-Year experience from the RIO-Europe study
-
DOI 10.1016/S0140-6736(05)66374-X
-
Van Gaal, L.F. et al. (2005) Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365, 1389-1397 (Pubitemid 40523733)
-
(2005)
Lancet
, vol.365
, Issue.9468
, pp. 1389-1397
-
-
Van Gaal, L.F.1
Rissanen, A.M.2
Scheen, A.J.3
Ziegler, O.4
Rossner, S.5
-
64
-
-
41649090426
-
Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: The STRADIVARIUS randomized controlled trial
-
DOI 10.1001/jama.299.13.1547
-
Nissen, S.E. et al. (2008) Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial. J. Am. Med. Assoc. 299, 1547-1560 (Pubitemid 351482794)
-
(2008)
JAMA - Journal of the American Medical Association
, vol.299
, Issue.13
, pp. 1547-1560
-
-
Nissen, S.E.1
Nicholls, S.J.2
Wolski, K.3
Rodes-Cabau, J.4
Cannon, C.P.5
Deanfield, J.E.6
Despres, J.-P.7
Kastelein, J.J.P.8
Steinhubl, S.R.9
Kapadia, S.10
Yasin, M.11
Ruzyllo, W.12
Gaudin, C.13
Job, B.14
Hu, B.15
Bhatt, D.L.16
Lincoff, A.M.17
Tuzcu, E.M.18
-
65
-
-
70350347327
-
CB1 antagonists for obesity - What lessons have we learned from rimonabant?
-
Di Marzo, V. and Després, J.P. (2009) CB1 antagonists for obesity - what lessons have we learned from rimonabant? Nat. Rev. Endocrinol. 5, 633-638
-
(2009)
Nat. Rev. Endocrinol.
, vol.5
, pp. 633-638
-
-
Di Marzo, V.1
Després, J.P.2
-
66
-
-
80052035103
-
Energy balance regulation by endocannabinoids at central and peripheral levels
-
Quarta, C. et al. (2011) Energy balance regulation by endocannabinoids at central and peripheral levels. Trends Mol. Med. 17, 518-526
-
(2011)
Trends Mol. Med.
, vol.17
, pp. 518-526
-
-
Quarta, C.1
-
67
-
-
79955632246
-
Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
-
Di Marzo, V. et al. (2011) Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes. Handb. Exp. Pharmacol. 203, 75-104
-
(2011)
Handb. Exp. Pharmacol.
, vol.203
, pp. 75-104
-
-
Di Marzo, V.1
-
68
-
-
67449165616
-
Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis
-
Montecucco, F. et al. (2009) Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis. Atherosclerosis 205, 433-441
-
(2009)
Atherosclerosis
, vol.205
, pp. 433-441
-
-
Montecucco, F.1
-
69
-
-
58849099529
-
Rimonabant, a selective cannabinoid CB1 receptor antagonist, inhibits atherosclerosis in LDL receptor-deficient mice
-
Dol-Gleizes, F. et al. (2009) Rimonabant, a selective cannabinoid CB1 receptor antagonist, inhibits atherosclerosis in LDL receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 29, 12-18
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 12-18
-
-
Dol-Gleizes, F.1
-
70
-
-
77953099666
-
CB1 receptor inhibition leads to decreased vascular AT1 receptor expression, inhibition of oxidative stress and improved endothelial function
-
Tiyerili, V. et al. (2010) CB1 receptor inhibition leads to decreased vascular AT1 receptor expression, inhibition of oxidative stress and improved endothelial function. Basic Res. Cardiol. 105, 465-477
-
(2010)
Basic Res. Cardiol.
, vol.105
, pp. 465-477
-
-
Tiyerili, V.1
-
71
-
-
58149471799
-
Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: Associations with changes in metabolic risk factors
-
Di Marzo, V. et al. (2009) Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. Diabetologia 52, 213-217
-
(2009)
Diabetologia
, vol.52
, pp. 213-217
-
-
Di Marzo, V.1
-
72
-
-
79958109354
-
Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity
-
Quercioli, A. et al. (2011) Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. Eur. Heart J. 32, 1369-1378
-
(2011)
Eur. Heart J.
, vol.32
, pp. 1369-1378
-
-
Quercioli, A.1
-
73
-
-
59049102067
-
Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid 1 receptor blockade on macrophages
-
Sugamura, K. et al. (2009) Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid 1 receptor blockade on macrophages. Circulation 119, 28-36
-
(2009)
Circulation
, vol.119
, pp. 28-36
-
-
Sugamura, K.1
-
74
-
-
0034653517
-
Functional CB1 cannabinoid receptors in human vascular endothelial cells
-
DOI 10.1042/0264-6021:3460835
-
Liu, J. et al. (2000) Functional CB1 cannabinoid receptors in human vascular endothelial cells. Biochem. J. 346, 835-840 (Pubitemid 30171048)
-
(2000)
Biochemical Journal
, vol.346
, Issue.3
, pp. 835-840
-
-
Liu, J.1
Gao, B.2
Mirshahi, F.3
Sanyal, A.J.4
Khanolkar, A.D.5
Makriyannis, A.6
Kunos, G.7
-
75
-
-
77952604846
-
Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells
-
Rajesh, M. et al. (2010) Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells. Br. J. Pharmacol. 160, 688-700
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 688-700
-
-
Rajesh, M.1
-
76
-
-
70849114191
-
CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages
-
Han, K.H. et al. (2009) CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages. Cardiovasc. Res. 84, 378-386
-
(2009)
Cardiovasc. Res.
, vol.84
, pp. 378-386
-
-
Han, K.H.1
-
77
-
-
56349095425
-
Cannabinoid CB1 receptor inhibition decreases vascular smooth muscle migration and proliferation
-
Rajesh, M. et al. (2008) Cannabinoid CB1 receptor inhibition decreases vascular smooth muscle migration and proliferation. Biochem. Biophys. Res. Commun. 377, 1248-1252
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 1248-1252
-
-
Rajesh, M.1
-
78
-
-
79957784091
-
Mechanisms of smooth muscle cell proliferation and endothelial regeneration after vascular injury and stenting: Approach to therapy
-
Curcio, A. et al. (2011) Mechanisms of smooth muscle cell proliferation and endothelial regeneration after vascular injury and stenting: approach to therapy. Circ. J. 75, 1287-1296
-
(2011)
Circ. J.
, vol.75
, pp. 1287-1296
-
-
Curcio, A.1
-
79
-
-
80052547791
-
Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line
-
El-Remessy, A.B. et al. (2011) Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line. Diabetologia 54, 1567-1578
-
(2011)
Diabetologia
, vol.54
, pp. 1567-1578
-
-
El-Remessy, A.B.1
-
80
-
-
84863116202
-
Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy
-
Rajesh, M. et al. (2012) Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. Diabetes 61, 716-727
-
(2012)
Diabetes
, vol.61
, pp. 716-727
-
-
Rajesh, M.1
-
81
-
-
84856010479
-
The endocannabinoid system and plantderived cannabinoids in diabetes and diabetic complications
-
Horvá th, B. et al. (2012) The endocannabinoid system and plantderived cannabinoids in diabetes and diabetic complications. Am. J. Pathol. 180, 432-442
-
(2012)
Am. J. Pathol.
, vol.180
, pp. 432-442
-
-
Horváth, B.1
-
82
-
-
67149122049
-
Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction
-
Maeda, N. et al. (2009) Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. Fundam. Clin. Pharmacol. 23, 351-357
-
(2009)
Fundam. Clin. Pharmacol.
, vol.23
, pp. 351-357
-
-
Maeda, N.1
-
84
-
-
35348946336
-
2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion
-
DOI 10.1152/ajpheart.00688.2007
-
Rajesh, M. et al. (2007) CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. Am. J. Physiol. Heart Circ. Physiol. 293, H2210-H2218 (Pubitemid 47605864)
-
(2007)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.293
, Issue.4
-
-
Rajesh, M.1
Mukhopadhyay, P.2
Batkai, S.3
Hasko, G.4
Liaudet, L.5
Huffman, J.W.6
Csiszar, A.7
Ungvari, Z.8
Mackie, K.9
Chatterjee, S.10
Pacher, P.11
-
85
-
-
80055107075
-
Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo
-
Hoyer, F.F. et al. (2011) Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo. J. Mol. Cell Cardiol. 51, 1007-1014
-
(2011)
J. Mol. Cell Cardiol.
, vol.51
, pp. 1007-1014
-
-
Hoyer, F.F.1
-
86
-
-
17144400758
-
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
-
DOI 10.1038/nature03389
-
Steffens, S. et al. (2005) Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice. Nature 434, 782-786 (Pubitemid 44739523)
-
(2005)
Nature
, vol.434
, Issue.7034
, pp. 782-786
-
-
Steffens, S.1
Veillard, N.R.2
Arnaud, C.3
Pelli, G.4
Burger, F.5
Staub, C.6
Zimmer, A.7
Frossard, J.-L.8
Mach, F.9
-
87
-
-
77958495412
-
Cannabinoid receptor type 2 (CB2) deficiency alters atherosclerotic lesion formation in hyperlipidemic Ldlr-null mice
-
Netherland, C.D. et al. (2010) Cannabinoid receptor type 2 (CB2) deficiency alters atherosclerotic lesion formation in hyperlipidemic Ldlr-null mice. Atherosclerosis 213, 102-108
-
(2010)
Atherosclerosis
, vol.213
, pp. 102-108
-
-
Netherland, C.D.1
-
88
-
-
80053487797
-
Cannabinoid receptor 2 deficiency in haematopoietic cells aggravates early atherosclerosis in LDL receptor deficient mice
-
Delsing, D.J. et al. (2011) Cannabinoid receptor 2 deficiency in haematopoietic cells aggravates early atherosclerosis in LDL receptor deficient mice. Open Cardiovasc. Med. J. 5, 15-21
-
(2011)
Open Cardiovasc. Med. J.
, vol.5
, pp. 15-21
-
-
Delsing, D.J.1
-
89
-
-
38349113185
-
CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration
-
Rajesh, M. et al. (2008) CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration. Br. J. Pharmacol. 153, 347-357
-
(2008)
Br. J. Pharmacol.
, vol.153
, pp. 347-357
-
-
Rajesh, M.1
-
90
-
-
84857346670
-
The cannabinoid receptor CB2 protects against balloon-induced neointima formation
-
Molica, F. et al. (2012) The cannabinoid receptor CB2 protects against balloon-induced neointima formation. Am. J. Physiol. Heart Circ. Physiol. 312, H1064-H1074
-
(2012)
Am. J. Physiol. Heart Circ. Physiol.
, vol.312
-
-
Molica, F.1
-
91
-
-
84859496535
-
The activation of the cannabinoid receptor type 2 (CB2) reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques
-
DOI: 10.1093/eurheartj/ehr449
-
Montecucco, F. et al. (2011) The activation of the cannabinoid receptor type 2 (CB2) reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques. Eur. Heart J. DOI: 10.1093/eurheartj/ehr449
-
(2011)
Eur. Heart J.
-
-
Montecucco, F.1
|