Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells

Biochemical Journal

Volumn 358, Issue 1, 2001, Pages 249-255

  Di Marzo, V ^a   Melck, D ^a   Orlando, P ^a   Bisogno, T ^a   Zagoory, O ^a   Bifulco, M ^a   Vogel, Z ^a   De Petrocellis, L ^a  

^a Istituto per la Chimica di Molecole di Interesse Biologico   (Italy)

Author keywords

2 Arachidonoylglycerol; Arvanil; Cell proliferation; Endocannabinoids; Receptors

Indexed keywords

ENZYMES; FATTY ACIDS; PHARMACODYNAMICS; TUMORS;

HUMAN BREAST CANCER CELLS (HBCCS);

BIOCHEMISTRY;

5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; ADENYLATE CYCLASE; ANANDAMIDE; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; CYTOSTATIC AGENT; DEXANABINOL; FATTY ACID AMIDASE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN 3 RECEPTOR; PALMIDROL;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMIDOHYDROLASES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; ARACHIDONIC ACIDS; BLOTTING, WESTERN; BORNANES; BREAST NEOPLASMS; CANNABINOIDS; CAPSAICIN; CELL DIVISION; COS CELLS; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCANNABINOIDS; FORSKOLIN; GLYCERIDES; HUMANS; HYDROLYSIS; INHIBITORY CONCENTRATION 50; PALMITIC ACIDS; POLYUNSATURATED ALKAMIDES; PROTEIN BINDING; PYRAZOLES; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035881542     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3580249     Document Type: Article

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