메뉴 건너뛰기




Volumn 293, Issue 6, 2007, Pages

Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury

Author keywords

Cannabinoids; Ischemia reperfusion; Myocardial infarction; Pharmacotherapy

Indexed keywords

CANNABIDIOL; INTERLEUKIN 6;

EID: 36849091565     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00098.2007     Document Type: Article
Times cited : (100)

References (38)
  • 2
    • 29844435136 scopus 로고    scopus 로고
    • Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
    • Blake DR, Robson P, Ho M, Jubb RW, McCabe CS. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology 45: 50-52, 2006.
    • (2006) Rheumatology , vol.45 , pp. 50-52
    • Blake, D.R.1    Robson, P.2    Ho, M.3    Jubb, R.W.4    McCabe, C.S.5
  • 3
    • 0037424211 scopus 로고    scopus 로고
    • Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart
    • Bouchard JF, Lepicier P, Lamontagne D. Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart. Life Sci 72: 1859-1870, 2003.
    • (2003) Life Sci , vol.72 , pp. 1859-1870
    • Bouchard, J.F.1    Lepicier, P.2    Lamontagne, D.3
  • 4
    • 4344585483 scopus 로고    scopus 로고
    • An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis
    • Brady CM, DasGupta R, Dalton C, Wiseman OJ, Berkley KJ, Fowler CJ. An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. Mult Scler 10: 425-433, 2004.
    • (2004) Mult Scler , vol.10 , pp. 425-433
    • Brady, C.M.1    DasGupta, R.2    Dalton, C.3    Wiseman, O.J.4    Berkley, K.J.5    Fowler, C.J.6
  • 5
    • 33646734889 scopus 로고    scopus 로고
    • Inhibition of an equilibrative nucleoside transporter by cannabidiol: A mechanism of cannabinoid immunosuppression
    • Carrier EJ, Auchampach JA, Hillard CJ. Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. Proc Natl Acad Sci USA 103: 7895-7900, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7895-7900
    • Carrier, E.J.1    Auchampach, J.A.2    Hillard, C.J.3
  • 6
    • 23044486763 scopus 로고    scopus 로고
    • Cannabinoids and the immune system: Potential for the treatment of inflammatory diseases?
    • Croxford JL, Yamamura T. Cannabinoids and the immune system: potential for the treatment of inflammatory diseases? J Neuroimmunol 166: 3-18, 2005.
    • (2005) J Neuroimmunol , vol.166 , pp. 3-18
    • Croxford, J.L.1    Yamamura, T.2
  • 9
    • 0015221354 scopus 로고
    • The isolation and structure of delta-1-tetrahydrocannabinol and other neutral cannabinoids from hashish
    • Gaoni Y, Mechoulam R. The isolation and structure of delta-1-tetrahydrocannabinol and other neutral cannabinoids from hashish. J Am Chem Soc 93: 217-224, 1971.
    • (1971) J Am Chem Soc , vol.93 , pp. 217-224
    • Gaoni, Y.1    Mechoulam, R.2
  • 10
    • 0037406233 scopus 로고    scopus 로고
    • Meta-analysis of corticosteroid treatment in acute myocardial infarction
    • Giugliano GR, Giugliano RP, Gibson CM, Kuntz RE. Meta-analysis of corticosteroid treatment in acute myocardial infarction. Am J Cardiol 91: 1055-1059, 2003.
    • (2003) Am J Cardiol , vol.91 , pp. 1055-1059
    • Giugliano, G.R.1    Giugliano, R.P.2    Gibson, C.M.3    Kuntz, R.E.4
  • 11
    • 19444363878 scopus 로고    scopus 로고
    • 3 adenosine receptor-mediated protection of the ischemic heart. Pharmacological preconditioning: Potential new treatment modalities for the ischemic myocardium
    • 3 adenosine receptor-mediated protection of the ischemic heart. Pharmacological preconditioning: potential new treatment modalities for the ischemic myocardium. Vasc Pharmacol 42: 271-279, 2005.
    • (2005) Vasc Pharmacol , vol.42 , pp. 271-279
    • Headrick, J.P.1    Peart, J.2
  • 12
    • 33644770260 scopus 로고    scopus 로고
    • Adenosine receptors as therapeutic targets
    • Jacobson KA, Gao ZG. Adenosine receptors as therapeutic targets. Nat Rev Drug Discov 5: 247-264, 2006.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 247-264
    • Jacobson, K.A.1    Gao, Z.G.2
  • 13
    • 0036023638 scopus 로고    scopus 로고
    • Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts
    • Joyeux M, Arnaud C, Godin-Ribuot D, Demenge P, Lamontagne D, Ribuot C. Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts. Cardiovasc Res 55: 619-625, 2002.
    • (2002) Cardiovasc Res , vol.55 , pp. 619-625
    • Joyeux, M.1    Arnaud, C.2    Godin-Ribuot, D.3    Demenge, P.4    Lamontagne, D.5    Ribuot, C.6
  • 14
    • 33746736963 scopus 로고    scopus 로고
    • Limiting myocardial damage during acute myocardial infarction by inhibiting C-reactive protein
    • Kitsis RN, Jialal I. Limiting myocardial damage during acute myocardial infarction by inhibiting C-reactive protein. N Engl J Med 355: 513-515, 2006.
    • (2006) N Engl J Med , vol.355 , pp. 513-515
    • Kitsis, R.N.1    Jialal, I.2
  • 18
    • 0037207079 scopus 로고    scopus 로고
    • Cannabidiol: An overview of some chemical and pharmacological aspects. I. Chemical aspects
    • Mechoulam R, Hanus L. Cannabidiol: an overview of some chemical and pharmacological aspects. I. Chemical aspects. Chem Phys Lipids 121: 35-43, 2002.
    • (2002) Chem Phys Lipids , vol.121 , pp. 35-43
    • Mechoulam, R.1    Hanus, L.2
  • 19
    • 0033027778 scopus 로고    scopus 로고
    • Heat acclimation induces changes in cardiac mechanical performance: The role of thyroid hormone
    • Mirit E, Palmon A, Hasin Y, Horowitz M. Heat acclimation induces changes in cardiac mechanical performance: the role of thyroid hormone. Am J Physiol Regul Integr Comp Physiol 276: R550-R558, 1999.
    • (1999) Am J Physiol Regul Integr Comp Physiol , vol.276
    • Mirit, E.1    Palmon, A.2    Hasin, Y.3    Horowitz, M.4
  • 20
    • 36849089887 scopus 로고
    • A method for the quantitation of myocardial infarcts and the relation of serum enzyme levels to infarct size
    • Nachlas MM, Friedman MM, Cohen SP. A method for the quantitation of myocardial infarcts and the relation of serum enzyme levels to infarct size. Surgery 55: 700-708, 1964.
    • (1964) Surgery , vol.55 , pp. 700-708
    • Nachlas, M.M.1    Friedman, M.M.2    Cohen, S.P.3
  • 21
    • 0001120360 scopus 로고
    • Macroscopic identification of early myocardial infarcts by alterations in dehydrogenase activity
    • Nachlas MM, Shnitka TK. Macroscopic identification of early myocardial infarcts by alterations in dehydrogenase activity. Am J Pathol 42: 379-405, 1963.
    • (1963) Am J Pathol , vol.42 , pp. 379-405
    • Nachlas, M.M.1    Shnitka, T.K.2
  • 24
    • 84884474728 scopus 로고    scopus 로고
    • Pharmacological actions of cannabinoids
    • New York: Springer
    • Pertwee RG. Pharmacological actions of cannabinoids. In: Handbook of Experimental Pharmacology. New York: Springer, 2005, p. 1-51.
    • (2005) Handbook of Experimental Pharmacology , pp. 1-51
    • Pertwee, R.G.1
  • 26
    • 25444530723 scopus 로고    scopus 로고
    • Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis
    • Rog DJ, Nurmikko TJ, Friede T, Young CA. Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology 65: 812-819, 2005.
    • (2005) Neurology , vol.65 , pp. 812-819
    • Rog, D.J.1    Nurmikko, T.J.2    Friede, T.3    Young, C.A.4
  • 30
    • 0023394373 scopus 로고
    • Effects of methylprednisolone on collagen biosynthesis in healing acute myocardial infarction
    • Vivaldi MT, Eyre DR, Kloner RA, Schoen FJ. Effects of methylprednisolone on collagen biosynthesis in healing acute myocardial infarction. Am J Cardiol 60: 424-425, 1987.
    • (1987) Am J Cardiol , vol.60 , pp. 424-425
    • Vivaldi, M.T.1    Eyre, D.R.2    Kloner, R.A.3    Schoen, F.J.4
  • 31
    • 0038753984 scopus 로고    scopus 로고
    • 1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction
    • 1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction. Br J Pharmacol 138: 1251-1258, 2003.
    • (2003) Br J Pharmacol , vol.138 , pp. 1251-1258
    • Wagner, J.A.1    Hu, K.2    Karcher, J.3    Bauersachs, J.4    Schafer, A.5    Laser, M.6    Han, H.7    Ertl, G.8
  • 38
    • 0242654882 scopus 로고    scopus 로고
    • Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): Multicentre randomised placebo-controlled trial
    • Zajicek J, Fox P, Sanders H, Wright D, Vickery J, Nunn A, Thompson A. Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial. Lancet 362: 1517-1526, 2003.
    • (2003) Lancet , vol.362 , pp. 1517-1526
    • Zajicek, J.1    Fox, P.2    Sanders, H.3    Wright, D.4    Vickery, J.5    Nunn, A.6    Thompson, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.