Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrPC-deficiency

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 23, 2012, Pages 9035-9040

  Daude, Nathalie ^a   Wohlgemuth, Serene ^a   Brown, Rebecca ^b   Pitstick, Rose ^b   Gapeshina, Hristina ^a   Yang, Jing ^a   Carlson, George A ^b   Westaway, David ^a,c  

^a UNIVERSITY OF ALBERTA   (Canada)

^b McLaughin Research Institute   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Disease susceptibility; Genetic redundancy; Prion gene family

Indexed keywords

GLYCOPROTEIN; MTG1 PROTEIN; NEUROPEPTIDE; PRION PROTEIN; PROTEIN; SHADOO NEUROPEPTIDE; SPRN PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ALLELE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FRACTIONATION; CONTROLLED STUDY; CYTOLOGY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE SEQUENCE; GENETIC TRANSCRIPTION; HOMOZYGOSITY; INCUBATION TIME; LETHALITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; CELL FRACTIONATION; CELL SURVIVAL; CROSSES, GENETIC; EMBRYONIC DEVELOPMENT; FETAL VIABILITY; GENETIC VECTORS; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; NEUROPEPTIDES; PRPC PROTEINS;

MUS;

EID: 84861863695     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1202130109     Document Type: Article

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