A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers

Journal of Clinical Investigation

Volumn 122, Issue 6, 2012, Pages 2018-2031

  LaBelle, James L ^a,b,c   Katz, Samuel G ^a,c,d   Bird, Gregory H ^a,c   Gavathiotis, Evripidis ^a,c   Stewart, Michelle L ^a   Lawrence, Chelsea ^a   Fisher, Jill K ^a   Godes, Marina ^a   Pitter, Kenneth ^a   Kung, Andrew L ^a,b,c   Walensky, Loren D ^a,b,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BH3 PROTEIN; BIM PROTEIN; BIM STABILIZED ALPHA HELIX OF BCL 2 DOMAIN; HYDROCARBON; NAVITOCLAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ALPHA HELIX; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING AFFINITY; BLOOD DISEASE; BONE MARROW; CANCER CELL; CONTROLLED STUDY; DISEASE MODEL; FEMALE; HUMAN; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN MODIFICATION; XENOGRAFT;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; HUMANS; LEUKEMIA, MYELOID, ACUTE; MEMBRANE PROTEINS; MICE; NEOPLASM TRANSPLANTATION; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84861834043     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI46231     Document Type: Article

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