Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 51, 2008, Pages 20327-20332

  Chipuk, Jerry E ^a   Fisher, John C ^a   Dillon, Christopher P ^a   Kriwacki, Richard W ^a,b   Kuwana, Tomomi ^c   Green, Douglas R ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

BCL 2 family; Mitochondria; MOMP; PUMA

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PUMA PROTEIN;

APOPTOSIS; ARTICLE; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; LIFESPAN; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION; MITOCHONDRION; OUTER MEMBRANE; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; MICE; MITOCHONDRIAL MEMBRANES; PERMEABILITY; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 58149511987     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0808036105     Document Type: Article

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