Presymptomatic alterations in energy metabolism and oxidative stress in the APP23 mouse model of Alzheimer disease

Journal of Proteome Research

Volumn 11, Issue 6, 2012, Pages 3295-3304

  Hartl, Daniela ^a   Schuldt, Victoria ^a   Forler, Stephanie ^a   Zabel, Claus ^a   Klose, Joachim ^a   Rohe, Michael ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Abeta; Alzheimer disease; APP23; energy metabolism; mouse model; proteome

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMYLOID; REACTIVE OXYGEN METABOLITE; SYNTAXIN; AMYLOID PRECURSOR PROTEIN; PROTEOME;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CARBONYLATION; CONTROLLED STUDY; ENERGY METABOLISM; HOMEOSTASIS; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; UPREGULATION; ANIMAL; ASYMPTOMATIC DISEASE; C57BL MOUSE; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOLOGY; PHYSIOLOGY; PROTEIN CARBONYLATION; SYNAPSE; TRANSGENIC MOUSE;

MUS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ASYMPTOMATIC DISEASES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; OXIDATIVE STRESS; PROTEIN CARBONYLATION; PROTEOME; SYNAPSES;

EID: 84861793201     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300021e     Document Type: Article

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