메뉴 건너뛰기




Volumn 26, Issue 7, 2006, Pages 865-877

Neuronal-glial glucose oxidation and glutamatergic-GABAergic function

Author keywords

Baseline; fMRI; Neuroimaging; Oxygen; Perfusion; Signaling

Indexed keywords

4 AMINOBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; CARBON 13; CARBON 14; GLUCOSE; GLUTAMIC ACID; LACTIC ACID; NEUROTRANSMITTER; PYRUVIC ACID; SODIUM ION;

EID: 33745556489     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600263     Document Type: Review
Times cited : (347)

References (117)
  • 1
    • 0035933660 scopus 로고    scopus 로고
    • Temporal dynamics of the partial pressure of brain tissue oxygen during functional forepaw stimulation in rats
    • Ances BM, Buerk DG, Greenberg JH, Detre JA (2001) Temporal dynamics of the partial pressure of brain tissue oxygen during functional forepaw stimulation in rats. Neurosci Lett 306:106-10
    • (2001) Neurosci Lett , vol.306 , pp. 106-110
    • Ances, B.M.1    Buerk, D.G.2    Greenberg, J.H.3    Detre, J.A.4
  • 2
    • 0036889792 scopus 로고    scopus 로고
    • The neural basis of functional brain imaging signals
    • Attwell D, Iadecola C (2002) The neural basis of functional brain imaging signals. Trends Neurosci 25:621-5
    • (2002) Trends Neurosci , vol.25 , pp. 621-625
    • Attwell, D.1    Iadecola, C.2
  • 3
    • 0021985294 scopus 로고
    • A laminar analysis of the number of round-asymmetrical and flat-symmetrical synapses on spines, dendritic trunks, and cell bodies in area 17 of the cat
    • Beaulieu C, Colonnier M (1985) A laminar analysis of the number of round-asymmetrical and flat-symmetrical synapses on spines, dendritic trunks, and cell bodies in area 17 of the cat. J Comp Neurol 231:180-9
    • (1985) J Comp Neurol , vol.231 , pp. 180-189
    • Beaulieu, C.1    Colonnier, M.2
  • 4
    • 0016746875 scopus 로고
    • Metabolism of amino acids and ammonia in rat brain cortex slices in vitro: A possible role of ammonia in brain function
    • Benjamin AM, Quastel JH (1975) Metabolism of amino acids and ammonia in rat brain cortex slices in vitro: a possible role of ammonia in brain function. J Neurochem 25:197-206
    • (1975) J Neurochem , vol.25 , pp. 197-206
    • Benjamin, A.M.1    Quastel, J.H.2
  • 5
    • 73049161747 scopus 로고
    • Metabolic compartments in vivo. Ammonia and glutamic acid metabolism in brain and liver
    • Berl S, Takagaki G, Clarke DD, Waelsch H (1962) Metabolic compartments in vivo. Ammonia and glutamic acid metabolism in brain and liver. J Biol Chem 237:2562-9
    • (1962) J Biol Chem , vol.237 , pp. 2562-2569
    • Berl, S.1    Takagaki, G.2    Clarke, D.D.3    Waelsch, H.4
  • 7
    • 0034002273 scopus 로고    scopus 로고
    • Lactate transporters (MCT proteins) in heart and skeletal muscles
    • Bonen A (2000) Lactate transporters (MCT proteins) in heart and skeletal muscles. Med Sci Sports Exerc 32:778-89
    • (2000) Med Sci Sports Exerc , vol.32 , pp. 778-789
    • Bonen, A.1
  • 8
    • 0036545332 scopus 로고    scopus 로고
    • Lactate shuttles in nature
    • Brooks GA (2002) Lactate shuttles in nature. Biochem Soc Trans 30:258-64
    • (2002) Biochem Soc Trans , vol.30 , pp. 258-264
    • Brooks, G.A.1
  • 9
    • 0142027742 scopus 로고    scopus 로고
    • GABA uptake into astrocytes is not associated with significant metabolic cost: Implications for brain imaging of inhibitory transmission
    • Chatton JY, Pellerin L, Magistretti PJ (2003) GABA uptake into astrocytes is not associated with significant metabolic cost: implications for brain imaging of inhibitory transmission. Proc Natl Acad Sci USA 100:12456-61
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12456-12461
    • Chatton, J.Y.1    Pellerin, L.2    Magistretti, P.J.3
  • 15
    • 0035478762 scopus 로고    scopus 로고
    • Do active cerebral neurons really use lactate rather than glucose?
    • Chih CP, Lipton P, Roberts EL, Jr (2001) Do active cerebral neurons really use lactate rather than glucose? Trends Neurosci 24:573-8
    • (2001) Trends Neurosci , vol.24 , pp. 573-578
    • Chih, C.P.1    Lipton, P.2    Roberts Jr., E.L.3
  • 16
    • 0242574396 scopus 로고    scopus 로고
    • Energy substrates for neurons during neural activity: A critical review of the astrocyte-neuron lactate shuttle hypothesis
    • Chih CP, Roberts EL, Jr (2003) Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis. J Cereb Blood Flow Metab 23:1263-81
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 1263-1281
    • Chih, C.P.1    Roberts Jr., E.L.2
  • 17
    • 0034981078 scopus 로고    scopus 로고
    • In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia
    • Choi IY, Lee SP, Kim SG, Gruetter R (2001) In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia. J Cereb Blood Flow Metab 21:653-63
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 653-663
    • Choi, I.Y.1    Lee, S.P.2    Kim, S.G.3    Gruetter, R.4
  • 18
    • 0036842462 scopus 로고    scopus 로고
    • Effect of deep pentobarbital anesthesia on neurotransmitter metabolism in vivo: On the correlation of total glucose consumption with glutamatergic action
    • Choi IY, Lei H, Gruetter R (2002) Effect of deep pentobarbital anesthesia on neurotransmitter metabolism in vivo: on the correlation of total glucose consumption with glutamatergic action. J Cereb Blood Flow Metab 22:1343-51
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1343-1351
    • Choi, I.Y.1    Lei, H.2    Gruetter, R.3
  • 19
    • 0033822019 scopus 로고    scopus 로고
    • Single-shot, three-dimensional 'non-echo' localization method for in vivo NMR spectroscopy
    • Choi IY, Tkac I, Gruetter R (2000) Single-shot, three-dimensional 'non-echo' localization method for in vivo NMR spectroscopy. Magn Reson Med 44:387-94
    • (2000) Magn Reson Med , vol.44 , pp. 387-394
    • Choi, I.Y.1    Tkac, I.2    Gruetter, R.3
  • 21
    • 0033976985 scopus 로고    scopus 로고
    • Mind glue: Implications of glial cell biology for psychiatry
    • Coyle JT, Schwarcz R (2000) Mind glue: implications of glial cell biology for psychiatry. Arch Gen Psychiatry 57:90-3
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 90-93
    • Coyle, J.T.1    Schwarcz, R.2
  • 22
    • 13644266292 scopus 로고    scopus 로고
    • Activation of astrocytes in brain of conscious rats during acoustic stimulation: Acetate utilization in working brain
    • Cruz NF, Lasater A, Zielke HR, Dienel GA (2005) Activation of astrocytes in brain of conscious rats during acoustic stimulation: acetate utilization in working brain. J Neurochem 92:934-47
    • (2005) J Neurochem , vol.92 , pp. 934-947
    • Cruz, N.F.1    Lasater, A.2    Zielke, H.R.3    Dienel, G.A.4
  • 25
    • 0036319268 scopus 로고    scopus 로고
    • 2 and bicarbonate transporters in metabolic exchanges in the brain
    • 2 and bicarbonate transporters in metabolic exchanges in the brain. J Neurochem 80:721-6
    • (2002) J Neurochem , vol.80 , pp. 721-726
    • Deitmer, J.W.1
  • 26
    • 0029944179 scopus 로고    scopus 로고
    • Kinetics of NMDA channel opening
    • Dzubay JA, Jahr CE (1996) Kinetics of NMDA channel opening. J Neurosci 16:4129-34
    • (1996) J Neurosci , vol.16 , pp. 4129-4134
    • Dzubay, J.A.1    Jahr, C.E.2
  • 27
    • 0023065806 scopus 로고
    • + gradients in cultured glial-derived cell line
    • + gradients in cultured glial-derived cell line. Acta Biochim Pol 34:195-203
    • (1987) Acta Biochim Pol , vol.34 , pp. 195-203
    • Ercinska, M.1    Silver, I.A.2
  • 28
    • 0026061434 scopus 로고
    • Characterization of glutamate uptake systems in astrocyte primary cultures from rat brain
    • Flott B, Seifert W (1991) Characterization of glutamate uptake systems in astrocyte primary cultures from rat brain. Glia 4:293-304
    • (1991) Glia , vol.4 , pp. 293-304
    • Flott, B.1    Seifert, W.2
  • 29
    • 0030021266 scopus 로고    scopus 로고
    • Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man
    • Frahm J, Kruger G, Merboldt KD, Kleinschmidt A (1996) Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man. Magn Reson Med 35:143-8
    • (1996) Magn Reson Med , vol.35 , pp. 143-148
    • Frahm, J.1    Kruger, G.2    Merboldt, K.D.3    Kleinschmidt, A.4
  • 30
    • 0014011060 scopus 로고
    • A simulation study of the metabolism and compartmentation in brain of glutamate, aspartate, the Krebs cycle, and related metabolites
    • Garfinkel D (1966) A simulation study of the metabolism and compartmentation in brain of glutamate, aspartate, the Krebs cycle, and related metabolites. J Biol Chem 241:3918-29
    • (1966) J Biol Chem , vol.241 , pp. 3918-3929
    • Garfinkel, D.1
  • 31
    • 0014966331 scopus 로고
    • A simulation study of brain compartments. I. Fuel sources, and GABA metabolism
    • Garfinkel D (1970) A simulation study of brain compartments. I. Fuel sources, and GABA metabolism. Brain Res 23:387-406
    • (1970) Brain Res , vol.23 , pp. 387-406
    • Garfinkel, D.1
  • 33
    • 0036137183 scopus 로고    scopus 로고
    • Oxidative and nonoxidative metabolism of excited neurons and astrocytes
    • Gjedde A, Marrett S, Vafaee M (2002) Oxidative and nonoxidative metabolism of excited neurons and astrocytes. J Cereb Blood Flow Metab 22:1-14
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1-14
    • Gjedde, A.1    Marrett, S.2    Vafaee, M.3
  • 34
    • 0011512133 scopus 로고    scopus 로고
    • Energy for neurotransmission
    • Griffin JL (1999) Energy for neurotransmission. Science 285:639a
    • (1999) Science , vol.285
    • Griffin, J.L.1
  • 35
    • 0035999512 scopus 로고    scopus 로고
    • 13C NMR studies of compartmentalized cerebral carbohydrate metabolism
    • 13C NMR studies of compartmentalized cerebral carbohydrate metabolism. Neurochem Int 41:143-54
    • (2002) Neurochem Int , vol.41 , pp. 143-154
    • Gruetter, R.1
  • 36
    • 0031595305 scopus 로고    scopus 로고
    • Localized in vivo 13C-NMR of glutamate metabolism in the human brain: Initial results at 4 Tesla
    • Gruetter R, Seaquist ER, Kim S, Ugurbil K (1998) Localized in vivo 13C-NMR of glutamate metabolism in the human brain: initial results at 4 Tesla. Dev Neurosci 20:380-8
    • (1998) Dev Neurosci , vol.20 , pp. 380-388
    • Gruetter, R.1    Seaquist, E.R.2    Kim, S.3    Ugurbil, K.4
  • 37
    • 0034814676 scopus 로고    scopus 로고
    • A mathematical model of compartmentalized neurotransmitter metabolism in the human brain
    • Gruetter R, Seaquist ER, Ugurbil K (2001) A mathematical model of compartmentalized neurotransmitter metabolism in the human brain. Am J Physiol 281:E100-12
    • (2001) Am J Physiol , vol.281
    • Gruetter, R.1    Seaquist, E.R.2    Ugurbil, K.3
  • 38
    • 0028819658 scopus 로고
    • Temporal patterns of uncoupling between oxidative metabolism and regional cerebral blood flow demonstrated by functional magnetic resonance imaging
    • Hedera P, Wu D, Lewin JS, Miller D, Lerner AJ, Friedland RP (1995) Temporal patterns of uncoupling between oxidative metabolism and regional cerebral blood flow demonstrated by functional magnetic resonance imaging. Invest Radiol 30:625-33
    • (1995) Invest Radiol , vol.30 , pp. 625-633
    • Hedera, P.1    Wu, D.2    Lewin, J.S.3    Miller, D.4    Lerner, A.J.5    Friedland, R.P.6
  • 40
    • 0011512133 scopus 로고    scopus 로고
    • Energy for neurotransmission
    • Hertz L, Robinson SR (1999) Energy for neurotransmission. Science 285:639a-639
    • (1999) Science , vol.285
    • Hertz, L.1    Robinson, S.R.2
  • 41
    • 0030931102 scopus 로고    scopus 로고
    • A temporary local energy pool coupled to neuronal activity: Fluctuations of extracellular lactate levels in rat brain monitored with rapid-response enzyme-based sensor
    • Hu Y, Wilson GS (1997) A temporary local energy pool coupled to neuronal activity: fluctuations of extracellular lactate levels in rat brain monitored with rapid-response enzyme-based sensor. J Neurochem 69:1484-90
    • (1997) J Neurochem , vol.69 , pp. 1484-1490
    • Hu, Y.1    Wilson, G.S.2
  • 42
    • 7644230677 scopus 로고    scopus 로고
    • Neuroimaging with calibrated fMRI
    • Hyder F (2004) Neuroimaging with calibrated fMRI. Stroke 35(Suppl 1):2635-41
    • (2004) Stroke , vol.35 , Issue.1 SUPPL. , pp. 2635-2641
    • Hyder, F.1
  • 43
    • 0036678879 scopus 로고    scopus 로고
    • Total neuroenergetics support localized brain activity: Implications for the interpretation of fMRI
    • Hyder F, Rothman DL, Shulman RG (2002) Total neuroenergetics support localized brain activity: implications for the interpretation of fMRI. Proc Natl Acad Sci USA 99:10771-6
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10771-10776
    • Hyder, F.1    Rothman, D.L.2    Shulman, R.G.3
  • 44
    • 4544316033 scopus 로고    scopus 로고
    • Fluorometric determination of glucose utilization in neurons in vitro and in vivo
    • Itoh Y, Abe T, Takaoka R, Tanahashi N (2004) Fluorometric determination of glucose utilization in neurons in vitro and in vivo. J Cereb Blood Flow Metab 24:993-1003
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 993-1003
    • Itoh, Y.1    Abe, T.2    Takaoka, R.3    Tanahashi, N.4
  • 45
    • 0037446874 scopus 로고    scopus 로고
    • Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo
    • Itoh Y, Esaki T, Shimoji K, Cook M, Law MJ, Kaufman E, Sokoloff L (2003) Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo. Proc Natl Acad Sci USA 100:4879-84
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4879-4884
    • Itoh, Y.1    Esaki, T.2    Shimoji, K.3    Cook, M.4    Law, M.J.5    Kaufman, E.6    Sokoloff, L.7
  • 46
    • 0030933001 scopus 로고    scopus 로고
    • Lactate-proton cotransport in skeletal muscle
    • Juel C (1997) Lactate-proton cotransport in skeletal muscle. Physiol Rev 77:321-58
    • (1997) Physiol Rev , vol.77 , pp. 321-358
    • Juel, C.1
  • 47
    • 0028988818 scopus 로고
    • Review: Does measurement of regional cerebral blood flow reflect synaptic activity? Implications for PET and fMRI
    • Jueptner M, Weiller C (1995) Review: does measurement of regional cerebral blood flow reflect synaptic activity? Implications for PET and fMRI. Neuroimage 2:148-56
    • (1995) Neuroimage , vol.2 , pp. 148-156
    • Jueptner, M.1    Weiller, C.2
  • 48
    • 0026595365 scopus 로고
    • Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes
    • Kavanaugh MP, Arriza JL, North RA, Amara SG (1992) Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes. J Biol Chem 267:22007-9
    • (1992) J Biol Chem , vol.267 , pp. 22007-22009
    • Kavanaugh, M.P.1    Arriza, J.L.2    North, R.A.3    Amara, S.G.4
  • 49
    • 8444233570 scopus 로고    scopus 로고
    • The role of hypotheses in current research, illustrated by hypotheses on the possible role of astrocytes in energy metabolism and cerebral blood flow: From Newton to now
    • Kimelberg HK (2004) The role of hypotheses in current research, illustrated by hypotheses on the possible role of astrocytes in energy metabolism and cerebral blood flow: from Newton to now. J Cereb Blood Flow Metab 24:1235-9
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 1235-1239
    • Kimelberg, H.K.1
  • 51
    • 0032928493 scopus 로고    scopus 로고
    • Voltage-gated proton currents in microglia of distinct morphology and functional state
    • Klee R, Heinemann U, Eder C (1999) Voltage-gated proton currents in microglia of distinct morphology and functional state. Neuroscience 91:1415-24
    • (1999) Neuroscience , vol.91 , pp. 1415-1424
    • Klee, R.1    Heinemann, U.2    Eder, C.3
  • 52
    • 0020682119 scopus 로고
    • Amino acids in the substantia nigra of rats with striatal lesions produced by kainic acid
    • Korf J, Venema K (1983) Amino acids in the substantia nigra of rats with striatal lesions produced by kainic acid. J Neurochem 40:1171-3
    • (1983) J Neurochem , vol.40 , pp. 1171-1173
    • Korf, J.1    Venema, K.2
  • 54
    • 0038043143 scopus 로고    scopus 로고
    • Brain function and neurophysiological correlates of signals used in functional neuroimaging
    • Lauritzen M, Gold L (2003) Brain function and neurophysiological correlates of signals used in functional neuroimaging. J Neurosci 23:3972-80
    • (2003) J Neurosci , vol.23 , pp. 3972-3980
    • Lauritzen, M.1    Gold, L.2
  • 57
    • 11844267272 scopus 로고    scopus 로고
    • Neurobarrier coupling in the brain: A partner of neurovascular and neurometabolic coupling?
    • Leybaert L (2005) Neurobarrier coupling in the brain: a partner of neurovascular and neurometabolic coupling? J Cereb Blood Flow Metab 25:2-16
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 2-16
    • Leybaert, L.1
  • 60
    • 0027970863 scopus 로고
    • Glucose transporter proteins in brain
    • Maher F, Vannucci SJ, Simpson IA (1994) Glucose transporter proteins in brain. FASEB J 8:1003-11
    • (1994) FASEB J , vol.8 , pp. 1003-1011
    • Maher, F.1    Vannucci, S.J.2    Simpson, I.A.3
  • 62
  • 63
    • 0028798036 scopus 로고
    • Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutamate/glutamate exchange, and glutamine synthesis in human brain by NMR
    • Mason GF, Gruetter R, Rothman DL, Behar KL, Shulman RG, Novotny EJ (1995) Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutamate/glutamate exchange, and glutamine synthesis in human brain by NMR. J Cereb Blood Flow Metab 15:12-25
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 12-25
    • Mason, G.F.1    Gruetter, R.2    Rothman, D.L.3    Behar, K.L.4    Shulman, R.G.5    Novotny, E.J.6
  • 64
    • 0742305444 scopus 로고    scopus 로고
    • 13C isotopic turnover to determine rates of brain metabolism in vivo
    • 13C isotopic turnover to determine rates of brain metabolism in vivo. Metab Eng 6:75-84
    • (2004) Metab Eng , vol.6 , pp. 75-84
    • Mason, G.F.1    Rothman, D.L.2
  • 66
    • 0024534115 scopus 로고
    • Release of glutamate, aspartate, and gamma-aminobutyric acid from isolated nerve terminals
    • Nicholls DG (1989) Release of glutamate, aspartate, and gamma-aminobutyric acid from isolated nerve terminals. J Neurochem 52:331-41
    • (1989) J Neurochem , vol.52 , pp. 331-341
    • Nicholls, D.G.1
  • 67
    • 0027418419 scopus 로고
    • The glutamatergic nerve terminal
    • Nicholls DG (1993) The glutamatergic nerve terminal. Eur J Biochem 212:613-31
    • (1993) Eur J Biochem , vol.212 , pp. 613-631
    • Nicholls, D.G.1
  • 68
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • Norenberg MD, Martinez-Hernandez A (1979) Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res 161:303-10
    • (1979) Brain Res , vol.161 , pp. 303-310
    • Norenberg, M.D.1    Martinez-Hernandez, A.2
  • 69
    • 0021716227 scopus 로고
    • Glutamate- and GABA-containing neurons in the mouse and rat brain, as demonstrated with a new immunocytochemical technique
    • Ottersen OP, Storm-Mathisen J (1984) Glutamate- and GABA-containing neurons in the mouse and rat brain, as demonstrated with a new immunocytochemical technique. J Comp Neurol 229:374-92
    • (1984) J Comp Neurol , vol.229 , pp. 374-392
    • Ottersen, O.P.1    Storm-Mathisen, J.2
  • 70
    • 0026544324 scopus 로고
    • Metabolic compartmentation of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum
    • Ottersen OP, Zhang N, Walberg F (1992) Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum. Neuroscience 46:519-34
    • (1992) Neuroscience , vol.46 , pp. 519-534
    • Ottersen, O.P.1    Zhang, N.2    Walberg, F.3
  • 77
    • 0016351736 scopus 로고
    • Metabolic compartmentation of glutamate associated with the formation of gamma-aminobutyrate
    • Patel AJ, Johnson AL, Balazs R (1974) Metabolic compartmentation of glutamate associated with the formation of gamma-aminobutyrate. J Neurochem 23:1271-9
    • (1974) J Neurochem , vol.23 , pp. 1271-1279
    • Patel, A.J.1    Johnson, A.L.2    Balazs, R.3
  • 78
    • 0028080101 scopus 로고
    • Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization
    • Pellerin L, Magistretti PJ (1994) Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc Natl Acad Sci USA 91:10625-9
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10625-10629
    • Pellerin, L.1    Magistretti, P.J.2
  • 85
    • 0002587841 scopus 로고
    • Gamma-aminobutyric acid in brain: Its formation from glutamic acid
    • Roberts E, Frankel S (1950) Gamma-aminobutyric acid in brain: its formation from glutamic acid. J Biol Chem 187:55-63
    • (1950) J Biol Chem , vol.187 , pp. 55-63
    • Roberts, E.1    Frankel, S.2
  • 86
    • 0001282691 scopus 로고    scopus 로고
    • In vivo magnetic resonance spectroscopy studies of the glutamate and GABA neurotransmitter cycles and functional neuroenergetics
    • (Davis KL, Charney D, Coyle JT, Nemeroff C, eds), Chapter 25, Philadelphia, PA: Lippincott Williams & Wilkins
    • Rothman DL, Hyder F, Sibson NR, Behar KL, Mason GF, Shen J, Petroff OAC, Shulman RG (2001) In vivo magnetic resonance spectroscopy studies of the glutamate and GABA neurotransmitter cycles and functional neuroenergetics. In: Neuropsychopharmacology: the fifth generation of progress (Davis KL, Charney D, Coyle JT, Nemeroff C, eds), Chapter 25, Philadelphia, PA: Lippincott Williams & Wilkins, 315-42
    • (2001) Neuropsychopharmacology: The Fifth Generation of Progress , pp. 315-342
    • Rothman, D.L.1    Hyder, F.2    Sibson, N.R.3    Behar, K.L.4    Mason, G.F.5    Shen, J.6    Petroff, O.A.C.7    Shulman, R.G.8
  • 87
    • 0033615021 scopus 로고    scopus 로고
    • In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics
    • Rothman DL, Sibson NR, Hyder F, Shen J, Behar KL, Shulman RG (1999) In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics. Philos Trans R Soc London B 354:1165-77
    • (1999) Philos Trans R Soc London B , vol.354 , pp. 1165-1177
    • Rothman, D.L.1    Sibson, N.R.2    Hyder, F.3    Shen, J.4    Behar, K.L.5    Shulman, R.G.6
  • 89
    • 0024224341 scopus 로고
    • Ionic mechanisms of intracellular pH regulation in the nervous system
    • Schlue WR, Deitmer JW (1988) Ionic mechanisms of intracellular pH regulation in the nervous system. Ciba Found Symp 139:47-69
    • (1988) Ciba Found Symp , vol.139 , pp. 47-69
    • Schlue, W.R.1    Deitmer, J.W.2
  • 91
    • 0021988603 scopus 로고
    • Pyruvate carboxylase: An astrocyte-specific enzyme implicated in the replenishment of amino acid neurotransmitter pools
    • Shank RP, Bennett GS, Freytag SO, Campbell GL (1985) Pyruvate carboxylase: an astrocyte-specific enzyme implicated in the replenishment of amino acid neurotransmitter pools. Brain Res 329:364-7
    • (1985) Brain Res , vol.329 , pp. 364-367
    • Shank, R.P.1    Bennett, G.S.2    Freytag, S.O.3    Campbell, G.L.4
  • 93
    • 0035933156 scopus 로고    scopus 로고
    • Cerebral energetics and the glycogen shunt: Neurochemical basis of functional imaging
    • Shulman RG, Hyder F, Rothman DL (2001a) Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging. Proc Natl Acad Sci USA 98:6417-22
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6417-6422
    • Shulman, R.G.1    Hyder, F.2    Rothman, D.L.3
  • 94
    • 0035216574 scopus 로고    scopus 로고
    • Lactate efflux and the neuroenergetic basis of brain function
    • Shulman RG, Hyder F, Rothman DL (2001b) Lactate efflux and the neuroenergetic basis of brain function. NMR Biomed 14:389-96
    • (2001) NMR Biomed , vol.14 , pp. 389-396
    • Shulman, R.G.1    Hyder, F.2    Rothman, D.L.3
  • 95
    • 0036706164 scopus 로고    scopus 로고
    • Biophysical basis of brain activity: Implications for neuroimaging
    • Shulman RG, Hyder F, Rothman DL (2002) Biophysical basis of brain activity: implications for neuroimaging. Q Rev Biophys 35:287-325
    • (2002) Q Rev Biophys , vol.35 , pp. 287-325
    • Shulman, R.G.1    Hyder, F.2    Rothman, D.L.3
  • 96
    • 0032578533 scopus 로고    scopus 로고
    • Interpreting functional imaging studies in terms of neurotransmitter cycling
    • Shulman RG, Rothman DL (1998) Interpreting functional imaging studies in terms of neurotransmitter cycling. Proc Natl Acad Sci USA 95:11993-8
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11993-11998
    • Shulman, R.G.1    Rothman, D.L.2
  • 97
    • 0034744514 scopus 로고    scopus 로고
    • 13C NMR of intermediary metabolism: Implications for systemic physiology
    • 13C NMR of intermediary metabolism: implications for systemic physiology. Annu Rev Physiol 63:15-48
    • (2001) Annu Rev Physiol , vol.63 , pp. 15-48
    • Shulman, R.G.1    Rothman, D.L.2
  • 98
    • 0035895224 scopus 로고    scopus 로고
    • The 'glycogen shunt' in exercising muscle: A role for glycogen in muscle energetics and fatigue
    • Shulman RG, Rothman DL (2001b) The 'glycogen shunt' in exercising muscle: a role for glycogen in muscle energetics and fatigue. Proc Natl Acad Sci USA 98:457-61
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 457-461
    • Shulman, R.G.1    Rothman, D.L.2
  • 99
    • 3242737585 scopus 로고    scopus 로고
    • Energetic basis of brain activity: Implications for neuroimaging
    • Shulman RG, Rothman DL, Behar KL, Hyder F (2004) Energetic basis of brain activity: implications for neuroimaging. Trends Neurosci 27:489-95
    • (2004) Trends Neurosci , vol.27 , pp. 489-495
    • Shulman, R.G.1    Rothman, D.L.2    Behar, K.L.3    Hyder, F.4
  • 104
    • 0032904685 scopus 로고    scopus 로고
    • Energetics of functional activation in neural tissues
    • Sokoloff L (1999) Energetics of functional activation in neural tissues. Neurochem Res 24:321-9
    • (1999) Neurochem Res , vol.24 , pp. 321-329
    • Sokoloff, L.1
  • 105
    • 0018656506 scopus 로고
    • 3H]glutamic acid in excitatory nerve endings: Light and electronmicroscopic observations in the hippocampal formation of the rat
    • 3H]glutamic acid in excitatory nerve endings: light and electronmicroscopic observations in the hippocampal formation of the rat. Neuroscience 4:1237-53
    • (1979) Neuroscience , vol.4 , pp. 1237-1253
    • Storm-Mathisen, J.1    Iversen, L.L.2
  • 107
    • 29144468292 scopus 로고    scopus 로고
    • Regional temperature changes in the brain during somatosensory stimulation
    • Trübel HK, Sacolick LI, Hyder F (2006) Regional temperature changes in the brain during somatosensory stimulation. J Cereb Blood Flow Metab 26:68-78
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 68-78
    • Trübel, H.K.1    Sacolick, L.I.2    Hyder, F.3
  • 108
    • 0029927343 scopus 로고    scopus 로고
    • Metabolic coupling between glia and neurons
    • Tsacopoulos M, Magistretti PJ (1996) Metabolic coupling between glia and neurons. J Neurosci 16:877-85
    • (1996) J Neurosci , vol.16 , pp. 877-885
    • Tsacopoulos, M.1    Magistretti, P.J.2
  • 110
    • 0015071185 scopus 로고
    • A stimulation study of brain compartments. Metabolism of glutamate and related substances in mouse brain
    • Van den Berg CJ, Garfinkel D (1971) A stimulation study of brain compartments. Metabolism of glutamate and related substances in mouse brain. Biochem J 123:211-8
    • (1971) Biochem J , vol.123 , pp. 211-218
    • Van Den Berg, C.J.1    Garfinkel, D.2
  • 111
    • 0014526611 scopus 로고
    • Compartmentation of glutamate metabolism in brain. Evidence for the existence of two different tricarboxylic acid cycles in brain
    • Van den Berg CJ, Krzalic L, Mela P, Waelsch H (1969) Compartmentation of glutamate metabolism in brain. Evidence for the existence of two different tricarboxylic acid cycles in brain. Biochem J 113:281-90
    • (1969) Biochem J , vol.113 , pp. 281-290
    • Van Den Berg, C.J.1    Krzalic, L.2    Mela, P.3    Waelsch, H.4
  • 112
    • 0016719828 scopus 로고
    • The formation of glutamine in mouse brain: Effect of aminooxyacetic acid and ammonia
    • Van den Berg CJ, Matheson DF (1975) The formation of glutamine in mouse brain: effect of aminooxyacetic acid and ammonia. Biochem Soc Trans 3:528-30
    • (1975) Biochem Soc Trans , vol.3 , pp. 528-530
    • Van Den Berg, C.J.1    Matheson, D.F.2
  • 113
    • 0031238676 scopus 로고    scopus 로고
    • Glucose transporter proteins in brain: Delivery of glucose to neurons and glia
    • Vannucci SJ, Maher F, Simpson IA (1997) Glucose transporter proteins in brain: delivery of glucose to neurons and glia. Glia 21:2-21
    • (1997) Glia , vol.21 , pp. 2-21
    • Vannucci, S.J.1    Maher, F.2    Simpson, I.A.3
  • 114
    • 0142084655 scopus 로고    scopus 로고
    • Developmental switch in brain nutrient transporter expression in the rat
    • Vannucci SJ, Simpson IA (2003) Developmental switch in brain nutrient transporter expression in the rat. Am J Physiol 285:E1127-34
    • (2003) Am J Physiol , vol.285
    • Vannucci, S.J.1    Simpson, I.A.2
  • 116
    • 0021037707 scopus 로고
    • Pyruvate carboxylase activity in primary cultures of astrocytes and neurons
    • Yu AC, Drejer J, Hertz L, Schousboe A (1983) Pyruvate carboxylase activity in primary cultures of astrocytes and neurons. J Neurochem 41:1484-7
    • (1983) J Neurochem , vol.41 , pp. 1484-1487
    • Yu, A.C.1    Drejer, J.2    Hertz, L.3    Schousboe, A.4
  • 117
    • 0029860263 scopus 로고    scopus 로고
    • Flux coupling in a neuronal glutamate transporter
    • Zerangue N, Kavanaugh MP (1996) Flux coupling in a neuronal glutamate transporter. Nature 383:634-7
    • (1996) Nature , vol.383 , pp. 634-637
    • Zerangue, N.1    Kavanaugh, M.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.