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Volumn 6, Issue 2, 2012, Pages 134-141

Aggregated proteins in schizophrenia and other chronic mental diseases: DISC1opathies

Author keywords

Aggresomes; Chronic mental diseases; DISC1 pathway; Disrupted in schizophrenia 1 (DISC1); Protein conformational disorder; Protein misassembly; Protein recruitment; Schizophrenia

Indexed keywords

ALPHA SYNUCLEIN; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN;

EID: 84861724500     PISSN: 19336896     EISSN: 1933690X     Source Type: Journal    
DOI: 10.4161/pri.18989     Document Type: Conference Paper
Times cited : (43)

References (93)
  • 2
    • 0034532349 scopus 로고    scopus 로고
    • The epidemiology of onset and course of schizophrenia
    • PMID:11153964
    • an der Heiden W, Häfner H. The epidemiology of onset and course of schizophrenia. Eur Arch Psychiatry Clin Neurosci 2000; 250:292-303; PMID:11153964; http://dx.doi.org/10.1007/s004060070004.
    • (2000) Eur Arch Psychiatry Clin Neurosci , vol.250 , pp. 292-303
    • An Der Heiden, W.1    Häfner, H.2
  • 3
    • 33645226430 scopus 로고    scopus 로고
    • The NIMH-MATRICS consensus statement on negative symptoms
    • PMID:16481659
    • Kirkpatrick B, Fenton WS, Carpenter WT Jr, Marder SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull 2006; 32:214-9; PMID:16481659; http://dx.doi.org/10.1093/schbul/sbj053.
    • (2006) Schizophr Bull , vol.32 , pp. 214-219
    • Kirkpatrick, B.1    Fenton, W.S.2    Carpenter Jr., W.T.3    Marder, S.R.4
  • 4
    • 33845881430 scopus 로고    scopus 로고
    • The Consortium on the Genetics of Schizophrenia: Neurocognitive endophenotypes
    • PMID:17101692
    • Gur RE, Calkins ME, Gur RC, Horan WP, Nuechterlein KH, Seidman LJ, et al. The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes. Schizophr Bull 2007; 33:49-68; PMID:17101692; http://dx.doi.org/10.1093/schbul/ sbl055.
    • (2007) Schizophr Bull , vol.33 , pp. 49-68
    • Gur, R.E.1    Calkins, M.E.2    Gur, R.C.3    Horan, W.P.4    Nuechterlein, K.H.5    Seidman, L.J.6
  • 5
  • 7
    • 77956571921 scopus 로고    scopus 로고
    • Conceptualizing schizophrenia through attenuated symptoms in the population
    • PMID:20826849
    • Carpenter WT Jr. Conceptualizing schizophrenia through attenuated symptoms in the population. Am J Psychiatry 2010; 167:1013-6; PMID:20826849; http://dx.doi.org/10.1176/appi.ajp.2010.10060854.
    • (2010) Am J Psychiatry , vol.167 , pp. 1013-1016
    • Carpenter Jr., W.T.1
  • 8
    • 0035135656 scopus 로고    scopus 로고
    • A separate disease within the syndrome of schizophrenia
    • PMID:11177118
    • Kirkpatrick B, Buchanan RW, Ross DE, Carpenter WT Jr. A separate disease within the syndrome of schizophrenia. Arch Gen Psychiatry 2001; 58:165-71; PMID:11177118; http://dx.doi.org/10.1001/archpsyc.58.2.165.
    • (2001) Arch Gen Psychiatry , vol.58 , pp. 165-171
    • Kirkpatrick, B.1    Buchanan, R.W.2    Ross, D.E.3    Carpenter Jr., W.T.4
  • 9
    • 0004757881 scopus 로고    scopus 로고
    • A Sceptical View of the Neuropathology of Schizophrenia
    • Harrison PJ, Roberts GW, Ed. Oxford: Oxford University Press
    • Chua SE, McKenna PJ. A Sceptical View of the Neuropathology of Schizophrenia. In: Harrison PJ, Roberts GW, Ed. The Neuropathology of Schizophrenia. Oxford: Oxford University Press 2000; 291-337.
    • (2000) The Neuropathology of Schizophrenia , pp. 291-337
    • Chua, S.E.1    McKenna, P.J.2
  • 10
    • 78651204419 scopus 로고
    • Traitement des états d'excitation et d'agitation par une méthode médicamenteuse dérivée de l'hibernothérapie
    • (Paris) PMID:13008201
    • Delay J, Deniker P, Harl JM. Traitement des états d'excitation et d'agitation par une méthode médicamenteuse dérivée de l'hibernothérapie. Ann Med Psychol (Paris) 1952; 110:267-73; PMID:13008201.
    • (1952) Ann Med Psychol , vol.110 , pp. 267-273
    • Delay, J.1    Deniker, P.2    Harl, J.M.3
  • 11
    • 78651116398 scopus 로고
    • Effect of chlorpromazine or haloperidol on the formation of 3-methoxytyramine and norepinephrine in mouse brain
    • (Copenh) PMID:14060771
    • Carlsson A, Lindqvist M. Effect of chlorpromazine or haloperidol on the formation of 3-methoxytyramine and norepinephrine in mouse brain. Acta Pharmacol Toxicol (Copenh) 1963; 20:140-4; PMID:14060771; http://dx.doi.org/10.1111/j. 1600-0773.1963.tb01730.x.
    • (1963) Acta Pharmacol Toxicol , vol.20 , pp. 140-144
    • Carlsson, A.1    Lindqvist, M.2
  • 12
    • 0026070134 scopus 로고
    • Dopamine in schizophrenia: A review and reconceptualization
    • PMID:1681750
    • Davis KL, Kahn RS, Ko G, Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am J Psychiatry 1991; 148:1474-86; PMID:1681750.
    • (1991) Am J Psychiatry , vol.148 , pp. 1474-1486
    • Davis, K.L.1    Kahn, R.S.2    Ko, G.3    Davidson, M.4
  • 13
    • 65349120160 scopus 로고    scopus 로고
    • The dopamine hypothesis of schizophrenia: Version III - The final common pathway
    • PMID:19325164
    • Howes OD, Kapur S. The dopamine hypothesis of schizophrenia: version III - the final common pathway. Schizophr Bull 2009; 35:549-62; PMID:19325164; http://dx.doi.org/10.1093/schbul/sbp006.
    • (2009) Schizophr Bull , vol.35 , pp. 549-562
    • Howes, O.D.1    Kapur, S.2
  • 14
    • 0023215296 scopus 로고
    • Implications of normal brain development for the pathogenesis of schizophrenia
    • PMID:3606332
    • Weinberger DR. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 1987; 44:660-9; PMID:3606332; http://dx.doi.org/10.1001/archpsyc.1987.01800190080012.
    • (1987) Arch Gen Psychiatry , vol.44 , pp. 660-669
    • Weinberger, D.R.1
  • 15
    • 68949178899 scopus 로고    scopus 로고
    • Neurodevelopmental mechanisms of schizophrenia: Understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1
    • PMID:19712980
    • Jaaro-Peled H, Hayashi-Takagi A, Seshadri S, Kamiya A, Brandon NJ, Sawa A. Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1. Trends Neurosci 2009; 32:485-95; PMID:19712980; http://dx.doi.org/10.1016/j.tins.2009.05.007.
    • (2009) Trends Neurosci , vol.32 , pp. 485-495
    • Jaaro-Peled, H.1    Hayashi-Takagi, A.2    Seshadri, S.3    Kamiya, A.4    Brandon, N.J.5    Sawa, A.6
  • 16
    • 0023514436 scopus 로고
    • The significance of genetic factors in the etiology of schizophrenia: Results from the national study of adoptees in Denmark
    • PMID:3440955
    • Kety SS. The significance of genetic factors in the etiology of schizophrenia: results from the national study of adoptees in Denmark. J Psychiatr Res 1987; 21:423-9; PMID:3440955; http://dx.doi.org/10.1016/0022- 3956(87)90089-6.
    • (1987) J Psychiatr Res , vol.21 , pp. 423-429
    • Kety, S.S.1
  • 17
    • 0017027801 scopus 로고
    • A critical review of recent adoption, twin and family studies of schizophrenia: Behavioral genetics perspectives
    • PMID:1034336
    • Gottesman II, Shields J. A critical review of recent adoption, twin and family studies of schizophrenia: behavioral genetics perspectives. Schizophr Bull 1976; 2:360-401; PMID:1034336.
    • (1976) Schizophr Bull , vol.2 , pp. 360-401
    • Gottesman, I.I.1    Shields, J.2
  • 18
    • 0034702026 scopus 로고    scopus 로고
    • Disruption of two novel genes by a translocation co-segregating with schizophrenia
    • PMID:10814723
    • Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, et al. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet 2000; 9:1415-23; PMID:10814723; http://dx.doi.org/10.1093/hmg/9.9.1415.
    • (2000) Hum Mol Genet , vol.9 , pp. 1415-1423
    • Millar, J.K.1    Wilson-Annan, J.C.2    Anderson, S.3    Christie, S.4    Taylor, M.S.5    Semple, C.A.6
  • 20
    • 0037222276 scopus 로고    scopus 로고
    • Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families
    • PMID:12474144
    • Schwab SG, Knapp M, Mondabon S, Hallmayer J, Borrmann-Hassenbach M, Albus M, et al. Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families. Am J Hum Genet 2003; 72:185-90; PMID:12474144; http://dx.doi.org/10.1086/345463.
    • (2003) Am J Hum Genet , vol.72 , pp. 185-190
    • Schwab, S.G.1    Knapp, M.2    Mondabon, S.3    Hallmayer, J.4    Borrmann-Hassenbach, M.5    Albus, M.6
  • 21
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression and neuropathology: On the matter of their convergence
    • PMID:15263907
    • Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression and neuropathology: on the matter of their convergence. Mol Psychiatry 2005; 10:40-68; PMID:15263907; http://dx.doi.org/10.1038/sj.mp.4001558.
    • (2005) Mol Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 22
    • 34547659148 scopus 로고    scopus 로고
    • The genetic deconstruction of psychosis
    • PMID:17551090
    • Owen MJ, Craddock N, Jablensky A. The genetic deconstruction of psychosis. Schizophr Bull 2007; 33:905-11; PMID:17551090; http://dx.doi.org/10. 1093/schbul/sbm053.
    • (2007) Schizophr Bull , vol.33 , pp. 905-911
    • Owen, M.J.1    Craddock, N.2    Jablensky, A.3
  • 23
    • 34347395711 scopus 로고    scopus 로고
    • Rethinking psychosis: The disadvantages of a dichotomous classification now outweigh the advantages
    • PMID:18235858
    • Craddock N, Owen MJ. Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry 2007; 6:84-91; PMID:18235858.
    • (2007) World Psychiatry , vol.6 , pp. 84-91
    • Craddock, N.1    Owen, M.J.2
  • 24
    • 66249116695 scopus 로고    scopus 로고
    • Modeling cognitive endophenotypes of schizophrenia in mice
    • PMID:19409625
    • Kellendonk C, Simpson EH, Kandel ER. Modeling cognitive endophenotypes of schizophrenia in mice. Trends Neurosci 2009; 32:347-58; PMID:19409625; http://dx.doi.org/10.1016/j.tins.2009.02.003.
    • (2009) Trends Neurosci , vol.32 , pp. 347-358
    • Kellendonk, C.1    Simpson, E.H.2    Kandel, E.R.3
  • 25
    • 33749063363 scopus 로고    scopus 로고
    • Modeling madness in mice: One piece at a time
    • PMID:17015235
    • Arguello PA, Gogos JA. Modeling madness in mice: one piece at a time. Neuron 2006; 52:179-96; PMID:17015235; http://dx.doi.org/10.1016/j.neuron.2006. 09.023.
    • (2006) Neuron , vol.52 , pp. 179-196
    • Arguello, P.A.1    Gogos, J.A.2
  • 26
    • 67650410543 scopus 로고    scopus 로고
    • Biological and chemical approaches to diseases of proteostasis deficiency
    • PMID:19298183
    • Powers ET, Morimoto RI, Dillin A, Kelly JW, Balch WE. Biological and chemical approaches to diseases of proteostasis deficiency. Annu Rev Biochem 2009; 78:959-91; PMID:19298183; http://dx.doi.org/10.1146/annurev.biochem. 052308.114844.
    • (2009) Annu Rev Biochem , vol.78 , pp. 959-991
    • Powers, E.T.1    Morimoto, R.I.2    Dillin, A.3    Kelly, J.W.4    Balch, W.E.5
  • 27
    • 0035902194 scopus 로고    scopus 로고
    • Shattuck lecture - Neurodegenerative diseases and prions
    • PMID:11357156
    • Prusiner SB. Shattuck lecture - neurodegenerative diseases and prions. N Engl J Med 2001; 344:1516-26; PMID:11357156; http://dx.doi.org/10.1056/ NEJM200105173442006.
    • (2001) N Engl J Med , vol.344 , pp. 1516-1526
    • Prusiner, S.B.1
  • 28
    • 0037077040 scopus 로고    scopus 로고
    • Toxic proteins in neurodegenerative disease
    • PMID:12065827
    • Taylor JP, Hardy J, Fischbeck KH. Toxic proteins in neurodegenerative disease. Science 2002; 296:1991-5; PMID:12065827; http://dx.doi.org/10.1126/ science.1067122.
    • (2002) Science , vol.296 , pp. 1991-1995
    • Taylor, J.P.1    Hardy, J.2    Fischbeck, K.H.3
  • 30
    • 0026088977 scopus 로고
    • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
    • PMID:1671712
    • Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991; 349:704-6; PMID:1671712; http://dx.doi.org/10.1038/349704a0.
    • (1991) Nature , vol.349 , pp. 704-706
    • Goate, A.1    Chartier-Harlin, M.C.2    Mullan, M.3    Brown, J.4    Crawford, F.5    Fidani, L.6
  • 31
    • 0032568534 scopus 로고    scopus 로고
    • Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
    • PMID:9600990
    • Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc Natl Acad Sci USA 1998; 95:6469-73; PMID:9600990; http://dx.doi.org/10.1073/pnas.95.11.6469.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6469-6473
    • Spillantini, M.G.1    Crowther, R.A.2    Jakes, R.3    Hasegawa, M.4    Goedert, M.5
  • 32
    • 0030744876 scopus 로고    scopus 로고
    • Mutation in the alphasynuclein gene identified in families with Parkinson's disease
    • PMID:9197268
    • Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, et al. Mutation in the alphasynuclein gene identified in families with Parkinson's disease. Science 1997; 276:2045-7; PMID:9197268; http://dx.doi.org/10.1126/ science.276.5321.2045.
    • (1997) Science , vol.276 , pp. 2045-2047
    • Polymeropoulos, M.H.1    Lavedan, C.2    Leroy, E.3    Ide, S.E.4    Dehejia, A.5    Dutra, A.6
  • 33
    • 67650077008 scopus 로고    scopus 로고
    • Transmission and spreading of tauopathy in transgenic mouse brain
    • PMID:19503072
    • Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol 2009; 11:909-13; PMID:19503072; http://dx.doi.org/10.1038/ncb1901.
    • (2009) Nat Cell Biol , vol.11 , pp. 909-913
    • Clavaguera, F.1    Bolmont, T.2    Crowther, R.A.3    Abramowski, D.4    Frank, S.5    Probst, A.6
  • 34
    • 69149089854 scopus 로고    scopus 로고
    • Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
    • PMID:19651612
    • Desplats P, Lee HJ, Bae EJ, Patrick C, Rockenstein E, Crews L, et al. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci USA 2009; 106:13010-5; PMID:19651612; http://dx.doi.org/10.1073/pnas.0903691106.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13010-13015
    • Desplats, P.1    Lee, H.J.2    Bae, E.J.3    Patrick, C.4    Rockenstein, E.5    Crews, L.6
  • 35
    • 59649095699 scopus 로고    scopus 로고
    • Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
    • PMID:19151706
    • Ren PH, Lauckner JE, Kachirskaia I, Heuser JE, Melki R, Kopito RR. Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates. Nat Cell Biol 2009; 11:219-25; PMID:19151706; http://dx.doi.org/10.1038/ncb1830.
    • (2009) Nat Cell Biol , vol.11 , pp. 219-225
    • Ren, P.H.1    Lauckner, J.E.2    Kachirskaia, I.3    Heuser, J.E.4    Melki, R.5    Kopito, R.R.6
  • 36
    • 79952743365 scopus 로고    scopus 로고
    • Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells
    • PMID:21321227
    • Münch C, O'Brien J, Bertolotti A. Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells. Proc Natl Acad Sci USA 2011; 108:3548-53; PMID:21321227; http://dx.doi.org/10.1073/pnas.1017275108.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3548-3553
    • Münch, C.1    O'Brien, J.2    Bertolotti, A.3
  • 37
    • 80053652133 scopus 로고    scopus 로고
    • Intermolecular transmission of superoxide dismutase 1 misfolding in living cells
    • PMID:21930926
    • Grad LI, Guest WC, Yanai A, Pokrishevsky E, O'Neill MA, Gibbs E, et al. Intermolecular transmission of superoxide dismutase 1 misfolding in living cells. Proc Natl Acad Sci USA 2011; 108:16398-403; PMID:21930926; http://dx.doi.org/10.1073/pnas.1102645108.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 16398-16403
    • Grad, L.I.1    Guest, W.C.2    Yanai, A.3    Pokrishevsky, E.4    O'Neill, M.A.5    Gibbs, E.6
  • 38
    • 43249110200 scopus 로고    scopus 로고
    • Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-tograft disease propagation
    • PMID:18391963
    • Li JY, Englund E, Holton JL, Soulet D, Hagell P, Lees AJ, et al. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-tograft disease propagation. Nat Med 2008; 14:501-3; PMID:18391963; http://dx.doi.org/10.1038/nm1746.
    • (2008) Nat Med , vol.14 , pp. 501-503
    • Li, J.Y.1    Englund, E.2    Holton, J.L.3    Soulet, D.4    Hagell, P.5    Lees, A.J.6
  • 39
    • 78649907008 scopus 로고    scopus 로고
    • Cell-to-cell transmission of non-prion protein aggregates
    • PMID:21045796
    • Lee SJ, Desplats P, Sigurdson C, Tsigelny I, Masliah E. Cell-to-cell transmission of non-prion protein aggregates. Nat Rev Neurol 2010; 6:702-6; PMID:21045796; http://dx.doi.org/10.1038/nrneurol.2010.145.
    • (2010) Nat Rev Neurol , vol.6 , pp. 702-706
    • Lee, S.J.1    Desplats, P.2    Sigurdson, C.3    Tsigelny, I.4    Masliah, E.5
  • 40
    • 0025277392 scopus 로고
    • Association within a family of a balanced autosomal translocation with major mental illness
    • PMID:1973210
    • St. Clair D, Blackwood D, Muir W, Carothers A, Walker M, Spowart G, et al. Association within a family of a balanced autosomal translocation with major mental illness. Lancet 1990; 336:13-6; PMID:1973210; http://dx.doi.org/10.1016/ 0140-6736(90)91520-K.
    • (1990) Lancet , vol.336 , pp. 13-16
    • St Clair, D.1    Blackwood, D.2    Muir, W.3    Carothers, A.4    Walker, M.5    Spowart, G.6
  • 41
    • 0034927864 scopus 로고    scopus 로고
    • Schizophrenia and affective disorders - Cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family
    • PMID:11443544
    • Blackwood DH, Fordyce A, Walker MT, St. Clair DM, Porteous DJ, Muir WJ. Schizophrenia and affective disorders - cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am J Hum Genet 2001; 69:428-33; PMID:11443544; http://dx.doi.org/10.1086/321969.
    • (2001) Am J Hum Genet , vol.69 , pp. 428-433
    • Blackwood, D.H.1    Fordyce, A.2    Walker, M.T.3    St Clair, D.M.4    Porteous, D.J.5    Muir, W.J.6
  • 43
    • 28544453286 scopus 로고    scopus 로고
    • A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development
    • PMID:16299498
    • Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, Ozeki Y, et al. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol 2005; 7:1167-78; PMID:16299498; http://dx.doi.org/10.1038/ ncb1328.
    • (2005) Nat Cell Biol , vol.7 , pp. 1167-1178
    • Kamiya, A.1    Kubo, K.2    Tomoda, T.3    Takaki, M.4    Youn, R.5    Ozeki, Y.6
  • 44
    • 38349172768 scopus 로고    scopus 로고
    • Enlargement of the lateral ventricles in mutant DISC1 transgenic mice
    • PMID:18202691
    • Pletnikov MV, Ayhan Y, Xu Y, Nikolskaia O, Ovanesov M, Huang H, et al. Enlargement of the lateral ventricles in mutant DISC1 transgenic mice. Mol Psychiatry 2008; 13:115; PMID:18202691; http://dx.doi.org/10.1038/sj.mp.4002144.
    • (2008) Mol Psychiatry , vol.13 , pp. 115
    • Pletnikov, M.V.1    Ayhan, Y.2    Xu, Y.3    Nikolskaia, O.4    Ovanesov, M.5    Huang, H.6
  • 45
    • 35448988145 scopus 로고    scopus 로고
    • Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans
    • PMID:17675407
    • Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, Kong S, et al. Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proc Natl Acad Sci USA 2007; 104:14501-6; PMID:17675407; http://dx.doi.org/10.1073/pnas.0704774104.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14501-14506
    • Hikida, T.1    Jaaro-Peled, H.2    Seshadri, S.3    Oishi, K.4    Hookway, C.5    Kong, S.6
  • 46
    • 58149174266 scopus 로고    scopus 로고
    • Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1
    • PMID:18945897
    • Shen S, Lang B, Nakamoto C, Zhang F, Pu J, Kuan SL, et al. Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1. J Neurosci 2008; 28:10893-904; PMID:18945897; http://dx.doi.org/10.1523/JNEUROSCI.3299-08.2008.
    • (2008) J Neurosci , vol.28 , pp. 10893-10904
    • Shen, S.1    Lang, B.2    Nakamoto, C.3    Zhang, F.4    Pu, J.5    Kuan, S.L.6
  • 47
    • 0035878561 scopus 로고    scopus 로고
    • Chromosome 1 loci in Finnish schizophrenia families
    • PMID:11468279
    • Ekelund J, Hovatta I, Parker A, Paunio T, Varilo T, Martin R, et al. Chromosome 1 loci in Finnish schizophrenia families. Hum Mol Genet 2001; 10:1611-7; PMID:11468279; http://dx.doi.org/10.1093/hmg/10.15.1611.
    • (2001) Hum Mol Genet , vol.10 , pp. 1611-1617
    • Ekelund, J.1    Hovatta, I.2    Parker, A.3    Paunio, T.4    Varilo, T.5    Martin, R.6
  • 48
    • 25844501532 scopus 로고    scopus 로고
    • Genomewide linkage scan in schizoaffective disorder: Significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
    • PMID:16203953
    • Hamshere ML, Bennett P, Williams N, Segurado R, Cardno A, Norton N, et al. Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Arch Gen Psychiatry 2005; 62:1081-8; PMID:16203953; http://dx.doi.org/10.1001/ archpsyc.62.10.1081.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1081-1088
    • Hamshere, M.L.1    Bennett, P.2    Williams, N.3    Segurado, R.4    Cardno, A.5    Norton, N.6
  • 49
    • 0037953124 scopus 로고    scopus 로고
    • Linkage of schizophrenia with chromosome 1q loci in Taiwanese families
    • PMID:12740602
    • Hwu HG, Liu CM, Fann CS, Ou-Yang WC, Lee SF. Linkage of schizophrenia with chromosome 1q loci in Taiwanese families. Mol Psychiatry 2003; 8:445-52; PMID:12740602; http://dx.doi.org/10.1038/sj.mp.4001235.
    • (2003) Mol Psychiatry , vol.8 , pp. 445-452
    • Hwu, H.G.1    Liu, C.M.2    Fann, C.S.3    Ou-Yang, W.C.4    Lee, S.F.5
  • 50
    • 21844435448 scopus 로고    scopus 로고
    • Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population
    • PMID:15838535
    • Thomson PA, Wray NR, Millar JK, Evans KL, Hellard SL, Condie A, et al. Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Mol Psychiatry 2005; 10:657-68; PMID:15838535; http://dx.doi.org/10.1038/sj.mp.4001669.
    • (2005) Mol Psychiatry , vol.10 , pp. 657-668
    • Thomson, P.A.1    Wray, N.R.2    Millar, J.K.3    Evans, K.L.4    Hellard, S.L.5    Condie, A.6
  • 51
    • 32844455739 scopus 로고    scopus 로고
    • A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia
    • PMID:16103888
    • Hennah W, Tuulio-Henriksson A, Paunio T, Ekelund J, Varilo T, Partonen T, et al. A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia. Mol Psychiatry 2005; 10:1097-103; PMID:16103888; http://dx.doi.org/10.1038/sj.mp.4001731.
    • (2005) Mol Psychiatry , vol.10 , pp. 1097-1103
    • Hennah, W.1    Tuulio-Henriksson, A.2    Paunio, T.3    Ekelund, J.4    Varilo, T.5    Partonen, T.6
  • 52
    • 27744554247 scopus 로고    scopus 로고
    • Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter and impaired short- And long-term memory
    • PMID:16275808
    • Cannon TD, Hennah W, van Erp TG, Thompson PM, Lonnqvist J, Huttunen M, et al. Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter and impaired short- and long-term memory. Arch Gen Psychiatry 2005; 62:1205-13; PMID:16275808; http://dx.doi.org/10.1001/archpsyc.62.11.1205.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1205-1213
    • Cannon, T.D.1    Hennah, W.2    Van Erp, T.G.3    Thompson, P.M.4    Lonnqvist, J.5    Huttunen, M.6
  • 53
    • 34247465605 scopus 로고    scopus 로고
    • Positive association of the Disrupted-in-Schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han population
    • PMID:17286247
    • Qu M, Tang F, Yue W, Ruan Y, Lu T, Liu Z, et al. Positive association of the Disrupted-in-Schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han population. Am J Med Genet B Neuropsychiatr Genet 2007; 144:266-70; PMID:17286247; http://dx.doi.org/10.1002/ajmg.b.30322.
    • (2007) Am J Med Genet B Neuropsychiatr Genet , vol.144 , pp. 266-270
    • Qu, M.1    Tang, F.2    Yue, W.3    Ruan, Y.4    Lu, T.5    Liu, Z.6
  • 54
    • 34848875136 scopus 로고    scopus 로고
    • Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments
    • PMID:17673452
    • Palo OM, Antila M, Silander K, Hennah W, Kilpinen H, Soronen P, et al. Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments. Hum Mol Genet 2007; 16:2517-28; PMID:17673452; http://dx.doi.org/10.1093/hmg/ddm207.
    • (2007) Hum Mol Genet , vol.16 , pp. 2517-2528
    • Palo, O.M.1    Antila, M.2    Silander, K.3    Hennah, W.4    Kilpinen, H.5    Soronen, P.6
  • 55
    • 24044481269 scopus 로고    scopus 로고
    • Association between genotype at an exonic SNP in DISC1 and normal cognitive aging
    • PMID:16054297
    • Thomson PA, Harris SE, Starr JM, Whalley LJ, Porteous DJ, Deary IJ. Association between genotype at an exonic SNP in DISC1 and normal cognitive aging. Neurosci Lett 2005; 389:41-5; PMID:16054297; http://dx.doi.org/10.1016/j. neulet.2005.07.004.
    • (2005) Neurosci Lett , vol.389 , pp. 41-45
    • Thomson, P.A.1    Harris, S.E.2    Starr, J.M.3    Whalley, L.J.4    Porteous, D.J.5    Deary, I.J.6
  • 56
    • 33749576292 scopus 로고    scopus 로고
    • Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling
    • PMID:16959794
    • Hashimoto R, Numakawa T, Ohnishi T, Kumamaru E, Yagasaki Y, Ishimoto T, et al. Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Hum Mol Genet 2006; 15:3024-33; PMID:16959794; http://dx.doi.org/10.1093/hmg/ddl244.
    • (2006) Hum Mol Genet , vol.15 , pp. 3024-3033
    • Hashimoto, R.1    Numakawa, T.2    Ohnishi, T.3    Kumamaru, E.4    Yagasaki, Y.5    Ishimoto, T.6
  • 57
    • 38349191027 scopus 로고    scopus 로고
    • Association of DISC1 with autism and Asperger syndrome
    • PMID:17579608
    • Kilpinen H, Ylisaukko-Oja T, Hennah W, Palo OM, Varilo T, Vanhala R, et al. Association of DISC1 with autism and Asperger syndrome. Mol Psychiatry 2008; 13:187-96; PMID:17579608; http://dx.doi.org/10.1038/sj.mp.4002031.
    • (2008) Mol Psychiatry , vol.13 , pp. 187-196
    • Kilpinen, H.1    Ylisaukko-Oja, T.2    Hennah, W.3    Palo, O.M.4    Varilo, T.5    Vanhala, R.6
  • 58
    • 80051727525 scopus 로고    scopus 로고
    • DISC1-binding proteins in neural development, signalling and schizophrenia
    • PMID:21195721
    • Bradshaw NJ, Porteous DJ. DISC1-binding proteins in neural development, signalling and schizophrenia. Neuropharmacology 2010; PMID:21195721.
    • (2010) Neuropharmacology
    • Bradshaw, N.J.1    Porteous, D.J.2
  • 59
    • 77950619538 scopus 로고    scopus 로고
    • DISCopathies: Brain disorders related to DISC1 dysfunction
    • PMID:20397618
    • Korth C. DISCopathies: brain disorders related to DISC1 dysfunction. Rev Neurosci 2009; 20:321-30; PMID:20397618; http://dx.doi.org/10.1515/REVNEURO. 2009.20.5-6.321.
    • (2009) Rev Neurosci , vol.20 , pp. 321-330
    • Korth, C.1
  • 60
    • 38349114264 scopus 로고    scopus 로고
    • Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia
    • PMID:17848917
    • Pletnikov MV, Ayhan Y, Nikolskaia O, Xu Y, Ovanesov MV, Huang H, et al. Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia. Mol Psychiatry 2008; 13:173-86; PMID:17848917; http://dx.doi.org/10.1038/sj.mp.4002079.
    • (2008) Mol Psychiatry , vol.13 , pp. 173-186
    • Pletnikov, M.V.1    Ayhan, Y.2    Nikolskaia, O.3    Xu, Y.4    Ovanesov, M.V.5    Huang, H.6
  • 61
    • 34247619460 scopus 로고    scopus 로고
    • Behavioral phenotypes of Disc1 missense mutations in mice
    • PMID:17481393
    • Clapcote SJ, Lipina TV, Millar JK, Mackie S, Christie S, Ogawa F, et al. Behavioral phenotypes of Disc1 missense mutations in mice. Neuron 2007; 54:387-402; PMID:17481393; http://dx.doi.org/10.1016/j.neuron.2007.04.015.
    • (2007) Neuron , vol.54 , pp. 387-402
    • Clapcote, S.J.1    Lipina, T.V.2    Millar, J.K.3    Mackie, S.4    Christie, S.5    Ogawa, F.6
  • 62
    • 81255209206 scopus 로고    scopus 로고
    • Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse
    • PMID:21903668
    • Kuroda K, Yamada S, Tanaka M, Iizuka M, Yano H, Mori D, et al. Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Hum Mol Genet 2011; 20:4666-83; PMID:21903668; http://dx.doi.org/10.1093/hmg/ddr400.
    • (2011) Hum Mol Genet , vol.20 , pp. 4666-4683
    • Kuroda, K.1    Yamada, S.2    Tanaka, M.3    Iizuka, M.4    Yano, H.5    Mori, D.6
  • 63
    • 33845748185 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 Interactome: Evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
    • PMID:17043677
    • Camargo LM, Collura V, Rain JC, Mizuguchi K, Hermjakob H, Kerrien S, et al. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. Mol Psychiatry 2007; 12:74-86; PMID:17043677; http://dx.doi.org/10.1038/sj.mp. 4001880.
    • (2007) Mol Psychiatry , vol.12 , pp. 74-86
    • Camargo, L.M.1    Collura, V.2    Rain, J.C.3    Mizuguchi, K.4    Hermjakob, H.5    Kerrien, S.6
  • 64
    • 81455155113 scopus 로고    scopus 로고
    • DISC1: Structure, Function and Therapeutic Postential for Major Mental Illness
    • Soares CC, Carlyle BC, Bradshaw NJ, Porteous D. DISC1: Structure, Function and Therapeutic Postential for Major Mental Illness. ACS Chem Neurosci 2011; http://dx.doi.org/10.1021/cn200062k.
    • (2011) ACS Chem Neurosci
    • Soares, C.C.1    Carlyle, B.C.2    Bradshaw, N.J.3    Porteous, D.4
  • 65
    • 33744985583 scopus 로고    scopus 로고
    • DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex
    • PMID:16736468
    • Kirkpatrick B, Xu L, Cascella N, Ozeki Y, Sawa A, Roberts RC. DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. J Comp Neurol 2006; 497:436-50; PMID:16736468; http://dx.doi.org/10.1002/cne. 21007.
    • (2006) J Comp Neurol , vol.497 , pp. 436-450
    • Kirkpatrick, B.1    Xu, L.2    Cascella, N.3    Ozeki, Y.4    Sawa, A.5    Roberts, R.C.6
  • 66
    • 81555203199 scopus 로고    scopus 로고
    • Linking neurodevelopmental and synaptic theories of mental illness through DISC1
    • PMID:22095064
    • Brandon NJ, Sawa A. Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nat Rev Neurosci 2011; 12:707-22; PMID:22095064; http://dx.doi.org/10.1038/nrn3120.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 707-722
    • Brandon, N.J.1    Sawa, A.2
  • 67
    • 0034601620 scopus 로고    scopus 로고
    • The stanley foundation brain collection and neuropathology consortium
    • PMID:10913747
    • Torrey EF, Webster M, Knable M, Johnston N, Yolken RH. The stanley foundation brain collection and neuropathology consortium. Schizophr Res 2000; 44:151-5; PMID:10913747; http://dx.doi.org/10.1016/S0920-9964(99)00192-9.
    • (2000) Schizophr Res , vol.44 , pp. 151-155
    • Torrey, E.F.1    Webster, M.2    Knable, M.3    Johnston, N.4    Yolken, R.H.5
  • 68
    • 43049167463 scopus 로고    scopus 로고
    • Insolubility of disrupted-inschizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease
    • PMID:18400883
    • Leliveld SR, Bader V, Hendriks P, Prikulis I, Sajnani G, Requena JR, et al. Insolubility of disrupted-inschizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease. J Neurosci 2008; 28:3839-45; PMID:18400883; http://dx.doi.org/10.1523/JNEUROSCI.5389-07.2008.
    • (2008) J Neurosci , vol.28 , pp. 3839-3845
    • Leliveld, S.R.1    Bader, V.2    Hendriks, P.3    Prikulis, I.4    Sajnani, G.5    Requena, J.R.6
  • 69
    • 80052823280 scopus 로고    scopus 로고
    • Convergence of two independent mental disease genes on the protein level: Recruitment of dysbindin to cell-invasive disrupted-in- Schizophrenia 1 aggresomes
    • PMID:21531389
    • Ottis P, Bader V, Trossbach S, Kretzschmar H, Michel M, Leliveld SR, et al. Convergence of two independent mental disease genes on the protein level: recruitment of dysbindin to cell-invasive disrupted-in- schizophrenia 1 aggresomes. Biol Psychiatry 2011; 70:604-10; PMID:21531389; http://dx.doi.org/ 10.1016/j.biopsych.2011.03.027.
    • (2011) Biol Psychiatry , vol.70 , pp. 604-610
    • Ottis, P.1    Bader, V.2    Trossbach, S.3    Kretzschmar, H.4    Michel, M.5    Leliveld, S.R.6
  • 70
    • 16044373842 scopus 로고    scopus 로고
    • Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
    • PMID:8898202
    • Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, Hetherington C, et al. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 1996; 87:493-506; PMID:8898202; http://dx.doi.org/10.1016/S0092-8674(00)81369-0.
    • (1996) Cell , vol.87 , pp. 493-506
    • Mangiarini, L.1    Sathasivam, K.2    Seller, M.3    Cozens, B.4    Harper, A.5    Hetherington, C.6
  • 71
    • 3242806757 scopus 로고    scopus 로고
    • Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia
    • PMID:15184103
    • Blackwood DH, Muir WJ. Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia. Neurotox Res 2004; 6:35-41; PMID:15184103; http://dx.doi.org/10.1007/BF03033294.
    • (2004) Neurotox Res , vol.6 , pp. 35-41
    • Blackwood, D.H.1    Muir, W.J.2
  • 72
    • 0028859540 scopus 로고
    • Prion-inducing domain of yeast Ure2p and protease resistance of Ure2p in prion-containing cells
    • PMID:7569955
    • Masison DC, Wickner RB. Prion-inducing domain of yeast Ure2p and protease resistance of Ure2p in prion-containing cells. Science 1995; 270:93-5; PMID:7569955; http://dx.doi.org/10.1126/science.270.5233.93.
    • (1995) Science , vol.270 , pp. 93-95
    • Masison, D.C.1    Wickner, R.B.2
  • 73
    • 77957782470 scopus 로고    scopus 로고
    • Biology of amyloid: Structure, function and regulation
    • PMID:20947013
    • Greenwald J, Riek R. Biology of amyloid: structure, function and regulation. Structure 2010; 18:1244-60; PMID:20947013; http://dx.doi.org/10. 1016/j.str.2010.08.009.
    • (2010) Structure , vol.18 , pp. 1244-1260
    • Greenwald, J.1    Riek, R.2
  • 74
    • 79958110883 scopus 로고    scopus 로고
    • Alzheimer's pathogenesis: Is there neuron-to-neuron propagation?
    • PMID:21516512
    • Braak H, Del Tredici K. Alzheimer's pathogenesis: is there neuron-to-neuron propagation? Acta Neuropathol 2011; 121:589-95; PMID:21516512; http://dx.doi.org/10.1007/s00401-011-0825-z.
    • (2011) Acta Neuropathol , vol.121 , pp. 589-595
    • Braak, H.1    Del Tredici, K.2
  • 75
    • 79952449094 scopus 로고    scopus 로고
    • Prion hypothesis: The end of the controversy?
    • PMID:21130657
    • Soto C. Prion hypothesis: the end of the controversy? Trends Biochem Sci 2011; 36:151-8; PMID:21130657; http://dx.doi.org/10.1016/j.tibs.2010.11.001.
    • (2011) Trends Biochem Sci , vol.36 , pp. 151-158
    • Soto, C.1
  • 76
    • 33749020837 scopus 로고    scopus 로고
    • Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host
    • PMID:16990547
    • Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, et al. Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 2006; 313:1781-4; PMID:16990547; http://dx.doi.org/10. 1126/science.1131864.
    • (2006) Science , vol.313 , pp. 1781-1784
    • Meyer-Luehmann, M.1    Coomaraswamy, J.2    Bolmont, T.3    Kaeser, S.4    Schaefer, C.5    Kilger, E.6
  • 78
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • PMID:1759558
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991; 82:239-59; PMID:1759558; http://dx.doi.org/10. 1007/BF00308809.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 79
    • 0037333666 scopus 로고    scopus 로고
    • Staging of brain pathology related to sporadic Parkinson's disease
    • PMID:12498954
    • Braak H, Del Tredici K, Rüb U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 2003; 24:197-211; PMID:12498954; http://dx.doi.org/10.1016/S0197-4580(02) 00065-9.
    • (2003) Neurobiol Aging , vol.24 , pp. 197-211
    • Braak, H.1    Del Tredici, K.2    Rüb, U.3    De Vos, R.A.4    Jansen Steur, E.N.5    Braak, E.6
  • 80
    • 70350459011 scopus 로고    scopus 로고
    • Understanding the role of DISC1 in psychiatric disease and during normal development
    • PMID:19828788
    • Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A. Understanding the role of DISC1 in psychiatric disease and during normal development. J Neurosci 2009; 29:12768-75; PMID:19828788; http://dx.doi.org/10.1523/JNEUROSCI. 3355-09.2009.
    • (2009) J Neurosci , vol.29 , pp. 12768-12775
    • Brandon, N.J.1    Millar, J.K.2    Korth, C.3    Sive, H.4    Singh, K.K.5    Sawa, A.6
  • 81
    • 77955389367 scopus 로고    scopus 로고
    • Biochemical and functional interaction of disruptedin-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development
    • PMID:20685985
    • Young-Pearse TL, Suth S, Luth ES, Sawa A, Selkoe DJ. Biochemical and functional interaction of disruptedin-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development. J Neurosci 2010; 30:10431-40; PMID:20685985; http://dx.doi.org/10.1523/JNEUROSCI. 1445-10.2010.
    • (2010) J Neurosci , vol.30 , pp. 10431-10440
    • Young-Pearse, T.L.1    Suth, S.2    Luth, E.S.3    Sawa, A.4    Selkoe, D.J.5
  • 82
    • 62149083806 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling
    • PMID:19303846
    • Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, et al. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell 2009; 136:1017-31; PMID:19303846; http://dx.doi.org/10.1016/j.cell.2008.12.044.
    • (2009) Cell , vol.136 , pp. 1017-1031
    • Mao, Y.1    Ge, X.2    Frank, C.L.3    Madison, J.M.4    Koehler, A.N.5    Doud, M.K.6
  • 83
    • 27944502874 scopus 로고    scopus 로고
    • DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
    • PMID:16293762
    • Millar JK, Pickard BS, Mackie S, James R, Christie S, Buchanan SR, et al. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 2005; 310:1187-91; PMID:16293762; http://dx.doi.org/10. 1126/science.1112915.
    • (2005) Science , vol.310 , pp. 1187-1191
    • Millar, J.K.1    Pickard, B.S.2    Mackie, S.3    James, R.4    Christie, S.5    Buchanan, S.R.6
  • 84
    • 50949092420 scopus 로고    scopus 로고
    • Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: A candidate for psychiatric illnesses
    • PMID:18762586
    • Kamiya A, Tan PL, Kubo K, Engelhard C, Ishizuka K, Kubo A, et al. Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. Arch Gen Psychiatry 2008; 65:996-1006; PMID:18762586; http://dx.doi.org/10.1001/archpsyc.65.9.996.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 996-1006
    • Kamiya, A.1    Tan, P.L.2    Kubo, K.3    Engelhard, C.4    Ishizuka, K.5    Kubo, A.6
  • 85
    • 79955596140 scopus 로고    scopus 로고
    • DISC1-dependent switch from progenitor proliferation to migration in the developing cortex
    • PMID:21471969
    • Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature 2011; 473:92-6; PMID:21471969; http://dx.doi.org/10. 1038/nature09859.
    • (2011) Nature , vol.473 , pp. 92-96
    • Ishizuka, K.1    Kamiya, A.2    Oh, E.C.3    Kanki, H.4    Seshadri, S.5    Robinson, J.F.6
  • 86
    • 78650963274 scopus 로고    scopus 로고
    • Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions
    • PMID:21215370
    • Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, et al. Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions. Cell 2011; 144:67-78; PMID:21215370; http://dx.doi.org/10.1016/j.cell.2010.11.050.
    • (2011) Cell , vol.144 , pp. 67-78
    • Olzscha, H.1    Schermann, S.M.2    Woerner, A.C.3    Pinkert, S.4    Hecht, M.H.5    Tartaglia, G.G.6
  • 87
    • 55949127945 scopus 로고    scopus 로고
    • Association of the SerCys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding
    • PMID:19046394
    • Di Giorgio A, Blasi G, Sambataro F, Rampino A, Papazacharias A, Gambi F, et al. Association of the SerCys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding. Eur J Neurosci 2008; 28:2129-36; PMID:19046394; http://dx.doi.org/10.1111/j.1460-9568.2008.06482.x.
    • (2008) Eur J Neurosci , vol.28 , pp. 2129-2136
    • Di Giorgio, A.1    Blasi, G.2    Sambataro, F.3    Rampino, A.4    Papazacharias, A.5    Gambi, F.6
  • 88
    • 33750388150 scopus 로고    scopus 로고
    • DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1
    • PMID:17035248
    • Kamiya A, Tomoda T, Chang J, Takaki M, Zhan C, Morita M, et al. DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Hum Mol Genet 2006; 15:3313-23; PMID:17035248; http://dx.doi.org/10.1093/hmg/ddl407.
    • (2006) Hum Mol Genet , vol.15 , pp. 3313-3323
    • Kamiya, A.1    Tomoda, T.2    Chang, J.3    Takaki, M.4    Zhan, C.5    Morita, M.6
  • 89
    • 68849115810 scopus 로고    scopus 로고
    • Oligomer assembly of the C-terminal DISC1 domain (640854) is controlled by self-association motifs and disease-associated polymorphism S704C
    • PMID:19583211
    • Leliveld SR, Hendriks P, Michel M, Sajnani G, Bader V, Trossbach S, et al. Oligomer assembly of the C-terminal DISC1 domain (640-854) is controlled by self-association motifs and disease-associated polymorphism S704C. Biochemistry 2009; 48:7746-55; PMID:19583211; http://dx.doi.org/10.1021/bi900901e.
    • (2009) Biochemistry , vol.48 , pp. 7746-7755
    • Leliveld, S.R.1    Hendriks, P.2    Michel, M.3    Sajnani, G.4    Bader, V.5    Trossbach, S.6
  • 90
    • 83755181444 scopus 로고    scopus 로고
    • Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly
    • PMID:21998303
    • Narayanan S, Arthanari H, Wolfe MS, Wagner G. Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly. J Biol Chem 2011; 286:44266-76; PMID:21998303; http://dx.doi.org/10.1074/jbc.M111.271593.
    • (2011) J Biol Chem , vol.286 , pp. 44266-44276
    • Narayanan, S.1    Arthanari, H.2    Wolfe, M.S.3    Wagner, G.4
  • 91
    • 10744229990 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: Implications for schizophrenia and other major neurological disorders
    • PMID:14962739
    • Brandon NJ, Handford EJ, Schurov I, Rain JC, Pelling M, Duran-Jimeniz B, et al. Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders. Mol Cell Neurosci 2004; 25:42-55; PMID:14962739; http://dx.doi.org/10.1016/j.mcn.2003.09.009.
    • (2004) Mol Cell Neurosci , vol.25 , pp. 42-55
    • Brandon, N.J.1    Handford, E.J.2    Schurov, I.3    Rain, J.C.4    Pelling, M.5    Duran-Jimeniz, B.6
  • 92
    • 42049119895 scopus 로고    scopus 로고
    • Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells
    • PMID:18331715
    • Shen Y, Li N, Wu S, Zhou Y, Shan Y, Zhang Q, et al. Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells. Dev Cell 2008; 14:342-53; PMID:18331715; http://dx.doi.org/10.1016/j.devcel.2008.01.001.
    • (2008) Dev Cell , vol.14 , pp. 342-353
    • Shen, Y.1    Li, N.2    Wu, S.3    Zhou, Y.4    Shan, Y.5    Zhang, Q.6
  • 93
    • 77950430421 scopus 로고    scopus 로고
    • Disrupted-in-Schizphrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade
    • PMID:20212127
    • Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano SI, Hayashi-Takagi A, et al. Disrupted-in-Schizphrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci USA 2010; 107:5622-7; PMID:20212127; http://dx.doi.org/10.1073/pnas.0909284107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5622-5627
    • Seshadri, S.1    Kamiya, A.2    Yokota, Y.3    Prikulis, I.4    Kano, S.I.5    Hayashi-Takagi, A.6


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