-
1
-
-
0032693907
-
Genetic and non-genetic vulnerability factors in schizophrenia: The basis of the two hit hypothesis
-
Bayer TA, Falkai P, Maier W. 1999. Genetic and non-genetic vulnerability factors in schizophrenia: The basis of the "two hit hypothesis". J Psychiatr Res 33(6):543-548.
-
(1999)
J Psychiatr Res
, vol.33
, Issue.6
, pp. 543-548
-
-
Bayer, T.A.1
Falkai, P.2
Maier, W.3
-
2
-
-
0036902639
-
Mitochondrial dysfunction in schizophrenia: A possible linkage to dopamine
-
Ben-Shachar D. 2002. Mitochondrial dysfunction in schizophrenia: A possible linkage to dopamine. J Neurochem 83(6):1241-1251.
-
(2002)
J Neurochem
, vol.83
, Issue.6
, pp. 1241-1251
-
-
Ben-Shachar, D.1
-
3
-
-
0034927864
-
Schizophrenia and affective disorders - cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family
-
Blackwood DH, Fordyce A, Walker MT, St Clair DM, Porteous DJ, Muir WJ. 2001. Schizophrenia and affective disorders - cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family. Am J Hum Genet 69(2) 428-433.
-
(2001)
Am J Hum Genet
, vol.69
, Issue.2
, pp. 428-433
-
-
Blackwood, D.H.1
Fordyce, A.2
Walker, M.T.3
St Clair, D.M.4
Porteous, D.J.5
Muir, W.J.6
-
4
-
-
10744229990
-
Disrupted in schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: Implications for schizophrenia and other major neurological disorders
-
Brandon NJ, Handford EJ, Schurov I, Rain JC, Pelling M, Duran-Jimeniz B, Camargo LM, Oliver KR, Beher D, Shearman MS, et al. 2004. Disrupted in schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: Implications for schizophrenia and other major neurological disorders. Mol Cell Neurosci 25(1):42-55.
-
(2004)
Mol Cell Neurosci
, vol.25
, Issue.1
, pp. 42-55
-
-
Brandon, N.J.1
Handford, E.J.2
Schurov, I.3
Rain, J.C.4
Pelling, M.5
Duran-Jimeniz, B.6
Camargo, L.M.7
Oliver, K.R.8
Beher, D.9
Shearman, M.S.10
-
5
-
-
24044449980
-
DISCI and neurocognitive function in schizophrenia
-
Burdick KE, Hodgkinson CA, Szeszko PR, Lencz T, Ekholm JM, Kane JM, Goldman D, Malhotra AK. 2005. DISCI and neurocognitive function in schizophrenia. Neuroreport 16(12):1399-1402.
-
(2005)
Neuroreport
, vol.16
, Issue.12
, pp. 1399-1402
-
-
Burdick, K.E.1
Hodgkinson, C.A.2
Szeszko, P.R.3
Lencz, T.4
Ekholm, J.M.5
Kane, J.M.6
Goldman, D.7
Malhotra, A.K.8
-
6
-
-
20844463251
-
Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia
-
Callicott JH, Straub RE, Pezawas L, Egan MF, Mattay VS, Hariri AR, Verchinski BA, Meyer-Lindenberg A, Balkissoon R, Kolachana B, et al. 2005. Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc Natl Acad Sci USA 102(24): 8627-8632.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.24
, pp. 8627-8632
-
-
Callicott, J.H.1
Straub, R.E.2
Pezawas, L.3
Egan, M.F.4
Mattay, V.S.5
Hariri, A.R.6
Verchinski, B.A.7
Meyer-Lindenberg, A.8
Balkissoon, R.9
Kolachana, B.10
-
7
-
-
0031939076
-
The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study
-
Cannon TD, Kaprio J, Lonnqvist J, Huttunen M, Koskenvuo M. 1998. The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study. Arch Gen Psychiatry 55(1):67-74.
-
(1998)
Arch Gen Psychiatry
, vol.55
, Issue.1
, pp. 67-74
-
-
Cannon, T.D.1
Kaprio, J.2
Lonnqvist, J.3
Huttunen, M.4
Koskenvuo, M.5
-
8
-
-
12444256025
-
Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q
-
Curtis D, Kalsi G, Brynjolfsson J, McInnis M, O'Neill J, Smyth C, Moloney E, Murphy P, McQuillin A, Petursson H, et al. 2003. Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q. Psychiatr Genet 13(2):77-84.
-
(2003)
Psychiatr Genet
, vol.13
, Issue.2
, pp. 77-84
-
-
Curtis, D.1
Kalsi, G.2
Brynjolfsson, J.3
McInnis, M.4
O'Neill, J.5
Smyth, C.6
Moloney, E.7
Murphy, P.8
McQuillin, A.9
Petursson, H.10
-
9
-
-
0034941967
-
Identification of polymorphisms within disrupted in schizophrenia 1 and disrupted in schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder
-
Devon RS, Anderson S, Teague PW, Burgess P, Kipari TM, Semple CA, Millar JK, Muir WJ, Murray V, Pelosi AJ, et al. 2001. Identification of polymorphisms within disrupted in schizophrenia 1 and disrupted in schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder. Psychiatr Genet 11(2):71-78.
-
(2001)
Psychiatr Genet
, vol.11
, Issue.2
, pp. 71-78
-
-
Devon, R.S.1
Anderson, S.2
Teague, P.W.3
Burgess, P.4
Kipari, T.M.5
Semple, C.A.6
Millar, J.K.7
Muir, W.J.8
Murray, V.9
Pelosi, A.J.10
-
10
-
-
0035878561
-
Chromosome 1 loci in Finnish schizophrenia families
-
Ekelund J, Hovatta I, Parker A, Paunio T, Varilo T, Martin R, Suhonen J, Ellonen P, Chan G, Sinsheimer JS, et al. 2001. Chromosome 1 loci in Finnish schizophrenia families. Hum Mol Genet 10(15):1611-1617.
-
(2001)
Hum Mol Genet
, vol.10
, Issue.15
, pp. 1611-1617
-
-
Ekelund, J.1
Hovatta, I.2
Parker, A.3
Paunio, T.4
Varilo, T.5
Martin, R.6
Suhonen, J.7
Ellonen, P.8
Chan, G.9
Sinsheimer, J.S.10
-
11
-
-
8744231685
-
Replication of 1q42 linkage in Finnish schizophrenia pedigrees
-
Ekelund J, Hennah W, Hiekkalinna T, Parker A, Meyer J, Lonnqvist J, Peltonen L. 2004. Replication of 1q42 linkage in Finnish schizophrenia pedigrees. Mol Psychiatry 9(11):1037-1041.
-
(2004)
Mol Psychiatry
, vol.9
, Issue.11
, pp. 1037-1041
-
-
Ekelund, J.1
Hennah, W.2
Hiekkalinna, T.3
Parker, A.4
Meyer, J.5
Lonnqvist, J.6
Peltonen, L.7
-
12
-
-
0042780286
-
Genetic linkage and association between chromosome 1q and working memory function in schizophrenia
-
Gasperoni TL, Ekelund J, Huttunen M, Palmer CG, Tuulio-Henriksson A, Lonnqvist J, Kaprio J, Peltonen L, Cannon TD. 2003. Genetic linkage and association between chromosome 1q and working memory function in schizophrenia. Am J Med Genet Part B 116B:8-16.
-
(2003)
Am J Med Genet
, vol.116 B
, Issue.PART B
, pp. 8-16
-
-
Gasperoni, T.L.1
Ekelund, J.2
Huttunen, M.3
Palmer, C.G.4
Tuulio-Henriksson, A.5
Lonnqvist, J.6
Kaprio, J.7
Peltonen, L.8
Cannon, T.D.9
-
13
-
-
0032924127
-
The neuropathology of schizophrenia. A critical review of the data and their interpretation
-
Harrison PJ. 1999. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain 122(Pt 4):593-624.
-
(1999)
Brain
, vol.122
, Issue.PART 4
, pp. 593-624
-
-
Harrison, P.J.1
-
14
-
-
0028023599
-
Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]
-
Hattori M, Adachi H, Tsujimoto M, Arai H, Inoue K. 1994. Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]. Nature 370(6486):216-218.
-
(1994)
Nature
, vol.370
, Issue.6486
, pp. 216-218
-
-
Hattori, M.1
Adachi, H.2
Tsujimoto, M.3
Arai, H.4
Inoue, K.5
-
15
-
-
0345530985
-
Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects
-
Hennah W, Varilo T, Kestila M, Paunio T, Arajarvi R, Haukka J, Parker A, Martin R, Levitzky S, Partonen T, et al. 2003. Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects. Hum Mol Genet 12(23):3151-3159.
-
(2003)
Hum Mol Genet
, vol.12
, Issue.23
, pp. 3151-3159
-
-
Hennah, W.1
Varilo, T.2
Kestila, M.3
Paunio, T.4
Arajarvi, R.5
Haukka, J.6
Parker, A.7
Martin, R.8
Levitzky, S.9
Partonen, T.10
-
16
-
-
6344255274
-
Disrupted in schizophrenia 1 (DISC1): Association with schizophrenia, schizoaffective disorder, and bipolar disorder
-
Hodgkinson CA, Goldman D, Jaeger J, Persaud S, Kane JM, Lipsky RH, Malhotra AK. 2004. Disrupted in schizophrenia 1 (DISC1): Association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am J Hum Genet 75(5):862-872.
-
(2004)
Am J Hum Genet
, vol.75
, Issue.5
, pp. 862-872
-
-
Hodgkinson, C.A.1
Goldman, D.2
Jaeger, J.3
Persaud, S.4
Kane, J.M.5
Lipsky, R.H.6
Malhotra, A.K.7
-
17
-
-
0037953124
-
Linkage of schizophrenia with chromosome 1q loci in Taiwanese families
-
Hwu HG, Liu CM, Fann CS, Ou-Yang WC, Lee SF. 2003. Linkage of schizophrenia with chromosome 1q loci in Taiwanese families. Mol Psychiatry 8(4):445-452.
-
(2003)
Mol Psychiatry
, vol.8
, Issue.4
, pp. 445-452
-
-
Hwu, H.G.1
Liu, C.M.2
Fann, C.S.3
Ou-Yang, W.C.4
Lee, S.F.5
-
18
-
-
4444315059
-
Association study of polymorphisms in the 5′ upstream region of human DISC1 gene with schizophrenia
-
Kockelkorn TT, Arai M, Matsumoto H, Fukuda N, Yamada K, Minabe Y, Toyota T, Ujike H, Sora I, Mori N, et al. 2004. Association study of polymorphisms in the 5′ upstream region of human DISC1 gene with schizophrenia. Neurosci Lett 368(1):41-45.
-
(2004)
Neurosci Lett
, vol.368
, Issue.1
, pp. 41-45
-
-
Kockelkorn, T.T.1
Arai, M.2
Matsumoto, H.3
Fukuda, N.4
Yamada, K.5
Minabe, Y.6
Toyota, T.7
Ujike, H.8
Sora, I.9
Mori, N.10
-
19
-
-
0029131849
-
Genetic basis of schizophrenia
-
McGuffin P, Owen MJ, Farmer AE. 1995. Genetic basis of schizophrenia. Lancet 346(8976):678-682.
-
(1995)
Lancet
, vol.346
, Issue.8976
, pp. 678-682
-
-
McGuffin, P.1
Owen, M.J.2
Farmer, A.E.3
-
20
-
-
0034235003
-
Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia
-
Millar JK, Christie S, Semple CA, Porteous DJ. 2000a. Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia. Genomics 67(1):69-77.
-
(2000)
Genomics
, vol.67
, Issue.1
, pp. 69-77
-
-
Millar, J.K.1
Christie, S.2
Semple, C.A.3
Porteous, D.J.4
-
21
-
-
0034702026
-
Disruption of two novel genes by a translocation co-segregating with schizophrenia
-
Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, Devon RS, Clair DM, Muir WJ, Blackwood DH, et al. 2000b. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet 9(9):1415-1423.
-
(2000)
Hum Mol Genet
, vol.9
, Issue.9
, pp. 1415-1423
-
-
Millar, J.K.1
Wilson-Annan, J.C.2
Anderson, S.3
Christie, S.4
Taylor, M.S.5
Semple, C.A.6
Devon, R.S.7
Clair, D.M.8
Muir, W.J.9
Blackwood, D.H.10
-
22
-
-
0242437914
-
Yeast two-hybrid screens implicate DISC1 in brain development and function
-
Millar JK, Christie S, Porteous DJ. 2003. Yeast two-hybrid screens implicate DISC1 in brain development and function. Biochem Biophys Res Commun 311(4):1019-1025.
-
(2003)
Biochem Biophys Res Commun
, vol.311
, Issue.4
, pp. 1019-1025
-
-
Millar, J.K.1
Christie, S.2
Porteous, D.J.3
-
23
-
-
4544339685
-
DISC1 and DISC2: Discovering and dissecting molecular mechanisms underlying psychiatric illness
-
Millar JK, James R, Brandon NJ, Thomson PA. 2004. DISC1 and DISC2: Discovering and dissecting molecular mechanisms underlying psychiatric illness. Ann Med 36(5):367-378.
-
(2004)
Ann Med
, vol.36
, Issue.5
, pp. 367-378
-
-
Millar, J.K.1
James, R.2
Brandon, N.J.3
Thomson, P.A.4
-
24
-
-
0042622356
-
Disrupted-in-schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth
-
Miyoshi K, Honda A, Baba K, Taniguchi M, Oono K, Fujita T, Kuroda S, Katayama T, Tohyama M. 2003. Disrupted-in-schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol Psychiatry 8(7):685-694.
-
(2003)
Mol Psychiatry
, vol.8
, Issue.7
, pp. 685-694
-
-
Miyoshi, K.1
Honda, A.2
Baba, K.3
Taniguchi, M.4
Oono, K.5
Fujita, T.6
Kuroda, S.7
Katayama, T.8
Tohyama, M.9
-
25
-
-
0037766786
-
DISC1 (Disrupted-in- schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: Regulation and loss of interaction with mutation
-
Morris JA, Kandpal G, Ma L, Austin CP. 2003. DISC1 (Disrupted-in- schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: Regulation and loss of interaction with mutation. Hum Mol Genet 12(13):1591-1608.
-
(2003)
Hum Mol Genet
, vol.12
, Issue.13
, pp. 1591-1608
-
-
Morris, J.A.1
Kandpal, G.2
Ma, L.3
Austin, C.P.4
-
26
-
-
0034520636
-
NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein
-
Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH. 2000. NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron 28(3):697-711.
-
(2000)
Neuron
, vol.28
, Issue.3
, pp. 697-711
-
-
Niethammer, M.1
Smith, D.S.2
Ayala, R.3
Peng, J.4
Ko, J.5
Lee, M.S.6
Morabito, M.7
Tsai, L.H.8
-
27
-
-
0037422609
-
Disrupted-in-schizophrenia-1 (DISC-1): Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth
-
Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, et al. 2003. Disrupted-in-schizophrenia-1 (DISC-1): Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proc Natl Acad Sci USA 100(1):289-294.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.1
, pp. 289-294
-
-
Ozeki, Y.1
Tomoda, T.2
Kleiderlein, J.3
Kamiya, A.4
Bord, L.5
Fujii, K.6
Okawa, M.7
Yamada, N.8
Hatten, M.E.9
Snyder, S.H.10
-
28
-
-
0034520597
-
A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system
-
Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S. 2000. A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron 28(3):681-696.
-
(2000)
Neuron
, vol.28
, Issue.3
, pp. 681-696
-
-
Sasaki, S.1
Shionoya, A.2
Ishida, M.3
Gambello, M.J.4
Yingling, J.5
Wynshaw-Boris, A.6
Hirotsune, S.7
-
29
-
-
0037177552
-
Schizophrenia: Diverse approaches to a complex disease
-
Sawa A, Snyder SH. 2002. Schizophrenia: Diverse approaches to a complex disease. Science 296(5568):692-695.
-
(2002)
Science
, vol.296
, Issue.5568
, pp. 692-695
-
-
Sawa, A.1
Snyder, S.H.2
-
30
-
-
18944381751
-
SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci
-
Shi YY, He L. 2005. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 15(2):97-98.
-
(2005)
Cell Res
, vol.15
, Issue.2
, pp. 97-98
-
-
Shi, Y.Y.1
He, L.2
-
31
-
-
0025277392
-
Association within a family of a balanced autosomal translocation with major mental illness
-
St Clair D, Blackwood D, Muir W, Carothers A, Walker M, Spowart G, Gosden C, Evans HJ. 1990. Association within a family of a balanced autosomal translocation with major mental illness. Lancet 336(8706): 13-16.
-
(1990)
Lancet
, vol.336
, Issue.8706
, pp. 13-16
-
-
St Clair, D.1
Blackwood, D.2
Muir, W.3
Carothers, A.4
Walker, M.5
Spowart, G.6
Gosden, C.7
Evans, H.J.8
-
32
-
-
0035111299
-
NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins
-
Sweeney KJ, Prokscha A, Eichele G. 2001. NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins. Mech Dev 101(1-2):21-33.
-
(2001)
Mech Dev
, vol.101
, Issue.1-2
, pp. 21-33
-
-
Sweeney, K.J.1
Prokscha, A.2
Eichele, G.3
-
33
-
-
24044481269
-
Association between genotype at an exonic SNP in DISC1 and normal cognitive aging
-
Thomson PA, Harris SE, Starr JM, Whalley LJ, Porteous DJ, Deary IJ. 2005a. Association between genotype at an exonic SNP in DISC1 and normal cognitive aging. Neurosci Lett 389(1):41-45.
-
(2005)
Neurosci Lett
, vol.389
, Issue.1
, pp. 41-45
-
-
Thomson, P.A.1
Harris, S.E.2
Starr, J.M.3
Whalley, L.J.4
Porteous, D.J.5
Deary, I.J.6
-
34
-
-
21844435448
-
Association between the TRAX/ DISC locus and both bipolar disorder and schizophrenia in the Scottish population
-
616
-
Thomson PA, Wray NR, Millar JK, Evans KL, Hellard SL, Condie A, Muir WJ, Blackwood DH, Porteous DJ. 2005b. Association between the TRAX/ DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Mol Psychiatry 10(7):657-668 , 616.
-
(2005)
Mol Psychiatry
, vol.10
, Issue.7
, pp. 657-668
-
-
Thomson, P.A.1
Wray, N.R.2
Millar, J.K.3
Evans, K.L.4
Hellard, S.L.5
Condie, A.6
Muir, W.J.7
Blackwood, D.H.8
Porteous, D.J.9
-
35
-
-
32244433189
-
Genetic association between schizophrenia and the DISC1 gene in the Scottish population
-
Zhang F, Sarginson J, Crombie C, Walker N, Stclair D, Shaw D. 2006. Genetic association between schizophrenia and the DISC1 gene in the Scottish population. Am J Med Genet Part B 141B:155-159.
-
(2006)
Am J Med Genet
, vol.141 B
, Issue.PART B
, pp. 155-159
-
-
Zhang, F.1
Sarginson, J.2
Crombie, C.3
Walker, N.4
Stclair, D.5
Shaw, D.6
|