Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific protease 1 expression

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Huang, Weiwei ^a   He, Tiantian ^a,b   Chai, Chengsen ^a   Yang, Yuan ^a   Zheng, Yahong ^a   Zhou, Pei ^a   Qiao, Xiaoxia ^a   Zhang, Bin ^a   Liu, Zengzhen ^a   Wang, Junru ^a   Shi, Changhong ^c   Lei, Liping ^d   Gao, Kun ^e   Li, Hewei ^f   Zhong, Sue ^d   Yao, Libo ^c   Huang, Meng Er ^b   Lei, Ming ^a  

^a NORTHWEST A F UNIVERSITY   (China)

^b CNRS   (France)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d Xi'an San Yao Bio pharmaceutical Corporation   (China)

^e LANZHOU UNIVERSITY   (China)

^f BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; CASPASE; CELASTROL; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN C JUN; PROTEINASE; SUMO SPECIFIC PROTEASE 1; TRIPTOLIDE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DITERPENE; EPOXIDE; PHENANTHRENE DERIVATIVE; SENP1 PROTEIN, HUMAN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL GROWTH; CELL LINE; CELL PROLIFERATION; CELL STRAIN LNCAP; CELL STRAIN PC 3; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENCY; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROSTATE CANCER; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SUMOYLATION; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; DISEASE COURSE; DRUG EFFECT; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

MUS MUSCULUS; TRIPTERYGIUM WILFORDII;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE PROGRESSION; DITERPENES; DOWN-REGULATION; ENDOPEPTIDASES; EPOXY COMPOUNDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; PHENANTHRENES; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; RNA, MESSENGER; TRANSCRIPTION, GENETIC; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84861590032     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037693     Document Type: Article

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