Androgen receptor status of lymph node metastases from prostate cancer

Prostate

Volumn 28, Issue 2, 1996, Pages 129-135

  Hobisch, Alfred ^a   Culig, Zoran ^a   Radmayr, Christian ^a   Bartsch, Georg ^a   Klocker, Helmut ^a   Hittmair, Anton ^b  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

androgen receptor; immunohistochemistry; localized prostate cancer; lymph node metastasis

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR;

ARTICLE; CANCER STAGING; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CARCINOMA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPH NODES; LYMPHATIC METASTASIS; MALE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN;

EID: 0030024517     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(199602)28:2<129::AID-PROS9>3.0.CO;2-B     Document Type: Article

References (34)

1. Barrack ER, Tindall DJ: A critical evaluation of the use of androgen receptor assays to predict the androgen responsiveness of prostatic cancer. Prog Clin Biol Res 239:155-187, 1987.
2. Ruizeveld de Winter JA, Trapman J, Brinkmann AO, Boersma WJA, Mulder E, Schroeder FH, Claassen E, Van der Kwast TH: Androgen receptor heterogeneity in human prostatic carcinomas visualized by immunohistochemistry. J Pathol 161:329-332, 1990.
3. Van der Kwast TH, Schalken J, Ruizeveld de Winter JA, Van Vroonhoven CCJ, Mulder E, Boersma W, Trapman J: Androgen receptor in endocrine therapy-resistant human prostate cancer. Int J Cancer 48:189-193, 1991.
4. Sultan C, Lumbroso S, Poujol N, Belon C, Boudon C, Lobaccaro JM: Mutations of androgen receptor gene in androgen insensitivity syndromes. J Steroid Biochem Mol Biol 46:519-530, 1993.
5. Newmark JR, Hardy DO, Tonb DC, Carter BS, Epstein JI, Isaacs WB, Brown TR, Barrack ER: Androgen receptor gene mutations in human prostate cancer. Proc Natl Acad Sci USA 89:6319-6323, 1992.
6. Culig Z, Klocker H, Eberle J, Kaspar F, Hobisch A, Cronauer MV, Bartsch G: DNA sequence of the androgen receptor in prostatic tumor cell lines and tissue specimens assessed by means of the polymerase chain reaction. Prostate 22:11-22, 1993.
7. Culig Z, Hobisch A, Cronauer M, Cato ACB, Hittmair A, Radmayr C, Eberle J, Bartsch G, Klocker H: Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone. Mol Endocrinol 7:1541-1550, 1993.
8. Suzuki H, Sato N, Watabe Y, Masai M, Seino S, Shimazaki J: Androgen receptor gene mutations in human prostate cancer. J Steroid Biochem Mol Biol 46:759-765, 1993.
9. Ruizeveld de Winter JA, Janssen PJA, Sleddens HMEB, Verleun-Mooijman MCT, Trapman J, Brinkmann AO, Santerse AB, Schröder FH, Van der Kwast TH: Androgen receptor status in localized and locally progressive hormone refractory human prostate cancer. Am J Pathol 144:735-746, 1994.
10. Gaddipati JP, McLeod DG, Heidenberg HB, Sesterhenn IA, Finger MJ, Moul JW, Srivastava S: Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers. Cancer Res 54:2861-2864, 1994.
11. Trapman J, Ris-Stalpers C, Van der Korput JAGM, Kuiper GGJM, Faber PW, Romijn JC, Mulder E, Brinkmann AO: The androgen receptor: Functional structure and expression in transplanted human prostate tumours and prostate tumour cell lines. J Steroid Biochem Mol Biol 37:837-842, 1990.
12. Tilley WD, Wilson CM, Marcelli M, McPhaul MJ: Androgen receptor gene expression in human prostate carcinoma cell lines. Cancer Res 50:5382-5386, 1990.
13. Mostofi FK, Sesterhenn IA, Sobin LH: "Histological Typing of Prostate Tumors." Geneve: WHO Monograph Series No 22, 1980.
14. Prins GS, Birch L, Greene GL: Androgen receptor localization in different cell types of the adult rat prostate. Endocrinology 129:3187-3199, 1991.
15. Hittmair A, Schmid KW: Inhibition of endogenous peroxidase for the immunohistochemical demonstration of intermediate filament proteins (IFP). J Immunol Methods 116:199-205, 1989.
16. Young CYF, Montgomery BT, Andrews PE, Qiu S, Bilhartz DL, Tindall DJ: Hormonal regulation of prostate-specific antigen messenger RNA in human prostatic adenocarcinoma cell line LNCaP. Cancer Res 51:3748-3752, 1991.
17. Montgomery BT, Young CYF, Bilhartz DL, Andrews PE, Prescott JL, Thompson NF, Tindall DJ: Hormonal regulation of prostate-specific antigen (PSA) glycoprotein in the human prostatic adenocarcinoma cell line, LNCaP. Prostate 21:63-73, 1992.
18. Geller J, Candari CD: Comparison of dihydrotestosterone levels in prostatic cancer metastases and primary prostate cancer. Prostate 15:171-175, 1989.
19. Quarmby VE, Beckman WC Jr, Cooke DB, Lubahn DB, Joseph DR, Wilson EM, French FS: Expression and localization of androgen receptor in the R-3327 Dunning rat prostatic adenocarcinoma. Cancer Res 50:735-739, 1990.
20. Hsieh J-T, Wu H-C, Gleave ME, Von Eschenbach AC, Chung LWK: Autocrine regulation of prostate-specific antigen gene expression in a human prostatic cancer (LNCaP) subline. Cancer Res 53:2852-2857, 1993.
21. Riegman PHJ, Vlietstra RJ, Van der Korput JAGM, Brinkmann AO, Trapman J: The promoter of the prostate-specific antigen contains a functional androgen responsive element. Mol Endocrinol 5:1921-1930, 1991.
22. Sadi MV, Walsh PC, Barrack ER: Immunohistochemical study of androgen receptors in metastatic prostate cancer. Cancer 67:3057-3064, 1991.
23. Sadi MV, Barrack ER: Image analysis of androgen receptor immunostaining in metastatic prostate cancer. Cancer 71:2574-2580, 1993.
24. Tilley WD, Lim-Tio SS, Horsfall DJ, Aspinall JO, Marshall VR, Skinner JM: Detection of discrete androgen receptor epitopes in prostate cancer by immunostaining: Measurement by color video image analysis. Cancer Res 54:4096-4102, 1994.
25. Ekman P, Brolin J: Steroid receptor profile in human prostate cancer metastases as compared with primary prostatic carcinoma. Prostate 18:147-153, 1991.
26. King WJ, Greene GL: Monoclonal antibodies recognize oestrogen receptor in the nuclei of target cells. Nature 307:745-749, 1984.
27. Veldscholte J, Ris-Stalpers C, Kuiper GGJM, Jenster G, Berrevoets C, Claassen E, Van Rooij HCJ, Trapman J, Brinkmann AO, Mulder E: A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgen. Biochem Biophys Res Commun 173:534-540, 1990.
28. Hobisch A, Culig Z, Cato ACB, Denninger A, Trapman J, Radmayr C, Bartsch G, Klocker H: Products of dihydrotestosterone metabolism activate a mutant androgen receptor detected in a late stage prostatic carcinoma. Urol Res 21:446, 1993.
29. Culig Z, Hobisch A, Cronauer MV, Radmayr C, Trapman J, Hittmair A, Bartsch G, Klocker H: Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I keratinocyte growth factor and epidermal growth factor. Cancer Res 54:5474-5478, 1994.
30. Aronica SM, Katzenellenbogen BS: Stimulation of estrogen receptor-mediated transcription and alteration of the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate and insulin-like growth factor I. Mol Endocrinol 7:742-753, 1993.
31. Sartorius CA, Groshong SD, Miller LA, Powell RL, Tung L, Takimoto GS, Horwitz KB: New T47D breast cancer cell lines for the independent study of progesterone B- and A- receptors: Only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP. Cancer Res 54:3868-3877, 1994.
32. Cho H, Katzenellenbogen BS: Synergistic activation of estrogen receptor-mediated transcription by estradiol and protein kinase activators. Mol Endocrinol 7:441-452, 1993.
33. Power RF, Mani SK, Codina J, Connely OM, O'Malley BW: Dopaminergic and ligand-independent activation of steroid hormone receptors. Science 254:1636-1639, 1992.
34. Young CYF, Murtha PE, Andrews PE, Lindzey JK, Tindall DJ: Antagonism of androgen action in prostate tumor cells by retinoic acid. Prostate 25:39-45, 1994.