메뉴 건너뛰기




Volumn 16, Issue 11, 2009, Pages 1006-1013

Effects of triptolide from Tripterygium wilfordii on ERα and p53 expression in two human breast cancer cell lines

Author keywords

Estrogen receptor alpha; Human breast cancer cells; P53; Tripterygium wilfordii; Triptolide

Indexed keywords

ESTROGEN RECEPTOR ALPHA; PROTEIN P53; TRIPTERYGIUM WILFORDII EXTRACT; TRIPTOLIDE;

EID: 70349768102     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2009.03.021     Document Type: Article
Times cited : (58)

References (35)
  • 1
    • 0034485142 scopus 로고    scopus 로고
    • Estrogen receptor alpha in human breast cancer: occurrence and significance
    • Ali S., and Coombes R.C. Estrogen receptor alpha in human breast cancer: occurrence and significance. Journal of Mammary Gland Biology and Neoplasia 5 (2000) 271-281
    • (2000) Journal of Mammary Gland Biology and Neoplasia , vol.5 , pp. 271-281
    • Ali, S.1    Coombes, R.C.2
  • 2
    • 19544390715 scopus 로고    scopus 로고
    • Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects
    • Arathi R., Setty M.D., Leonard H., and Sigal M.D. Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects. Seminars in Arthritis and Rheumatism 6 (2005) 773-784
    • (2005) Seminars in Arthritis and Rheumatism , vol.6 , pp. 773-784
    • Arathi, R.1    Setty, M.D.2    Leonard, H.3    Sigal, M.D.4
  • 3
    • 0035904394 scopus 로고    scopus 로고
    • The effects of wild-type P53 tumor suppressor activity and mutant P53 gain-of-function on cell growth
    • Cadwell C., and Zambetti G.P. The effects of wild-type P53 tumor suppressor activity and mutant P53 gain-of-function on cell growth. Gene 277 (2001) 15-30
    • (2001) Gene , vol.277 , pp. 15-30
    • Cadwell, C.1    Zambetti, G.P.2
  • 5
    • 0034909663 scopus 로고    scopus 로고
    • Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F
    • Chen B.J. Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F. Leukemia & lymphoma 3 (2001) 253-265
    • (2001) Leukemia & lymphoma , vol.3 , pp. 253-265
    • Chen, B.J.1
  • 6
    • 28944432804 scopus 로고    scopus 로고
    • Multidrug resistance/Pglycoprotein and breast cancer: review and meta-analysis
    • Clarke R., Leonessa F., and Trock B. Multidrug resistance/Pglycoprotein and breast cancer: review and meta-analysis. Seminars in Oncology 32 (2005) S9-S15
    • (2005) Seminars in Oncology , vol.32
    • Clarke, R.1    Leonessa, F.2    Trock, B.3
  • 7
    • 34447293528 scopus 로고    scopus 로고
    • Experimental AA amyloidosis in mice is inhibited by treatment with triptolide, a purified traditional Chinese medicine
    • Cui D., Hoshii Y., Kawano H., Sugiyama S., Gondo T., Liu Y., and Ishihara T. Experimental AA amyloidosis in mice is inhibited by treatment with triptolide, a purified traditional Chinese medicine. International Immunopharmacology 7 (2007) 1232-1240
    • (2007) International Immunopharmacology , vol.7 , pp. 1232-1240
    • Cui, D.1    Hoshii, Y.2    Kawano, H.3    Sugiyama, S.4    Gondo, T.5    Liu, Y.6    Ishihara, T.7
  • 8
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • Evan G.I., and Vousden K.H. Proliferation, cell cycle and apoptosis in cancer. Nature 411 (2001) 245-248
    • (2001) Nature , vol.411 , pp. 245-248
    • Evan, G.I.1    Vousden, K.H.2
  • 9
    • 0642287879 scopus 로고    scopus 로고
    • PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy
    • Fidler J.M., Li K., Chung C., Wei K., Ross J.A., Gao M., and Rosen G.D. PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy. Molecular Cancer Therapeutics 2 (2003) 855-862
    • (2003) Molecular Cancer Therapeutics , vol.2 , pp. 855-862
    • Fidler, J.M.1    Li, K.2    Chung, C.3    Wei, K.4    Ross, J.A.5    Gao, M.6    Rosen, G.D.7
  • 11
    • 0034735853 scopus 로고    scopus 로고
    • Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer
    • Gustafsson J.A., and Warner M. Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer. The Journal of Steroid Biochemistry and Molecular Biology 74 (2000) 245-248
    • (2000) The Journal of Steroid Biochemistry and Molecular Biology , vol.74 , pp. 245-248
    • Gustafsson, J.A.1    Warner, M.2
  • 12
    • 0037501319 scopus 로고    scopus 로고
    • The estrogen receptor: a model for molecular medicine
    • Jensen E.V., and Jordan V.C. The estrogen receptor: a model for molecular medicine. Clinical Cancer Research 9 (2003) 1980-1989
    • (2003) Clinical Cancer Research , vol.9 , pp. 1980-1989
    • Jensen, E.V.1    Jordan, V.C.2
  • 13
    • 85047700175 scopus 로고    scopus 로고
    • Functional P53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-jB activation in gastric cancer cells
    • Jiang X.H., Wong B.C., Lin M.C., Zhu G.H., Kung H.F., Jiang S.H., Yang D., and Lam S.K. Functional P53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-jB activation in gastric cancer cells. Oncogene 20 (2001) 8009-8018
    • (2001) Oncogene , vol.20 , pp. 8009-8018
    • Jiang, X.H.1    Wong, B.C.2    Lin, M.C.3    Zhu, G.H.4    Kung, H.F.5    Jiang, S.H.6    Yang, D.7    Lam, S.K.8
  • 14
    • 33845929000 scopus 로고    scopus 로고
    • Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer
    • Jordan V.C., and Brodie A.M.H. Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer. Steroids 72 (2007) 7-25
    • (2007) Steroids , vol.72 , pp. 7-25
    • Jordan, V.C.1    Brodie, A.M.H.2
  • 15
    • 0036023433 scopus 로고    scopus 로고
    • Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells
    • Kiviharju T.M., Lecane P.S., Sellers R.G., and Peehl D.M. Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells. Clinical Cancer Research 8 (2002) 2666-2674
    • (2002) Clinical Cancer Research , vol.8 , pp. 2666-2674
    • Kiviharju, T.M.1    Lecane, P.S.2    Sellers, R.G.3    Peehl, D.M.4
  • 17
    • 0030939874 scopus 로고    scopus 로고
    • A potential new treatment for rheumatoid arthritis: thunder god vine
    • Lipsky P.E., and Tao X.L. A potential new treatment for rheumatoid arthritis: thunder god vine. Seminars in Arthritis and Rheumatism 5 (1997) 713-723
    • (1997) Seminars in Arthritis and Rheumatism , vol.5 , pp. 713-723
    • Lipsky, P.E.1    Tao, X.L.2
  • 18
    • 33646854369 scopus 로고    scopus 로고
    • Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation
    • Liu Q., Chen T., Chen G., Li N., Wang J., Ma P., and Cao X. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation. Biochemical and Biophysical Research Communications 345 (2006) 1122-1130
    • (2006) Biochemical and Biophysical Research Communications , vol.345 , pp. 1122-1130
    • Liu, Q.1    Chen, T.2    Chen, G.3    Li, N.4    Wang, J.5    Ma, P.6    Cao, X.7
  • 19
    • 8444220061 scopus 로고    scopus 로고
    • Triptolide inhibits transcription factor NF-kappaB and induces apoptosis of multiple myeloma cells
    • Lou Y.J., Jin J., and Wang Y.G. Triptolide inhibits transcription factor NF-kappaB and induces apoptosis of multiple myeloma cells. Leukemia Research 29 (2005) 99-105
    • (2005) Leukemia Research , vol.29 , pp. 99-105
    • Lou, Y.J.1    Jin, J.2    Wang, Y.G.3
  • 20
    • 4143087257 scopus 로고    scopus 로고
    • Histone deacetylase inhibition and estrogen signaling in human breast cancer cells
    • Margueron R., Duong V., Castet A., and Cavailles V. Histone deacetylase inhibition and estrogen signaling in human breast cancer cells. Biochemical Pharmacology 68 (2004) 1239-1246
    • (2004) Biochemical Pharmacology , vol.68 , pp. 1239-1246
    • Margueron, R.1    Duong, V.2    Castet, A.3    Cavailles, V.4
  • 21
    • 0037204724 scopus 로고    scopus 로고
    • Connections and regulation of the human estrogen receptor
    • McDonnell D.P., and Norris J.D. Connections and regulation of the human estrogen receptor. Science 296 (2002) 1642-1644
    • (2002) Science , vol.296 , pp. 1642-1644
    • McDonnell, D.P.1    Norris, J.D.2
  • 22
    • 25644455082 scopus 로고    scopus 로고
    • 2-terminal kinase 1 by decreasing phosphatidylinositol 3-kinase activity in human tumor cells
    • 2-terminal kinase 1 by decreasing phosphatidylinositol 3-kinase activity in human tumor cells. Biochemical and Biophysical Research Communications 336 (2005) 1081-1086
    • (2005) Biochemical and Biophysical Research Communications , vol.336 , pp. 1081-1086
    • Miyata, Y.1    Sato, T.2    Ito, A.3
  • 25
    • 33747466839 scopus 로고    scopus 로고
    • Structure-function relationship of estrogen receptor a and b: Impact on human health
    • Paolo A., Alessio B., and Maria M. Structure-function relationship of estrogen receptor a and b: Impact on human health. Molecular Aspects of Medicine 27 (2006) 299-402
    • (2006) Molecular Aspects of Medicine , vol.27 , pp. 299-402
    • Paolo, A.1    Alessio, B.2    Maria, M.3
  • 26
    • 0036154287 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators (SERMS) and their roles in breast cancer prevention
    • Park W.C., and Jordan V.C. Selective estrogen receptor modulators (SERMS) and their roles in breast cancer prevention. Trends in Molecular Medicine 8 (2002) 82-88
    • (2002) Trends in Molecular Medicine , vol.8 , pp. 82-88
    • Park, W.C.1    Jordan, V.C.2
  • 27
    • 0042662901 scopus 로고    scopus 로고
    • Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f
    • Qiu D., and Kao P.N. Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f. Drugs in R&D 4 (2003) 1-18
    • (2003) Drugs in R&D , vol.4 , pp. 1-18
    • Qiu, D.1    Kao, P.N.2
  • 29
    • 0036065039 scopus 로고    scopus 로고
    • Benefit of an extract of Tripterygium Wilfordii Hook F in patients with rheumatoid arthritis: a double-blind, placebo-controlled study
    • Tao X.L., Younger J., Fan F.Z., Wang B., and Lipsky P.E. Benefit of an extract of Tripterygium Wilfordii Hook F in patients with rheumatoid arthritis: a double-blind, placebo-controlled study. Arthritis & Rheumatism 46 (2002) 1735-1743
    • (2002) Arthritis & Rheumatism , vol.46 , pp. 1735-1743
    • Tao, X.L.1    Younger, J.2    Fan, F.Z.3    Wang, B.4    Lipsky, P.E.5
  • 30
    • 33846949655 scopus 로고    scopus 로고
    • Triptolide inhibits cyclooxygenase-2 and inducible nitric oxide synthase expression in human colon cancer and leukemia cells
    • Tong X., Zheng S., Jin J., Zhu L., Lou Y., and Yao H. Triptolide inhibits cyclooxygenase-2 and inducible nitric oxide synthase expression in human colon cancer and leukemia cells. Acta Biochimica et Biophysica Sinica 39 (2007) 89-95
    • (2007) Acta Biochimica et Biophysica Sinica , vol.39 , pp. 89-95
    • Tong, X.1    Zheng, S.2    Jin, J.3    Zhu, L.4    Lou, Y.5    Yao, H.6
  • 32
    • 70349762316 scopus 로고
    • Analysis of forward curative effects of 88 cases of breast cancer treated by halsted's radical operation
    • Wang W.J. Analysis of forward curative effects of 88 cases of breast cancer treated by halsted's radical operation. Journal of Linyi Medical school 10 (1988) 141-144
    • (1988) Journal of Linyi Medical school , vol.10 , pp. 141-144
    • Wang, W.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.