Dioxin silences gonadotropin expression in perinatal pups by inducing histone deacetylases: A new insight into the mechanism for the imprinting of sexual immaturity by dioxin

Journal of Biological Chemistry

Volumn 287, Issue 22, 2012, Pages 18440-18450

  Takeda, Tomoki ^a   Fujii, Misaki ^a   Taura, Junki ^a   Ishii, Yuji ^a   Yamada, Hideyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 ,3 ,7 ,8 TETRACHLORODIBENZO P DIOXINS; DEACETYLATION; DNA MICROARRAY ANALYSIS; FOLLICLE STIMULATING HORMONE; HDAC INHIBITORS; HISTONE DEACETYLASES; MATERNAL EXPOSURE; ORAL DOSE; PREGNANT RAT; TARGET GENES; VALPROIC ACID;

ACETYLATION; GENES; ORGANIC POLLUTANTS;

PROTEINS;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; GONADOTROPIN; HISTONE DEACETYLASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEACETYLATION; DNA METHYLATION; DNA MICROARRAY; ENZYME INDUCTION; FEMALE; FETUS; GENE; GENE IDENTIFICATION; GENE TARGETING; GONADOTROPIN GENE; HISTONE ACETYLATION; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; IMMATURITY; LH BETA GENE; MALE; NONHUMAN; PATHOPHYSIOLOGY; PERINATAL PERIOD; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; SEXUAL IMMATURITY; STEROIDOGENESIS;

ANIMALS; BASE SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; ENZYME INDUCTION; EPIGENESIS, GENETIC; FEMALE; GONADOTROPINS; HISTONE DEACETYLASES; MALE; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PITUITARY GLAND; PREGNANCY; RATS; RATS, WISTAR; SEXUAL MATURATION; STEROIDS; TETRACHLORODIBENZODIOXIN;

RATTUS;

EID: 84861565279     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.335158     Document Type: Article

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