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Volumn 44, Issue 6, 2010, Pages 349-362

Activin A induction of FSHβ subunit transcription requires SMAD4 in immortalized gonadotropes

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; FOLLITROPIN BETA SUBUNIT; LEPTOMYCIN B; MESSENGER RNA; SMAD4 PROTEIN; ACTIVIN; SMAD4 PROTEIN, MOUSE; UNSATURATED FATTY ACID;

EID: 77952785712     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1677/JME-09-0142     Document Type: Article
Times cited : (24)

References (45)
  • 1
    • 0029846336 scopus 로고    scopus 로고
    • Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice
    • Alarid ET, Windle JJ, Whyte DB & Mellon PL 1996 Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice. Development 122 3319-3329.
    • (1996) Development , vol.122 , pp. 3319-3329
    • Alarid, E.T.1    Windle, J.J.2    Whyte, D.B.3    Mellon, P.L.4
  • 2
    • 0025088943 scopus 로고
    • Rapid stimulatory effect of activin-A on messenger RNA encoding the follicle-stimulating hormone beta-subunit in rat pituitary cell cultures
    • Attardi B & Miklos J 1990 Rapid stimulatory effect of activin-A on messenger RNA encoding the follicle-stimulating hormone beta-subunit in rat pituitary cell cultures. Molecular Endocrinology 4 721-726. (Pubitemid 20369382)
    • (1990) Molecular Endocrinology , vol.4 , Issue.5 , pp. 721-726
    • Attardi, B.1    Miklos, J.2
  • 4
    • 0028805019 scopus 로고
    • Experimental bias in the evaluation of the cellular transient expression in DNA co-transfection experiments
    • Bergeron D, Barbeau B, Leger C & Rassart E 1995 Experimental bias in the evaluation of the cellular transient expression in DNA co-transfection experiments. Cellular and Molecular Biology Research 41 155-159.
    • (1995) Cellular and Molecular Biology Research , vol.41 , pp. 155-159
    • Bergeron, D.1    Barbeau, B.2    Leger, C.3    Rassart, E.4
  • 5
    • 1542267684 scopus 로고    scopus 로고
    • Both SMAD2 and SMAD3 mediate activin-stimulated expression of the follicle-stimulating hormone beta subunit in mouse gonadotrope cells
    • Bernard DJ 2004 Both SMAD2 and SMAD3 mediate activin-stimulated expression of the follicle-stimulating hormone beta subunit in mouse gonadotrope cells. Molecular Endocrinology 18 606-623.
    • (2004) Molecular Endocrinology , vol.18 , pp. 606-623
    • Bernard, D.J.1
  • 8
    • 0033585086 scopus 로고    scopus 로고
    • Smad4/DPC4 silencing and hyperactive ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells
    • Calonge MJ & Massague J 1999 Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells. Journal of Biological Chemistry 274 33637-33643. (Pubitemid 129511676)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.47 , pp. 33637-33643
    • Calonge, M.J.1    Massague, J.2
  • 10
    • 4444250157 scopus 로고    scopus 로고
    • Structural basis of heteromeric Smad protein assembly in TGF-beta signaling
    • DOI 10.1016/j.molcel.2004.07.016, PII S1097276504004381
    • Chacko BM, Qin BY, Tiwari A, Shi G, Lam S, Hayward LJ, De Caestecker M & Lin K 2004 Structural basis of heteromeric smad protein assembly in TGF-beta signaling. Molecular Cell 15 813-823. (Pubitemid 39194910)
    • (2004) Molecular Cell , vol.15 , Issue.5 , pp. 813-823
    • Chacko, B.M.1    Qin, B.Y.2    Tiwari, A.3    Shi, G.4    Lam, S.5    Hayward, L.J.6    De Caestecker, M.7    Lin, K.8
  • 11
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S & Gauthier JM 1998 Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO Journal 17 3091-3100.
    • (1998) EMBO Journal , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 13
    • 60149089402 scopus 로고    scopus 로고
    • Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone beta subunit transcription
    • Fortin J, Lamba P, Wang Y & Bernard DJ 2009 Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone beta subunit transcription. Molecular Human Reproduction 15 77-87.
    • (2009) Molecular Human Reproduction , vol.15 , pp. 77-87
    • Fortin, J.1    Lamba, P.2    Wang, Y.3    Bernard, D.J.4
  • 14
    • 0026515183 scopus 로고
    • Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer
    • Goyette MC, Cho K, Fasching CL, Levy DB, Kinzler KW, Paraskeva C, Vogelstein B & Stanbridge EJ 1992 Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer. Molecular and Cellular Biology 12 1387-1395.
    • (1992) Molecular and Cellular Biology , vol.12 , pp. 1387-1395
    • Goyette, M.C.1    Cho, K.2    Fasching, C.L.3    Levy, D.B.4    Kinzler, K.W.5    Paraskeva, C.6    Vogelstein, B.7    Stanbridge, E.J.8
  • 15
    • 11244344719 scopus 로고    scopus 로고
    • Senergy between activin a and gonadotropin-releasing hormone in transcriptional activation of the rat follicle-stimulating hormone-beta gene
    • DOI 10.1210/me.2003-0473
    • Gregory SJ, Lacza CT, Detz AA, Xu S, Petrillo LA & Kaiser UB 2005 Synergy between activin A and gonadotropin-releasing hormone in transcriptional activation of the rat follicle-stimulating hormone-beta gene. Molecular Endocrinology 19 237-254. (Pubitemid 40065973)
    • (2005) Molecular Endocrinology , vol.19 , Issue.1 , pp. 237-254
    • Gregory, S.J.1    Lacza, C.T.2    Detz, A.A.3    Xu, S.4    Petrillo, L.A.5    Kaiser, U.B.6
  • 16
    • 0031036095 scopus 로고    scopus 로고
    • Measure of transient transfection efficiency using beta-galactosidase protein
    • Howcroft TK, Kirshner SL & Singer DS 1997 Measure of transient transfection efficiency using beta-galactosidase protein. Analytical Biochemistry 244 22-27.
    • (1997) Analytical Biochemistry , vol.244 , pp. 22-27
    • Howcroft, T.K.1    Kirshner, S.L.2    Singer, D.S.3
  • 17
    • 0035850254 scopus 로고    scopus 로고
    • The use of a second reporter plasmid as an internal standard to normalize luciferase activity in transient transfection experiments may lead to a systematic error
    • DOI 10.1016/S0168-1656(01)00277-2, PII S0168165601002772
    • Huszar T, Mucsi I, Terebessy T, Masszi A, Adamko S, Jeney C & Rosivall L 2001 The use of a second reporter plasmid as an internal standard to normalize luciferase activity in transient transfection experiments may lead to a systematic error. Journal of Biotechnology 88 251-258. (Pubitemid 32575303)
    • (2001) Journal of Biotechnology , vol.88 , Issue.3 , pp. 251-258
    • Huszar, T.1    Mucsi, I.2    Terebessy, T.3    Masszi, A.4    Adamko, S.5    Jeney, C.6    Rosivall, L.7
  • 18
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman GJ, Nicolas FJ, Callahan JF, Harling JD, Gaster LM, Reith AD, Laping NJ & Hill CS 2002 SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Molecular Pharmacology 62 65-74.
    • (2002) Molecular Pharmacology , vol.62 , pp. 65-74
    • Inman, G.J.1    Nicolas, F.J.2    Callahan, J.F.3    Harling, J.D.4    Gaster, L.M.5    Reith, A.D.6    Laping, N.J.7    Hill, C.S.8
  • 19
    • 0014604721 scopus 로고
    • Murine sarcoma and leukemia viruses: Assay using clonal lines of contact-inhibited mouse cells
    • Jainchill JL, Aaronson SA & Todaro GJ 1969 Murine sarcoma and leukemia viruses: assay using clonal lines of contact-inhibited mouse cells. Journal of Virology 4 549-553.
    • (1969) Journal of Virology , vol.4 , pp. 549-553
    • Jainchill, J.L.1    Aaronson, S.A.2    Todaro, G.J.3
  • 21
    • 33244482566 scopus 로고    scopus 로고
    • Acute regulation of murine follicle-stimulating hormone beta subunit transcription by activin a
    • DOI 10.1677/jme.1.01961
    • Lamba P, Santos MM, Philips DP & Bernard DJ 2006 Acute regulation of murine follicle-stimulating hormone beta subunit transcription by activin A. Journal of Molecular Endocrinology 36 201-220. (Pubitemid 43273676)
    • (2006) Journal of Molecular Endocrinology , vol.36 , Issue.1 , pp. 201-220
    • Lamba, P.1    Santos, M.M.2    Philips, D.P.3    Bernard, D.J.4
  • 22
    • 67649592212 scopus 로고    scopus 로고
    • A novel role for the forkhead transcription factor FOXL2 in activin A-regulated follicle-stimulating hormone beta subunit transcription
    • Lamba P, Fortin J, Tran S, Wang Y & Bernard DJ 2009 A novel role for the forkhead transcription factor FOXL2 in activin A-regulated follicle-stimulating hormone beta subunit transcription. Molecular Endocrinology 23 1001-1013.
    • (2009) Molecular Endocrinology , vol.23 , pp. 1001-1013
    • Lamba, P.1    Fortin, J.2    Tran, S.3    Wang, Y.4    Bernard, D.J.5
  • 23
    • 33847656978 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 and activin a synergistically stimulate follicle-stimulating hormone beta subunit transcription
    • DOI 10.1677/jme.1.02196
    • Lee KB, Khivansara V, Santos MM, Lamba P, Yuen T, Sealfon SC & Bernard DJ 2007 Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone beta subunit transcription. Journal of Molecular Endocrinology 38 315-330. (Pubitemid 46351612)
    • (2007) Journal of Molecular Endocrinology , vol.38 , Issue.1-2 , pp. 315-330
    • Lee, K.B.1    Khivansara, V.2    Santos, M.M.3    Lamba, P.4    Yuen, T.5    Sealfon, S.C.6    Bernard, D.J.7
  • 24
    • 0022554075 scopus 로고
    • A homodimer of the beta-subunits of inhibin a stimulates the secretion of pituitary follicle stimulating hormone
    • Ling N, Ying SY, Ueno N, Shimasaki S, Esch F, Hotta M & Guillemin R 1986a A homodimer of the beta-subunits of inhibin A stimulates the secretion of pituitary follicle stimulating hormone. Biochemical and Biophysical Research Communications 138 1129-1137. (Pubitemid 16028517)
    • (1986) Biochemical and Biophysical Research Communications , vol.138 , Issue.3 , pp. 1129-1137
    • Ling, N.1    Ying, S.-Y.2    Uneo, N.3
  • 25
    • 0022470831 scopus 로고
    • Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin
    • Ling N, Ying SY, Ueno N, Shimasaki S, Esch F, Hotta M & Guillemin R 1986b Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin. Nature 321 779-782. (Pubitemid 16077905)
    • (1986) Nature , vol.321 , Issue.6072 , pp. 779-782
    • Ling, N.1    Ying, S.-Y.2    Ueno, N.3
  • 27
    • 0028929864 scopus 로고
    • Different phenotypes for mice deficient in either activins or activin receptor type II
    • Matzuk MM, Kumar TR & Bradley A 1995 Different phenotypes for mice deficient in either activins or activin receptor type II. Nature 374 356-360.
    • (1995) Nature , vol.374 , pp. 356-360
    • Matzuk, M.M.1    Kumar, T.R.2    Bradley, A.3
  • 28
    • 0035900731 scopus 로고    scopus 로고
    • Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability
    • DOI 10.1074/jbc.M105895200
    • Maurice D, Pierreux CE, Howell M, Wilentz RE, Owen MJ & Hill CS 2001 Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability. Journal of Biological Chemistry 276 43175-43181. (Pubitemid 37371002)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.46 , pp. 43175-43181
    • Maurice, D.1    Pierreux, C.E.2    Howell, M.3    Wilentz, R.E.4    Owen, M.J.5    Hill, C.S.6
  • 29
    • 33846426149 scopus 로고    scopus 로고
    • Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell line
    • DOI 10.1210/en.2006-0952
    • McGillivray SM, Thackray VG, Coss D & Mellon PL 2007 Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell line. Endocrinology 148 762-773. (Pubitemid 46143177)
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 762-773
    • McGillivray, S.M.1    Thackray, V.G.2    Coss, D.3    Mellon, P.L.4
  • 30
    • 33745212905 scopus 로고    scopus 로고
    • Transcription of gonadotropin beta subunit genes involves cross-talk between the transcription factors and co-regulators that mediate actions of the regulatory hormones
    • DOI 10.1016/j.mce.2006.03.024, PII S0303720706001250
    • Melamed P, Kadir MN, Wijeweera A & Seah S 2006 Transcription of gonadotropin beta subunit genes involves cross-talk between the transcription factors and co-regulators that mediate actions of the regulatory hormones. Molecular and Cellular Endocrinology 252 167-183. (Pubitemid 43914094)
    • (2006) Molecular and Cellular Endocrinology , vol.252 , Issue.1-2 , pp. 167-183
    • Melamed, P.1    Kadir, M.N.A.2    Wijeweera, A.3    Seah, S.4
  • 31
    • 0034618406 scopus 로고    scopus 로고
    • Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4
    • Moren A, Itoh S, Moustakas A, Dijke P & Heldin CH 2000 Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4. Oncogene 19 4396-4404.
    • (2000) Oncogene , vol.19 , pp. 4396-4404
    • Moren, A.1    Itoh, S.2    Moustakas, A.3    Dijke, P.4    Heldin, C.H.5
  • 32
    • 0035020036 scopus 로고    scopus 로고
    • Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model
    • DOI 10.1210/en.142.6.2284
    • Pernasetti F, Vasilyev VV, Rosenberg SB, Bailey JS, Huang HJ, Miller WL &Mellon PL 2001 Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model. Endocrinology 142 2284-2295. (Pubitemid 32473082)
    • (2001) Endocrinology , vol.142 , Issue.6 , pp. 2284-2295
    • Pernasetti, F.1    Vyacheslav, V.V.2    Rosenberg, S.B.3    Bailey, J.S.4    Huang, H.-J.5    Miller, W.L.6    Mellon, P.L.7
  • 33
    • 0034460336 scopus 로고    scopus 로고
    • Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus
    • DOI 10.1128/MCB.20.23.9041-9054.2000
    • Pierreux CE, Nicolas FJ & Hill CS 2000 Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus. Molecular and Cellular Biology 20 9041-9054. (Pubitemid 32245933)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.23 , pp. 9041-9054
    • Pierreux, C.E.1    Nicolas, F.J.2    Hill, C.S.3
  • 34
    • 84873782420 scopus 로고
    • Genetics of somatic mammalian cells. III. Long-term cultivation of euploid cells from human and animal subjects
    • Puck TT, Cieciura SJ & Robinson A 1958 Genetics of somatic mammalian cells. III. Long-term cultivation of euploid cells from human and animal subjects. Journal of Experimental Medicine 108 945-956.
    • (1958) Journal of Experimental Medicine , vol.108 , pp. 945-956
    • Puck, T.T.1    Cieciura, S.J.2    Robinson, A.3
  • 35
    • 0030837455 scopus 로고    scopus 로고
    • A structural basis for mutational inactivation of the tumour suppressor Smad4
    • DOI 10.1038/40431
    • Shi Y, Hata A, Lo RS, Massague J & Pavletich NP 1997 A structural basis formutational inactivation of the tumour suppressor Smad4. Nature 388 87-93. (Pubitemid 27283894)
    • (1997) Nature , vol.388 , Issue.6637 , pp. 87-93
    • Shi, Y.1    Hata, A.2    Lo, R.S.3    Massague, J.4    Pavletich, N.P.5
  • 36
    • 70449699603 scopus 로고    scopus 로고
    • Factors modulating expression of Renilla luciferase from control plasmids used in luciferase reporter gene assays
    • Shifera AS & Hardin JA 2010 Factors modulating expression of Renilla luciferase from control plasmids used in luciferase reporter gene assays. Analytical Biochemistry 396 167-172.
    • (2010) Analytical Biochemistry , vol.396 , pp. 167-172
    • Shifera, A.S.1    Hardin, J.A.2
  • 37
    • 0034051750 scopus 로고    scopus 로고
    • Correct evaluation of reporter assays in different cell lines by direct determination of the introduced plasmid amount
    • Siedow A, Gratchev A & Hanski C 2000 Correct evaluation of reporter assays in different cell lines by direct determination of the introduced plasmid amount. European Journal of Cell Biology 79 150-153. (Pubitemid 30119582)
    • (2000) European Journal of Cell Biology , vol.79 , Issue.2 , pp. 150-153
    • Siedow, A.1    Gratchev, A.2    Hanski, C.3
  • 38
    • 0037340049 scopus 로고    scopus 로고
    • Regulation of the rat follicle-stimulating hormone beta-subunit promoter by activin
    • DOI 10.1210/me.2002-0081
    • Suszko MI, Lo DJ, Suh H, Camper SA & Woodruff TK 2003 Regulation of the rat follicle-stimulating hormone beta-subunit promoter by activin. Molecular Endocrinology 17 318-332. (Pubitemid 36315627)
    • (2003) Molecular Endocrinology , vol.17 , Issue.3 , pp. 318-332
    • Suszko, M.I.1    Lo, D.J.2    Suh, H.3    Camper, S.A.4    Woodruff, T.K.5
  • 39
    • 22444435108 scopus 로고    scopus 로고
    • Smad3 mediates activin-induced transcription of follicle-stimulating hormone beta-subunit gene
    • DOI 10.1210/me.2004-0475
    • Suszko MI, Balkin DM, Chen Y & Woodruff TK 2005 Smad3 mediates activin-induced transcription of follicle-stimulating hormone beta-subunit gene. Molecular Endocrinology 19 1849-1858. (Pubitemid 41007896)
    • (2005) Molecular Endocrinology , vol.19 , Issue.7 , pp. 1849-1858
    • Suszko, M.I.1    Balkin, D.M.2    Chen, Y.3    Woodruff, T.K.4
  • 40
    • 33747846303 scopus 로고    scopus 로고
    • Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone beta-subunit gene expression at the level of the gonadotrope
    • Thackray VG, McGillivray SM & Mellon PL 2006 Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone beta-subunit gene expression at the level of the gonadotrope. Molecular Endocrinology 20 2062-2079.
    • (2006) Molecular Endocrinology , vol.20 , pp. 2062-2079
    • Thackray, V.G.1    McGillivray, S.M.2    Mellon, P.L.3
  • 42
    • 0022907945 scopus 로고
    • Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid
    • Vale W, Rivier J, Vaughan J, McClintock R, Corrigan A, Woo W, Karr D & Spiess J 1986 Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid. Nature 321 776-779. (Pubitemid 16077904)
    • (1986) Nature , vol.321 , Issue.6072 , pp. 776-779
    • Vale, W.1    Rivier, J.2    Vaughan, J.3
  • 43
    • 0034252221 scopus 로고    scopus 로고
    • Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal
    • Watanabe M, Masuyama N, Fukuda M & Nishida E 2000 Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal. EMBO Reports 1 176-182.
    • (2000) EMBO Reports , vol.1 , pp. 176-182
    • Watanabe, M.1    Masuyama, N.2    Fukuda, M.3    Nishida, E.4
  • 44
    • 0028948078 scopus 로고
    • Transcriptional activation of the follicle-stimulating hormone beta-subunit gene by activin
    • Weiss J, Guendner MJ, Halvorson LM & Jameson JL 1995 Transcriptional activation of the follicle-stimulating hormone beta-subunit gene by activin. Endocrinology 136 1885-1891.
    • (1995) Endocrinology , vol.136 , pp. 1885-1891
    • Weiss, J.1    Guendner, M.J.2    Halvorson, L.M.3    Jameson, J.L.4
  • 45
    • 0030963943 scopus 로고    scopus 로고
    • DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells
    • de Winter JP, Roelen BA, ten Dijke P, van der Burg B & van den Eijnden-van Raaij AJ 1997 DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells. Oncogene 14 1891-1899.
    • (1997) Oncogene , vol.14 , pp. 1891-1899
    • De Winter, J.P.1    Roelen, B.A.2    Ten Dijke, P.3    Van Der Burg, B.4    Van Den Eijnden-van Raaij, A.J.5


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