-
1
-
-
12944288132
-
siRNA mediated inhibition of MMP-1 reduces invasive potential of a human chondrosarcoma cell line
-
Jiang X, Dutton CM, Qi WN, et al. siRNA mediated inhibition of MMP-1 reduces invasive potential of a human chondrosarcoma cell line. J Cell Physiol. 2005; 202: 723-30.
-
(2005)
J Cell Physiol
, vol.202
, pp. 723-730
-
-
Jiang, X.1
Dutton, C.M.2
Qi, W.N.3
-
2
-
-
17644387578
-
Matrix metalloproteinases target protease-activated receptors on the tumour cell surface
-
Pei D. Matrix metalloproteinases target protease-activated receptors on the tumour cell surface. Cancer Cell. 2005; 7: 207-8.
-
(2005)
Cancer Cell
, vol.7
, pp. 207-208
-
-
Pei, D.1
-
3
-
-
0027199386
-
Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology
-
Polette M, Clavel C, Cockett M, et al. Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology. Invasion Metast. 1993; 13: 31-7.
-
(1993)
Invasion Metast
, vol.13
, pp. 31-37
-
-
Polette, M.1
Clavel, C.2
Cockett, M.3
-
4
-
-
0035286224
-
Expression of matrix metalloproteinases 1, 2, 9 and their tissue inhibitors in stage II non-small cell lung cancer: implications for MMP inhibition therapy
-
Pritchard SC, Nicolson MC, Lloret C, et al. Expression of matrix metalloproteinases 1, 2, 9 and their tissue inhibitors in stage II non-small cell lung cancer: implications for MMP inhibition therapy. Oncol Rep. 2001; 8: 421-4.
-
(2001)
Oncol Rep
, vol.8
, pp. 421-424
-
-
Pritchard, S.C.1
Nicolson, M.C.2
Lloret, C.3
-
5
-
-
34249807326
-
A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma
-
Vachani A, Nebozhyn M, Singhal S, et al. A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma. Clin Cancer Res. 2007; 13: 2905-15.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2905-2915
-
-
Vachani, A.1
Nebozhyn, M.2
Singhal, S.3
-
6
-
-
0032854578
-
Specialized surface protrusions of invasive cells, invadopodia and lamellipodia, have differential MT1-MMP, MMP-2, and TIMP-2 localization
-
Chen WT, Wang JY. Specialized surface protrusions of invasive cells, invadopodia and lamellipodia, have differential MT1-MMP, MMP-2, and TIMP-2 localization. Ann N Y Acad Sci. 1999; 878: 361-71.
-
(1999)
Ann N Y Acad Sci
, vol.878
, pp. 361-371
-
-
Chen, W.T.1
Wang, J.Y.2
-
7
-
-
33845502729
-
Understanding effects of matrix protease and matrix organization on directional persistence and translational speed in three-dimensional cell migration
-
Zaman MH, Matsudaira P, Lauffenburger DA. Understanding effects of matrix protease and matrix organization on directional persistence and translational speed in three-dimensional cell migration. Ann Biomed Eng. 2007; 35: 91-100.
-
(2007)
Ann Biomed Eng
, vol.35
, pp. 91-100
-
-
Zaman, M.H.1
Matsudaira, P.2
Lauffenburger, D.A.3
-
8
-
-
33746593689
-
Migration of tumour cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis. [erratum appears in Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13897]
-
Zaman MH, Trapani LM, Sieminski AL, et al. Migration of tumour cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis. [erratum appears in Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13897]. Proc Natl Acad Sci U S A. 2006; 103: 10889-94.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10889-10894
-
-
Zaman, M.H.1
Trapani, L.M.2
Sieminski, A.L.3
-
9
-
-
0242384076
-
Inhibition of MMP-1 expression by antisense RNA decreases invasiveness of human chondrosarcoma
-
Jiang X, Dutton CM, Qi W, et al. Inhibition of MMP-1 expression by antisense RNA decreases invasiveness of human chondrosarcoma. J Orthop Res. 2003; 21: 1063-70.
-
(2003)
J Orthop Res
, vol.21
, pp. 1063-1070
-
-
Jiang, X.1
Dutton, C.M.2
Qi, W.3
-
10
-
-
27644507899
-
RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasion
-
Yuan J, Dutton CM, Scully SP. RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasion. J Orthop Res. 2005; 23: 1467-74.
-
(2005)
J Orthop Res
, vol.23
, pp. 1467-1474
-
-
Yuan, J.1
Dutton, C.M.2
Scully, S.P.3
-
11
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: trials and tribulations
-
Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science. 2002; 295: 2387-92.
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
12
-
-
0036716282
-
Strategies for MMP inhibition in cancer: innovations for the post-trial era
-
Overall CM, Lopez-Otin C. Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nat Rev Cancer. 2002; 2: 657-72.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 657-672
-
-
Overall, C.M.1
Lopez-Otin, C.2
-
14
-
-
33646584823
-
Recent advances in MMP inhibitor design
-
Fisher JF, Mobashery S. Recent advances in MMP inhibitor design. Cancer Metast Rev. 2006; 25: 115-36.
-
(2006)
Cancer Metast Rev
, vol.25
, pp. 115-136
-
-
Fisher, J.F.1
Mobashery, S.2
-
15
-
-
62449314690
-
Dynamic imaging of cancer invasion and metastasis: principles and preclinical applications
-
Friedl P. Dynamic imaging of cancer invasion and metastasis: principles and preclinical applications. Clin Exp Metast. 2009; 26: 269-71.
-
(2009)
Clin Exp Metast
, vol.26
, pp. 269-271
-
-
Friedl, P.1
-
16
-
-
68549130679
-
Proteolytic interstitial cell migration: a five-step process
-
Friedl P, Wolf K. Proteolytic interstitial cell migration: a five-step process. Cancer Metast Rev. 2009; 28: 129-35.
-
(2009)
Cancer Metast Rev
, vol.28
, pp. 129-135
-
-
Friedl, P.1
Wolf, K.2
-
17
-
-
0038049137
-
Tumour-cell invasion and migration: diversity and escape mechanisms
-
Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer. 2003; 3: 362-74.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
18
-
-
15244351837
-
Functional imaging of pericellular proteolysis in cancer cell invasion
-
Wolf K, Friedl P. Functional imaging of pericellular proteolysis in cancer cell invasion. Biochimie. 2005; 87: 315-20.
-
(2005)
Biochimie
, vol.87
, pp. 315-320
-
-
Wolf, K.1
Friedl, P.2
-
19
-
-
62449216585
-
Mapping proteolytic cancer cell-extracellular matrix interfaces
-
Wolf K, Friedl P. Mapping proteolytic cancer cell-extracellular matrix interfaces. Clin Exp Metast. 2009, 26: 289-98.
-
(2009)
Clin Exp Metast
, vol.26
, pp. 289-298
-
-
Wolf, K.1
Friedl, P.2
-
20
-
-
34547569807
-
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
-
Wolf K, Wu YI, Liu Y, et al. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol. 2007; 9: 893-904.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 893-904
-
-
Wolf, K.1
Wu, Y.I.2
Liu, Y.3
-
21
-
-
0642306909
-
Are prenyl groups on proteins sticky fingers or greasy handles?
-
Magee AI, Seabra MC. Are prenyl groups on proteins sticky fingers or greasy handles?Biochem J. 2003; 376: e3-4.
-
(2003)
Biochem J
, vol.376
-
-
Magee, A.I.1
Seabra, M.C.2
-
22
-
-
0035937112
-
Isoprenylcysteine carboxyl methyltransferase deficiency in mice
-
Bergo MO, Leung GK, Ambroziak P, et al. Isoprenylcysteine carboxyl methyltransferase deficiency in mice. J Biol Chem. 2001; 276: 5841-5.
-
(2001)
J Biol Chem
, vol.276
, pp. 5841-5845
-
-
Bergo, M.O.1
Leung, G.K.2
Ambroziak, P.3
-
23
-
-
0029966304
-
Protein prenyltransferases
-
Casey PJ, Seabra MC. Protein prenyltransferases. J Biol Chem. 1996; 271: 5289-92.
-
(1996)
J Biol Chem
, vol.271
, pp. 5289-5292
-
-
Casey, P.J.1
Seabra, M.C.2
-
24
-
-
0025819073
-
Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit
-
Seabra MC, Reiss Y, Casey PJ, et al. Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit. Cell. 1991; 65: 429-34.
-
(1991)
Cell
, vol.65
, pp. 429-434
-
-
Seabra, M.C.1
Reiss, Y.2
Casey, P.J.3
-
25
-
-
33644864788
-
Compartmentalized Ras/MAPK signaling
-
Mor A, Philips MR. Compartmentalized Ras/MAPK signaling. Annu Rev Immunol. 2006; 24: 771-800.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 771-800
-
-
Mor, A.1
Philips, M.R.2
-
26
-
-
33646005781
-
Emerging anti-cancer molecular mechanisms of aminobisphosphonates
-
Caraglia M, Santini D, Marra M, et al. Emerging anti-cancer molecular mechanisms of aminobisphosphonates. Endocr Relat Cancer. 2006; 13: 7-26.
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 7-26
-
-
Caraglia, M.1
Santini, D.2
Marra, M.3
-
27
-
-
34347369084
-
Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets
-
Konstantinopoulos PA, Karamouzis MV, Papavassiliou AG. Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets. Nat Rev Drug Discov. 2007; 6: 541-55.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 541-555
-
-
Konstantinopoulos, P.A.1
Karamouzis, M.V.2
Papavassiliou, A.G.3
-
28
-
-
33845944650
-
Multilevel modulation of the mevalonate and protein-prenylation circuitries as a novel strategy for anticancer therapy
-
Konstantinopoulos PA, Papavassiliou AG. Multilevel modulation of the mevalonate and protein-prenylation circuitries as a novel strategy for anticancer therapy. Trends Pharmacol Sci. 2007; 28: 6-13.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 6-13
-
-
Konstantinopoulos, P.A.1
Papavassiliou, A.G.2
-
29
-
-
35348839555
-
Zoledronic acid-a multiplicity of anti-cancer action
-
Yuasa T, Kimura S, Ashihara E, et al. Zoledronic acid-a multiplicity of anti-cancer action. Curr Med Chem. 2007; 14: 2126-35.
-
(2007)
Curr Med Chem
, vol.14
, pp. 2126-2135
-
-
Yuasa, T.1
Kimura, S.2
Ashihara, E.3
-
30
-
-
0034062298
-
Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance
-
Bialek-Wyrzykowska U, Bauer BE, Wagner W, et al. Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance. Mol Microbiol. 2000; 35: 1295-311.
-
(2000)
Mol Microbiol
, vol.35
, pp. 1295-1311
-
-
Bialek-Wyrzykowska, U.1
Bauer, B.E.2
Wagner, W.3
-
31
-
-
0034525706
-
Chemopreventive efficacy of promising farnesyltransferase inhibitors
-
Lantry LE, Zhang Z, Crist KA, et al. Chemopreventive efficacy of promising farnesyltransferase inhibitors. Exp Lung Res. 2000; 26: 773-90.
-
(2000)
Exp Lung Res
, vol.26
, pp. 773-790
-
-
Lantry, L.E.1
Zhang, Z.2
Crist, K.A.3
-
32
-
-
71949085193
-
Fas-induced apoptosis of renal cell carcinoma is mediated by apoptosis signal-regulating kinase 1 via mitochondrial damage-dependent caspase-8 activation
-
Hassan M, Feyen O, Grinstein E. Fas-induced apoptosis of renal cell carcinoma is mediated by apoptosis signal-regulating kinase 1 via mitochondrial damage-dependent caspase-8 activation. Cell Oncol. 2009; 31: 437-56.
-
(2009)
Cell Oncol
, vol.31
, pp. 437-456
-
-
Hassan, M.1
Feyen, O.2
Grinstein, E.3
-
33
-
-
34447529115
-
Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors
-
Clark MK, Scott SA, Wojtkowiak J, et al. Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors. J Med Chem. 2007; 50: 3274-82.
-
(2007)
J Med Chem
, vol.50
, pp. 3274-3282
-
-
Clark, M.K.1
Scott, S.A.2
Wojtkowiak, J.3
-
34
-
-
8644219632
-
Clinical activity of farnesyl transferase inhibitors in hematologic malignancies: possible mechanisms of action
-
Jabbour E, Kantarjian H, Cortes J. Clinical activity of farnesyl transferase inhibitors in hematologic malignancies: possible mechanisms of action. Leuk Lymphoma. 2004; 45: 2187-95.
-
(2004)
Leuk Lymphoma
, vol.45
, pp. 2187-2195
-
-
Jabbour, E.1
Kantarjian, H.2
Cortes, J.3
-
35
-
-
0030693938
-
Anticancer activity of farnesyltransferase and geranylgeranyltransferase I inhibitors: prospects for drug development
-
Sebti SM, Hamilton AD. Anticancer activity of farnesyltransferase and geranylgeranyltransferase I inhibitors: prospects for drug development. Expert Opin Investig Drugs. 1997; 6: 1711-4.
-
(1997)
Expert Opin Investig Drugs
, vol.6
, pp. 1711-1714
-
-
Sebti, S.M.1
Hamilton, A.D.2
-
36
-
-
47349089381
-
Farnesyltransferase inhibitors: a detailed chemical view on an elusive biological problem
-
Sousa SF, Fernandes PA, Ramos MJ. Farnesyltransferase inhibitors: a detailed chemical view on an elusive biological problem. Curr Med Chem. 2008; 15: 1478-92.
-
(2008)
Curr Med Chem
, vol.15
, pp. 1478-1492
-
-
Sousa, S.F.1
Fernandes, P.A.2
Ramos, M.J.3
-
37
-
-
18344394166
-
Post-prenylation-processing enzymes as new targets in oncogenesis
-
Winter-Vann AM, Casey PJ. Post-prenylation-processing enzymes as new targets in oncogenesis. Nat Rev Cancer. 2005; 5: 405-12.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 405-412
-
-
Winter-Vann, A.M.1
Casey, P.J.2
-
38
-
-
34848885516
-
Protein isoprenylation regulates secretion of matrix metalloproteinase 1 from rheumatoid synovial fibroblasts: effects of statins and farnesyl and geranylgeranyl transferase inhibitors
-
erratum appears in Arthritis Rheum. 2007 Oct;56(10):3510 Note: Al-Mussawir, Hayfez [corrected to Al-Mussawir, Hayf E
-
Abeles AM, Marjanovic N, Park J, et al. Protein isoprenylation regulates secretion of matrix metalloproteinase 1 from rheumatoid synovial fibroblasts: effects of statins and farnesyl and geranylgeranyl transferase inhibitors. [erratum appears in Arthritis Rheum. 2007 Oct;56(10):3510 Note: Al-Mussawir, Hayfez [corrected to Al-Mussawir, Hayf E]]. Arthritis Rheumat. 2007; 56: 2840-53.
-
(2007)
Arthritis Rheumat
, vol.56
, pp. 2840-2853
-
-
Abeles, A.M.1
Marjanovic, N.2
Park, J.3
-
39
-
-
21444445440
-
Statins cause intracellular accumulation of amyloid precursor protein, beta-secretase-cleaved fragments, and amyloid beta-peptide via an isoprenoid-dependent mechanism
-
Cole SL, Grudzien A, Manhart IO, et al. Statins cause intracellular accumulation of amyloid precursor protein, beta-secretase-cleaved fragments, and amyloid beta-peptide via an isoprenoid-dependent mechanism. J Biol Chem. 2005; 280: 18755-70.
-
(2005)
J Biol Chem
, vol.280
, pp. 18755-18770
-
-
Cole, S.L.1
Grudzien, A.2
Manhart, I.O.3
-
40
-
-
0036732940
-
Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi
-
Michaelson D, Ahearn I, Bergo M, et al. Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi. Mol Biol Cell. 2002; 13: 3294-302.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 3294-3302
-
-
Michaelson, D.1
Ahearn, I.2
Bergo, M.3
-
41
-
-
20844442306
-
Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor
-
Modiano N, Lu YE, Cresswell P. Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor. Proc Natl Acad Sci U S A. 2005; 102: 8680-5.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8680-8685
-
-
Modiano, N.1
Lu, Y.E.2
Cresswell, P.3
-
42
-
-
0035070299
-
Targeting proteins to membranes, using signal sequences for lipid modifications
-
Stickney JT, Booden MA, Buss JE. Targeting proteins to membranes, using signal sequences for lipid modifications. Methods Enzymol. 2001; 332: 64-77.
-
(2001)
Methods Enzymol
, vol.332
, pp. 64-77
-
-
Stickney, J.T.1
Booden, M.A.2
Buss, J.E.3
-
43
-
-
50849085178
-
Extracellular matrix rigidity promotes invadopodia activity
-
Alexander NR, Branch KM, Parekh A, et al. Extracellular matrix rigidity promotes invadopodia activity. Curr Biol. 2008; 18: 1295-9.
-
(2008)
Curr Biol
, vol.18
, pp. 1295-1299
-
-
Alexander, N.R.1
Branch, K.M.2
Parekh, A.3
-
44
-
-
44149106941
-
A new role for contacting in invadopodia: regulation of protease secretion
-
Clark ES, Weaver AM. A new role for contacting in invadopodia: regulation of protease secretion. Eur J Cell Biol. 2008; 87: 581-90.
-
(2008)
Eur J Cell Biol
, vol.87
, pp. 581-590
-
-
Clark, E.S.1
Weaver, A.M.2
-
45
-
-
34249320529
-
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia
-
Clark ES, Whigham AS, Yarbrough WG, et al. Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. Cancer Res. 2007; 67: 4227-35.
-
(2007)
Cancer Res
, vol.67
, pp. 4227-4235
-
-
Clark, E.S.1
Whigham, A.S.2
Yarbrough, W.G.3
-
46
-
-
33744947824
-
Protein farnesyltransferase: flexible docking studies on inhibitors using computational modeling
-
Guida WC, Hamilton AD, Crotty JW, et al. Protein farnesyltransferase: flexible docking studies on inhibitors using computational modeling. J Comp-Aided Molec Design. 2005; 19: 871-85.
-
(2005)
J Comp-Aided Molec Design
, vol.19
, pp. 871-885
-
-
Guida, W.C.1
Hamilton, A.D.2
Crotty, J.W.3
-
47
-
-
0037426578
-
Membrane-type 1 matrix metalloproteinase: a key enzyme for tumour invasion
-
Seiki M. Membrane-type 1 matrix metalloproteinase: a key enzyme for tumour invasion. Cancer Lett. 2003; 194: 1-11.
-
(2003)
Cancer Lett
, vol.194
, pp. 1-11
-
-
Seiki, M.1
-
48
-
-
0038148278
-
In situ zymography: a molecular pathology technique to localize endogenous protease activity in tissue sections
-
Yan SJ, Blomme EA. In situ zymography: a molecular pathology technique to localize endogenous protease activity in tissue sections. Vet Pathol. 2003; 40: 227-36.
-
(2003)
Vet Pathol
, vol.40
, pp. 227-236
-
-
Yan, S.J.1
Blomme, E.A.2
-
49
-
-
0028567973
-
Characterization of the peptide substrate specificities of interstitial collagenase and 92-kDa gelatinase. Implications for substrate optimization
-
McGeehan GM, Bickett DM, Green M, et al. Characterization of the peptide substrate specificities of interstitial collagenase and 92-kDa gelatinase. Implications for substrate optimization. J Biol Chem. 1994; 269: 32814-20.
-
(1994)
J Biol Chem
, vol.269
, pp. 32814-32820
-
-
McGeehan, G.M.1
Bickett, D.M.2
Green, M.3
-
50
-
-
27644507899
-
RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasion
-
Yuan J, Dutton CM, Scully SP. RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasion. J Orthop Res. 2005; 23: 1467-74.
-
(2005)
J Orthop Res
, vol.23
, pp. 1467-1474
-
-
Yuan, J.1
Dutton, C.M.2
Scully, S.P.3
-
51
-
-
12944288132
-
siRNA mediated inhibition of MMP-1 reduces invasive potential of a human chondrosarcoma cell line
-
Jiang X, Dutton CM, Qi WN, et al. siRNA mediated inhibition of MMP-1 reduces invasive potential of a human chondrosarcoma cell line. J Cell Physiol. 2005; 202: 723-30.
-
(2005)
J Cell Physiol
, vol.202
, pp. 723-730
-
-
Jiang, X.1
Dutton, C.M.2
Qi, W.N.3
-
52
-
-
8444232767
-
Absence of a correlation between the presence of a single nucleotide polymorphism in the matrix metalloproteinase 1 promoter and outcome in patients of chondrosarcoma
-
Fong YC, Dutton CM, Cha SS, et al. Absence of a correlation between the presence of a single nucleotide polymorphism in the matrix metalloproteinase 1 promoter and outcome in patients of chondrosarcoma. Clin Cancer Res. 2004; 10: 7329-34.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7329-7334
-
-
Fong, Y.C.1
Dutton, C.M.2
Cha, S.S.3
-
53
-
-
0242384076
-
Inhibition of MMP-1 expression by antisense RNA decreases invasiveness of human chondrosarcoma
-
Jiang X, Dutton CM, Qi W, et al. Inhibition of MMP-1 expression by antisense RNA decreases invasiveness of human chondrosarcoma. J Orthop Res. 2003; 21: 1063-70.
-
(2003)
J Orthop Res
, vol.21
, pp. 1063-1070
-
-
Jiang, X.1
Dutton, C.M.2
Qi, W.3
-
54
-
-
0034218946
-
Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma
-
Scully SP, Berend KR, Toth A, et al. Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma. Clin Orthop Relat Res. 2000: 291-303.
-
Clin Orthop Relat Res
, vol.2000
, pp. 291-303
-
-
Scully, S.P.1
Berend, K.R.2
Toth, A.3
-
55
-
-
0033162286
-
Collagenase specificity in chondrosarcoma metastasis
-
Scully SP, Berend KR, Qi WN, et al. Collagenase specificity in chondrosarcoma metastasis. Braz J Med Biol Res. 1999; 32: 885-9.
-
(1999)
Braz J Med Biol Res
, vol.32
, pp. 885-889
-
-
Scully, S.P.1
Berend, K.R.2
Qi, W.N.3
-
56
-
-
0031909615
-
Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma
-
Berend KR, Toth AP, Harrelson JM, et al. Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma. J Bone Joint Surg Am. 1998; 80: 11-7.
-
(1998)
J Bone Joint Surg Am
, vol.80
, pp. 11-17
-
-
Berend, K.R.1
Toth, A.P.2
Harrelson, J.M.3
-
57
-
-
35348855017
-
Type I collagen-induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells
-
Kim IY, Jeong SJ, Kim ES, et al. Type I collagen-induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells. J Biochem Mol Biol. 2007; 40: 825-31.
-
(2007)
J Biochem Mol Biol
, vol.40
, pp. 825-831
-
-
Kim, I.Y.1
Jeong, S.J.2
Kim, E.S.3
-
58
-
-
33748489508
-
H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kappaB: an implication for invasive phenotype in rat liver epithelial cells
-
Lee KW, Kim MS, Kang NJ, et al. H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kappaB: an implication for invasive phenotype in rat liver epithelial cells. Int J Cancer. 2006; 119: 1767-75.
-
(2006)
Int J Cancer
, vol.119
, pp. 1767-1775
-
-
Lee, K.W.1
Kim, M.S.2
Kang, N.J.3
-
59
-
-
0029023145
-
Ras CAAX peptidomimetic FTI 276 selectively blocks tumour growth in nude mice of a human lung carcinoma with K-Ras mutation and p53 deletion
-
Sun J, Qian Y, Hamilton AD, et al. Ras CAAX peptidomimetic FTI 276 selectively blocks tumour growth in nude mice of a human lung carcinoma with K-Ras mutation and p53 deletion. Cancer Res. 1995; 55: 4243-7.
-
(1995)
Cancer Res
, vol.55
, pp. 4243-4247
-
-
Sun, J.1
Qian, Y.2
Hamilton, A.D.3
-
60
-
-
0028973293
-
Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes
-
Lerner EC, Qian Y, Blaskovich MA, et al. Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes. J Biol Chem. 1995; 270: 26802-6.
-
(1995)
J Biol Chem
, vol.270
, pp. 26802-26806
-
-
Lerner, E.C.1
Qian, Y.2
Blaskovich, M.A.3
-
61
-
-
67649380732
-
Simvastatin and lovastatin inhibit breast cell invasion induced by H-Ras
-
Kang S, Kim ES, Moon A. Simvastatin and lovastatin inhibit breast cell invasion induced by H-Ras. Oncol Rep. 2009; 21: 1317-22.
-
(2009)
Oncol Rep
, vol.21
, pp. 1317-1322
-
-
Kang, S.1
Kim, E.S.2
Moon, A.3
-
62
-
-
0033959438
-
Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
-
Lantry LE, Zhang Z, Yao R, et al. Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis. 2000; 21: 113-6.
-
(2000)
Carcinogenesis
, vol.21
, pp. 113-116
-
-
Lantry, L.E.1
Zhang, Z.2
Yao, R.3
-
63
-
-
0034284027
-
Targeting the Ras signaling pathway: a rational, mechanism-based treatment for hematologic malignancies?
-
Reuter CW, Morgan MA, Bergmann L. Targeting the Ras signaling pathway: a rational, mechanism-based treatment for hematologic malignancies?Blood. 2000; 96: 1655-69.
-
(2000)
Blood
, vol.96
, pp. 1655-1669
-
-
Reuter, C.W.1
Morgan, M.A.2
Bergmann, L.3
|