H-Ras selectively up-regulates MMP-9 and COX-2 through activation of EKK1/2 and NF-κB: An implication for invasive phenotype in rat liver epithelial cells

International Journal of Cancer

Volumn 119, Issue 8, 2006, Pages 1767-1775

  Lee, Ki Won ^a   Kim, Mi Sung ^a,b   Kang, Nam Joo ^a   Kim, Do Hee ^a   Surh, Young Joon ^a   Lee, Hyong Joo ^a   Moon, Aree ^b  

^a Seoul National University   (South Korea)

^b Duksung Women's University   (South Korea)

Author keywords

COX 2; ERK; H Ras; Invasion; MMP 9; NF B; Rat liver epithelial cells

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIN ANTIBODY; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CAFFEIC ACID PHENETHYL ESTER; CYCLOOXYGENASE 2; GELATINASE B; ILOMASTAT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOMYCIN C; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; ENZYME REGULATION; EPITHELIUM CELL; LIVER; LIVER CARCINOGENESIS; MALIGNANT TRANSFORMATION; NONHUMAN; ONCOGENE H RAS; PHENOTYPE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CYCLOOXYGENASE 2; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; ONCOGENE PROTEIN P21(RAS); PHENOTYPE; RATS; UP-REGULATION;

EID: 33748489508     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22056     Document Type: Article

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