Loss of p16ink4a function rescues cellular senescence induced by telomere dysfunction

International Journal of Molecular Sciences

Volumn 13, Issue 5, 2012, Pages 5866-5877

  Zhang, Xiufeng ^a   Wu, Xiaoming ^a   Tang, Wenru ^a   Luo, Ying ^a  

^a KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

P16ink4a; Telomere dysfunction; Werner Syndrome

Indexed keywords

CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DOXORUBICIN; GAMMA HISTONE H2AX; HISTONE H2AX; PROTEIN P53; TELOMERIC REPEAT BINDING FACTOR 2; UNCLASSIFIED DRUG; WERNER SYNDROME PROTEIN; CDKN2A PROTEIN, MOUSE; RECQ HELICASE; TRF2 PROTEIN, MOUSE; WRN PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL AGING; CELL CYCLE REGULATION; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; FIBROBLAST; GENE EXPRESSION REGULATION; GENOMIC INSTABILITY; GROWTH CURVE; GROWTH RATE; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TELOMERE DYSFUNCTION; UPREGULATION; WERNER SYNDROME; WILD TYPE; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENE TARGETING; GENETICS; METABOLISM; TELOMERE;

MUS;

ANIMALS; CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA DAMAGE; DOXORUBICIN; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCK-IN TECHNIQUES; MICE; RECQ HELICASES; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84861538051     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13055866     Document Type: Article

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