The acrylamide problem: A plant and agronomic science issue

Journal of Experimental Botany

Volumn 63, Issue 8, 2012, Pages 2841-2851

  Halford, Nigel G ^a   Curtis, Tanya Y ^a   Muttucumaru, Nira ^a   Postles, Jennifer ^a   Elmore, J Stephen ^b   Mottram, Donald S ^b  

^a ROTHAMSTED RESEARCH   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

Author keywords

Amino acids; Asparagine; Cereals; Crop quality; Food safety; Maillard reaction; Potato; Rye; Sugars; Wheat

Indexed keywords

ACRYLAMIDE;

AGRICULTURE; CHEMISTRY; GENETIC ENGINEERING; GENETICS; GLYCATION; PLANT; REVIEW; TRANSGENIC PLANT;

ACRYLAMIDE; AGRICULTURE; GENETIC ENGINEERING; MAILLARD REACTION; PLANTS; PLANTS, GENETICALLY MODIFIED;

SECALE CEREALE; SOLANUM TUBEROSUM; TRITICUM AESTIVUM;

EID: 84861386197     PISSN: 00220957     EISSN: 14602431     Source Type: Journal    
DOI: 10.1093/jxb/ers011     Document Type: Review

References (56)

1. Amrein TM, Bachmann S, Noti A, et al. 2003. Potential of acrylamide formation, sugars, and free asparagine in potatoes: a comparison of cultivars and farming systems. Journal of Agricultural and Food Chemistry 51, 5556-5560.
2. Baena-González E, Rolland F, Thevelein JM, Sheen J. 2007. A central integrator of transcription networks in plant stress and energy signalling. Nature 448, 938-942. (Pubitemid 47312777)
3. Becalski A, Lau BP-Y, Lewis D, Seaman SW, Hayward S, Sahagian M, Ramesh M, Leclerc Y. 2004. Acrylamide in French fries: influence of free amino acids and sugars. Journal of Agricultural and Food Chemistry 52, 3801-3806.
4. Bhaskar PB, Wu L, Bethke PC, Vaillancourt B, Jansky SH, Busse JS, Buell R, Hamernik AJ, Jiang J. 2010. Suppression of the vacuolar invertase gene prevents cold-induced sweetening in potato. Plant Physiology 154, 939-948.
5. Byrne EH, Prosser I, Muttucumaru N, Curtis TY, Wingler A, Powers S, Halford NG. 2012. Manipulation of GCN2 in transgenic wheat has profound effects on free amino acid concentration and gene expression. Plant Biotechnology Journal doi: 10.1111/j.1467-7652.2011.00665.x.
6. Claus A, Weisz GM, Schieber A, Carle R. 2006a. Pyrolytic acrylamide formation from purified wheat gluten and gluten-supplemented wheat bread rolls. Molecular Nutrition and Food Research 50, 87-93. (Pubitemid 43155099)
7. Claus A, Schreiter P, Weber A, Graeff S, Herrmann W, Claupein W, Schieber A, Carle R. 2006b. Influence of agronomic factors and extraction rate on the acrylamide contents in yeastleavened breads. Journal of Agricultural and Food Chemistry 54, 8968-8976. (Pubitemid 44797551)
8. Curtis TY, Muttucumaru N, Shewry PR, Parry MA, Powers SJ, Elmore JS, Mottram DS, Hook S, Halford NG. 2009. Evidence for genetic and environmental effects on free amino acid levels in wheat grain: implications for acrylamide formation during processing. Journal of Agricultural and Food Chemistry 57, 1013-1021.
9. Curtis TY, Powers SJ, Balagiannis D, Elmore JS, Mottram DS, Parry MAJ, Raksegi M, Bedo Z, Shewry PR, Halford NG. 2010. Free amino acids and sugars in rye grain: implications for acrylamide formation. Journal of Agricultural and Food Chemistry 58, 1959-1969.
10. De Wilde T, De Meulenaer B, Mestdagh F, et al. 2006. Influence of fertilization on acrylamide formation during frying of potatoes harvested in 2003. Journal of Agricultural and Food Chemistry 54, 404-408.
11. De Vleeschouwer K, Van der Plancken I, Van Loey A, Henndrickx ME. 2009. Role of precursors on the kinetics of acrylamide formation and elimination under low moisture conditions using a multiresponse approach-Part I: effect of the type of sugar. Food Chemistry 114, 116-126.
12. Elmore JS, Mottram DS, Muttucumaru N, Dodson AT, Parry MAJ, Halford NG. 2007. Changes in free amino acids and sugars in potatoes due to sulfate fertilization and the effect on acrylamide formation. Journal of Agricultural and Food Chemistry 55, 5363-5366. (Pubitemid 47056099)
13. Elmore JS, Parker JK, Halford NG, Muttucumaru N, Mottram DS. 2008. Effects of plant sulphur nutrition on acrylamide and aroma compounds in cooked wheat. Journal of Agricultural and Food Chemistry 56, 6173-6179.
14. Elmore JS, Dodson AT, Briddon A, Halford NG, Mottram DS. 2010a. The effects of storage on the formation of aroma and acrylamide in heated potato. In: DS Mottram, AJ Taylor, eds, Controlling Maillard Pathways to Generate Flavors. Washington, DC: American Chemical Society, pp 95-109.
15. Elmore JS, Dodson AT, Muttucumaru N, Halford NG, Parry MAJ, Mottram DS. 2010b. Effects of sulphur nutrition during potato cultivation on the formation of acrylamide and aroma compounds during cooking. Food Chemistry 122, 753-760.
16. Eppendorfer WH, Bille SW. 1996. Free and total amino acid composition of edible parts of beans, kale, spinach, cauliflower and potatoes as influenced by nitrogen fertilisation and phosphorus and potassium deficiency. Journal of the Science of Food and Agriculture 71, 449-458. (Pubitemid 26309195)
17. Friedman M. 2003. Chemistry, biochemistry and safety of acrylamide. A review. Journal of Agricultural and Food Chemistry 51, 4504-4526.
18. Granvogl M, Jezussek M, Koehler P, Schieberle P. 2004. Quantitation of 3-aminopropionamide in potatoes-a minor but potent precursor in acrylamide formation. Journal of Agricultural and Food Chemistry 52, 4751-4757.
19. Granvogl M, Wieser H, Koehler P, Von Tucher S, Schieberle P. 2007. Influence of sulfur fertilization on the amounts of free amino acids in wheat. Correlation with baking properties as well as with 3-aminopropionamide and acrylamide generation during baking. Journal of Agricultural and Food Chemistry 55, 4271-4277. (Pubitemid 46867445)
20. Halford NG, Curtis TY, Muttucumaru N, Postles J, Mottram DS. 2011. Sugars in crop plants. Annals of Applied Biology 158, 1-25.
21. Hodge JE. 1953. Chemistry of the browning reaction in model systems. Journal of Agricultural and Food Chemistry 1, 928-943.
22. Hogervorst JG, Schouten LJ, Konings EJ, Goldbohm RA, van den Brandt PA. 2007. A prospective study of dietary acrylamide intake and the risk of endometrial, ovarian, and breast cancer. Cancer Epidemiology, Biomarkers and Prevention 16, 2304-2313. (Pubitemid 351196362)
23. Kumar D, Singh BP, Kumar P. 2004. An overview of the factors affecting sugar content of potatoes. Annals of Applied Biology 145, 247-256. (Pubitemid 41694603)
24. Lam H-M, Hsieh M-H, Coruzzi G. 1998. Reciprocal regulation of distinct asparagine synthetase genes by light and metabolites in Arabidopsis thaliana. The Plant Journal 16, 345-353.
25. Lea PJ, Miflin BJ. 2003. Glutamate synthase and the synthesis of glutamate in plants. Plant Physiology and Biochemistry 41, 555-564. (Pubitemid 36821381)
26. Lea PJ, Sodek L, Parry MA, Shewry PR, Halford NG. 2007. Asparagine in plants. Annals of Applied Biology 150, 1-26. (Pubitemid 46197519)
27. Lea PJ, Azevedo RA. 2007. Nitrogen use efficiency. 2. Amino acid metabolism. Annals of Applied Biology 151, 269-275. (Pubitemid 350178783)
28. Maillard LC. 1912. Action des acides aminés sur les sucres: formation des mélanödines par voie méthodique. Compte-rendu de l'Académie des Sciences 154, 66-68.
29. Malone JG, Mittova V, Ratcliffe RG, Kruger NJ. 2006. The response of carbohydrate metabolism in potato tubers to low temperature. Plant and Cell Physiology 47, 1309-1322. (Pubitemid 44441117)
30. McKibbin RS, Muttucumaru N, Paul MJ, Powers SJ, Burrell MM, Coates S, Purcell PC, Tiessen A, Geigenberger P, Halford NG. 2006. Production of high starch, low glucose potatoes through overexpression of the metabolic regulator, SnRK1. Plant Biotechnology Journal 4, 409-418. (Pubitemid 43886813)
31. Morales F, Capuano E, Fogliano V. 2008. Mitigation strategies to reduce acrylamide formation in fried potato products. Annals of the New York Academy of Sciences 1126, 89-100. (Pubitemid 351589313)
32. Mottram DS. 2007. The Maillard reaction: source of flavour in thermally processed foods. In: RG Berger, ed, Flavours and Fragrances: chemistry, bioprocessing and sustainability. Berlin: Springer-Verlag, 269-284.
33. Mottram DS, Wedzicha BL, Dodson AT. 2002. Acrylamide is formed in the Maillard reaction. Nature 419, 448-449.
34. Mucci LM, Wilson KM. 2008. Acrylamide intake through diet and human cancer risk. Journal of Agricultural and Food Chemistry 56, 6013-6019.
35. Mustafa A, Aman P, Andersson R, Kamal-Eldin A. 2007. Analysis of free amino acids in cereal products. Food Chemistry 105, 317-324. (Pubitemid 47016791)
36. Muttucumaru N, Halford NG, Elmore JS, Dodson AT, Parry M, Shewry PR, Mottram DS. 2006. The formation of high levels of acrylamide during the processing of flour derived from sulfate-deprived wheat. Journal of Agricultural and Food Chemistry 54, 8951-8955. (Pubitemid 44797548)
37. Nursten HE. 2005. The Maillard Reaction. Cambridge: Royal Society of Chemistry.
38. Nyström L, Lampi AM, Andersson AAM, et al. 2008. Phytochemicals and dietary fiber components in rye varieties in the HEALTHGRAIN diversity screen. Journal of Agricultural and Food Chemistry 56, 9758-9766.
39. Oruna-Concha MJ, Duckham SC, Ames JM. 2001. Comparison of volatile compounds isolated from the skin and flesh of four potato cultivars after baking. Journal of Agricultural and Food Chemistry 49, 2414-2421. (Pubitemid 32843268)
40. Roitsch T, González MC. 2004. Function and regulation of plant invertases: sweet sensations. Trends in Plant Science 9, 606-613. (Pubitemid 39558558)
41. Rommens CM, Ye J, Richael C, Swords K. 2006. Improving potato storage and processing characteristics through all-native DNA transformation. Journal of Agricultural and Food Chemistry 54, 9882-9887. (Pubitemid 46158984)
42. Rommens CM, Yan H, Swords K, Richael C, Ye J. 2008. Low acrylamide French fries and potato chips. Plant Biotechnology Journal 6, 843-853.
43. Shepherd LVT, Bradshaw JE, Dale MFB, McNicol JW, Pont SDA, Mottram DS, Davies HV. 2010. Variation in acrylamide producing potential in potato: segregation of the trait in a breeding population. Food Chemistry 123, 568-573.
44. Shewry PR. 2009. Wheat. Journal of Experimental Botany 60, 1537-1553.
45. Shewry PR, Zhao F-J, Gowa GB, Hawkins ND, Ward JL, Beale MH, Halford NG, Parry MAJ, Abécassis J. 2009. Sulphur nutrition differentially affects the distribution of asparagine in wheat grain. Journal of Cereal Science 50, 407-409.
46. Smith AM, Zeeman SC, Smith SM. 2005. Starch degradation. Annual Review of Plant Biology 56, 73-98.
47. Sowokinos J. 1990. Stress-induced Alterations in Carbohydrate Metabolism. Wallingford, UK: CAB International.
48. Stadler RH, Blank I, Varga N, Robert F, Hau J, Guy PA, Robert M-C, Riediker S. 2002. Acrylamide from Maillard reaction products. Nature 419, 449-450.
49. Stadler RH, Verzegnassi L, Varga N, Grigorov M, Studer A, Riediker S, Schilter B. 2003. Formation of vinylogous compounds in model Maillard reaction systems. Chemical Research in Toxicology 16, 1242-1250. (Pubitemid 37315214)
50. Taeymans D, Wood J, Ashby P, et al. 2004. A review of acrylamide: an industry perspective on research, analysis, formation and control. Critical Reviews in Food Science and Nutrition 44, 323-347. (Pubitemid 39357990)
51. Tareke E, Rydberg P, Karlsson P, Eriksson S, Törnqvist M. 2002. Analysis of acrylamide, a carcinogen formed in heated foodstuffs. Journal of Agricultural and Food Chemistry 50, 4998-5006. (Pubitemid 34856181)
52. Wilson KM, Mucci LA, Rosner BA, Willett WC. 2010. A prospective study on dietary acrylamide intake and the risk for breast, endometrial, and ovarian cancers. Cancer Epidemiology, Biomarkers and Prevention 19, 2503-2515.
53. Ye J, Shakya R, Shrestha P, Rommens CM. 2010. Tuber-specific silencing of the acid invertase gene substantially lowers the acrylamide-forming potential of potato. Journal of Agricultural and Food Chemistry 58, 12162-12167.
54. Zhao FJ, Hawkesford MJ, McGrath SP. 1999. Sulphur assimilation and effects on yield and quality of wheat. Journal of Cereal Science 30, 1-17. (Pubitemid 129532265)
55. Zrenner R, Salanoubat M, Willmitzer L, Sonnewald U. 1995. Evidence of the crucial role of sucrose synthase for sink strength using transgenic potato plants (Solanum tuberosum L.). The Plant Journal 7, 97-107.
56. Zyzak DV, Sanders RA, Stojanovic M, et al. 2003. Acrylamide formation mechanisms in heated foods. Journal of Agricultural and Food Chemistry 51, 4782-4787.