The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

Cell Metabolism

Volumn 8, Issue 6, 2008, Pages 502-511

  Silvestri, Laura ^a   Pagani, Alessia ^a   Nai, Antonella ^a   De Domenico, Ivana ^b   Kaplan, Jerry ^b   Camaschella, Clara ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

HUMDISEASE

Indexed keywords

HEMOJUVELIN; HEPCIDIN; MATRIPTASE; MATRIPTASE 2; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANEMIA; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME INHIBITION; HUMAN; HUMAN CELL; IRON DEFICIENCY; IRON METABOLISM; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; WILD TYPE; ZEBRA FISH;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; CELLS, CULTURED; ENDOPLASMIC RETICULUM; HELA CELLS; HUMANS; MEMBRANE PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; ZEBRAFISH;

DANIO RERIO; MUS;

EID: 56449096622     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2008.09.012     Document Type: Article

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