A noncanonical mu-1A-binding motif in the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes

Journal of Virology

Volumn 86, Issue 7, 2012, Pages 3944-3951

  Iijima, Sayuki ^a,b   Lee, Young Jung ^a   Ode, Hirotaka ^d   Arold, Stefan T ^c   Kimura, Nobuyuki ^a   Yokoyama, Masaru ^d   Sato, Hironori ^d   Tanaka, Yasuhito ^b   Strebel, Klaus ^e   Akari, Hirofumi ^a,f  

^a NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CELL PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; METHIONINE; MU 1A PROTEIN; NEF PROTEIN; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; VALINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE EVASION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; T LYMPHOCYTE; VIRUS IMMUNITY;

ADAPTOR PROTEIN COMPLEX 1; ADAPTOR PROTEIN COMPLEX MU SUBUNITS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; DOWN-REGULATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV INFECTIONS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PROTEIN BINDING; T-LYMPHOCYTES;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84861321773     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06257-11     Document Type: Article

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