The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retroviruses

Journal of Virology

Volumn 70, Issue 12, 1996, Pages 8285-8300

  Bour, Stephan ^a   Strebel, Klaus ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; ENVELOPE PROTEIN; GAG PROTEIN; POL PROTEIN; VPU PROTEIN;

ARTICLE; CHIMERA; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; PRIORITY JOURNAL; PROGENY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS INFECTION; VIRUS PARTICLE;

EID: 0029956763     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.12.8285-8300.1996     Document Type: Article

References (49)

1. Adachi, A., H. E. Gendelman, S. Koenig, T. Folks, R. Willey, A. Rabson, and M. A. Martin. 1986. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:284-291.
2. Agy, M. B., L. R. Frumkin, L. Corey, R. W. Coombs, S. M. Wolinsky, J. Koehler, W. R. Morton, and M. G. Katze. 1992. Infection of Macaca nemestrina by human immunodeficiency virus type-1. Science 257:103-106.
3. Bour, S. Unpublished data.
4. Bour, S., F. Boulerice, and M. A. Wainberg. 1991. Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1. J. Virol. 65:6387-6396.
5. Bour, S., U. Schubert, K. Peden, and K. Strebel. 1996. The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor? J. Virol. 70:820-829.
6. Bour, S., U. Schubert, and K. Strebel. 1995. The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation. J. Virol. 69:1510-1520.
7. Chen, M. V., F. Maldarelli, M. K. Karczewski, R. L. Willey, and K. Strebel. 1993. Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity. J. Virol. 67:3877-3884.
8. Cohen, E. A., E. F. Terwilliger, J. G. Sodroski, and W. A. Haseltine. 1988. Identification of a protein encoded by the vpu gene of HIV-1. Nature (London) 334:532-534.
9. Crise, B., L. Buonocore, and J. K. Rose. 1990. CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor. J. Virol. 64:5585-5593.
10. Cucchiarini, M., L. Cagnon, V. Giordanengp, A. Doglio, and J.-C. Lefebvre. 1995. Induction by human immunodeficiency viruses types 1 and 2 of degradation of CD4 hut not of a CD4 mutant unable to bind viral envelope glycoproteins. J. Acquired Immune Defic. Syndr. 8:427-436.
11. Deen, K. C., J. S. McDougal, R. Inaker, G. Folena-Wasserman, J. Arthos, J. Rosenberg, P. J. Maddon, R. Axel, and R. W. Sweet. 1988. A soluble form of CD4 (T4) protein inhibits AIDS virus infection. Nature (London) 331:82-84.
12. Friborg, J., A. Ladha, H. G. Göttlinger, W. A. Haseltine, and E. A. Cohen. 1995. Functional analysis af the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein. J. Acquired Immune Defic. Syndr. 8:10-22.
13. Friborg, J., X.-J. Yao, F. Boisvert, S. Garzon, and E. A. Cohen. 1994. Mutational analysis of the HIV-1 Vpu protein. Leukemia 8:S156-S162.
14. Geraghty, R. J., and A. T. Panganiban. 1993. Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function. J. Virol. 67:4190-4194.
15. Göttlinger, H. G., T. Dorfman, E. A. Cohen, and W. A. Haseltine. 1993. Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses. Proc. Natl. Acad. Sci. USA 90:7381-7385.
16. Huet, T., A. Cheynier, A. Meyerhans, G. Roelants, and S. Wain-Hobson. 1990. Genetic organization of a chimpanzee lentivirus related to HIV-1. Nature (London) 345:356-359.
17. Ivey-Hoyle, M., J. S. Culp, M. A. Chaikin, B. D. Hellmig, T. J. Matthews, R. W. Sweet, and M. Rosenberg. 1991. Envelope glycoproteins from biologically diverse isolates of immunodeficiency viruses have widely different affinities for CD4. Proc. Natl. Acad. Sci. USA 88:512-516.
18. Jabbar, M. A., and D. P. Nayak. 1990. Intracellular interaction of human immunodeficiency virus type 1 (ARV-2) envelope glycoprotein gp160 with CD4 blocks the movement and maturation of CD4 to the plasma membrane. J. Virol. 64:6297-6304.
19. Klimkait, T., K. Strebel, M. D. Hoggan, M. A. Martin, and J. M. Orenstein. 1990. The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release. J. Virol. 64:621-629.
20. Kong, L. I., S. Lee, J. C. Kappes, J. S. Parkin, D. Decker, J. A. Hoxie, B. H. Hahn, and G. M. Shaw. 1988. West African HIV-2-related human retrovirus with attenuated cytopathicity. Science 240:1525-1529.
21. Kumar, P., H. Hui, J. C. Kappes, B. S. Haggarty, J. A. Hoxie, S. K. Arya, G. M. Shaw, and B. H. Hahn. 1990. Molecular characterization of an attenuated human immunodeficiency virus type 2 isolate. J. Virol. 64:890-901.
22. Lenburg, M. E., and N. R. Landau. 1993. Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4. J. Virol. 67:7238-7245.
23. Li, J. T., M. Halloran, C. I. Lord, A. Watson, J. Ranchalis, M. Fung, N. L. Letvin, and J. G. Sodroski. 1995. Persistent infection of macaques with simian-human immunodeficiency viruses. J. Virol. 69:7061-7071.
24. Maldarelli, F., M. Y. Chen, R. L. Willey, and K. Strebel. 1993. Human immunodeficiency virus type 1 Vpu protein is an oligomeric type 1 integral membrane protein. J. Virol. 67:5056-5061.
25. Marcus-Sekura, C. J., A. M. Woerner, M. Zweig, D. L. Court, J. G. Levin, and M. Klutch. 1990. Expression of HIV-1 integrase in E. coli: immunological analysis of the recombinant protein. AIDS Res. Hum. Retroviruses 6:1399-1408. (Erratum, 7:636, 1991.)
26. Matsuda, Z., M.-J. Chou, M. Matsuda, J.-H. Huang, Y.-M. Chen, R. Redfield, K. Mayer, M. Essex, and T.-H. Lee. 1988. Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome. Proc. Natl. Acad. Sci. USA 85:6968-6972.
27. Mulligan, M. J., G. J. Douglas Ritter, M. A. Chaikin, G. V. Yamshchikov, P. Kumar, B. H. Hahn, R. W. Sweet, and R. W. Compans. 1992. Human immunodeficiency virus type 2 envelope glycoprotein: differential CD4 interactions of soluble gp 120 versus the assembled envelope complex. Virology 187:233-241.
28. Mulligan, M. J., G. V. Yamshchikov, G. Ritter, Jr., F. Gao, M. J. Jin, C. D. Nail, C. P. Spies, B. H. Hahn, and R. W. Compans. 1992. Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types. J. Virol. 66:3971-3975.
29. Naidu, Y. M., H. W. Kestler III, Y. Li, C. V. Butler, D. P. Silva, D. K. Schmidt, C. D. Troup, P. K. Seghal, P. Sonigo, M. D. Daniel, and R. C. Desrosiers. 1988. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J. Virol. 62:4691-4696.
30. Rey, M. A., B. Krust, A. G. Laurent, L. Montagnier, and A. G. Hovanessian. 1989. Characterization of human immunodeficiency virus type 2 envelope glycoproteins: dimerization of the glycoprotein precursor during processing. J. Virol. 63:647-658.
31. Ritter, G. D., Jr., G. Yamshchikov, S. J. Cohen, and M. J. Mulligan. 1996. Human immunodeficiency virus type 2 glycoprotein enhancement of particle budding: role of the cytoplasmic domain. J. Virol. 70:2669-2673.
32. Ryan-Graham, M. A., and W. C. K. Peden. 1995. Both virus and host components are important for the manifestation of a Nef-minus phenotype in HIV-1 and HIV-2. Virology 213:158-168.
33. Schubert, U., S. Bour, A. V. Ferrer-Montiel, M. Montai, F. Maldarelli, and K. Strebel. 1996. The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains. J. Virol. 70:809-819.
34. Schubert, U., K. A. Clouse, and K. Strebel. 1995. Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytes. J. Virol. 69:7699-7711.
35. Schubert, U., P. Henklein, B. Boldyreff, E. Wingender, K. Strebel, and T. Porstmann. 1994. The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif. J. Mol. Biol. 236:16-25.
36. Schubert, U., T. Schneider, P. Henklein, K. Hoffmann, E. Berthold, H. Hauser, G. Pauli, and T. Porstmann. 1992. Human immunodeficiency virus type-1-encoded Vpu protein is phosphorylated by casein kinase II. Eur. J. Biochem. 204:875-883.
37. Schubert, U., and K. Strebel. 1994. Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein arc regulated by phosphorylation and occur in different cellular compartments. J. Virol. 68:2260-2271.
38. Schwartz, S., B. K. Felder, E. M. Fenyö, and G. N. Pavlakis. 1990. Env and Vpu proteins of human immunodeficiency virus type 1 arc produced from multiple bicistronic mRNAs. J. Virol. 64:5448-5456.
39. Shibata, R. Unpublished data.
40. Shibata, R., M. D. Hoggan, C. Broscius, G. Englund, T. S. Theodore, A. Buckler-White, L. O. Arthur, Z. Israel, A. Schultz, H. C. Lane, and M. A. Martin. 1995. Isolation and characterization of a syncytium-inducing, macrophage/T-cell line-tropic human immunodeficiency virus type 1 isolate that readily infects chimpanzee cells in vitro and in vivo. J. Virol. 69:4453-4462.
41. Shibata, R., M. Kawamura, H. Sakai, M. Hayami, A. Ishimoto, and A. Adachi. 1991. Generation of a chimeric human immunodeficiency virus infectious to monkey peripheral blood mononuclear cells. J. Virol. 65:3514-3520.
42. Strebel, K., T. Klimkait, F. Maldarelli, and M. A. Martin. 1989. Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein. J. Virol. 63:3784-3791.
43. Strebel, K., T. Klimkait, and M. A. Martin. 1988. A novel gene of HIV-1, vpu, and its 16-kilodalton product. Science 241:1221-1223.
44. Terwilliger, E. F., E. A. Cohen, Y. C. Lu, J. G. Sodroski, and W. A. Haseltine. 1989. Functional role of human immunodeficiency virus type 1 vpu. Proc. Nail. Acad. Sci. USA 86:5163-5167.
45. Vincent, M. J., N. U. Raja, and M. A. Jabbar. 1993. Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum. J. Virol. 67:5538-5549.
46. Willey, R. L., F. Maldarelli, M. A. Martin, and K. Strebel. 1992. Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4. J. Virol. 66:7193-7200.
47. Willey, R. L., F. Maldarelli, M. A. Martin, and K. Strebel. 1992. Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes. J. Virol. 66:226-234.
48. Yao, X. J., S. Garzon, F. Boisvert, W. A. Haseltine, and E. A. Cohen. 1993. The effect of vpu on HIV-1-induced syncytia formation. J. Acquired Immune Defic. Syndr. 6:135-141.
49. Yao, X. J., H. Göttlingr, W. A. Haseltine, and E. A. Cohen. 1992. Envelope glycoprotein and CD4 independence of Vpu-facilitatcd human immunode-ficiency virus type 1 capsid export. J. Virol. 66:5119-5126.