Effective down-regulation of Breast Cancer Resistance Protein (BCRP) by siRNA delivery using lipid-substituted aliphatic polymers

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 81, Issue 1, 2012, Pages 33-42

  Aliabadi, Hamidreza Montazeri ^a   Landry, Breanne ^a   Mahdipoor, Parvin ^a   Hsu, Charlie Y M ^a   Uludaǧ, Hasan ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Breast Cancer Resistance Protein (BCRP); Lipid substitution; Multidrug resistance; Polyethyleneimine; siRNA; siRNA delivery

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; LIPID SUBSTITUTED ALIPHATIC POLYMER; MITOXANTRONE; POLYMER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CYTOTOXICITY; DOWN REGULATION; DRUG DELIVERY SYSTEM; FEASIBILITY STUDY; HUMAN; HUMAN CELL; IC 50; LIPOPHILICITY; MOLECULAR WEIGHT; PARTICLE SIZE; PROTEIN EXPRESSION;

ANIMALS; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; DOGS; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; FEASIBILITY STUDIES; GENE SILENCING; INHIBITORY CONCENTRATION 50; LIPIDS; MITOXANTRONE; MOLECULAR WEIGHT; NEOPLASM PROTEINS; POLYMERS; RNA, SMALL INTERFERING; TIME FACTORS;

EID: 84861098418     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.01.011     Document Type: Article

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