Cationic polymer-mediated small interfering RNA delivery for P-glycoprotein down-regulation in tumor cells

Cancer

Volumn 116, Issue 23, 2010, Pages 5544-5554

  Abbasi, Meysam ^a   Lavasanifar, Afsaneh ^a   Berthiaume, Luc G ^a   Weinfeld, Michael ^a   Uludaǧ, Hasan ^a,b  

^a CROSS CANCER INSTITUTE   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

chemotherapy; multidrug resistance; permeability glycoprotein; polymeric carriers; small interfering RNA

Indexed keywords

DOXORUBICIN; GLYCOPROTEIN P; PACLITAXEL; POLYMER; SMALL INTERFERING RNA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL VIABILITY; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DOWN REGULATION; DRUG TARGETING; DRUG UPTAKE; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

CATIONS; CELL LINE, TUMOR; DOWN-REGULATION; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; FEASIBILITY STUDIES; GENE TRANSFER TECHNIQUES; HUMANS; LYSINE; NEOPLASMS; P-GLYCOPROTEIN; PACLITAXEL; POLYMERS; RNA, SMALL INTERFERING;

EID: 78649605959     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25321     Document Type: Article

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