메뉴 건너뛰기




Volumn 4 E, Issue 4, 2012, Pages 1528-1541

The role of cancer stem cells in relapse of solid tumors

Author keywords

Breast cancer; Cancer relapse; Cancer stem cells; Glioblastoma; Melanoma; Review

Indexed keywords

ABAMECTIN; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; COMPLEMENTARY DNA; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ETOPOSIDE; FIBRONECTIN; HERMES ANTIGEN; INTERLEUKIN 8; KISSPEPTIN; KISSPEPTIN 1; MASPIN; METFORMIN; MULTIDRUG RESISTANCE PROTEIN 1; NESTIN; NIGERICIN; NOTCH RECEPTOR; PACLITAXEL; PROTEIN P53; SALINOMYCIN; SONIC HEDGEHOG PROTEIN; TEMOZOLOMIDE; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; WNT PROTEIN;

EID: 84860873820     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (132)

References (122)
  • 1
    • 0018848780 scopus 로고
    • Assumptions in the radiotherapy of glioblastoma
    • Fred H Hochberg and Amy Pruitt: Assumptions in the radiotherapy of glioblastoma. Neurology 30(9), 907-911 (1980) (Pubitemid 10059239)
    • (1980) Neurology , vol.30 , Issue.9 , pp. 907-911
    • Hochberg, F.H.1    Pruitt, A.2
  • 2
    • 84888018239 scopus 로고    scopus 로고
    • http://foodforbreastcancer.com/news/follow-up-Afterbreast-cancer-should- Take-into-Account-risk-of-relapse)
  • 3
    • 84888046097 scopus 로고    scopus 로고
    • http://news.cancerconnect.com/recurrent-prostate-cancer/)
  • 4
    • 84888058175 scopus 로고    scopus 로고
    • http://news.cancerconnect.com/recurrentosteosarcoma/#-edn1)
  • 5
    • 84888063320 scopus 로고    scopus 로고
    • http://www.physorg.com/news/2011-01-Treatment-relapsebladder-cancer- patients.html)
  • 6
    • 84888043206 scopus 로고    scopus 로고
    • Local recurrence rate following wide local excision and immediate reconstruction
    • Stephen R Sullivan, Der-Zen Liu, David W Mathes and Frank F Isik. Head and Neck Malignant Melanoma: Local Recurrence Rate Following Wide Local Excision and Immediate Reconstruction. Ann Plast Surg 4 (2011)
    • (2011) Ann Plast Surg , vol.4
    • Sullivan, S.R.1    Liu, D.-Z.2    Mathes, D.W.3    Isik, F.F.4    Melanoma, N.M.5
  • 7
    • 0032462716 scopus 로고    scopus 로고
    • Patterns of relapse and response to retreatment in patients with metastatic melanoma or renal cell carcinoma who responded to interleukin-2- based immunotherapy
    • Dong-Seol Lee, Donald E White, Rachel Hurst, Steven A Rosenberg and James C Yang. Patterns of relapse and response to retreatment in patients with metastatic melanoma or renal cell carcinoma who responded to interleukin-2-based immunotherapy. Cancer J Sci Am 4(2), 86-93 (1998) (Pubitemid 29090712)
    • (1998) Cancer Journal from Scientific American , vol.4 , Issue.2 , pp. 86-93
    • Lee, D.S.1    White, D.E.2    Hurst, R.3    Rosenberg, S.A.4    Yang, J.C.5
  • 11
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • John E Dick: Stem cell concepts renew cancer research. Blood 112, 4793-4807 (2008)
    • (2008) Blood , vol.112 , pp. 4793-4807
    • Dick, J.E.1
  • 12
    • 59049105873 scopus 로고    scopus 로고
    • Die hard: Are cancer stem cells the bruce willises of tumor biology?
    • Akos Fábián, Mark Barok, Gyorgy Vereb, and Janos Szöllosi: Die hard: are cancer stem cells the Bruce Willises of tumor biology? Cytometry A 75(1), 67-74 (2009)
    • (2009) Cytometry A , vol.75 , Issue.1 , pp. 67-74
    • Fábián, A.1    Barok, M.2    Vereb, G.3    Szöllosi, J.4
  • 13
    • 77956178360 scopus 로고    scopus 로고
    • Emt, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
    • Akanksha Singh, and Jeffrey Settleman. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 29(34), 4741-4751 (2010)
    • (2010) Oncogene , vol.29 , Issue.34 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 14
    • 79551522569 scopus 로고    scopus 로고
    • Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma
    • Chao Chen, Yan Wei, Michael Hummel, Thomas K Hoffmann, Manfred Gross, Andreas M Kaufmann and Albers E Albers. Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma. PLoS One 6(1), e16466 (2011)
    • (2011) PLoS One , vol.6 , Issue.1
    • Chen, C.1    Wei, Y.2    Hummel, M.3    Hoffmann, T.K.4    Gross, M.5    Kaufmann, A.M.6    Albers, A.E.7
  • 15
    • 78650223132 scopus 로고    scopus 로고
    • Molecular signature of epithelial-mesenchymal transition (emt) in human prostate cancer bone metastasis
    • Seema Sethi, Jill Macoska, Wei Chen and Fazlul H Sarkar. Molecular signature of epithelial-mesenchymal transition (EMT) in human prostate cancer bone metastasis. Am J Transl Res 3(1), 90-99 (2010)
    • (2010) Am J Transl Res , vol.3 , Issue.1 , pp. 90-99
    • Sethi, S.1    Macoska, J.2    Chen, W.3    Sarkar, F.H.4
  • 16
    • 85057904989 scopus 로고    scopus 로고
    • Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
    • Bin Bao, Zhiwei Wang, Shadan Ali, Dejuan Kong, Yiwei Li, Aamir Ahmad, Sanjeev Banerjee, Asfar S Azmi, Lucio Miele, and Fazlul H Sarkar. Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett April 2 (2011)
    • (2011) Cancer Lett April , vol.2
    • Bao, B.1    Wang, Z.2    Ali, S.3    Kong, D.4    Yiwei, Li.5    Ahmad, A.6    Banerjee, S.7    Azmi, A.S.8    Miele, L.9    Sarkar, F.H.10
  • 18
    • 77649338990 scopus 로고    scopus 로고
    • Primary brain tumors, neural stem cell, and brain tumor cancer cells: Where is the link?
    • Isabelle Germano, Victoria Swiss and Patrizia Casaccia. Primary brain tumors, neural stem cell, and brain tumor cancer cells: where is the link? Neuropharmacology 58(6), 903-910 (2010)
    • (2010) Neuropharmacology , vol.58 , Issue.6 , pp. 903-910
    • Germano, I.1    Swiss, V.2    Casaccia, P.3
  • 19
    • 52049118079 scopus 로고    scopus 로고
    • The role of metastasis suppressor genes in metastatic dormancy
    • Christine E Horak, Jong Heun Lee, Jean-Claude Marshall, Martin Shreeve and Patricia S Steeg. The role of metastasis suppressor genes in metastatic dormancy. APMIS 116(7-8), 586-501(2008)
    • (2008) APMIS , vol.116 , Issue.7-8 , pp. 586-501
    • Horak, C.E.1    Lee, J.H.2    Marshall, J.-C.3    Shreeve, M.4    Steeg, P.S.5
  • 20
    • 77950595309 scopus 로고    scopus 로고
    • The Nm23-H1 metastasis suppressor as a translational target
    • Jean-Claude Marshall, Joshua Collins, Natascia Marino and Patricia Steeg. The Nm23-H1 metastasis suppressor as a translational target. Eur J Cancer 46(7), 1278-1282 (2010)
    • (2010) Eur J Cancer , vol.46 , Issue.7 , pp. 1278-1282
    • Marshall, J.-C.1    Collins, J.2    Marino, N.3    Steeg, P.4
  • 21
    • 33645008126 scopus 로고    scopus 로고
    • Tumor suppressive maspin and epithelial homeostasis
    • Jaron Lockett, Shuping Yin, Xiaohua Li, Yonghong Meng and Shijie Sheng. Tumor suppressive maspin and epithelial homeostasis. J Cell Biochem 97(4), 651-660 (2006)
    • (2006) J Cell Biochem , vol.97 , Issue.4 , pp. 651-660
    • Lockett, J.1    Yin, S.2    Xiaohua, Li.3    Meng, Y.4    Sheng, S.5
  • 23
    • 56049111865 scopus 로고    scopus 로고
    • Drug development against metastasis-related genes and their pathways: A rationale for cancer therapy
    • Megumi Iiizumi, Wen Liu, Sudha K Pai, Eiji Furuta and Kounosuke Watabe. Drug development against metastasis-related genes and their pathways: a rationale for cancer therapy. Biochim Biophys Acta 1786(2), 87-04 (2008)
    • (2008) Biochim Biophys Acta , vol.1786 , Issue.2 , pp. 87-04
    • Iiizumi, M.1    Liu, W.2    Pai, S.K.3    Furuta, E.4    Watabe, K.5
  • 24
    • 77950580049 scopus 로고    scopus 로고
    • The kiss1 metastasis suppressor: A good night kiss for disseminated cancer cells
    • Benjamin H Beck and Danny R Welch. The KISS1 metastasis suppressor: a good night kiss for disseminated cancer cells. Eur J Cancer 46(7), 1283-1289 (2010)
    • (2010) Eur J Cancer , vol.46 , Issue.7 , pp. 1283-1289
    • Beck, B.H.1    Welch, D.R.2
  • 25
    • 67651160649 scopus 로고    scopus 로고
    • Cd4(+) t cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • David G DeNardo, Jairo B Barreto, Pauline Andreu, Lesley Vasquez, David Tawfik, Nikita Kolhatkar and Lisa M Coussens. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16(2), 91-102 (2009)
    • (2009) Cancer Cell , vol.16 , Issue.2 , pp. 91-102
    • DeNardo, D.G.1    Barreto, J.B.2    Andreu, P.3    Vasquez, L.4    Tawfik, D.5    Kolhatkar, N.6    Coussens, L.M.7
  • 26
    • 77951228314 scopus 로고    scopus 로고
    • The role of hypoxia and acidosis in promoting metastasis and resistance to chemotherapy
    • Katie DeClerck and Randolph C Elble. The role of hypoxia and acidosis in promoting metastasis and resistance to chemotherapy. Front Biosci 15, 213-225 (2010)
    • (2010) Front Biosci , vol.15 , pp. 213-225
    • DeClerck, K.1    Elble, R.C.2
  • 27
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • DOI 10.1038/nm0797-730
    • Dominique Bonnet and John E Dick: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3, 730-737 (1997) (Pubitemid 27298715)
    • (1997) Nature Medicine , vol.3 , Issue.7 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 28
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • DOI 10.1038/nature05372, PII NATURE05372
    • Catherine A O'Brien, Aaron Pollett, Steven Gallinger and John E Dick: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445 (7123), 106-110 (2007) (Pubitemid 46067310)
    • (2007) Nature , vol.445 , Issue.7123 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 29
    • 0029983762 scopus 로고    scopus 로고
    • Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell
    • DOI 10.1006/dbio.1996.0090
    • Brent A Reynolds and Samuel Weiss: Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev Biol 175(1), 1-13 (1996) (Pubitemid 26150042)
    • (1996) Developmental Biology , vol.175 , Issue.1 , pp. 1-13
    • Reynolds, B.A.1    Weiss, S.2
  • 30
    • 77957961187 scopus 로고    scopus 로고
    • The role of tumor initiating cells in drug resistance of breast cancer: Implications for future therapeutic approaches
    • Lara Lacerda, Lajos Pusztai and Wendy A Woodward: The role of tumor initiating cells in drug resistance of breast cancer: Implications for future therapeutic approaches. Drug Resist Updat 13(4-5), 99-108 (2010)
    • (2010) Drug Resist Updat , vol.13 , Issue.4-5 , pp. 99-108
    • Lacerda, L.1    Pusztai, L.2    Woodward, W.A.3
  • 31
    • 62549108159 scopus 로고    scopus 로고
    • Abc transporters, drug resistance, and cancer stem cells
    • Michael Dean. ABC transporters, drug resistance, and cancer stem cells. J Mammary Gland Biol Neoplasia 14(1), 3-9 (2009)
    • (2009) J Mammary Gland Biol Neoplasia , vol.14 , Issue.1 , pp. 3-9
    • Dean, M.1
  • 32
    • 20144364789 scopus 로고    scopus 로고
    • ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma
    • DOI 10.1158/0008-5472.CAN-04-3327
    • Natasha Y Frank, Armen Margaryan, Ying Huang, Tobias Schatton, Ana Maria Waaga-Gasser, Martin Gasser, Mohamed H Sayegh, Wolfgang Sadee and Markus H Frank: ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Res 65(10), 4320-4333 (2005) (Pubitemid 40775671)
    • (2005) Cancer Research , vol.65 , Issue.10 , pp. 4320-4333
    • Frank, N.Y.1    Margaryan, A.2    Huang, Y.3    Schatton, T.4    Waaga-Gasser, A.M.5    Gasser, M.6    Sayegh, M.H.7    Sadee, W.8    Frank, M.H.9
  • 33
    • 71049189661 scopus 로고    scopus 로고
    • Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting abcg2/bcrp-mediated drug export
    • Ryohei Katayama, Sumie Koike, Shigeo Sato, Yoshikazu Sugimoto, Takashi Tsuruo and Naoya Fujita: Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. Cancer Sci 100(11), 2060-2068 (2009)
    • (2009) Cancer Sci , vol.100 , Issue.11 , pp. 2060-2068
    • Katayama, R.1    Koike, S.2    Sato, S.3    Sugimoto, Y.4    Tsuruo, T.5    Fujita, N.6
  • 34
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • DOI 10.1038/nm0901-1028
    • Sheng Zhou, John D Schuetz, Kevin D Bunting, Anne-Marie Colapietro, Janardhan Sampath, John J Morris, Irina Lagutina, Gerard Grosveld, Mitsujiro Osawa, Hiromitsu Nakauchi, and Brain P Sorrentino: The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 7(9), 1028-1034 (2001) (Pubitemid 32937383)
    • (2001) Nature Medicine , vol.7 , Issue.9 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3    Colapietro, A.-M.4    Sampath, J.5    Morris, J.J.6    Lagutina, I.7    Grosveld, G.C.8    Osawa, M.9    Nakauchi, H.10    Sorrentino, B.P.11
  • 36
    • 22244433866 scopus 로고    scopus 로고
    • - cancer cells are similarly tumorigenic
    • DOI 10.1158/0008-5472.CAN-05-0592
    • Lubna Patrawala, Tammy Calhoun, Robin Schneider-Broussard, Jianjun Zhou, Kent Claypool and Dean G Tang. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2-cancer cells are similarly tumorigenic. Cancer Res 65(14), 6207-6219 (2005) (Pubitemid 40994406)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 6207-6219
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3    Zhou, J.4    Claypool, K.5    Tang, D.G.6
  • 37
    • 77956407722 scopus 로고    scopus 로고
    • Mechanisms of cancer metastasis: Involvement of cancer stem cells?
    • Mehdy Ratajczak, Maciej Tarnowski, Magdalena Staniszewska, T Sroczynski and Bridget Banach: Mechanisms of cancer metastasis: involvement of cancer stem cells? Minerva Med 101(3), 179-191 (2010)
    • (2010) Minerva Med , vol.101 , Issue.3 , pp. 179-191
    • Ratajczak, M.1    Tarnowski, M.2    Staniszewska, M.3    Sroczynski, T.4    Banach, B.5
  • 38
    • 77957591579 scopus 로고    scopus 로고
    • Targeting breast cancer stem cells
    • Shujun Liu and Max S Wicha. Targeting breast cancer stem cells. J Clin Oncol 28(25), 4006-4012 (2010)
    • (2010) J Clin Oncol , vol.28 , Issue.25 , pp. 4006-4012
    • Liu, S.1    Wicha, M.S.2
  • 39
    • 78751640633 scopus 로고    scopus 로고
    • Inhibition of sonic hedgehog and notch pathways enhances sensitivity of cd 133(+) glioma stem cells to temozolomide therapy
    • Ilya V Ulasov, Suvobroto Nandi, Mahua Dey, Adam M Sonabend and Maciej S Lesniak: Inhibition of Sonic Hedgehog and Notch Pathways Enhances Sensitivity of CD 133(+) Glioma Stem Cells to Temozolomide Therapy. Mol Med 17(1-2), 103-112 (2011)
    • (2011) Mol Med , vol.17 , Issue.1-2 , pp. 103-112
    • Ulasov, I.V.1    Nandi, S.2    Dey, M.3    Sonabend, A.M.4    Lesniak, M.S.5
  • 40
    • 68549087254 scopus 로고    scopus 로고
    • The hedgehog signalling pathway as a therapeutic target in early breast cancer development
    • Sandra A O'Toole, Alexander Swarbrick and Robert L Sutherland. The Hedgehog signalling pathway as a therapeutic target in early breast cancer development. Expert Opin Ther Targets 13(9), 1095-1103 (2009)
    • (2009) Expert Opin Ther Targets , vol.13 , Issue.9 , pp. 1095-1103
    • O'Toole, S.A.1    Swarbrick, A.2    Sutherland, R.L.3
  • 41
    • 36248953716 scopus 로고    scopus 로고
    • Mammary stem cells and breast cancer - Role of notch signalling
    • DOI 10.1007/s12015-007-0023-5, PII SCR32169
    • Gillian Farnie and Robert Clarke. Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev 3 (2), 169-175 (2007) (Pubitemid 350129719)
    • (2007) Stem Cell Reviews , vol.3 , Issue.2 , pp. 169-175
    • Farnie, G.1    Clarke, R.B.2
  • 42
    • 50849111710 scopus 로고    scopus 로고
    • Rational targeting of notch signaling in cancer
    • Pietro Rizzo, Clodia Osipo, Kyle Foreman, Todd Golde, Benjamin Osborne and Lucio Miele. Rational targeting of Notch signaling in cancer. Oncogene 27(38), 5124-5131 (2008)
    • (2008) Oncogene , vol.27 , Issue.38 , pp. 5124-5131
    • Rizzo, P.1    Osipo, C.2    Foreman, K.3    Golde, T.4    Osborne, B.5    Miele, L.6
  • 43
    • 54049096261 scopus 로고    scopus 로고
    • Her2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
    • Hasan Korkaya, Ariel Paulson, Flora Iovino and Max S Wicha. HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 27(47), 6120-6130 (2008)
    • (2008) Oncogene , vol.27 , Issue.47 , pp. 6120-6130
    • Korkaya, H.1    Paulson, A.2    Iovino, F.3    Wicha, M.S.4
  • 45
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting wnt, notch, and hedgehog pathways
    • Naoko Takebe, Pamela J Harris, Ronald Q Warren and Percy Ivy. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Onco 8(2), 97-106 (2011)
    • (2011) Nat Rev Clin Onco , vol.8 , Issue.2 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3    Ivy, P.4
  • 48
    • 0345599013 scopus 로고    scopus 로고
    • Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of β-catenin signaling, Slug, and MAPK
    • DOI 10.1083/jcb.200308162
    • Maralice Conacci-Sorrell, Inbal Simcha, Tamar Ben-Yedidia, Janna Blechman, Pierre Savagner and Avri Ben-Ze'ev. Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK. J Cell Biol 163, 847-857 (2003) (Pubitemid 37517891)
    • (2003) Journal of Cell Biology , vol.163 , Issue.4 , pp. 847-857
    • Conacci-Sorrell, M.1    Simcha, I.2    Ben-Yedidia, T.3    Blechman, J.4    Savagner, P.5    Ben-Ze'Ev, A.6
  • 49
    • 0345700653 scopus 로고    scopus 로고
    • Twist is up-regulated in response to wnt1 and inhibits mouse mammary cell differentiation
    • Louise R Howe, Osamu Watanabe, James Leonard and Anthony M Brown. Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation. Cancer Res 63(8), 1906-2013 (2003)
    • (2003) Cancer Res , vol.63 , Issue.8 , pp. 1906-2013
    • Howe, L.R.1    Watanabe, O.2    Leonard, J.3    Brown, A.M.4
  • 50
    • 67650496215 scopus 로고    scopus 로고
    • A novel lung metastasis signature links wnt signaling with cancer cell self-renewal and epithelialmesenchymal transition in basal-like breast cancer
    • Theresa A DiMeo, Kristen Anderson, Pushkar Phadke, Chang Fan, Charles M Perou, Steven Naber and Charlotte Kuperwasser. A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelialmesenchymal transition in basal-like breast cancer. Cancer Res 69(13), 5364-5373 (2009)
    • (2009) Cancer Res , vol.69 , Issue.13 , pp. 5364-5373
    • DiMeo, T.A.1    Anderson, K.2    Phadke, P.3    Fan, C.4    Perou, C.M.5    Naber, S.6    Kuperwasser, C.7
  • 52
    • 33745600820 scopus 로고    scopus 로고
    • Asymmetric and symmetric stem-cell divisions in development and cancer
    • DOI 10.1038/nature04956, PII N04956
    • Sean J Morrison and Judith Kimble: Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 441(7097), 1068-1074 (2006) (Pubitemid 43990718)
    • (2006) Nature , vol.441 , Issue.7097 , pp. 1068-1074
    • Morrison, S.J.1    Kimble, J.2
  • 55
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • DOI 10.1101/gad.1061803
    • Gabriela Dontu, Wissam M Abdallah, Jessica M Foley, Kyle W Jackson, Michael F Clarke, Mari J Kawamura and Max S Wicha: In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17(10), 1253-1270 (2003) (Pubitemid 36583168)
    • (2003) Genes and Development , vol.17 , Issue.10 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3    Jackson, K.W.4    Clarke, M.F.5    Kawamura, M.J.6    Wicha, M.S.7
  • 56
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Suling Liu, Gabriela Dontu, Ilia D Mantle, Shivani Patel, Nam-Shik Ahn, Kyle W Jackson, Prerna Suri and Max S Wicha: Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 66(12), 6063-6071 (2006)
    • (2006) Cancer Res , vol.66 , Issue.12 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3    Patel, S.4    Ahn, N.-S.5    Jackson, K.W.6    Suri, P.7    Wicha, M.S.8
  • 59
    • 39449095723 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype
    • DOI 10.1158/0008-5472.CAN-07-2017
    • David Sarrió, Socorro Maria Rodriguez-Pinilla, David Hardisson, Cano Amparo, Moreno-Bueno Ema, and Palacios Jose: Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res 68(4), 989-997 (2008) (Pubitemid 351272216)
    • (2008) Cancer Research , vol.68 , Issue.4 , pp. 989-997
    • Sarrio, D.1    Rodriguez-Pinilla, S.M.2    Hardisson, D.3    Cano, A.4    Moreno-Bueno, G.5    Palacios, J.6
  • 61
    • 78049308800 scopus 로고    scopus 로고
    • Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast
    • Aleix Prat, Joel S Parker, Olga Karginova, Cheng Fan, Chad Livasy, Jason I Herschkowitz, Xiaping He and Charles M Perou: Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res 12(5), R68 (2010)
    • (2010) Cancer Res , vol.12 , Issue.5
    • Prat, A.1    Parker, J.S.2    Karginova, O.3    Fan, C.4    Livasy, C.5    Herschkowitz, J.I.6    He, X.7    Perou, C.M.8
  • 64
    • 33845904383 scopus 로고    scopus 로고
    • + breast cancer-initiating cells to radiation
    • DOI 10.1093/jnci/djj495
    • Tiffany M Phillips, William H McBride and Frank Pajonk: The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst 98(24), 1777-1785 (2006) (Pubitemid 46017929)
    • (2006) Journal of the National Cancer Institute , vol.98 , Issue.24 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 66
    • 0344845003 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and pathologies
    • DOI 10.1016/j.ceb.2003.10.006
    • Jean Paul Thiery: Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 15(6), 740-746 (2003) (Pubitemid 37487967)
    • (2003) Current Opinion in Cell Biology , vol.15 , Issue.6 , pp. 740-746
    • Thiery, J.P.1
  • 67
    • 77954860302 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the cd44(hi/)cd24 (lo/-) stem cell phenotype in human breast cancer
    • Tony Blick, Honor Hugo, Edwin Widodo, Mark Waltham, Cletus Pinto, Sendurai A Mani, Robert A Weinberg, Richard M Neve, Marc E Lenburg and Erik W Thompson: Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. J Mammary Gland Biol Neoplasia 15(2) 235-252 (2010)
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , Issue.2 , pp. 235-252
    • Blick, T.1    Hugo, H.2    Widodo, E.3    Waltham, M.4    Pinto, C.5    Mani, S.A.6    Weinberg, R.A.7    Neve, R.M.8    Lenburg, M.E.9    Thompson, E.W.10
  • 68
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • DOI 10.1038/nrm1835, PII NRM1835
    • Jean Paul Thiery and Jonathan P Sleeman: Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7(2), 131-142 (2006) (Pubitemid 43278296)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 69
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Kornelia Polyak and Robert A Weinberg: Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9(4), 265-273 (2009)
    • (2009) Nat Rev Cancer , vol.9 , Issue.4 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 70
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Jean Paul Thiery: Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2(6), 442-454 (2002)
    • (2002) Nat Rev Cancer , vol.2 , Issue.6 , pp. 442-454
    • Thiery, J.P.1
  • 72
    • 33846901599 scopus 로고    scopus 로고
    • Snail in the frame of malignant tumor recurrence
    • Bram De Craene and Geert Berx: Snail in the frame of malignant tumor recurrence. Breast Cancer Research 8, 105(2006)
    • (2006) Breast Cancer Research , vol.8 , pp. 105
    • De Craene, B.1    Berx, G.2
  • 73
    • 36849002930 scopus 로고    scopus 로고
    • The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-α
    • DOI 10.1210/me.2007-0293
    • Archana Dhasarathy, Masahiro Kajita and Paul A Wade: The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-Alpha. Mol Endocrinol 21(12), 2907-2918 (2007) (Pubitemid 350223504)
    • (2007) Molecular Endocrinology , vol.21 , Issue.12 , pp. 2907-2918
    • Dhasarathy, A.1    Kajita, M.2    Wade, P.A.3
  • 74
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • DOI 10.1016/j.cell.2004.06.006, PII S0092867404005768
    • Jing Yang, Sendurai A Mani, Joana Liu Donaher, Sridhar Ramaswamy, Raphael A Itzykson, Christophe Come, Pierre Savagner, Inna Gitelman, Andrea Richardson and Robert A Weinberg: Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117(7), 927-939 (2004) (Pubitemid 38798858)
    • (2004) Cell , vol.117 , Issue.7 , pp. 927-939
    • Yang, J.1    Mani, S.A.2    Donaher, J.L.3    Ramaswamy, S.4    Itzykson, R.A.5    Come, C.6    Savagner, P.7    Gitelman, I.8    Richardson, A.9    Weinberg, R.A.10
  • 75
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-Throughput screening
    • Piyush B Gupta, Tamer T Onder and Guozhi Jiang: Identification of selective inhibitors of cancer stem cells by high-Throughput screening. Cell 138(4), 645-659 (2009)
    • (2009) Cell , vol.138 , Issue.4 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3
  • 76
    • 70350236538 scopus 로고    scopus 로고
    • Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission
    • Heather A Hirsch, Dimitrios Iliopoulos, Philip N Tsichlis and Kevin Struhl: Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res 69(19), 7507-7511 (2009)
    • (2009) Cancer Res , vol.69 , Issue.19 , pp. 7507-7511
    • Hirsch, H.A.1    Iliopoulos, D.2    Tsichlis, P.N.3    Struhl, K.4
  • 80
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • DOI 10.1016/j.stem.2007.06.002, PII S1934590907000665
    • Patrick C Hermann, Stephan L Huber, Tanja Herrler, Alexandra Aicher, Joachim W Ellwart, Markus Guba, Christiane J Bruns and Christopher Heeschen. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1(3), 313-323 (2007) (Pubitemid 47355323)
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 81
    • 78751486967 scopus 로고    scopus 로고
    • And avri ben-ze'ev. L1-mediated colon cancer cell metastasis does not require changes in emt and cancer stem cell markers
    • Nancy Gavert, Alessia Vivanti, John Hazin, Thomas Brabletz and Avri Ben-Ze'ev. L1-mediated colon cancer cell metastasis does not require changes in EMT and cancer stem cell markers. Mol Cancer Res 9(1), 14-24 (2011)
    • (2011) Mol Cancer Res , vol.9 , Issue.1 , pp. 14-24
    • Gavert, N.1    Vivanti, A.2    Hazin, J.3    Brabletz, T.4
  • 83
    • 9244241576 scopus 로고    scopus 로고
    • Squire, jane bayani, takuichiro hide, r.Mark henkelman, michael d. Cusimano and peter b dirks: Identification of human brain tumour initiating cells
    • Sheila K Singh, Cynthia Hawkins, Ian D Clarke and A Jeremy. Squire, jane Bayani, Takuichiro Hide, R.Mark Henkelman, Michael D. Cusimano and Peter B Dirks: Identification of human brain tumour initiating cells. Nature 432(7015), 396-401 (2004)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3    Jeremy, A.4
  • 85
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • DOI 10.1038/nature05236, PII NATURE05236
    • Shideng Bao, Qiulian Wu, Roger E McLendon, Yueling Hao, Qing Shi, Anita B Hjelmeland, Mark W Dewhirst, Darell D Bigner and Jeremy N Rich: Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444(7120), 756-760 (2006) (Pubitemid 44949604)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6    Dewhirst, M.W.7    Bigner, D.D.8    Rich, J.N.9
  • 86
    • 84888037015 scopus 로고    scopus 로고
    • http://healthforworld.blogspot.com/2008/11/skincancer.html)
  • 87
    • 84888028373 scopus 로고    scopus 로고
    • http://seer.cancer.gov/statfacts/html/melan.html)
  • 88
    • 39849086504 scopus 로고    scopus 로고
    • Learning the ABCs of melanoma-initiating cells
    • DOI 10.1016/j.ccr.2008.02.015, PII S1535610808000512
    • Susan E Zabierowski and Meenhard Herlyn: Learning the ABCs of melanoma-initiating cells. Cancer Cell 13 (3), 185-187 (2008) (Pubitemid 351318377)
    • (2008) Cancer Cell , vol.13 , Issue.3 , pp. 185-187
    • Zabierowski, S.E.1    Herlyn, M.2
  • 89
    • 78651388751 scopus 로고    scopus 로고
    • Expression of the stem cell markers nestin and cd133 on circulating melanoma cells
    • Alberto Fusi, Uta Reichelt, Antonia Busse, Sebastian Ochsenreither, Anika Rietz, Markus Maisel and Ulrich Keilholz: Expression of the stem cell markers nestin and CD133 on circulating melanoma cells. J Invest Dermatol 131(2), 487-494 (2011)
    • (2011) J Invest Dermatol , vol.131 , Issue.2 , pp. 487-494
    • Fusi, A.1    Reichelt, U.2    Busse, A.3    Ochsenreither, S.4    Rietz, A.5    Maisel, M.6    Keilholz, U.7
  • 90
    • 25844508786 scopus 로고    scopus 로고
    • The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
    • DOI 10.1038/ng1634, PII N1634
    • Piyush B Gupta, Charlotte Kuperwasser, Jean-Philippe Brunet, Sridhar Ramaswamy, Wen-Lin Kuo, Joe W Gray, Stephen P Naber, and Robert A Weinberg: The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet 37(10), 1047-1054 (2005) (Pubitemid 41486656)
    • (2005) Nature Genetics , vol.37 , Issue.10 , pp. 1047-1054
    • Gupta, P.B.1    Kuperwasser, C.2    Brunet, J.-P.3    Ramaswamy, S.4    Kuo, W.-L.5    Gray, J.W.6    Naber, S.P.7    Weinberg, R.A.8
  • 92
    • 78249250559 scopus 로고    scopus 로고
    • Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized
    • Elsa Quintana, Mark Shackleton, Hannah R Foster, Douglas R Fullen, Michael S Sabel, Timothy M Johnson and Sean J Morrison: Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell 18(5), 510-523 (2010)
    • (2010) Cancer Cell , vol.18 , Issue.5 , pp. 510-523
    • Quintana, E.1    Shackleton, M.2    Foster, H.R.3    Fullen, D.R.4    Sabel, M.S.5    Johnson, T.M.6    Morrison, S.J.7
  • 93
    • 75149165632 scopus 로고    scopus 로고
    • Characterization of melanoma cells capable of propagating tumors from a single cell
    • Matthew A Held, David P Curley, David Dankort, Martin McMahon, Viswanathan Muthusamy and Marcus W Bosenberg: Characterization of melanoma cells capable of propagating tumors from a single cell. Cancer Res 70(1), 388-397 (2010)
    • (2010) Cancer Res , vol.70 , Issue.1 , pp. 388-397
    • Held, M.A.1    Curley, D.P.2    Dankort, D.3    McMahon, M.4    Muthusamy, V.5    Bosenberg, M.W.6
  • 95
    • 78349234668 scopus 로고    scopus 로고
    • Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis
    • Ryan Morrison, Stephen M Schleicher, Yunguang Sun, Kenneth J Niermann, Sungjune Kim, Daniel E Spratt, Christine H Chung and Bo Lu: Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis. J Oncol 2011, 941876 (2011)
    • (2011) J Oncol , vol.2011 , pp. 941876
    • Morrison, R.1    Schleicher, S.M.2    Sun, Y.3    Niermann, K.J.4    Kim, S.5    Spratt, D.E.6    Chung, C.H.7    Lu, B.8
  • 96
    • 0037227965 scopus 로고    scopus 로고
    • CD44: From adhesion molecules to signalling regulators
    • DOI 10.1038/nrm1004
    • Helmut Ponta, Larry Sherman and Peter A Herrlich: CD44: from adhesion molecules to signalling regulators. Nat Rev Mol Cell Biol 4(1), 33-45 (2003) (Pubitemid 36077255)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.1 , pp. 33-45
    • Ponta, H.1    Sherman, L.2    Herrlich, P.A.3
  • 98
    • 70350362953 scopus 로고    scopus 로고
    • Hyaluronan-cd44 interaction with protein kinase c(epsilon) promotes oncogenic signaling by the stem cell marker nanog and the production of microrna-21, leading to down-regulation of the tumor suppressor protein pdcd4, anti-Apoptosis, and chemotherapy resistance in breast tumor cells
    • Lilly Y Bourguignon, Christina C Spevak, Gabriel Wong, Weiliang Xia and Eli Gilad: Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-Apoptosis, and chemotherapy resistance in breast tumor cells. J Biol Chem 284(39), 26533-26546 (2009)
    • (2009) J Biol Chem , vol.284 , Issue.39 , pp. 26533-26546
    • Bourguignon, L.Y.1    Spevak, C.C.2    Wong, G.3    Xia, W.4    Gilad, E.5
  • 99
    • 58049201990 scopus 로고    scopus 로고
    • The stem cell-Associated antigen cd133 (prominin-1) is a molecular therapeutic target for metastatic melanoma
    • Germana Rappa, Oystein Fodstad and Aurelio Lorico. The stem cell-Associated antigen CD133 (Prominin-1) is a molecular therapeutic target for metastatic melanoma. Stem Cells 26(12), 3008-1307 (2008)
    • (2008) Stem Cells , vol.26 , Issue.12 , pp. 3008-1307
    • Rappa, G.1    Fodstad, O.2    Lorico, A.3
  • 102
    • 60149084188 scopus 로고    scopus 로고
    • Targeting signal pathways active in cancer stem cells to overcome drug resistance
    • Miaorong She and Xilin Chen: Targeting Signal Pathways active in Cancer Stem Cells to Overcome Drug Resistance. Zhongguo Fei Ai Za Zhi 12(1), 3-7 (2009)
    • (2009) Zhongguo Fei Ai Za Zhi , vol.12 , Issue.1 , pp. 3-7
    • She, M.1    Chen, X.2
  • 104
    • 68749088356 scopus 로고    scopus 로고
    • Notch inhibition and glucocorticoid therapy in t-cell acute lymphoblastic leukemia
    • Pedro J Real and Adolfo A Ferrando: NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia. Leukemia 23(8), 1374-1377 (2009)
    • (2009) Leukemia , vol.23 , Issue.8 , pp. 1374-1377
    • Real, P.J.1    Ferrando, A.A.2
  • 105
    • 36249025636 scopus 로고    scopus 로고
    • Wnt signaling, stem cells, and the cellular origin of breast cancer
    • DOI 10.1007/s12015-007-0025-3, PII SCR32157
    • Charlotta Lindvall, Wen Bu, Bart O Williams and Yi Li: Wnt signaling, stem cells, and the cellular origin of breast cancer. Stem Cell Rev 3(2), 157-168 (2007) (Pubitemid 350129718)
    • (2007) Stem Cell Reviews , vol.3 , Issue.2 , pp. 157-168
    • Lindvall, C.1    Bu, W.2    Williams, B.O.3    Li, Y.4
  • 107
    • 68849083504 scopus 로고    scopus 로고
    • Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of wnt/beta-catenin signaling
    • Chandra P Prasad, Gayatri Rath, Sandeep Mathur, Dinesh Bhatnagar and Ranju Ralhan: Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling. Chem Biol Interact 181(2), 263-271 (2009)
    • (2009) Chem Biol Interact , vol.181 , Issue.2 , pp. 263-271
    • Prasad, C.P.1    Rath, G.2    Mathur, S.3    Bhatnagar, D.4    Ralhan, R.5
  • 108
    • 77958011209 scopus 로고    scopus 로고
    • Curcumin, the golden spice from indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs
    • Atul Goel and Bharat B Aggarwal: Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. Nutr Cancer 62(7), 919-930 (2010)
    • (2010) Nutr Cancer , vol.62 , Issue.7 , pp. 919-930
    • Goel, A.1    Aggarwal, B.B.2
  • 109
    • 33744490370 scopus 로고    scopus 로고
    • Biological effects of curcumin and its role in cancer chemoprevention and therapy
    • Sarvjeet Singh and Ashok Khar: Biological effects of curcumin and its role in cancer chemoprevention and therapy. Anticancer Agents Med Chem 6(3), 259-270 (2006) (Pubitemid 43796643)
    • (2006) Anti-Cancer Agents in Medicinal Chemistry , vol.6 , Issue.3 , pp. 259-270
    • Singh, S.1    Khar, A.2
  • 110
    • 0031860081 scopus 로고    scopus 로고
    • Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
    • DOI 10.1055/s-2006-957450
    • Guido Shoba, David Joy, Thangam Joseph, Mudassir Majeed, Ramaswamy Rajendran and PS Srinivas: Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 64(4), 353-356 (1998) (Pubitemid 28234275)
    • (1998) Planta Medica , vol.64 , Issue.4 , pp. 353-356
    • Shoba, G.1    Joy, D.2    Joseph, T.3    Majeed, M.4    Rajendran, R.5    Srinivas, P.S.S.R.6
  • 112
    • 34447506459 scopus 로고    scopus 로고
    • Modulation of function of three abc drug transporters, pglycoprotein (abcb1), mitoxantrone resistance protein (abcg2) and multidrug resistance protein 1 (abcc1) by tetrahydrocurcumin, a major metabolite of curcumin
    • Pornngarm Limtrakul, Wanida Chearwae, Suneet Shukla, Chada Phisalphong, Suresh V Ambudkar: Modulation of function of three ABC drug transporters, Pglycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. Mol Cell Biochem 296(1-2), 85-95 (2007)
    • (2007) Mol Cell Biochem , vol.296 , Issue.1-2 , pp. 85-95
    • Limtrakul, P.1    Chearwae, W.2    Shukla, S.3    Phisalphong, C.4    Ambudkar, S.V.5
  • 114
    • 77953693899 scopus 로고    scopus 로고
    • Targeting hedgehog-A cancer stem cell pathway
    • Akil A Merchant and William Matsui: Targeting Hedgehog-A cancer stem cell pathway. Clin Cancer Res 16(12), 3130-3140 (2010)
    • (2010) Clin Cancer Res , vol.16 , Issue.12 , pp. 3130-3140
    • Merchant, A.A.1    Matsui, W.2
  • 115
    • 73649145223 scopus 로고    scopus 로고
    • Human colon cancer epithelial cells harbour active hedgehog-gli signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion
    • Frederic Varnat, Arnaud Duquet, Monica Malerba, Marie Zbinden, Christophe Mas, Pascal Gervaz and Altaba Ariel Ruizi: Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion. EMBO Mol Med 1(6-7), 338-351 (2009)
    • (2009) EMBO Mol Med , vol.1 , Issue.6-7 , pp. 338-351
    • Varnat, F.1    Duquet, A.2    Malerba, M.3    Zbinden, M.4    Mas, C.5    Gervaz, P.6    Ruizi, A.A.7
  • 116
    • 0032486433 scopus 로고    scopus 로고
    • Teratogen-mediated inhibition of target tissue response to Shh signaling
    • DOI 10.1126/science.280.5369.1603
    • Michael K Cooper, Jeffrey A Porter, Keith E Young and Philip A Beachy: Teratogen-mediated inhibition of target tissue response to Shh signaling. Science 280(5369), 1603-1607 (1998) (Pubitemid 28277705)
    • (1998) Science , vol.280 , Issue.5369 , pp. 1603-1607
    • Cooper, M.K.1    Porter, J.A.2    Young, K.E.3    Beachy, P.A.4
  • 118
    • 72949103044 scopus 로고    scopus 로고
    • Small-molecule modulators of the sonic hedgehog signaling pathway
    • Benjamin Z Stanton and Lee F Peng: Small-molecule modulators of the Sonic Hedgehog signaling pathway. Mol Biosyst 6(1), 44-54 (2010)
    • (2010) Mol Biosyst , vol.6 , Issue.1 , pp. 44-54
    • Stanton, B.Z.1    Peng, L.F.2
  • 120
    • 79952121979 scopus 로고    scopus 로고
    • Inducible formation of breast cancer stem cells and their dynamic equilibrium with nonstem cancer cells via il6 secretion
    • Dimitrios Iliopoulos, Heather A Hirsch, Guixiang Wang and Kevin Struhl: Inducible formation of breast cancer stem cells and their dynamic equilibrium with nonstem cancer cells via IL6 secretion. Proc Natl Acad Sci U S A 108(4), 1397-1402 (2011)
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.4 , pp. 1397-1402
    • Iliopoulos, D.1    Hirsch, H.A.2    Wang, G.3    Struhl, K.4
  • 122
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • DOI 10.1016/j.ccr.2004.06.022, PII S1535610804002107
    • Yoichi Nagata, Keng-Hsueh Lan, Xiaoyan Zhou, Ming Tan, Franscisco J Esteva, Aysegul A Sahin, Kristine S Klos, Ping Li, Brett P Monia, Nina T Nguyen, Gabriel N Hortobagyi, Mien-Chie Hung and Dihua Yu: PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance inpatients. Cancer Cell 6(2), 117-127 (2004) (Pubitemid 39485684)
    • (2004) Cancer Cell , vol.6 , Issue.2 , pp. 117-127
    • Nagata, Y.1    Lan, K.-H.2    Zhou, X.3    Tan, M.4    Esteva, F.J.5    Sahin, A.A.6    Klos, K.S.7    Li, P.8    Monia, B.P.9    Nguyen, N.T.10    Hortobagyi, G.N.11    Hung, M.-C.12    Yu, D.13


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.