메뉴 건너뛰기




Volumn 4, Issue 1, 2009, Pages

Ets1 induces dysplastic changes when expressed in terminally-differentiating squamous epidermal cells

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE 3; TRANSCRIPTION FACTOR ETS 1; MMP13 PROTEIN, MOUSE;

EID: 58449096418     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004179     Document Type: Article
Times cited : (29)

References (75)
  • 1
    • 33748881058 scopus 로고    scopus 로고
    • Molecular biology of malignant melanoma and other cutaneous tumors
    • Pons M, Quintanilla M (2006) Molecular biology of malignant melanoma and other cutaneous tumors. Clin Transl Oncol 8: 466-474.
    • (2006) Clin Transl Oncol , vol.8 , pp. 466-474
    • Pons, M.1    Quintanilla, M.2
  • 2
    • 14044257121 scopus 로고    scopus 로고
    • Ultraviolet radiation and skin cancer: Molecular mechanisms
    • Hussein MR (2005) Ultraviolet radiation and skin cancer: molecular mechanisms. J Cutan Pathol 32: 191-205.
    • (2005) J Cutan Pathol , vol.32 , pp. 191-205
    • Hussein, M.R.1
  • 3
    • 1642440141 scopus 로고    scopus 로고
    • Ets-1 immunohistochemical expression in non-melanoma skin carcinoma
    • Keehn CA, Smoller BR, Morgan MB (2004) Ets-1 immunohistochemical expression in non-melanoma skin carcinoma. J Cutan Pathol 31: 8-13.
    • (2004) J Cutan Pathol , vol.31 , pp. 8-13
    • Keehn, C.A.1    Smoller, B.R.2    Morgan, M.B.3
  • 4
    • 0032818740 scopus 로고    scopus 로고
    • Ets-1: A plausible marker of invasive potential and lymph node metastasis in human oral squamous cell carcinomas
    • Pande P, Mathur M, Shukla NK, Ralhan R (1999) Ets-1: a plausible marker of invasive potential and lymph node metastasis in human oral squamous cell carcinomas. J Pathol 189: 40-45.
    • (1999) J Pathol , vol.189 , pp. 40-45
    • Pande, P.1    Mathur, M.2    Shukla, N.K.3    Ralhan, R.4
  • 5
    • 0034668091 scopus 로고    scopus 로고
    • Expression of ets-1 transcription factor is correlated with penetrating tumor progression in patients with squamous cell carcinoma of the esophagus
    • Saeki H, Kuwano H, Kawaguchi H, Ohno S, Sugimachi K (2000) Expression of ets-1 transcription factor is correlated with penetrating tumor progression in patients with squamous cell carcinoma of the esophagus. Cancer 89: 1670-1676.
    • (2000) Cancer , vol.89 , pp. 1670-1676
    • Saeki, H.1    Kuwano, H.2    Kawaguchi, H.3    Ohno, S.4    Sugimachi, K.5
  • 6
    • 0041662036 scopus 로고    scopus 로고
    • Ets-1 and VEGF expression correlates with tumor angiogenesis, lymph node metastasis, and patient survival in esophageal squamous cell carcinoma
    • Mukherjee T, Kumar A, Mathur M, Chattopadhyay TK, Ralhan R (2003) Ets-1 and VEGF expression correlates with tumor angiogenesis, lymph node metastasis, and patient survival in esophageal squamous cell carcinoma. J Cancer Res Clin Oncol 129: 430-436.
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 430-436
    • Mukherjee, T.1    Kumar, A.2    Mathur, M.3    Chattopadhyay, T.K.4    Ralhan, R.5
  • 8
    • 33746090453 scopus 로고    scopus 로고
    • Prognostic value of cell motility activation factors in patients with tongue squamous cell carcinoma
    • Endo K, Shirai A, Furukawa M, Yoshizaki T (2006) Prognostic value of cell motility activation factors in patients with tongue squamous cell carcinoma. Hum Pathol 37: 1111-1116.
    • (2006) Hum Pathol , vol.37 , pp. 1111-1116
    • Endo, K.1    Shirai, A.2    Furukawa, M.3    Yoshizaki, T.4
  • 9
    • 34547731920 scopus 로고    scopus 로고
    • Diabetes increases both N-ras and ets-1 expression during rat oral oncogenesis resulting in enhanced cell proliferation and metastatic potential
    • Vairaktaris E, Goutzanis L, Kalokerinos G, Yannopoulos A, Yapijakis C, et al. (2007) Diabetes increases both N-ras and ets-1 expression during rat oral oncogenesis resulting in enhanced cell proliferation and metastatic potential. In Vivo 21: 615-621.
    • (2007) In Vivo , vol.21 , pp. 615-621
    • Vairaktaris, E.1    Goutzanis, L.2    Kalokerinos, G.3    Yannopoulos, A.4    Yapijakis, C.5
  • 11
    • 0025809504 scopus 로고
    • The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins
    • Wasylyk C, Gutman A, Nicholson R, Wasylyk B (1991) The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins. Embo J 10: 1127-1134.
    • (1991) Embo J , vol.10 , pp. 1127-1134
    • Wasylyk, C.1    Gutman, A.2    Nicholson, R.3    Wasylyk, B.4
  • 12
    • 0030873346 scopus 로고    scopus 로고
    • Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors
    • Westermarck J, Seth A, Kahari VM (1997) Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors. Oncogene 14: 2651-2660.
    • (1997) Oncogene , vol.14 , pp. 2651-2660
    • Westermarck, J.1    Seth, A.2    Kahari, V.M.3
  • 13
    • 0032479139 scopus 로고    scopus 로고
    • The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor
    • Watabe T, Yoshida K, Shindoh M, Kaya M, Fujikawa K, et al. (1998) The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor. Int J Cancer 77: 128-137.
    • (1998) Int J Cancer , vol.77 , pp. 128-137
    • Watabe, T.1    Yoshida, K.2    Shindoh, M.3    Kaya, M.4    Fujikawa, K.5
  • 14
    • 19044367561 scopus 로고    scopus 로고
    • Baillat D, Begue A, Stehelin D, Aumercier M (2002) ETS-1 Transcription Factor Binds Cooperatively to the Palindromic Head to Head ETS-binding Sites of the Stromelysin-1 Promoter by Counteracting Autoinhibition. J Biol Chem 277: 29386-29398.
    • Baillat D, Begue A, Stehelin D, Aumercier M (2002) ETS-1 Transcription Factor Binds Cooperatively to the Palindromic Head to Head ETS-binding Sites of the Stromelysin-1 Promoter by Counteracting Autoinhibition. J Biol Chem 277: 29386-29398.
  • 15
    • 0036014940 scopus 로고    scopus 로고
    • Transcription factor Ets-1 regulates gelatinase a gene expression in mesangial cells
    • Reisdorff J, En-Nia A, Stefanidis I, Floege J, Lovett DH, et al. (2002) Transcription factor Ets-1 regulates gelatinase a gene expression in mesangial cells. J Am Soc Nephrol 13: 1568-1578.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1568-1578
    • Reisdorff, J.1    En-Nia, A.2    Stefanidis, I.3    Floege, J.4    Lovett, D.H.5
  • 16
    • 0033868210 scopus 로고    scopus 로고
    • Parathyroid hormone induces rat interstitial collagenase mRNA through Ets-1 facilitated by cyclic AMP response element-binding protein and Ca(2+)/calmodulin-dependent protein kinase II in osteoblastic cells
    • Quinn CO, Rajakumar RA, Agapova OA (2000) Parathyroid hormone induces rat interstitial collagenase mRNA through Ets-1 facilitated by cyclic AMP response element-binding protein and Ca(2+)/calmodulin-dependent protein kinase II in osteoblastic cells. J Mol Endocrinol 25: 73-84.
    • (2000) J Mol Endocrinol , vol.25 , pp. 73-84
    • Quinn, C.O.1    Rajakumar, R.A.2    Agapova, O.A.3
  • 17
    • 0034644506 scopus 로고    scopus 로고
    • Opposing effects of Ras on p53: Transcriptional activation of mdm2 and induction of p19ARF
    • Ries S, Biederer C, Woods D, Shifman O, Shirasawa S, et al. (2000) Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF. Cell 103: 321-330.
    • (2000) Cell , vol.103 , pp. 321-330
    • Ries, S.1    Biederer, C.2    Woods, D.3    Shifman, O.4    Shirasawa, S.5
  • 18
    • 0028009754 scopus 로고
    • Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1
    • Roussel MF, Davis JN, Cleveland JL, Ghysdael J, Hiebert SW (1994) Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1. Oncogene 9: 405-415.
    • (1994) Oncogene , vol.9 , pp. 405-415
    • Roussel, M.F.1    Davis, J.N.2    Cleveland, J.L.3    Ghysdael, J.4    Hiebert, S.W.5
  • 19
    • 0028047598 scopus 로고
    • junB promoter regulation: Ras mediated transactivation by c-Ets-1 and c-Ets-2
    • Coffer P, de Jonge M, Mettouchi A, Binetruy B, Ghysdael J, et al. (1994) junB promoter regulation: Ras mediated transactivation by c-Ets-1 and c-Ets-2. Oncogene 9: 911-921.
    • (1994) Oncogene , vol.9 , pp. 911-921
    • Coffer, P.1    de Jonge, M.2    Mettouchi, A.3    Binetruy, B.4    Ghysdael, J.5
  • 20
    • 0035931859 scopus 로고    scopus 로고
    • Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
    • Ohtani N, Zebedee Z, Huot TJ, Stinson JA, Sugimoto M, et al. (2001) Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Nature 409: 1067-1070.
    • (2001) Nature , vol.409 , pp. 1067-1070
    • Ohtani, N.1    Zebedee, Z.2    Huot, T.J.3    Stinson, J.A.4    Sugimoto, M.5
  • 21
    • 0042346348 scopus 로고    scopus 로고
    • Zhang C, Kavurma MM, Lai A, Khachigian LM (2003) Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/ Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF/Cip1 promoter. J Biol Chem 278: 27903-27909.
    • Zhang C, Kavurma MM, Lai A, Khachigian LM (2003) Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/ Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF/Cip1 promoter. J Biol Chem 278: 27903-27909.
  • 22
    • 12344334604 scopus 로고    scopus 로고
    • Isolation and characterization of the human Cdc2L1 gene promoter
    • Kahle A, Feng Y, M AN (2005) Isolation and characterization of the human Cdc2L1 gene promoter. Gene 344: 53-60.
    • (2005) Gene , vol.344 , pp. 53-60
    • Kahle, A.1    Feng, Y.2    AN, M.3
  • 23
    • 0034628443 scopus 로고    scopus 로고
    • EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes
    • Li R, Pei H, Watson DK, Papas TS (2000) EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes. Oncogene 19: 745-753.
    • (2000) Oncogene , vol.19 , pp. 745-753
    • Li, R.1    Pei, H.2    Watson, D.K.3    Papas, T.S.4
  • 25
    • 0032855810 scopus 로고    scopus 로고
    • Regulation of the human stress response gene GADD153 expression: Role of ETS1 and FLI-1 gene products
    • Seth A, Giunta S, Franceschil C, Kola I, Venanzoni MC (1999) Regulation of the human stress response gene GADD153 expression: role of ETS1 and FLI-1 gene products. Cell Death Differ 6: 902-907.
    • (1999) Cell Death Differ , vol.6 , pp. 902-907
    • Seth, A.1    Giunta, S.2    Franceschil, C.3    Kola, I.4    Venanzoni, M.C.5
  • 26
    • 0029883919 scopus 로고    scopus 로고
    • ETS1 and ETS2 in p53 regulation: Spatial separation of ETS binding sites (EBS) modulate protein: DNA interaction
    • Venanzoni MC, Robinson LR, Hodge DR, Kola I, Seth A (1996) ETS1 and ETS2 in p53 regulation: spatial separation of ETS binding sites (EBS) modulate protein: DNA interaction. Oncogene 12: 1199-1204.
    • (1996) Oncogene , vol.12 , pp. 1199-1204
    • Venanzoni, M.C.1    Robinson, L.R.2    Hodge, D.R.3    Kola, I.4    Seth, A.5
  • 27
    • 12344277471 scopus 로고    scopus 로고
    • Matrix metalloproteinase 1 gene polymorphism as a prognostic predictor of invasive cervical cancer
    • Lai HC, Chu CM, Lin YW, Chang CC, Nieh S, et al. (2005) Matrix metalloproteinase 1 gene polymorphism as a prognostic predictor of invasive cervical cancer. Gynecol Oncol 96: 314-319.
    • (2005) Gynecol Oncol , vol.96 , pp. 314-319
    • Lai, H.C.1    Chu, C.M.2    Lin, Y.W.3    Chang, C.C.4    Nieh, S.5
  • 30
    • 0035914335 scopus 로고    scopus 로고
    • Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1
    • Sampath J, Sun D, Kidd VJ, Grenet J, Gandhi A, et al. (2001) Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1. J Biol Chem 276: 39359-39367.
    • (2001) J Biol Chem , vol.276 , pp. 39359-39367
    • Sampath, J.1    Sun, D.2    Kidd, V.J.3    Grenet, J.4    Gandhi, A.5
  • 31
    • 0036683054 scopus 로고    scopus 로고
    • Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells
    • Xu D, Wilson TJ, Chan D, De Luca E, Zhou J, et al. (2002) Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells. Embo J 21: 4081-4093.
    • (2002) Embo J , vol.21 , pp. 4081-4093
    • Xu, D.1    Wilson, T.J.2    Chan, D.3    De Luca, E.4    Zhou, J.5
  • 32
    • 0344010664 scopus 로고    scopus 로고
    • Tumor suppressor p53 inhibits transcriptional activation of invasion gene thromboxane synthase mediated by the proto-oncogenic factor ets-1
    • Kim E, Gunther W, Yoshizato K, Meissner H, Zapf S, et al. (2003) Tumor suppressor p53 inhibits transcriptional activation of invasion gene thromboxane synthase mediated by the proto-oncogenic factor ets-1. Oncogene 22: 7716-7727.
    • (2003) Oncogene , vol.22 , pp. 7716-7727
    • Kim, E.1    Gunther, W.2    Yoshizato, K.3    Meissner, H.4    Zapf, S.5
  • 33
    • 10644225068 scopus 로고    scopus 로고
    • Identification and characterization of the IKKalpha promoter: Positive and negative regulation by ETS-1 and p53, respectively
    • Gu L, Zhu N, Findley HW, Woods WG, Zhou M (2004) Identification and characterization of the IKKalpha promoter: positive and negative regulation by ETS-1 and p53, respectively. J Biol Chem 279: 52141-52149.
    • (2004) J Biol Chem , vol.279 , pp. 52141-52149
    • Gu, L.1    Zhu, N.2    Findley, H.W.3    Woods, W.G.4    Zhou, M.5
  • 34
    • 41949118611 scopus 로고    scopus 로고
    • Inhibition of basal activity of c-jun-NH2-terminal kinase (JNK) represses the expression of presenilin-1 by a p53-dependent mechanism
    • Lee S, Das HK (2008) Inhibition of basal activity of c-jun-NH2-terminal kinase (JNK) represses the expression of presenilin-1 by a p53-dependent mechanism. Brain Res 1207: 19-31.
    • (2008) Brain Res , vol.1207 , pp. 19-31
    • Lee, S.1    Das, H.K.2
  • 35
    • 0028225215 scopus 로고
    • Differential expression of ets-1 and ets-2 proto-oncogenes during murine embryogenesis
    • Maroulakou IG, Papas TS, Green JE (1994) Differential expression of ets-1 and ets-2 proto-oncogenes during murine embryogenesis. Oncogene 9: 1551-1565.
    • (1994) Oncogene , vol.9 , pp. 1551-1565
    • Maroulakou, I.G.1    Papas, T.S.2    Green, J.E.3
  • 36
  • 37
    • 3242671305 scopus 로고    scopus 로고
    • Tetracycline-regulated transactivators driven by the involucrin promoter to achieve epidermal conditional gene expression
    • Jaubert J, Patel S, Cheng J, Segre JA (2004) Tetracycline-regulated transactivators driven by the involucrin promoter to achieve epidermal conditional gene expression. J Invest Dermatol 123: 313-318.
    • (2004) J Invest Dermatol , vol.123 , pp. 313-318
    • Jaubert, J.1    Patel, S.2    Cheng, J.3    Segre, J.A.4
  • 38
    • 34247511981 scopus 로고    scopus 로고
    • p63 Is essential for the proliferative potential of stem cells in stratified epithelia
    • Senoo M, Pinto F, Crum CP, McKeon F (2007) p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 129: 523-536.
    • (2007) Cell , vol.129 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 39
    • 0033372016 scopus 로고    scopus 로고
    • Association of p63 with proliferative potential in normal and neoplastic human keratinocytes
    • Parsa R, Yang A, McKeon F, Green H (1999) Association of p63 with proliferative potential in normal and neoplastic human keratinocytes. J Invest Dermatol 113: 1099-1105.
    • (1999) J Invest Dermatol , vol.113 , pp. 1099-1105
    • Parsa, R.1    Yang, A.2    McKeon, F.3    Green, H.4
  • 41
    • 33747872417 scopus 로고    scopus 로고
    • Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis
    • Barbieri CE, Tang LJ, Brown KA, Pietenpol JA (2006) Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis. Cancer Res 66: 7589-7597.
    • (2006) Cancer Res , vol.66 , pp. 7589-7597
    • Barbieri, C.E.1    Tang, L.J.2    Brown, K.A.3    Pietenpol, J.A.4
  • 42
    • 20044379201 scopus 로고    scopus 로고
    • p63 overexpression associates with poor prognosis in head and neck squamous cell carcinoma
    • Lo Muzio L, Santarelli A, Caltabiano R, Rubini C, Pieramici T, et al. (2005) p63 overexpression associates with poor prognosis in head and neck squamous cell carcinoma. Hum Pathol 36: 187-194.
    • (2005) Hum Pathol , vol.36 , pp. 187-194
    • Lo Muzio, L.1    Santarelli, A.2    Caltabiano, R.3    Rubini, C.4    Pieramici, T.5
  • 43
    • 15244338619 scopus 로고    scopus 로고
    • Collagenases in cancer
    • Ala-aho R, Kahari VM (2005) Collagenases in cancer. Biochimie 87: 273-286.
    • (2005) Biochimie , vol.87 , pp. 273-286
    • Ala-aho, R.1    Kahari, V.M.2
  • 44
    • 31144457377 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase (MMP)-2, MMP-9, MMP-13, and MT1-MMP in skin tumors of human papillomavirus type 8 transgenic mice
    • Akgul B, Pfefferle R, Marcuzzi GP, Zigrino P, Krieg T, et al. (2006) Expression of matrix metalloproteinase (MMP)-2, MMP-9, MMP-13, and MT1-MMP in skin tumors of human papillomavirus type 8 transgenic mice. Exp Dermatol 15: 35-42.
    • (2006) Exp Dermatol , vol.15 , pp. 35-42
    • Akgul, B.1    Pfefferle, R.2    Marcuzzi, G.P.3    Zigrino, P.4    Krieg, T.5
  • 45
    • 33644639340 scopus 로고    scopus 로고
    • Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice
    • Hartenstein B, Dittrich BT, Stickens D, Heyer B, Vu TH, et al. (2006) Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice. J Invest Dermatol 126: 486-496.
    • (2006) J Invest Dermatol , vol.126 , pp. 486-496
    • Hartenstein, B.1    Dittrich, B.T.2    Stickens, D.3    Heyer, B.4    Vu, T.H.5
  • 46
    • 17644393522 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds
    • Impola U, Jeskanen L, Ravanti L, Syrjanen S, Baldursson B, et al. (2005) Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds. Br J Dermatol 152: 720-726.
    • (2005) Br J Dermatol , vol.152 , pp. 720-726
    • Impola, U.1    Jeskanen, L.2    Ravanti, L.3    Syrjanen, S.4    Baldursson, B.5
  • 47
    • 0030843734 scopus 로고    scopus 로고
    • Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck
    • Johansson N, Airola K, Grenman R, Kariniemi AL, Saarialho-Kere U, et al. (1997) Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck. Am J Pathol 151: 499-508.
    • (1997) Am J Pathol , vol.151 , pp. 499-508
    • Johansson, N.1    Airola, K.2    Grenman, R.3    Kariniemi, A.L.4    Saarialho-Kere, U.5
  • 48
    • 0036167349 scopus 로고    scopus 로고
    • Real-time visualization of MMP-13 promoter activity in transgenic mice
    • Wu N, Opalenik S, Liu J, Jansen ED, Giro MG, et al. (2002) Real-time visualization of MMP-13 promoter activity in transgenic mice. Matrix Biol 21: 149-161.
    • (2002) Matrix Biol , vol.21 , pp. 149-161
    • Wu, N.1    Opalenik, S.2    Liu, J.3    Jansen, E.D.4    Giro, M.G.5
  • 49
    • 33144469825 scopus 로고    scopus 로고
    • Association between high collagenase-3 expression levels and poor prognosis in patients with head and neck cancer
    • Luukkaa M, Vihinen P, Kronqvist P, Vahlberg T, Pyrhonen S, et al. (2006) Association between high collagenase-3 expression levels and poor prognosis in patients with head and neck cancer. Head Neck 28: 225-234.
    • (2006) Head Neck , vol.28 , pp. 225-234
    • Luukkaa, M.1    Vihinen, P.2    Kronqvist, P.3    Vahlberg, T.4    Pyrhonen, S.5
  • 50
    • 0041806467 scopus 로고    scopus 로고
    • Expression of MMP-2, -9 and -13 in cell lines and fresh biopsies of squamous cell carcinomas of the upper aerodigestive tract
    • Dunne AA, Sesterhenn A, Gerisch A, Teymoortash A, Kuropkat C, et al. (2003) Expression of MMP-2, -9 and -13 in cell lines and fresh biopsies of squamous cell carcinomas of the upper aerodigestive tract. Anticancer Res 23: 2233-2239.
    • (2003) Anticancer Res , vol.23 , pp. 2233-2239
    • Dunne, A.A.1    Sesterhenn, A.2    Gerisch, A.3    Teymoortash, A.4    Kuropkat, C.5
  • 51
    • 2942529276 scopus 로고    scopus 로고
    • The biology of the Ets1 proto-oncogene
    • Dittmer J (2003) The biology of the Ets1 proto-oncogene. Mol Cancer 2: 29.
    • (2003) Mol Cancer , vol.2 , pp. 29
    • Dittmer, J.1
  • 52
    • 23944489424 scopus 로고    scopus 로고
    • Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation
    • List K, Szabo R, Molinolo A, Sriuranpong V, Redeye V, et al. (2005) Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation. Genes Dev 19: 1934-1950.
    • (2005) Genes Dev , vol.19 , pp. 1934-1950
    • List, K.1    Szabo, R.2    Molinolo, A.3    Sriuranpong, V.4    Redeye, V.5
  • 53
    • 0036157925 scopus 로고    scopus 로고
    • Development of ichthyosiform skin compensates for defective permeability barrier function in mice lacking transglutaminase 1
    • Kuramoto N, Takizawa T, Matsuki M, Morioka H, Robinson JM, et al. (2002) Development of ichthyosiform skin compensates for defective permeability barrier function in mice lacking transglutaminase 1. J Clin Invest 109: 243-250.
    • (2002) J Clin Invest , vol.109 , pp. 243-250
    • Kuramoto, N.1    Takizawa, T.2    Matsuki, M.3    Morioka, H.4    Robinson, J.M.5
  • 54
    • 0038819656 scopus 로고    scopus 로고
    • Contribution of stem cells and differentiated cells to epidermal tumours
    • Owens DM, Watt FM (2003) Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer 3: 444-451.
    • (2003) Nat Rev Cancer , vol.3 , pp. 444-451
    • Owens, D.M.1    Watt, F.M.2
  • 55
    • 0038819885 scopus 로고    scopus 로고
    • Stem-cell hierarchy in skin cancer
    • Perez-Losada J, Balmain A (2003) Stem-cell hierarchy in skin cancer. Nat Rev Cancer 3: 434-443.
    • (2003) Nat Rev Cancer , vol.3 , pp. 434-443
    • Perez-Losada, J.1    Balmain, A.2
  • 56
    • 10844223748 scopus 로고    scopus 로고
    • Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis
    • Vitale-Cross L, Amornphimoltham P, Fisher G, Molinolo AA, Gutkind JS (2004) Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis. Cancer Res 64: 8804-8807.
    • (2004) Cancer Res , vol.64 , pp. 8804-8807
    • Vitale-Cross, L.1    Amornphimoltham, P.2    Fisher, G.3    Molinolo, A.A.4    Gutkind, J.S.5
  • 57
    • 0033001621 scopus 로고    scopus 로고
    • Reversible activation of c-Myc in skin: Induction of a complex neoplastic phenotype by a single oncogenic lesion
    • Pelengaris S, Littlewood T, Khan M, Elia G, Evan G (1999) Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Mol Cell 3: 565-577.
    • (1999) Mol Cell , vol.3 , pp. 565-577
    • Pelengaris, S.1    Littlewood, T.2    Khan, M.3    Elia, G.4    Evan, G.5
  • 58
    • 0035901594 scopus 로고    scopus 로고
    • c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
    • Arnold I, Watt FM (2001) c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol 11: 558-568.
    • (2001) Curr Biol , vol.11 , pp. 558-568
    • Arnold, I.1    Watt, F.M.2
  • 59
    • 21644479378 scopus 로고    scopus 로고
    • Ectopic expression of c-Myc in the skin affects the hair growth cycle and causes an enlargement of the sebaceous gland
    • Bull JJ, Pelengaris S, Hendrix S, Chronnell CM, Khan M, et al. (2005) Ectopic expression of c-Myc in the skin affects the hair growth cycle and causes an enlargement of the sebaceous gland. Br J Dermatol 152: 1125-1133.
    • (2005) Br J Dermatol , vol.152 , pp. 1125-1133
    • Bull, J.J.1    Pelengaris, S.2    Hendrix, S.3    Chronnell, C.M.4    Khan, M.5
  • 60
    • 0029150852 scopus 로고
    • c-fos is required for malignant progression of skin tumors
    • Saez E, Rutberg SE, Mueller E, Oppenheim H, Smoluk J, et al. (1995) c-fos is required for malignant progression of skin tumors. Cell 82: 721-732.
    • (1995) Cell , vol.82 , pp. 721-732
    • Saez, E.1    Rutberg, S.E.2    Mueller, E.3    Oppenheim, H.4    Smoluk, J.5
  • 61
    • 0029998491 scopus 로고    scopus 로고
    • Cellular transformation and malignancy induced by ras require c-jun
    • Johnson R, Spiegelman B, Hanahan D, Wisdom R (1996) Cellular transformation and malignancy induced by ras require c-jun. Mol Cell Biol 16: 4504-4511.
    • (1996) Mol Cell Biol , vol.16 , pp. 4504-4511
    • Johnson, R.1    Spiegelman, B.2    Hanahan, D.3    Wisdom, R.4
  • 62
    • 0036063760 scopus 로고    scopus 로고
    • The structure, regulation, and function of human matrix metalloproteinase-13
    • Leeman MF, Curran S, Murray GI (2002) The structure, regulation, and function of human matrix metalloproteinase-13. Crit Rev Biochem Mol Biol 37: 149-166.
    • (2002) Crit Rev Biochem Mol Biol , vol.37 , pp. 149-166
    • Leeman, M.F.1    Curran, S.2    Murray, G.I.3
  • 63
    • 0031426654 scopus 로고    scopus 로고
    • Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells
    • Lochter A, Galosy S, Muschler J, Freedman N, Werb Z, et al. (1997) Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J Cell Biol 139: 1861-1872.
    • (1997) J Cell Biol , vol.139 , pp. 1861-1872
    • Lochter, A.1    Galosy, S.2    Muschler, J.3    Freedman, N.4    Werb, Z.5
  • 64
    • 33947219432 scopus 로고    scopus 로고
    • Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells
    • Symowicz J, Adley BP, Gleason KJ, Johnson JJ, Ghosh S, et al. (2007) Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells. Cancer Res 67: 2030-2039.
    • (2007) Cancer Res , vol.67 , pp. 2030-2039
    • Symowicz, J.1    Adley, B.P.2    Gleason, K.J.3    Johnson, J.J.4    Ghosh, S.5
  • 65
    • 34347261026 scopus 로고    scopus 로고
    • Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells
    • Lee KH, Choi EY, Hyun MS, Jang BI, Kim TN, et al. (2007) Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells. Eur Surg Res 39: 208-215.
    • (2007) Eur Surg Res , vol.39 , pp. 208-215
    • Lee, K.H.1    Choi, E.Y.2    Hyun, M.S.3    Jang, B.I.4    Kim, T.N.5
  • 66
    • 34247380782 scopus 로고    scopus 로고
    • Metalloproteinase 9 is the outer executioner of desmoglein 3 in apoptotic keratinocytes
    • Cirillo N, Femiano F, Gombos F, Lanza A (2007) Metalloproteinase 9 is the outer executioner of desmoglein 3 in apoptotic keratinocytes. Oral Dis 13: 341-345.
    • (2007) Oral Dis , vol.13 , pp. 341-345
    • Cirillo, N.1    Femiano, F.2    Gombos, F.3    Lanza, A.4
  • 67
    • 0034787354 scopus 로고    scopus 로고
    • Matrilysin mediates extracellular cleavage of E-cadherin from prostate cancer cells: A key mechanism in hepatocyte growth factor/scatter factor-induced cell-cell dissociation and in vitro invasion
    • Davies G, Jiang WG, Mason MD (2001) Matrilysin mediates extracellular cleavage of E-cadherin from prostate cancer cells: a key mechanism in hepatocyte growth factor/scatter factor-induced cell-cell dissociation and in vitro invasion. Clin Cancer Res 7: 3289-3297.
    • (2001) Clin Cancer Res , vol.7 , pp. 3289-3297
    • Davies, G.1    Jiang, W.G.2    Mason, M.D.3
  • 69
    • 0029122808 scopus 로고
    • Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis
    • D'Armiento J, DiColandrea T, Dalal SS, Okada Y, Huang MT, et al. (1995) Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis. Mol Cell Biol 15: 5732-5739.
    • (1995) Mol Cell Biol , vol.15 , pp. 5732-5739
    • D'Armiento, J.1    DiColandrea, T.2    Dalal, S.S.3    Okada, Y.4    Huang, M.T.5
  • 70
    • 0032403129 scopus 로고    scopus 로고
    • The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis
    • Rudolph-Owen LA, Chan R, Muller WJ, Matrisian LM (1998) The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis. Cancer Res 58: 5500-5506.
    • (1998) Cancer Res , vol.58 , pp. 5500-5506
    • Rudolph-Owen, L.A.1    Chan, R.2    Muller, W.J.3    Matrisian, L.M.4
  • 71
    • 0034696350 scopus 로고    scopus 로고
    • The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter
    • Sternlicht MD, Bissell MJ, Werb Z (2000) The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter. Oncogene 19: 1102-1113.
    • (2000) Oncogene , vol.19 , pp. 1102-1113
    • Sternlicht, M.D.1    Bissell, M.J.2    Werb, Z.3
  • 72
    • 0035110730 scopus 로고    scopus 로고
    • Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice
    • Ha HY, Moon HB, Nam MS, Lee JW, Ryoo ZY, et al. (2001) Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice. Cancer Res 61: 984-990.
    • (2001) Cancer Res , vol.61 , pp. 984-990
    • Ha, H.Y.1    Moon, H.B.2    Nam, M.S.3    Lee, J.W.4    Ryoo, Z.Y.5
  • 73
    • 33750315799 scopus 로고    scopus 로고
    • Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis
    • Jin X, Yagi M, Akiyama N, Hirosaki T, Higashi S, et al. (2006) Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis. Cancer Sci 97: 1327-1334.
    • (2006) Cancer Sci , vol.97 , pp. 1327-1334
    • Jin, X.1    Yagi, M.2    Akiyama, N.3    Hirosaki, T.4    Higashi, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.