Plant polyphenols attenuate hepatic injury after hemorrhage/resuscitation by inhibition of apoptosis, oxidative stress, and inflammation via NF-kappaB in rats

European Journal of Nutrition

Volumn 51, Issue 3, 2012, Pages 311-321

  Relja, Borna ^a   Töttel, Eva ^a   Breig, Lara ^a   Henrich, Dirk ^a   Schneider, Heinz ^b   Marzi, Ingo ^a   Lehnert, Mark ^a  

^a GOETHE UNIVERSITY   (Germany)

^b HealthEcon Ltd   (Switzerland)

Author keywords

Apoptosis; Green tea extract; Hemorrhagic shock; In vivo; Liver; NF kappaB; Plant polyphenols

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; ALANINE AMINOTRANSFERASE; CASPASE 8; CYTOKINE; GREEN TEA EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MESSENGER RNA; POLYPHENOL; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DNA FRAGMENTATION; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; INFLAMMATION; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER INJURY; LIVER NECROSIS; NITROSATIVE STRESS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; WESTERN BLOTTING;

ACUTE DISEASE; ALANINE TRANSAMINASE; ALDEHYDES; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 8; FEMALE; GENE EXPRESSION REGULATION; HEMORRHAGE; INFLAMMATION; INTERLEUKIN-6; L-LACTATE DEHYDROGENASE; LIVER; NF-KAPPA B; OXIDATIVE STRESS; PLANT EXTRACTS; POLYPHENOLS; RATS; RATS, INBRED LEW; RESUSCITATION; RNA; TEA; TYROSINE;

CAMELLIA SINENSIS; RATTUS;

EID: 84860690427     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-011-0216-1     Document Type: Article

References (59)

1. Peden M, Hyder A (2002) Road traffic injuries are a global public health problem. BMJ 324(7346):1153 (Pubitemid 34518114)
2. Mock C, Joshipura M, Goosen J, Maier R (2006) Overview of the essential trauma care project. World J Surg 30(6):919-929 (Pubitemid 43824397)
3. Baue AE, Durham R, Faist E (1998) Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): are we winning the battle? Shock 10(2):79-89 (Pubitemid 128463838)
4. Bogner V, Keil L, Kanz KG, Kirchhoff C, Leidel BA, Mutschler W, Biberthaler P (2009) Very early posttraumatic serum alterations are significantly associated to initial massive RBC substitution, injury severity, multiple organ failure and adverse clinical outcome in multiple injured patients. Eur J Med Res 14(7):284-291
5. Moore FA, Sauaia A, Moore EE, Haenel JB, Burch JM, Lezotte DC (1996) Postinjury multiple organ failure: a bimodal phenomenon. J Trauma 40(4):501-510 (Pubitemid 126425001)
6. Hietbrink F, Koenderman L, Rijkers G, Leenen L (2006) Trauma: the role of the innate immune system. World J Emerg Surg 1:15
7. Partrick DA, Moore FA, Moore EE, Barnett CC Jr, Silliman CC (1996) Neutrophil priming and activation in the pathogenesis of postinjury multiple organ failure. New Horiz 4(2):194-210 (Pubitemid 26171429)
8. Botha AJ, Moore FA, Moore EE, Kim FJ, Banerjee A, Peterson VM (1995) Postinjury neutrophil priming and activation: an early vulnerable window. Surgery 118(2):358-364
9. Redl H, Gasser H, Schlag G, Marzi I (1993) Involvement of oxygen radicals in shock related cell injury. Br Med Bull 49(3):556-565 (Pubitemid 23243829)
10. Passos JF, Saretzki G, von Zglinicki ZT (2007) DNA damage in telomeres and mitochondria during cellular senescence: is there a connection? Nucleic Acids Res 35(22):7505-7513
11. Akgur FM, Brown MF, Zibari GB, McDonald JC, Epstein CJ, Ross CR, Granger DN (2000) Role of superoxide in hemorrhagic shock-induced P-selectin expression. Am J Physiol Heart Circ Physiol 279(2):H791-H797
12. Relja B, Schwestka B, Lee VS, Henrich D, Czerny C, Borsello T, Marzi I, Lehnert M (2009) Inhibition of c-Jun. N-terminal kinase after hemorrhage but before resuscitation mitigates hepatic damage and inflammatory response in male rats. Shock 32(5):509-516
13. Meng ZH, Dyer K, Billiar TR, Tweardy DJ (2001) Essential role for IL-6 in postresuscitation inflammation in hemorrhagic shock. Am J Physiol Cell Physiol 280(2):C343-C351
14. Lluis JM, Llacuna L, von Montfort MC, Barcena C, Enrich C, Morales A, Fernandez-Checa JC (2009) GD3 synthase overex-pression sensitizes hepatocarcinoma cells to hypoxia and reduces tumor growth by suppressing the cSrc/NF-kappaB survival pathway. PLoS One 4(11):e8059
15. Lee CW, Lin CC, Lin WN, Liang KC, Luo SF, Wu CB, Wang SW, Yang CM (2007) TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 292(3):L799-L812
16. Guha M, Mackman N (2001) (2001) LPS induction of gene expression in human monocytes. Cell Signal 13(2):85-94 (Pubitemid 32222977)
17. Hierholzer C, Harbrecht B, Menezes JM, Kane J, MacMicking J, Nathan CF, Peitzman AB, Billiar TR, Tweardy DJ (1998) Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J Exp Med 187(6):917-928 (Pubitemid 28141665)
18. Zingarelli B, Sheehan M, Wong HR (2003) Nuclear factor-kappaB as a therapeutic target in critical care medicine. Crit Care Med 31(1):S105-S111 (Pubitemid 36143484)
19. Gaddipati JP, Sundar SV, Calemine J, Seth P, Sidhu GS, Maheshwari RK (2003) Differential regulation of cytokines and transcription factors in liver by curcumin following hemorrhage/resuscitation. Shock 19(2):150-156
20. Baeuerle PA, Baltimore D (1998) A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB. Genes Dev 3(11):1689-1698
21. Hara Y (1994) Antioxidative action of tea polyphenols: Part 1. Am Biotechnol Lab 12(8):48
22. Zhao BL, Li XJ, He RG, Cheng SJ, Xin WJ (1989) Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals. Cell Biophys 14(2):175-185
23. Kuriyama S (2008) The relation between green tea consumption and cardiovascular disease as evidenced by epidemiological studies. J Nutr 138(8):1548S-1553S
24. Kuriyama S (2010) Green tea consumption and prevention of coronary artery disease. Circ J 74(2):248-249
25. Zhong Z, Froh M, Connor HD, Li X, Conzelmann LO, Mason RP, Lemasters JJ, Thurman RG (2002) Prevention of hepatic ischemia-reperfusion injury by green tea extract. Am J Physiol Gastrointest Liver Physiol 283(4):G957-G964 (Pubitemid 35033939)
26. Zhong Z, Connor HD, Froh M, Lind H, Bunzendahl H, Mason RP, Thurman RG, Lemasters JJ (2004) Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats. Free Radic Biol Med 36(10):1248-1258 (Pubitemid 38526319)
27. Fiorini RN, Donovan JL, Rodwell D, Evans Z, Cheng G, May HD, Milliken CE, Markowitz JS, Campbell C, Haines JK, Schmidt MG, Chavin KD (2005) Short-term administration of (-)-epigallocatechin gallate reduces hepatic steatosis and protects against warm hepatic ischemia/reperfusion injury in steatotic mice. Liver Transpl 11(3):298-308 (Pubitemid 40458402)
28. Relja B, Lehnert M, Seyboth K, Bormann F, Hohn C, Czerny C, Henrich D, Marzi I (2010) Simvastatin reduces mortality and hepatic injury after hemorrhage/resuscitation in rats. Shock 34(1):46-54
29. Lehnert M, Arteel GE, Smutney OM, Conzelmann LO, Zhong Z, Thurman RG, Lemasters JJ (2003) Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide. Shock 19(4):345-351
30. Lehnert M, Relja B, Sun-Young L V, Schwestka B, Henrich D, Czerny C, Froh M, Borsello T, Marzi I (2008) A peptide inhibitor of C-jun N-terminal kinase modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation. Shock 30(2):159-165
31. Jaeschke H, Mitchell JR (1989) Mitochondria and xanthine oxi-dase both generate reactive oxygen species in isolated perfused rat liver after hypoxic injury. Biochem Biophys Res Commun 160(1):140-147 (Pubitemid 19116473)
32. Granger DN, Benoit JN, Suzuki M, Grisham MB (1989) Leukocyte adherence to venular endothelium during ischemia-reperfusion. Am J Physiol 257(5 Pt 1):G683-G688
33. Jaeschke H, Bautista AP, Spolarics Z, Spitzer JJ (1992) Super-oxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats. J Leukoc Biol 52(4):377-382
34. Farber JL (1994) Mechanisms of cell injury by activated oxygen species. Environ Health Perspect 102(10):17-24
35. Gujral JS, Bucci TJ, Farhood A, Jaeschke H (2001) Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis? Hepatology 33(2):397-405 (Pubitemid 32119028)
36. Bendinelli P, Piccoletti R, Maroni P, Bernelli-Zazzera A (1996) The MAP kinase cascades are activated during post-ischemic liver reperfusion. FEBS Lett 398(2-3):193-197 (Pubitemid 26414308)
37. Chan ED, Winston BW, Jarpe MB, Wynes MW, Riches DW (1997) Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNF alpha. Proc Natl Acad Sci U S A 94(24):13169-13174 (Pubitemid 27518494)
38. McCloskey CA, Kameneva MV, Uryash A, Gallo DJ, Billiar TR (2004) Tissue hypoxia activates JNK in the liver during hemor-rhagic shock. Shock 22(4):380-386 (Pubitemid 39468980)
39. Westwick JK, Weitzel C, Leffert HL, Brenner DA (1995) Activation of Jun. kinase is an early event in hepatic regeneration. J Clin Invest 95(2):803-810
40. Lehnert M, Uehara T, Bradford BU, Lind H, Zhong Z, Brenner DA, Marzi I, Lemasters JJ (2006) Lipopolysaccharide-binding protein modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation. Am J Physiol Gas-trointest Liver Physiol 291(3):G456-G463 (Pubitemid 44330166)
41. Weston CR, Davis RJ (2007) The JNK signal transduction pathway. Curr Opin Cell Biol 19(2):142-149 (Pubitemid 46386399)
42. Minet E, Michel G, Mottet D, Piret JP, Barbieux A, Raes M, Michiels C (2001) c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells. Exp Cell Res 265(1):114-124 (Pubitemid 32989069)
43. Schreck R, Rieber P, Baeuerle PA (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J 10(8):2247-2258 (Pubitemid 21905698)
44. Dudek EJ, Shang F, Taylor A (2001) H (2) O (2)-mediated oxida-tive stress activates NF-kappa B in lens epithelial cells. Free Radic Biol Med 31(5):651-658 (Pubitemid 32777866)
45. Han YJ, Kwon YG, Chung HT, Lee SK, Simmons RL, Billiar TR, Kim YM (2001) Antioxidant enzymes suppress nitric oxide production through the inhibition of NF-kappa B activation: role of H (2) O (2) and nitric oxide in inducible nitric oxide synthase expression in macrophages. Nitric Oxide 5(5):504-513 (Pubitemid 32953600)
46. Hayden MS, Ghosh S (2004) Signaling to NF-kappaB. Genes Dev 18(18):2195-2224
47. Kubulus D, Mathes A, Reus E, Pradarutti S, Pavlidis D, Thierbach JT, Heiser J, Wolf B, Bauer I, Rensing H (2009) Endothelin-1 contributes to hemoglobin glutamer-200-mediated hepatocellular dysfunction after hemorrhagic shock. Shock 32(2):179-189
48. Vallabhaneni R, Kaczorowski DJ, Yaakovian MD, Rao J, Zuckerbraun BS (2010) Heme oxygenase-1 protects against hepatic hypoxia and injury from hemorrhage via regulation of cellular respiration. Shock 33(3):274-281
49. Meldrum DR, Shenkar R, Sheridan BC, Cain BS, Abraham E, Harken AH (1997) Hemorrhage activates myocardial NFkappaB and increases TNF-alpha in the heart. J Mol Cell Cardiol 29(10):2849-2854 (Pubitemid 27466506)
50. Ayuste EC, Chen H, Koustova E, Rhee P, Ahuja N, Chen Z, Valeri CR, Spaniolas K, Mehrani T, Alam HB (2006) Hepatic and pulmonary apoptosis after hemorrhagic shock in swine can be reduced through modifications of conventional Ringer's solution. J Trauma 60(1):52-63
51. Sundar SV, Li YY, Rollwagen FM, Maheshwari RK (2005) Hem-orrhagic shock induces differential gene expression and apoptosis in mouse liver. Biochem Biophys Res Commun 332(3):688-696 (Pubitemid 40745169)
52. Yang R, Martin-Hawver L, Woodall C, Thomas A, Qureshi N, Morrison D, Van WC, III (2007) Administration of glutamine after hemorrhagic shock restores cellular energy, reduces cell apoptosis and damage, and increases survival. JPEN J Parenter Enteral Nutr 31(2):94-100
53. Maitra SR, Bhaduri S, El-Maghrabi MR, Shapiro MJ (2005) Inhibition of matrix metalloproteinase on hepatic transforming growth factor beta1 and caspase-3 activation in hemorrhage. Acad Emerg Med 12(9):797-803 (Pubitemid 41191308)
54. Hurt RT, Zakaria R, Matheson PJ, Cobb ME, Parker JR, Garrison RN (2009) Hemorrhage-induced hepatic injury and hypoperfu-sion can be prevented by direct peritoneal resuscitation. J Gastrointest Surg 13(4):587-594
55. Uehara T, Xi P, Bennett B, Satoh Y, Friedman G, Currin R, Brenner DA, Lemasters J (2004) c-Jun. N-terminal kinase mediates hepatic injury after rat liver transplantation. Transplantation 78(3):324-332 (Pubitemid 39095396)
56. Guan QH, Pei DS, Liu XM, Wang XT, Xu TL, Zhang GY (2006) Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis. Brain Res 1092(1):36-46
57. Webster GA, Perkins ND (1999) Transcriptional cross talk between NF-kappaB and p53. Mol Cell Biol 19(5):3485-3495 (Pubitemid 29193808)
58. Barkett M, Gilmore TD (1999) Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 18(49):6910-6924
59. Kim JW, Jin YC, Kim YM, Rhie S, Kim HJ, Seo HG, Lee JH, Ha YL, Chang KC (2009) Daidzein administration in vivo reduces myocardial injury in a rat ischemia/reperfusion model by inhibiting NF-kappaB activation. Life Sci 84(7-8):227-234