Endothelin-1 contributes to hemoglobin glutamer-200-mediated hepatocellular dysfunction after hemorrhagic shock

Shock

Volumn 32, Issue 2, 2009, Pages 179-189

  Kubulus, Darius ^a   Mathes, Alexander ^a   Reus, Erik ^a   Pradarutti, Sascha ^a   Pavlidis, Daphne ^a   Thierbach, Jan Tobias ^a   Heiser, Jochen ^a   Wolf, Beate ^a   Bauer, Inge ^a   Rensing, Hauke ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Bosentan; Cytokine; Hemoglobin based oxygen carrier; Intravital microscopy; Microcirculation; Preconditioning

Indexed keywords

BOSENTAN; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; HEMOGLOBIN GLUTAMER 200; INDOCYANINE GREEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SUBSTITUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEMORRHAGIC SHOCK; IMMUNOHISTOCHEMISTRY; LIVER BLOOD FLOW; LIVER DYSFUNCTION; MALE; NONHUMAN; OXIDATION REDUCTION STATE; PATHOPHYSIOLOGY; RAT; REPERFUSION INJURY; RESUSCITATION;

ANIMALS; BLOOD SUBSTITUTES; CYTOKINES; DISEASE MODELS, ANIMAL; ENDOTHELIN-1; HEMOGLOBINS; HUMANS; ISOTONIC SOLUTIONS; LIVER; MALE; NADP; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SHOCK, HEMORRHAGIC; TIME FACTORS;

EID: 67749101218     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318199352b     Document Type: Article

References (41)

1. Mondoro TH, Alayash AI, Ryan BA, Terle DA, Vostal JG: Hemoglobin A0 and alpha-crosslinked hemoglobin (alpha-DBBF) potentiate agonist-induced platelet aggregation through the platelet thromboxane receptor. Artif Cells Blood Substit Immobil Biotechnol 26:1-16, 1998.
2. Everse J, Hsia N: The toxicities of native and modified hemoglobins. Free Radic Biol Med 22:1075-1099, 1997.
3. Sloan EP, Koenigsberg M, Gens D, Cipolle M, Runge J, Mallory MN, Rodman G: Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock: a randomized controlled efficacy trial. JAMA 282:1857-1864, 1999.
4. Saxena R, Wijnhoud AD, Carton H, Hacke W, Kaste M, Przybelski RJ, Stern KN, Koudstaal PJ: Controlled safety study of a hemoglobin-based oxygen carrier, DCLHb, in acute ischemic stroke. Stroke 30:993-996, 1999.
5. Driessen B, Zarucco L, Gunther RA, Burns PM, Lamb SV, Vincent SE, Boston RA, Jahr JS, Cheung AT: Effects of low-volume hemoglobin glutamer-200 versus normal saline and arginine vasopressin resuscitation on systemic and skeletal muscle blood flow and oxygenation in a canine hemorrhagic shock model. Crit Care Med 35:2101-2109, 2007.
6. King DR, Cohn SM, Proctor KG: Resuscitation with a hemoglobin-based oxygen carrier after traumatic brain injury. J Trauma 59:553-560, 2005.
7. Driessen B, Jahr JS, Lurie F, Golkaryeh MS, Gunther RA: Arterial oxygenation and oxygen delivery after hemoglobin-based oxygen carrier infusion in canine hypovolemic shock: a dose-response study. Crit Care Med 31:1771-1779, 2003.
8. Kubulus D, Rensing H, Paxian M, Thierbach JT, Meisel T, Redl H, Bauer M, Bauer I: Influence of heme-based solutions on stress protein expression and organ failure after hemorrhagic shock. Crit Care Med 33:629-637, 2005.
9. Winslow RM: alphaalpha-crosslinked hemoglobin: was failure predicted by preclinical testing? Vox Sang 79:1-20, 2000.
10. Olson JS, Foley EW, Rogge C, Tsai AL, Doyle MP, Lemon DD: No scavenging and the hypertensive effect of hemoglobin-based blood substitutes. Free Radic Biol Med 36:685-697, 2004.
11. Winslow RM: Current status of blood substitute research: towards a new paradigm. J Intern Med 253:508-517, 2003.
12. Cocks TM, Malta E, King SJ, Woods RL, Angus JA: Oxyhaemoglobin increases the production of endothelin-1 by endothelial cells in culture. Eur J Pharmacol 196:177-182, 1991.
13. Ohlstein EH, Storer BL: Oxyhemoglobin stimulation of endothelin production in cultured endothelial cells. J Neurosurg 77:274-278, 1992.
14. Lin G, Macdonald RL, Marton LS, Kowalczuk A, Solenski NJ, Weir BK: Hemoglobin increases endothelin-1 in endothelial cells by decreasing nitric oxide. Biochem Biophys Res Commun 280:824-830, 2001.
15. Duvigneau JC, Piskernik C, Haindl S, Kloesch B, Hartl RT, Huttemann M, Lee I, Ebel T, Moldzio R, Gemeiner M, et al.: A novel endotoxin-induced pathway: upregulation of heme oxygenase 1, accumulation of free iron, and free iron-mediated mitochondrial dysfunction. Lab Invest 88:70-77, 2008.
16. Goldman DW, Breyer RJ III, Yeh D, Brockner-Ryan BA, Alayash AI: Acellular hemoglobin-mediated oxidative stress toward endothelium: a role for ferryl iron. Am J Physiol 275:H1046-H1053, 1998.
17. Sabaa N, de Franceschi L, Bonnin P, Castier Y, Malpeli G, Debbabi H, Galaup A, Maier-Redelsperger M, Vandermeersch S, Scarpa A, et al.: Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease. J Clin Invest 118:1924-1933, 2008.
18. Paxian M, Rensing H, Geckeis K, Bauer I, Kubulus D, Spahn DR, Bauer M: Perflubron emulsion in prolonged hemorrhagic shock: influence on hepatocellular energy metabolism and oxygen-dependent gene expression. Anesthesiology 98:1391-1399, 2003.
19. Vollmar B, Burkhardt M, Minor T, Klauke H, Menger MD: High-resolution microscopic determination of hepatic NADH fluorescence for in vivo monitoring of tissue oxygenation during hemorrhagic shock and resuscitation. Microvasc Res 54:164-173, 1997.
20. Zimmerhackl B, Parekh N, Brinkhus H, Steinhausen M: The use of fluorescent labeled erythrocytes for intravital investigation of flow and local hematocrit in glomerular capillaries in the rat. Int J Microcirc Clin Exp 2:119-129, 1983.
21. Bauer M, Zhang JX, Bauer I, Clemens MG: Endothelin-1 as a regulator of hepatic microcirculation: sublobular distribution of effects and impact on hepatocellular secretory function. Shock 1:457-465, 1994.
22. Clemens MG, Bauer M, Pannen BH, Bauer I, Zhang JX: Remodeling of hepatic microvascular responsiveness after ischemia/reperfusion. Shock 8:80-85, 1997.
23. Carrico CJ, Holcomb JB, Chaudry IH: Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group. Shock 17:165-168, 2002.
24. Levy JH: The use of haemoglobin glutamer-250 (HBOC-201) as an oxygen bridge in patients with acute anaemia associated with surgical blood loss. Expert Opin Biol Ther 3:509-517, 2003.
25. Schultz SC, Grady B, Cole F, Hamilton I, Burhop K, Malcolm DS: A role for endothelin and nitric oxide in the pressor response to diaspirin cross-linked hemoglobin. J Lab Clin Med 122:301-308, 1993.
26. Doherty DH, Doyle MP, Curry SR, Vali RJ, Fattor TJ, Olson JS, Lemon DD: Rate of reaction with nitric oxide determines the hypertensive effect of cell-free hemoglobin. Nat Biotechnol 16:672-676, 1998.
27. Winslow RM: Alternative oxygen therapeutics: products, status of clinical trials, and future prospects. Curr Hematol Rep 2:503-510, 2003.
28. Rubanyi GM, Polokoff MA: Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev 46:325-415, 1994.
29. Sonin NV, Garcia-Pagan JC, Nakanishi K, Zhang JX, Clemens MG: Patterns of vasoregulatory gene expression in the liver response to ischemia/reperfusion and endotoxemia. Shock 11:175-179, 1999.
30. Yokoyama Y, Baveja R, Sonin N, Nakanishi K, Zhang JX, Clemens MG: Altered endothelin receptor subtype expression in hepatic injury after ischemia/reperfusion. Shock 13:72-78, 2000.
31. Smani Y, Faivre B, Udonnet-Blaise S, Labrude P, Vigneron C: Hemoglobin-based oxygen carrier distribution inside vascular wall and arterial pressure evolution: is there a relationship? Eur Surg Res 37:1-8, 2005.
32. Milici AJ, Bankston PW: Fetal and neonatal rat intestinal capillaries: permeability to carbon, ferritin, hemoglobin, and myoglobin. Am J Anat 165:165-186, 1982.
33. Keipert PE, Gomez CL, Gonzales A, Macdonald VW, Hess JR, Winslow RM: Diaspirin cross-linked hemoglobin: tissue distribution and long-term excretion after exchange transfusion. J Lab Clin Med 123:701-711, 1994.
34. Fink MP: Cytopathic hypoxia. Mitochondrial dysfunction as mechanism contributing to organ dysfunction in sepsis. Crit Care Clin 17:219-237, 2001.
35. Bauer M, Bauer I: Heme oxygenase-1: redox regulation and role in the hepatic response to oxidative stress. Antioxid Redox Signal 4:749-758, 2002.
36. Plevris JN, Jalan R, Bzeizi KI, Dollinger MM, Lee A, Garden OJ, Hayes PC: Indocyanine green clearance reflects reperfusion injury following liver transplantation and is an early predictor of graft function. J Hepatol 30:142-148, 1999.
37. Gottlieb ME, Sarfeh IJ, Stratton H, Goldman ML, Newell JC, Shah DM: Hepatic perfusion and splanchnic oxygen consumption in patients postinjury. J Trauma 23:836-843, 1983.
38. Caesar J, Shaldon S, Chiandussi L, Guevara L, Sherlock S: The use of indocyanine green in the measurement of hepatic blood flow and as a test of hepatic function. Clin Sci 21:43-57, 1961.
39. Conte FP, Barja-Fidalgo C, Verri WA Jr, Cunha FQ, Rae GA, Penido C, Henriques MG: Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1. J Leukoc Biol 84:652-660, 2008.
40. Gamze K, Mehmet HM, Deveci F, Turgut T, Ilhan F, Ozercan I: Effect of bosentan on the production of proinflammatory cytokines in a rat model of emphysema. Exp Mol Med 39:614-620, 2007.
41. Kirkil C, Cetinkaya Z, Ustundag B, Akpolat N, Ayten R, Bulbuller N: The effects of endothelin receptor blockade by bosentan on the healing of a bowel anastomosis in an experimental Crohn's disease model. J Gastrointest Surg 12:1429-1435, 2008.