TNF-α induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-κB/p300 binding in human tracheal smooth muscle cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 3, 2007, Pages

  Lee, Chiang Wen ^a   Lin, Chih Chung ^a   Lin, Wei Ning ^a   Liang, Kao Chih ^a   Luo, Shue Feng ^a   Wu, Chow Bin ^a   Wang, Shyi Wu ^a   Yang, Chuen Mao ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Chromatin remodeling; Histone modifications; Transactivation of growth factor receptors; Transcription factors

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 6,7 DIMETHOXY 2 PHENYLQUINOXALINE; CURCUMIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; HISTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN P300; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; NUCLEOTIDE SEQUENCE; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; TRACHEA MUSCLE; WESTERN BLOTTING; ZYMOGRAPHY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; E1A-ASSOCIATED P300 PROTEIN; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOPRECIPITATION; MATRIX METALLOPROTEINASE 9; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRACHEA; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33847750253     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00311.2006     Document Type: Article

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