Postinjury Multiple Organ Failure: A Bimodal Phenomenon

Journal of Trauma - Injury, Infection and Critical Care

Volumn 40, Issue 4, 1996, Pages 501-510

  Moore, Frederick A ^a,b   Sauaia, Angela ^a   Moore, Ernest E ^a   Haenel, James B ^a   Burch, Jon M ^a   Lezotte, Dennis C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Dysfunctional; Early multiple organ failure; Inflammation; Late multiple organ failure; Multiple organ failure; Postinjury pneumonia; Postinjury systemic inflammatory response syndrome

Indexed keywords

ADULT; ARTICLE; CLINICAL FEATURE; FEMALE; HEART DISEASE; HUMAN; INCIDENCE; INJURY; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; MULTIPLE ORGAN FAILURE; PRIORITY JOURNAL; RISK ASSESSMENT; SHOCK;

ADOLESCENT; ADULT; FEMALE; HUMANS; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; PROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS; WOUNDS AND INJURIES;

EID: 0029986567     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/00005373-199604000-00001     Document Type: Article

References (63)

1. Baue AE: Multiple progressive, or sequential systems failure. Arch Surg 110:779, 1975
2. Walker L, Eiseman B: The changing pattern of posttraumatic respiratory distress syndrome. Ann Surg 181:693, 1976
3. Eiseman B, Beart R, Norton L: Multiple organ failure. Surg Gynecol Obstet 144:323, 1977
4. Baker CC, Oppenheimer L, Stephens B, et al: Epidemiology of trauma deaths: Am J Surg 140:144, 1980
5. Moore FA, Moore EE: Trauma Resuscitation. In Wilmore DW, Brennan MF, Harken AH, et al (eds): Scientific American Surgery. New York, Scientific American, 1995, pp 1-63
6. Shackford SR, MacKersie RC, Holbrook TL, et al: The epidemiology of traumatic death. Arch Surg 128:571, 1993
7. Sauaia A, Moore FA, Moore EE, et al: Early predictors of postinjury multiple organ failure. Arch Surg 129:39, 1994
8. Sauaia A, Moore FA, Moore EE, et al: Epidemiology of trauma deaths: A reassessment. J Trauma 38:185, 1995
9. Lauwers LF, Roelant A, Beeckman C, et al: A retrospective study of 130 consecutive multiple trauma patients in an intensive care unit. Intensive Care Med 12:296, 1986
10. Crump JM, Duncan DA, Wears R: Analysis of multiple organ system failure in trauma and nontrauma patients. Am J Surg 54:702, 1988
11. Goins WA, Reynolds HN, Nyanjom D et al: Outcome following prolonged intensive care unit stay in multiple trauma patients. Crit Care Med 19:339, 1991
12. Henao FJ, Daes JE, Dennis RJ: Risk factors for multiorgan failure: A case control study. J Trauma 31:75, 1991
13. Waydhas C, Nost-Kolb D, Jochum M, et al: Inflammatory mediators, infection, sepsis, and multiple organ failure after severe trauma. Arch Surg 127:460, 1992
14. Tran DD, Cuesta MA, Leeuwen PA, et al: Risk factors for multiple organ system failure and death in critically injured patients. Surgery 114:21, 1993
15. Regel G, Lobenhoffer P, Grotz M, et al: Treatment results of patients with multiple trauma: An analysis of 3406 cases treated between 1972 and 1991 at a German level I trauma center. J Trauma 38:70, 1995
16. Baue AE (ed): Multiple Organ Failure: Patient Care and Prevention. St. Louis, Mosby Year Book, 1990
17. Fry DE (ed): Multiple System Organ Failure. St. Louis, Mosby Year Book, 1992
18. Demling R, LaLonde C, Saldinger P, et al: Multiple-organ dysfunction in the surgical patient: Pathophysiology, prevention and treatment. Curr Probl Surg 30:347, 1993
19. Moore FA, Moore EE: Evolving concepts in the pathogenesis of postinjury multiple organ failure. Surg Clin North Am 75:257, 1995
20. Sauaia A, Moore FA, Moore EE, et al: Early risk factors for postinjury multiple organ failure. World J Surg. In press
21. Polk HC, Shields CL: Remote organ failure: A valid sign of occult intra-abdominal infection. Surgery 81:310, 1977
22. Fry DE, Pearlstein L, Fulton RL, et al: Multiple system organ failure: The role of uncontrolled infection. Arch Surg 115:136, 1980
23. Bell RC, Coalson JJ, Smith JD, et al: Multiple organ system failure and infection in adult respiratory distress syndrome. Ann Intern Med 99:293, 1983
24. Faist E, Baue AE, Mittmer H, et al: Multiple organ failure in polytrauma patients. J Trauma 23:775, 1983
25. Goris JA, Boekhoerst TP, Nuytinck JK, et al: Multiple organ failure. Arch Surg 120:1109, 1985
26. Montgomery Ab, Stager MA, Carrico J, et al: Cause of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis 132:485, 1985
27. Villar J, Manzano JJ, Blazsquez MA, et al: Multiple system organ failure in acute respiratory failure. J Crit Care 6:75, 1991
28. Murray JF, Mallhay MA, Luce JM, et al: An expanded definition of the adult respiratory distress syndrome. Am Rev Respiratory Dis 138:720, 1988
29. Bernard GR, Artigas A, Brigham KL, et al: Report of the American-European Consensus Conference on Acute Respiratory Distress Syndrome: Definitions, mechanisms, relevant outcome and clinical trial coordination. J Crit Care 8:1, 1993
30. Moore FA, Moore EE, Poggetti R, et al: Gut bacterial translocation via the portal vein: A clinical perspective with major torso trauma. J Trauma 31:629, 1991
31. Knaus WA, Wagner DP, Draper EA, et al: The APACHE III prognostic system: Risk prediction of hospital mortality for critically ill hospitalized adults. Chest 100:1619, 1991
32. Milzman DP, Hinson D, Magnant CM: Trauma and preexisting diseases: Overview and outcome. Crit Care Clin 9:633, 1993
33. 33: The Abbreviated Injury Scale 1990 Revision. De Plaines, Ill, Association for the Advancement of Automotive Medicine, 1991
34. Gainec JC, Jarvis WR, Horan TC, et al: CDC definitions for nosocomial infections. Am J Infect Control 16:128, 1988
35. Sauaia A, Moore FA, Moore EE, et al: Pneumonia: Cause or symptom of postinjury multiple organ failure? Am J Surg 166:607, 1993
36. Fry DE (ed): A symposium: The continued challenge of trauma and infections in surgery. Am J Surg 165:1S, 1993
37. Stillwell M, and Caplan ES: The septic multiple-trauma patient. Infect Dis Clin North Am 3:155, 1989
38. Hoch RC, Rodriguez R, Manning T, et al: Effects of accidental trauma on cytokine and endotoxin production. Crit Care Med 21:839, 1993
39. Bone RC, Balk RAA, Cerra FB, et al: American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20:864, 1992
40. Bone RC, Balk R, Slotman G, et al: Adult respiratory distress syndrome: Importance of development of multiple organ failure. Chest 10:3320, 1992
41. Moore FA, Peterson VM, and Moore EE: Inadequate granulopoieses after major torso trauma: A hematopoietic regulatory paradox. Surgery 108:667, 1990
42. Moore EE, Moore FA, Franciose RJ, et al: Postischemic gut serves as a priming bed for circulating neutrophils that provoke multiple organ failure. J Trauma 37:881, 1994
43. Botha AJ, Moore FA, Moore EE, et al: Early postinjury neutrophil priming and activation: A vulnerable window. Surgery 118:358, 1995
44. Botha AJ, Moore FA, Moore EE, et al: Early neutrophil sequestration after injury: A pathologic mechanism for multiple organ failure. J Trauma 39:411, 1995
45. Polk HC Jr, George CD, Wellhausen SR, et al: A systematic study of host defense processes in badly injured patients. Ann Surg 204:282, 1986
46. 2)-dependent suppression of interleukin alpha (IL2) production in patients with major trauma. J Trauma 27:837, 1987
47. Chaudry IH, Ayala A: Immunologic Aspects of Hemorrhage. Austin, Tex, RG Landes, 1992
48. Cronin L, Cook DJ, Carlet J, et al: Corticosteroid treatment of sepsis: A critical appraisal and meta-analysis of the literature. Crit Care Med 23:1430, 1995
49. Fisher CJ, Slatman GJ, Opal SM, et al: Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: A randomized, open-label, placebo-controlled multicenter trial. Crit Care Med 22:12, 1994
50. Fisher CJ, Opal SM, Dhainaut J, et al: Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis. Crit Care Med 21:318, 1993
51. Bone RC, Bolk RA, Fein AM, et al: A second large controlled clinical study of E%, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial. Crit Care Med 23:994, 1995
52. Border JR, Hassett J, LaDuca J, et al: The gut origin septic states in blunt multiple trauma (ISS = 40) in the ICU. Ann Surg 206:427, 1987
53. Marshall, JC, Christou NV, Meakins JL: The gastrointestinal tract: The "undrained abscess" of multiple organ failure. Ann Surg 218:111, 1993
54. Moore FA, Feliciano DV, Andrassy RJ, et al: Early enteral feeding, compared with parenteral, reduces postoperative septic complications. Ann Surg 216:172, 1992
55. Moore FA, Moore EE, Kudsk KA, et al: Clinical benefits of an immune-enhancing diet for early postinjury enteral feeding. J Trauma 37:607, 1994
56. 56: Van Saene HKF, Stoutenbeek CC, et al: Selective decontamination of the digestive tract in the intensive care unit: Current status and future prospects. Crit Care Med 20:691, 1992
57. Heyland DK, Cook DJ, Jaeschke A, et al: Selective decontamination of the digestive tract: An overview. Chest 105:1221, 1994
58. Cerra FB, Maddaus MA, Dunn DL, et al: Selective gut decontamination reduces nosocomial infections and length of stay but not mortality or organ failure in surgical intensive care unit patients. Arch Surg 127:163, 1992
59. Sauaia A, Moore FA, Moore EE, et al: Pneumonia related multiple organ failure is not a primary cause of death in head trauma. Pan Am J Trauma 3:90, 1992
60. Sauaia A, Moore FA, Moore EE, et al: Diagnosing pneumonia in mechanically ventilated trauma patients: Endotracheal aspirate versus bronchoalveolar lavage. J Trauma 35:512, 1993
61. Biffl WL, Moore FA, Moore EE, et al: Are corticosteroids salvage therapy for refractory ARDS? Am J Surg. 170:591, 1995
62. Ashbaugh DG, Maier RV: Diopathic pulmonary fibrosis in adult respiratory distress syndrome. Arch Surg 120:530, 1985
63. Meduri GU, Chinn AJ, Leeper KV, et al: Corticosteroids rescue treatment of fibroproliferative ARDS. Chest 105:1516, 1994